Tacrolimus as rescue therapy for adult-onset refractory minimal change nephrotic syndrome with reversible acute renal failure

Nephrology Dialysis Transplantation

Volumn 28, Issue 9, 2013, Pages 2306-2312

  Li, Xiayu ^a   Xu, Nan ^a   Li, Heng ^a   Han, Fei ^a   Wang, Rending ^a   He, Qiang ^a   He, Xuelin ^a   Chen, Jianghua ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Acute renal failure; Minimal change nephrotic syndrome; Tacrolimus

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; STEROID; TACROLIMUS;

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; BACTERIAL PNEUMONIA; CLINICAL ARTICLE; CLINICAL TRIAL; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; ESTIMATED GLOMERULAR FILTRATION RATE; FEMALE; FOLLOW UP; GASTROINTESTINAL SYMPTOM; HUMAN; HYPERTENSION; INFECTION; LIVER TOXICITY; MALE; MINIMAL CHANGE NEPHROTIC SYNDROME; NAUSEA AND VOMITING; NEPHROTIC SYNDROME; NEPHROTOXICITY; ONSET AGE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RELAPSE; REMISSION; RENAL SYSTEM PARAMETERS; SIDE EFFECT; TREATMENT FAILURE; URINARY TRACT INFECTION;

ACUTE RENAL FAILURE; MINIMAL CHANGE NEPHROTIC SYNDROME; TACROLIMUS;

ACUTE KIDNEY INJURY; ADULT; AGE OF ONSET; AGED; DRUG RESISTANCE; FEMALE; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY FUNCTION TESTS; MALE; MIDDLE AGED; NEPHROTIC SYNDROME; PROGNOSIS; PROSPECTIVE STUDIES; RISK FACTORS; STEROIDS; TACROLIMUS; YOUNG ADULT;

EID: 84884510265     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gft207     Document Type: Article

References (32)

