-
1
-
-
22144472218
-
Dynamic changes in fat oxidation in human primary myocytes mirror metabolic characteristics of the donor
-
DOI 10.1172/JCI24332
-
Ukropcova B, McNeil M, Sereda O, de Jonge L, Xie H, Bray GA, Smith SR 2005 Dynamic changes in fat oxidation in human primary myocytes mirror metabolic characteristics of the donor. J Clin Invest 115:1934-1941 (Pubitemid 40979733)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.7
, pp. 1934-1941
-
-
Ukropcova, B.1
McNeil, M.2
Sereda, O.3
De, J.L.4
Xie, H.5
Bray, G.A.6
Smith, S.R.7
-
2
-
-
77951162397
-
Compensatory increases in nuclear PGC1α protein are primarily associated with subsarcolemmal mitochondrial adaptations in ZDF rats
-
Holloway GP, Gurd BJ, Snook LA, Lally J, Bonen A 2010 Compensatory increases in nuclear PGC1α protein are primarily associated with subsarcolemmal mitochondrial adaptations in ZDF rats. Diabetes 59:819-828
-
(2010)
Diabetes
, vol.59
, pp. 819-828
-
-
Holloway, G.P.1
Gurd, B.J.2
Snook, L.A.3
Lally, J.4
Bonen, A.5
-
3
-
-
45549089279
-
High-fat diets cause insulin resistance despite an increase in muscle mitochondria
-
DOI 10.1073/pnas.0802057105
-
Hancock CR, Han DH, Chen M, Terada S, Yasuda T, Wright DC, Holloszy JO 2008 High-fat diets cause insulin resistance despite an increase in muscle mitochondria. Proc Natl Acad SciUSA105:7815-7820 (Pubitemid 351872721)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.22
, pp. 7815-7820
-
-
Hancock, C.R.1
Han, D.-H.2
Chen, M.3
Terada, S.4
Yasuda, T.5
Wright, D.C.6
Holloszy, J.O.7
-
4
-
-
0030740621
-
Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in NIDDM
-
Simoneau JA, Kelley DE 1997 Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in NIDDM. J Appl Physiol 83:166-171 (Pubitemid 27304746)
-
(1997)
Journal of Applied Physiology
, vol.83
, Issue.1
, pp. 166-171
-
-
Simoneau, J.-A.1
Kelley, D.E.2
-
5
-
-
0036788293
-
Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes mellitus
-
Kelley D, He J, Menshikova EV, Ritov VB 2002 Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes mellitus. Diabetes 51:2944-2950
-
(2002)
Diabetes
, vol.51
, pp. 2944-2950
-
-
Kelley, D.1
He, J.2
Menshikova, E.V.3
Ritov, V.B.4
-
7
-
-
0033668021
-
Lipid oxidation is reduced in obese human skeletal muscle
-
Kim JY, Hickner RC, Cortright RL, Dohm GL, Houmard JA 2000 Lipid oxidation is reduced in obese human skeletal muscle. Am J Physiol Endocrinol Metab 279:E1039-E1044
-
(2000)
Am J Physiol Endocrinol Metab
, vol.279
-
-
Kim, J.Y.1
Hickner, R.C.2
Cortright, R.L.3
Dohm, G.L.4
Houmard, J.A.5
-
8
-
-
1642377274
-
Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
-
DOI 10.1056/NEJMoa031314
-
Petersen KF, Dufour S, Befroy D, Garcia R, Shulman GI 2004 Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 350:664-671 (Pubitemid 38364625)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.7
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
9
-
-
33847344733
-
Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle
-
DOI 10.2337/db06-0521
-
Ukropcova B, Sereda O, de Jonge L, Bogacka I, Nguyen T, Xie H, Bray GA, Smith SR 2007 Family history of diabetes links impaired substrate switching and reduced mitochondrial content in skeletal muscle. Diabetes 56:720-727 (Pubitemid 46348476)
-
(2007)
Diabetes
, vol.56
, Issue.3
, pp. 720-727
-
-
Ukropcova, B.1
Sereda, O.2
De, J.L.3
Bogacka, I.4
