Serum proteomic analysis of diet-induced steatohepatitis and metabolic syndrome in the Ossabaw miniature swine

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 298, Issue 5, 2010, Pages

  Bell, Lauren N ^a   Lee, Lydia ^a   Saxena, Romil ^a   Bemis, Kerry G ^a   Wang, Mu ^a   Theodorakis, Janice L ^a   Vuppalanchi, Raj ^a   Alloosh, Mouhamad ^a   Sturek, Michael ^a   Chalasani, Naga ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Animal model; Fatty liver disease; Fibrosis; Mass spectrometry; Nonalcoholic steatohepatitis

Indexed keywords

ALPHA 2 MACROGLOBULIN; AMYLOID P COMPONENT; APOLIPOPROTEIN B; APOLIPOPROTEIN C; APOLIPOPROTEIN C3; APOLIPOPROTEIN E; ARYLDIALKYLPHOSPHATASE 1; BETA 2 MICROGLOBULIN; CARBOXYPEPTIDASE B; OROSOMUCOID; PLASMA PROTEIN; PREALBUMIN; PROTEIN PRECURSOR; PROTEINASE; PROTEOME; SCLEROPROTEIN; STRUCTURAL PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENIC DIET; CONTROLLED STUDY; DISEASE SEVERITY; FATTY LIVER; FEMALE; IMMUNOREGULATION; INFLAMMATION; LIPID METABOLISM; LIVER HISTOLOGY; MALE; METABOLIC SYNDROME X; MINIPIG; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS;

ANIMALS; DIET, ATHEROGENIC; FATTY LIVER; FEMALE; HUMANS; MALE; METABOLIC SYNDROME X; MODELS, ANIMAL; PROTEOMICS; SWINE; SWINE, MINIATURE;

EID: 77951492476     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00485.2009     Document Type: Article

References (36)

