Plasma Proteome Profiles Associated with Diet-Induced Metabolic Syndrome and the Early Onset of Metabolic Syndrome in a Pig Model

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  te Pas, Marinus F W ^a   Koopmans, Sietse Jan ^a   Kruijt, Leo ^a   Calus, Mario P L ^a   Smits, Mari A ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL; FATTY ACID; GLUCOSE; HIGH DENSITY LIPOPROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN; PROTEOME; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ABDOMINAL FAT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOHYDRATE DIET; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DIABETES MELLITUS; EARLY DIAGNOSIS; GLUCOSE BLOOD LEVEL; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; LIPID DIET; LIPID METABOLISM; LIPID STORAGE; LIPOPROTEIN BLOOD LEVEL; MALE; MEDITERRANEAN DIET; METABOLIC SYNDROME X; NONHUMAN; PROTEIN EXPRESSION; PROTEOMICS; SWINE; TRIACYLGLYCEROL BLOOD LEVEL;

AGE OF ONSET; ANIMALS; BLOOD PROTEINS; DIET; DISEASE MODELS, ANIMAL; METABOLIC SYNDROME X; PROTEOME; SWINE;

EID: 84884540882     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073087     Document Type: Article

References (26)

1. Perrini S, Laviola L, Cignarelli A, Melchiorre M, De Stefano F, et al. (2008) Fat depot-related differences in gene expression, adiponectin secretion, and insulin action and signaling in human adipocytes differentiated in vitro from precursor stromal cells. Diabetologia 51: 155-164.
2. Lam QL, Lu L, (2007) Role of leptin in immunity. Cell Mol Immunol 4: 1-13.
3. Osborn O, Olefsky JM, (2012) The cellular and signaling networks linking the immune system and metabolism in disease. Nature Med 18: 363-374.
4. Zhang Y, Guo KY, Diaz PA, Heo M, Leibel RL, (2002) Determinants of leptin gene expression in fat depots of lean mice. Am J Physiol Regul Integr Comp Physiol 282: R226-R234.
5. Kahn BB, Flier JS, (2000) Obesity and insulin resistance. J Clin Invest 106: 473-481.
6. Hardie DG, Ross FA, Hawley SA, (2012) AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nature Rev Mol Cell Biol 13: 251-262.
7. Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, et al. (2012) Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature 483(7389): 350-354.
8. Dherty MK, Beynon RJ, Whitfield PD, (2008) Proteomics and naturally occurring animal diseases: Opportunities for animal and human medicine. Proteomics Clin Appl 2: 135-141.
9. Kussmann M, Raymond F, Affolter M, (2006) OMICS-driven biomarker discovery in nutrition and health. J Biotechnol 124: 758-787.
10. Rao PV, Reddy AP, Lu X, Dasari S, Krishnaprasad A, et al. (2009) Proteomic Identification of Salivary Biomarkers of Type-2 Diabetes. J Proteome Res 8: 239-245.
11. Sundsten T, Ortsäter H, (2009) Proteomics in diabetes research. Mol Cell Endocrinol 297: 93-103.
12. Koopmans SJ, Dekker R, Ackermans MT, Sauerwein HP, Serlie MJ, et al. (2011) Dietary saturated fat/cholesterol, but not unsaturated fat or starch, induces C-reactive protein associated early atherosclerosis and ectopic fat deposition in diabetic pigs. Cardiovasc Diabet 10: 64 Available: http://www.cardiab.com/content/10/1/64.
13. Van den Heuvel M, Sorop O, Koopmans SJ, Dekker R, de Vries R, et al. (2012) Coronary microvascular dysfunction in a porcine model of early atherosclerosis and diabetes. Am J Physiol Heart Circ Physiol 302: H85-H94.
14. Groenen MAM, Archibald AL, Uenish H, Tuggle CK, Takeuchi Y, et al. (2012) Analyses of pig genomes provide insight into porcine demography and evolution. Nature 491, 393-398.
15. Merks JWM (2000) One century of genetic changes in pigs and the future needs. In: Hill WG, Bishop SC, McGuirk B, McKay JC, Simm G, Webb AJ, editors.The Challenge of Genetic Change in Animal Production. Occasional Publication., No. 27. Edinburgh, UK., Br. Soc. Anim. Sci., 8-19.
16. Vodicka P, Smetana K Jr, Dvoránková B, Emerick T, Xu YZ, et al. (2005) The miniature pig as an animal model in biomedical research. Ann N Y Acad Sci 1049: 161-171.
17. Bell LN, Lee L, Saxena R, Bemis KG, Wang M, et al. (2010) Serum proteomic analysis of diet-induced steatohepatitis and Metabolic syndrome in the Ossabaw miniature swine. Am J Physiol Gastrointest Liver Physiol 298: G746-G754.
18. Kilkenny C, Browne WJ, Cuthill IC, Emerson M, Altman DG, (2010) Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research. PLoS Biol 8(6): e1000412.
19. Rossini A, Like AA, Chick WL, Appel MC, Cahill GF Jr, (1977) Studies of streptozotocin-induced insulitis and diabetes. Proc Nat Acad Sci USA 74 (6) (): 2485-2489.
20. Szkudelski T, (2001) The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 50: 537-546.
21. Mansford KR, Opie L, (1968) Comparison of metabolic abnormalities in diabetes mellitus induced by streptozotocin or by alloxan. Lancet 1: 670-671 DOI:10.1016/S0140-6736(68)92103-X. PMID 4170654.
22. Rerup CC, (1970) Drugs producing diabetes through damage of the insulin secreting cells. Pharmacol Rev 22: 485-518.
23. Koopmans SJ, Mroz Z, Dekker R, Corbijn H, Ackermans M, et al. (2006) Association of insulin resistance with hyperglycemia in streptozotocindiabetic pigs. Effects of metformin at soenergetic feeding in a type 2-like diabetic pig model. Metabolism 55: 960-971.
24. Mach N, Keuning E, Kruijt L, Hortós M, Arnau J, et al. (2010) Comparative proteomic profiling of two muscles from five divergent pig breeds using SELDI-TOF proteomics technology. J Anim Sci 88: 1522-1534.
25. Moore RE, Kirwan J, Doherty MK, Whitfield PD, (2007) Biomarker Discovery in Animal Health and Disease: The Application of Post-Genomic Technologies. Biomark Insight 2: 185-196.
26. Liotta LA, Ferrari M, Petricoin E, (2003) Clinical proteomics: Written in blood. Nature 425: 905.