Nguyen, T.5
Xie, H.6
Bray, G.A.7
Smith, S.R.8
-
10
-
-
33845542745
-
Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
-
DOI 10.2337/db06-S002
-
Morino K, Petersen KF, Shulman GI 2006 Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction. Diabetes 55:S9-S15 (Pubitemid 44927027)
-
(2006)
Diabetes
, vol.55
, Issue.SUPPL. 2
-
-
Morino, K.1
Petersen, K.F.2
Shulman, G.I.3
-
11
-
-
58149389257
-
Muscle mitochondrial changes with aging and exercise
-
Lanza IR, Nair KS 2009 Muscle mitochondrial changes with aging and exercise. Am J Clin Nutr 89:467S-471S
-
(2009)
Am J Clin Nutr
, vol.89
-
-
Lanza, I.R.1
Nair, K.S.2
-
12
-
-
0037477855
-
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
-
DOI 10.1073/pnas.1032913100
-
Patti ME, Butte AJ, Crunkhorn S, Cusi K, Berria R, Kashyap S, Miyazaki Y, Kohane I, Costello M, Saccone R, Landaker EJ, Goldfine AB, Mun E, DeFronzo R, Finlayson J, Kahn CR, Mandarino LJ 2003 Coordinated reduction in genes of oxidative metabolism in humans with insulin resistance and diabetes: potential roles of PGC1 and NRF-1. Proc Natl Acad Sci USA 100:8466-8471 (Pubitemid 36842568)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.14
, pp. 8466-8471
-
-
Patti, M.E.1
Butte, A.J.2
Crunkhorn, S.3
Cusi, K.4
Berria, R.5
Kashyap, S.6
Miyazaki, Y.7
Kohane, I.8
Costello, M.9
Saccone, R.10
Landaker, E.J.11
Goldfine, A.B.12
Mun, E.13
DeFronzo, R.14
Finlayson, J.15
Kahn, C.R.16
Mandarino, L.J.17
-
13
-
-
34147175161
-
Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects
-
DOI 10.1210/jc.2006-2210
-
Heilbronn LK, Gan SK, Turner N, Campbell LV, Chisholm DJ 2007 Markers of mitochondrial biogenesis and metabolism are lower in overweight and obese insulin-resistant subjects. J Clin Endocrinol Metab 92:1467-1473 (Pubitemid 46556427)
-
(2007)
Journal of Clinical Endocrinology and Metabolism
, vol.92
, Issue.4
, pp. 1467-1473
-
-
Heilbronn, L.K.1
Seng, K.G.2
Turner, N.3
Campbell, L.V.4
Chisholm, D.J.5
-
14
-
-
12144275294
-
Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes
-
DOI 10.2337/diabetes.54.1.8
-
Ritov VB, Menshikova EV, He J, Ferrell RE, Goodpaster BH, Kelley DE 2005 Deficiency of subsarcolemmal mitochondria in obesity and type 2 diabetes. Diabetes 54:8-14 (Pubitemid 40105089)
-
(2005)
Diabetes
, vol.54
, Issue.1
, pp. 8-14
-
-
Ritov, V.B.1
Menshikova, E.V.2
He, J.3
Ferrell, R.E.4
Goodpaster, B.H.5
Kelley, D.E.6
-
15
-
-
33845514376
-
Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia
-
DOI 10.2337/db05-1230
-
Asmann YW, Stump CS, Short KR, Coenen-Schimke JM, Guo Z, Bigelow ML, Nair KS 2006 Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia. Diabetes 55:3309-3319 (Pubitemid 44923587)
-
(2006)
Diabetes
, vol.55
, Issue.12
, pp. 3309-3319
-
-
Asmann, Y.W.1
Stump, C.S.2
Short, K.R.3
Coenen-Schimke, J.M.4
Guo, Z.5
Bigelow, M.L.6
Nair, K.S.7
-
16
-
-
33646403717
-
Impact of exercise training on insulin sensitivity, physical fitness, and muscle oxidative capacity in first-degree relatives of type 2 diabetic patients
-
Østergard T, Andersen JL, Nyholm B, Lund S, Nair KS, Saltin B, Schmitz O 2006 Impact of exercise training on insulin sensitivity, physical fitness, and muscle oxidative capacity in first-degree relatives of type 2 diabetic patients. Am J Physiol Endocrinol Metab 290:E998-E1005
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Østergard, T.1