1. Waldman M, Crew RJ, Valeri A et al. Adult minimal-change disease: clinical characteristics, treatment, and outcomes. Clin J Am Soc Nephrol 2007; 2: 445-453
2. Kirpekar R, Yorgin PD, Tune BM et al. Clinicopathologic correlates predict the outcome in children with steroid-resistant idiopathic nephrotic syndrome treated with pulse methylprednisolone therapy. Am J Kidney Dis 2002; 39: 1143-1152
3. Plank C, Kalb V, Hinkes B et al. Cyclosporin A is superior to cyclophosphamide in children with steroid-resistant nephrotic syndrome-a randomized controlled multicentre trial by the Arbeitsgemeinschaft für Pädiatrische Nephrologie. Pediatr Nephrol 2008; 23: 1483-1493
4. Mendizabal S, Zamora I, Berbel O et al. Mycophenolate mofetil in steroid/cyclosporine-dependent/resistant nephrotic syndrome. Pediatr Nephrol 2005; 20: 914-919
5. Gulati A, Sinha A, Jordan SC et al. Efficacy and safety of treatment with rituximab for difficult steroid-resistant and -dependent nephrotic syndrome: multicentric report. Clin J Am Soc Nephrol 2010; 5: 2207-2212
6. Jennette JC, Falk RJ. Adult minimal change glomerulopathy with acute renal failure. Am J Kidney Dis 1990; 16: 432-437
7. Chen CL, Fang HC, Chou KJ et al. Increased endothelin 1 expression in adult-onset minimal change nephropathy with acute renal failure. Am J Kidney Dis 2005; 45: 818-825
8. Kidney Disease: Improving Global Outcomes (KDIGO) Glomerulonephrits Work Group. KDIGO clinical practice guideline for glomerulonephrits. Kidney Int Suppl 2012; 2: 172-185
9. Budde K, Fritsche L, Neumayer HH. Differing proteinuria control with cyclosporine and tacrolimus. Lancet 1997; 349: 330
10. Chamienia A, Biedunkiewicz B, Krol E et al. One-year observation of kidney allograft recipients converted from cyclosporine microemulsion to tacrolimus. Transplant Proc 2006; 38: 81-85
11. Choudhry S, Bagga A, Hari P et al. Efficacy and safety of tacrolimus versus cyclosporine in children with steroid-resistant nephrotic syndrome: a randomized controlled trial. Am J Kidney Dis 2009; 53: 760-769
12. Gulati S, Prasad N, Sharma RK et al. Tacrolimus: a new therapy for steroid-resistant nephrotic syndrome in children. Nephrol Dial Transplant 2008; 23: 910-913
13. Roberti I, Vyas S. Long-term outcome of children with steroidresistant nephrotic syndrome treated with tacrolimus. Pediatr Nephrol 2010; 25: 1117-1124
14. Butani L, Ramsamooj R. Experience with tacrolimus in children with steroid-resistant nephrotic syndrome. Pediatr Nephrol 2009; 24: 1517-1523
15. Li H, Shi X, Shen H et al. Tacrolimus versus intravenous pulse cyclophosphamide therapy in Chinese adults with steroid-resistant idiopathic minimal change nephropathy: a multicenter, openlabel, nonrandomized cohort trial. Clin Ther 2012; 34: 1112-1120
16. Li X, Li H, Ye H et al. Tacrolimus therapy in adults with steroidand cyclophosphamide-resistant nephrotic syndrome and normal or mildly reduced GFR. Am J Kidney Dis 2009; 54: 51-58
17. Li X, Li H, Chen J et al. Tacrolimus as a steroid-sparing agent for adults with steroid-dependent minimal change nephrotic syndrome. Nephrol Dial Transplant 2008; 23: 1919-1925
18. Li X, Lv R, He Q et al. Early initiation of therapy tacrolimus or cyclophosphamide for idiopathic membranous nephropathy with severe proteinuria. J Nephrol 2008; 21: 584-591
19. Faul C, Donnelly M, Merscher-Gomez S et al. The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A. Nat Med 2008; 14: 931-938
20. Peters DH, Fitton A, Plosker GL et al. A review of its pharmacology, and therapeutic potential in hepatic and renal transplantation. Drugs 1993; 46: 746-749
21. Agarwal N, Phadke KD, Garg I et al. Acute renal failure in children with idiopathic nephrotic syndrome. Pediatr Nephrol 2003; 18: 1289-1292
22. Vande Walle J, Mauel R, Raes A et al. ARF in children with minimal change nephrotic syndrome may be related to functional changes of the glomerular basal membrane. Am J Kidney Dis 2004; 43: 399-404
23. Chen T, Lv Y, Lin F et al. Acute kidney injury in adult idiopathic nephrotic syndrome. Ren Fail 2011; 33: 144-149
24. Stellato T, Cappelleri A, Farina M et al. Severe reversible acute renal failure in idiopathic nephrotic syndrome. J Nephrol 2010; 23: 717-724
25. James MT, Hemmelgam BR, Wiebe N et al. Glomerular filtration rate, proteinuria, and the incidence and consequences of acute kidney injury: a cohort study. Lancet 2010; 18: 2096-2103
26. Ekberg H, Tedesco-Silva H, Demirbas A et al. Reduced exposure to calcineurin inhibitors in renal transplantation. N Engl J Med 2007; 357: 2562-2575
27. Falkiewicz K, Kaninska D, Nahaczewska W et al. Renal function and tubular phosphate handling in long-term cyclosporine-and tacrolimus-based immunosuppression in kidney transplantation. Transplant Proc 2006; 38: 119-122
28. Morgan C, Sis B, Pinsk M et al. Renal interstitial fibrosis in children treated with FK506 for nephrotic syndrome. Nephrol Dial Transplant 2011; 26: 2860-2865
29. Segarra A, Vila J, Pou L et al. Combined therapy of tacrolimus and corticosteroids in cyclosporin-resistant or-dependent idiopathic focal glomerulosclerosis: a preliminary uncontrolled study with prospective follow-up. Nephrol Dial Transplant 2002; 17: 655-662
30. Roos-van Groningen MC, Scholten EM, Lelieveld PM et al. Molecular comparison of calcineurin inhibitor-induced fibrogenic responses in protocol renal transplant biopsies. J Am Soc Nephrol 2006; 17: 881-888
31. Naesens M, Kuypers DR, Sarwal M. Calcineurin inhibitor nephrotoxicity. Clin J Am Soc Nephrol 2009; 4: 481-508
32. Jacobson PA, Schladt D, Israni A et al. Genetic and clinical determinants of early, acute calcineurin inhibitor-related nephrotoxicity: results from a kidney transplant consortium. Transplantation 2012; 93: 624-631