1. American Veterinary Medical Association Panel on Euthanasia. Report of the AVMA panel on euthanasia. J Am Vet Med Assoc 218: 669-696, 2001.
2. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 346: 1221-1231, 2002.
3. Bacon BR, Farahvash MJ, Janney CG, Neuschwander-Terri BA. Nonalcoholic steatohepatitis: an expanded clinical entity. Gastroenterology 107: 1103-1109, 1994.
4. Bell LN, Theodorakis JL, Vuppalanchi R, Bemis KG, Wang M, Chalasani N. Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease. Hepatology 51: 111-120, 2009.
5. Bolstad BM, Irizarry RA, Astrand M, Speed TP. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 19: 185-193, 2003. (Pubitemid 36181903)
6. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
7. Camps J, Marsillach J, Joven J. The paraoxonases: role in human diseases and methodological difficulties in measurement. Crit Rev Clin Lab Sci 46: 83-106, 2009.
8. Craig R, Beavis RC. TANDEM: matching proteins with tandem mass spectra. Bioinformatics 20: 1466-1467, 2004. (Pubitemid 38931421)
9. Deban L, Bottazzi B, Garlanda C, de la Torre YM, Mantovani A. Pentraxins: multifunctional proteins at the interface of innate immunity and inflammation. Biofactors 35: 138-145, 2009.
10. Dyson M, Alloosh M, Vuchetich JP, Mokelke EA, Sturek M. Components of metabolic syndrome and coronary artery disease in female Ossabaw swine fed excess atherogenic diet. Comp Med 56: 35-45, 2006.
11. Eng J, McCormack A, Yates RR. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom 5: 976-989, 1994.
12. Hale JE, Butler JP, Gelfanova V, You JS, Knierman MD. A simplified procedure for the reduction and alkylation of cysteine residues in proteins prior to proteolytic digestion and mass spectral analysis. Anal Biochem 333: 174-181, 2004. (Pubitemid 39209235)
13. Helling TS, Helzberg JH, Nachnani JS, Gurram K. Predictors of nonalcoholic steatohepatitis in patients undergoing bariatric surgery: when is liver biopsy indicated? Surg Obes Relat Dis 4: 612-617, 2008.
14. Higgs RE, Knierman MD, Gelfanova V, Butler JP, Hale JE. Comprehensive label-free method for the relative quantification of proteins from biological samples. J Proteome Res 4: 1442-1450, 2005. (Pubitemid 41208703)
15. Higgs RE, Knierman MD, Freeman AB, Gelbert LM, Patil ST, Hale JE. Estimating the statistical significance of peptide identifications from shotgun proteomics experiments. J Proteome Res 6: 1758-1767, 2007.
16. Koruk M, Taysi S, Savas MC, Yilmaz O, Akcay F, Karakok M. Serum levels of acute phase proteins in patients with nonalcoholic steatohepatitis. Turk J Gastroenterol 14: 12-17, 2003. (Pubitemid 36569840)
17. Lee L, Alloosh M, Saxena R, Van Alstine W, Watkins BA, Klaunig JE, Sturek M, Chalasani N. Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine. Hepatology 50: 56-67, 2009.
18. Loria P, Carulli L, Bertolotti M, Lonardo A. Endocrine and liver interaction: the role of endocrine pathways in NASH. Nat Rev Gastroenterol Hepatol 6: 236-347, 2009.
19. Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Liu YC, McCullough AJ. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 116: 1413-1419, 1999. (Pubitemid 29258890)
20. National Research Council. Guide for the Care and Use of Laboratory Animals. Washington, DC: National Academy Press, 1996.
21. Ono M, Shitashige M, Honda K, Isobe T, Kuwabara H, Matsuzuki H, Hirohashi S, Yamada T. Label-free quantitative proteomics using large peptide data sets generated by nanoflow liquid chromatography and mass spectrometry. Mol Cell Proteomics 5: 1338-1347, 2006. (Pubitemid 44103403)
22. Otis CR, Wamhoff BR, Sturek M. Hyperglycemia-induced insulin resistance in diabetic dyslipidemic Yucatan swine. Comp Med 53: 53-64, 2003. (Pubitemid 36323514)
23. Pavlic M, Valéro R, Duez H, Xiao C, Szeto L, Patterson BW, Lewis GF. Triglyceride-rich lipoprotein-associated apolipoprotein C-III production is stimulated by plasma free fatty acids in humans. Arterioscler Thromb Vasc Biol 28: 1660-1665, 2008. (Pubitemid 351653555)
24. Qin X, Gao B. The complement system in liver diseases. Cell Mol Immunol 3: 333-340, 2006.
25. Ratziu V, Massard J, Charlotte F, Messous D, Imbert-Bismut F, Bonyhay L, Tahiri M, Munteanu M, Thabut D, Cadranel JF, Le Bail B, de Ledinghen V, Poynard T, LIDO Study Group, CYTOL study group. Diagnostic value of biochemical markers (FibroTest-FibroSURE) for the prediction of liver fibrosis in patients with non-alcoholic fatty liver disease. BMC Gastroenterol 6: 6-18, 2006. (Pubitemid 43308995)
26. Richardson MR, Lai X, Dixon JL, Sturek M, Witzmann FA. Diabetic dyslipidemia and exercise alter the plasma low density lipoproteome in Yucatan pigs. Proteomics 9: 2468-2483, 2008.
27. St. Pierre AC, Cantin B, Dagenais GR, Despres JP, Lamarche B. Apolipoprotein-B, low-density lipoprotein cholesterol, and the long-term risk of coronary heart disease in men. Am J Cardiol 97: 997-1001, 2006.
28. Sturek M, Alloosh M, Wenzel J, Byrd JP, Edwards JM, Lloyd PG. Ossabaw Island miniature swine: cardiometabolic syndrome assessment. In: Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, edited by Swindle MM. Boca Raton, FL: CRC, 2007.
29. Swindle MM. Swine in the Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques. Boca Raton, FL: CRC, 2007.
30. Teli MR, James OF, Burt AD, Bennett MK, Day CP. The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 22: 1714-1719, 1995.
31. Wang G, Wu WW, Zeng W, Chou CL, Shen RF. Label-free protein quantification using LC-coupled ion trap or FT mass spectrometry: reproducibility, linearity, and application with complex proteomes. J Proteome Res 5: 1214-1223, 2006. (Pubitemid 43727800)
32. Wang M, You J, Bemis KG, Tegeler TJ, Brown DP. Label-free mass spectrometry-based protein quantification technologies in proteomic analysis. Brief Funct Genomic Proteomic 7: 329-339, 2008.
33. Yan W, Chen SS. Mass spectrometry-based quantitative proteomic profiling. Brief Funct Genomic Proteomic 4: 27-38, 2005. (Pubitemid 40724165)
34. Yoneda M, Mawatari H, Fujita K, Iida H, Yonemitsu K, Kato S, Takahashi H, Kirikoshi H, Inamori M, Nozaki Y, Abe Y, Kubota K, Saito S, Iwasaki T, Terauchi Y, Togo S, Maeyama S, Nakajima A. High-sensitivity C-reactive protein is an independent clinical feature of nonalcoholic steatohepatitis (NASH) and also of the severity of fibrosis in NASH. J Gastroenterol 42: 573-582, 2007. (Pubitemid 47190075)
35. Yoneda M, Nozaki Y, Endo H, Mawatari H, Iida H, Fujita K, Yoneda K, Takahashi H, Kirikoshi H, Inamori M, Kobayashi N, Kubota K, Saito S, Maeyama S, Hotta K, Nakajima A. Serum ferritin is a clinical biomarker in Japanese patients with nonalcoholic steatohepatitis (NASH) independent of HFE gene mutation. Dig Dis Sci 55: 808-814, 2009.
36. Zhang B, VerBerkmoes NC, Langston MA, Uberbacher E, Hettich RL, Samatova NF. Detecting differential and correlated protein expression in label-free shotgun proteomics. J Proteome Res 5: 2909-2918, 2006. (Pubitemid 44749209)