Andersen, J.L.2
Nyholm, B.3
Lund, S.4
Nair, K.S.5
Saltin, B.6
Schmitz, O.7
-
17
-
-
34547596186
-
Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes
-
DOI 10.2337/db07-0141
-
Toledo FG, Menshikova EV, Ritov VB, Azuma K, Radikova Z, DeLany J, Kelley DE 2007 Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes. Diabetes 56:2142-2147 (Pubitemid 47195831)
-
(2007)
Diabetes
, vol.56
, Issue.8
, pp. 2142-2147
-
-
Toledo, F.G.S.1
Menshikova, E.V.2
Ritov, V.B.3
Azuma, K.4
Radikova, Z.5
DeLany, J.6
Kelley, D.E.7
-
18
-
-
33747702159
-
Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women
-
DOI 10.1210/jc.2006-0002
-
Toledo FG, Watkins S, Kelley DE 2006 Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women. J Clin Endocrinol Metab 91: 3224-3227 (Pubitemid 44271780)
-
(2006)
Journal of Clinical Endocrinology and Metabolism
, vol.91
, Issue.8
, pp. 3224-3227
-
-
Toledo, F.G.S.1
Watkins, S.2
Kelley, D.E.3
-
19
-
-
0023913503
-
Some new, simple and efficient stereological methods and their use in pathological research and diagnosis
-
Gundersen HJ, Bendtsen TF, Korbo L, Marcussen N, Møller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sorensen FB, Vesterby A 1988 Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96:379-394
-
(1988)
APMIS
, vol.96
, pp. 379-394
-
-
Gundersen, H.J.1
Bendtsen, T.F.2
Korbo, L.3
Marcussen, N.4
Møller, A.5
Nielsen, K.6
Nyengaard, J.R.7
Pakkenberg, B.8
Sorensen, F.B.9
Vesterby, A.10
-
21
-
-
42449094965
-
Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content
-
Toledo FG, Menshikova EV, Azuma K, Radikova Z, Kelley CA, Ritov VB, Kelley DE 2008 Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content. Diabetes 57:987-994
-
(2008)
Diabetes
, vol.57
, pp. 987-994
-
-
Toledo, F.G.1
Menshikova, E.V.2
Azuma, K.3
Radikova, Z.4
Kelley, C.A.5
Ritov, V.B.6
Kelley, D.E.7
-
22
-
-
0022260872
-
Endurance training in humans: Aerobic capacity and structure of skeletal muscle
-
Hoppeler H, Howald H, Conley K, Lindstedt SL, Claassen H, Vock P, Weibel ER 1985 Endurance training in humans: aerobic capacity and structure of skeletal muscle. J Appl Physiol 59:320-327 (Pubitemid 15249855)
-
(1985)
Journal of Applied Physiology
, vol.59
, Issue.2
, pp. 320-327
-
-
Hoppeler, H.1
Howald, H.2
Conley, K.3
-
23
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
DOI 10.1126/science.1082889
-
Petersen KF, Befroy D, Dufour S, Dziura J, Ariyan C, Rothman DL, DiPietro L, Cline GW, Shulman GI 2003 Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science 300:1140-1142 (Pubitemid 36583097)
-
(2003)
Science
, vol.300
, Issue.5622
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
Dziura, J.4
Ariyan, C.5
Rothman, D.L.6
DiPietro, L.7
Cline, G.W.8
Shulman, G.I.9
-
24
-
-
34447576831
-
Skeletal muscle mitochondrial FAT/CD36 content and palmitate oxidation are not decreased in obese women
-
DOI 10.1152/ajpendo.00639.2006
-
Holloway GP, Thrush AB, Heigenhauser GJ, Tandon NN, Dyck DJ, Bonen A, Spriet LL 2007 Skeletal muscle mitochondrial FAT/CD36 content and palmitate oxidation are not decreased in obese women. Am J Physiol Endocrinol Metab 292:E1782-E1789 (Pubitemid 47084714)
-
(2007)
American Journal of Physiology - Endocrinology and Metabolism
, vol.292
, Issue.6
-
-
Holloway, G.P.1
Thrush, A.B.2
Heigenhauser, G.J.F.3
Tandon, N.N.4
Dyck, D.J.5
Bonen, A.6
Spriet, L.L.7
-
25
-
-
0032752951
-
Markers of capacity to utilize fatty acids in human skeletal muscle: Relation to insulin resistance and obesity and effects of weight loss
-
Simoneau JA, Veerkamp JH, Turcotte LP, Kelley DE 1999 Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss. FASEB J 13:2051-2060 (Pubitemid 29517635)
-
(1999)
FASEB Journal
, vol.13
, Issue.14
, pp. 2051-2060
-
-
Simoneau, J.-A.1
Veerkamp, J.H.2
Turcotte, L.P.3
Kelley, D.E.4
-
26
-
-
34249720640
-
Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes
-
DOI 10.2337/db06-0981
-
Mogensen M, Sahlin K, Fernström M, Glintborg D, Vind BF, Beck-Nielsen H, Hojlund K 2007 Mitochondrial respiration is decreased in skeletal muscle of patients with type 2 diabetes. Diabetes 56: 1592-1599 (Pubitemid 46842617)
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1592-1599
-
-
Mogensen, M.1
Sahlin, K.2
Fernstrom, M.3
Glintborg, D.4
Vind, B.F.5
Beck-Nielsen, H.6
Hojlund, K.7
-
27
-
-
0030958862
-
Ultra-high-resolution scanning electron microscopy of mitochondria and sarcoplasmic reticulum arrangement in human red, white, and intermediate muscle fibers
-
DOI 10.1002/(SICI)1097-0185(199706)248:2<214::AID-AR8>3.0.CO;2-S
-
Ogata T, Yamasaki Y 1997 Ultra-high-resolution scanning electron microscopy of mitochondria and sarcoplasmic reticulum arrangement in human red, white, and intermediate muscle fibers. Anat Rec 248:214-223 (Pubitemid 27246816)
-
(1997)
Anatomical Record
, vol.248
, Issue.2
, pp. 214-223
-
-
Ogata, T.1
Yamasaki, Y.2
-
28
-
-
0001926668
-
-
Pernow B., Saltin B., eds. New York: Plenum Press
-
Kiessling KH, Piehl K, Lundquist CG 1970 Effect of physical training on ultrastructural features in human skeletal muscle. In: Pernow B., Saltin B., eds. New York: Plenum Press; 97-101
-
(1970)
Effect of Physical Training on Ultrastructural Features in Human Skeletal Muscle
, pp. 97-101
-
-
Kiessling, K.H.1
Piehl, K.2
Lundquist, C.G.3
-
29
-
-
65249175787
-
Effect of hyperglycemia on mitochondrial respiration in type 2 diabetes
-
Rabol R, Højberg PM, Almdal T, Boushel R, Haugaard SB, Madsbad S, Dela F 2009 Effect of hyperglycemia on mitochondrial respiration in type 2 diabetes. J Clin Endocrinol Metab 94:1372-1378
-
(2009)
J Clin Endocrinol Metab
, vol.94
, pp. 1372-1378
-
-
Rabol, R.1
Højberg, P.M.2
Almdal, T.3
Boushel, R.4
Haugaard, S.B.5
Madsbad, S.6
Dela, F.7
-
30
-
-
21344444333
-
A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle
-
DOI 10.2337/diabetes.54.7.1926
-
Sparks LM, Xie H, Koza RA, Mynatt R, Hulver MW, Bray GA, Smith SR 2005 A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle. Diabetes 54:1926-1933 (Pubitemid 40911253)
-
(2005)
Diabetes
, vol.54
, Issue.7
, pp. 1926-1933
-
-
Sparks, L.M.1
Xie, H.2
Koza, R.A.3
Mynatt, R.4
Hulver, M.W.5
Bray, G.A.6
Smith, S.R.7
-
31
-
-
67650815430
-
Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
-
Anderson EJ, Lustig ME, Boyle KE, Woodlief TL, Kane DA, Lin CT, Price 3rd JW, Kang L, Rabinovitch PS, Szeto HH, Houmard JA, Cortright RN, Wasserman DH, Neufer PD 2009 Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans. J Clin Invest 119: 573-581
-
(2009)
J Clin Invest
, vol.119
, pp. 573-581
-
-
Anderson, E.J.1
Lustig, M.E.2
Boyle, K.E.3
Woodlief, T.L.4
Kane, D.A.5
Lin, C.T.6
Price III, J.W.7
Kang, L.8
Rabinovitch, P.S.9
Szeto, H.H.10
Houmard, J.A.11
Cortright, R.N.12
Wasserman, D.H.13
Neufer, P.D.14
-
32
-
-
33847730262
-
Effect of denervation on mitochondrially mediated apoptosis in skeletal muscle
-
DOI 10.1152/japplphysiol.00768.2006
-
Adhihetty PJ, O'Leary MF, Chabi B, Wicks KL, Hood DA 2007 Effect of denervation on mitochondrially mediated apoptosis in skeletal muscle. J Appl Physiol 102:1143-1151 (Pubitemid 46377042)
-
(2007)
Journal of Applied Physiology
, vol.102
, Issue.3
, pp. 1143-1151
-
-
Adhihetty, P.J.1
O'Leary, M.F.N.2
Chabi, B.3
Wicks, K.L.4
Hood, D.A.5
-
33
-
-
0018874511
-
Populations of rat skeletal muscle mitochondria after exercise and immobilization
-
Krieger DA, Tate CA, McMillin-Wood J, Booth FW 1980 Populations of rat skeletal muscle mitochondria after exercise and immobilization. J Appl Physiol 48:23-28 (Pubitemid 10143838)
-
(1980)
Journal of Applied Physiology Respiratory Environmental and Exercise Physiology
, vol.48
, Issue.1
, pp. 23-28
-
-
Krieger, D.A.1
Tate, C.A.2
McMillin-Wood, J.3
Booth, F.W.4
-
34
-
-
0037230261
-
Plasticity of skeletal muscle mitochondria: Structure and function
-
DOI 10.1097/00005768-200301000-00016
-
Hoppeler H, Fluck M 2003 Plasticity of skeletal muscle mitochondria: structure and function. Med Sci Sports Exerc 35:95-104 (Pubitemid 36084147)
-
(2003)
Medicine and Science in Sports and Exercise
, vol.35
, Issue.1
, pp. 95-104
-
-
Hoppeler, H.1
Flock, M.2
-
35
-
-
0025047553
-
Skeletal muscle metabolism is a major determinant of resting energy expenditure
-
Zurlo F, Larson K, Bogardus C, Ravussin E 1990 Skeletal muscle metabolism is a major determinant of resting energy expenditure. J Clin Invest 86:1423-1427 (Pubitemid 20372586)
-
(1990)
Journal of Clinical Investigation
, vol.86
, Issue.5
, pp. 1423-1427
-
-
Zurlo, F.1
Larson, K.2
Bogardus, C.3
Ravussin, E.4
-
36
-
-
0034076660
-
Fuel selection in human skeletal muscle in insulin resistance: A reexamination
-
Kelley DE, Mandarino LJ 2000 Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes 49:677-683 (Pubitemid 30339979)
-
(2000)
Diabetes
, vol.49
, Issue.5
, pp. 677-683
-
-
Kelley, D.E.1
Mandarino, L.J.2
-
37
-
-
0033400310
-
Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
-
Kelley DE, Goodpaster B, Wing RR, Simoneau JA 1999 Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am J Physiol 277:E1130-E1141 (Pubitemid 30046009)
-
(1999)
American Journal of Physiology - Endocrinology and Metabolism
, vol.277
, Issue.6
-
-
Kelley, D.E.1
Goodpaster, B.2
Wing, R.R.3
Simoneau, J.-A.4
-
38
-
-
0027946529
-
Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus
-
Kelley DE, Simoneau JA 1994 Impaired free fatty acid utilization by skeletal muscle in non-insulin-dependent diabetes mellitus. J Clin Invest 94:2349-2356
-
(1994)
J Clin Invest
, vol.94
, pp. 2349-2356
-
-
Kelley, D.E.1
Simoneau, J.A.2
-
40
-
-
0033837861
-
Lipid metabolism during endurance exercise
-
Horowitz JF, Klein S 2000 Lipid metabolism during endurance exercise. Am J Clin Nutr 72:558S-563S
-
(2000)
Am J Clin Nutr
, vol.72
-
-
Horowitz, J.F.1
Klein, S.2
-
41
-
-
0020072748
-
Significance of skeletal muscle oxidative enzyme enhancement with endurance training
-
Gollnick PD, Saltin B 1982 Significance of skeletal muscle oxidative enzyme enhancement with endurance training. Clin Physiol 2:1-12 (Pubitemid 12146273)
-
(1982)
Clinical Physiology
, vol.2
, Issue.1
, pp. 1-12
-
-
Gollnick, P.D.1
Saltin, B.2
|