-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987-996.
-
(2005)
N Engl J Med
, vol.352
, Issue.10
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
2
-
-
0035863293
-
Randomized trial of porcarbazine, lomustine, and vincristine in the adjuvant treatment of high-grade astrocytoma: A medical research council trial
-
Thomas D, Brada M, Stenning S. Randomized trial of porcarbazine, lomustine, and vincristine in the adjuvant treatment of high-grade astrocytoma: A medical research council trial. J Clin Oncol. 2001;19(2):509-518.
-
(2001)
J Clin Oncol
, vol.19
, Issue.2
, pp. 509-518
-
-
Thomas, D.1
Brada, M.2
Stenning, S.3
-
3
-
-
0030762796
-
Preirradiation paclitaxel in glioblastoma multiforme: Efficacy, pharmacology, and drug interactions
-
Fetell MR, Grossman SA, Fisher JD, et al. Preirradiation paclitaxel in glioblastoma multiforme: efficacy, pharmacology, and drug interactions. New Approaches to Brain Tumor Therapy Central Nervous System Consortium. J Clin Oncol. 1997;15(9):3121-3128.
-
(1997)
J Clin Oncol
, vol.15
, Issue.9
, pp. 3121-3128
-
-
Fetell, M.R.1
Grossman, S.A.2
Fisher, J.D.3
-
4
-
-
77956517283
-
In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma
-
Mir SE, de Witt Hamer PC, Krawczyk PM, et al. In silico analysis of kinase expression identifies WEE1 as a gatekeeper against mitotic catastrophe in glioblastoma. Cancer Cell. 2010;18(3):244-257.
-
(2010)
Cancer Cell
, vol.18
, Issue.3
, pp. 244-257
-
-
Mir, S.E.1
De Witt Hamer, P.C.2
Krawczyk, P.M.3
-
5
-
-
4544254677
-
A field guide to the Mps1 family of protein kinases
-
Fisk HA, Mattison CP, Winey M. A field guide to the Mps1 family of protein kinases. Cell Cycle. 2004;3(4):439-442.
-
(2004)
Cell Cycle
, vol.3
, Issue.4
, pp. 439-442
-
-
Fisk, H.A.1
Mattison, C.P.2
Winey, M.3
-
6
-
-
34247333444
-
The spindle-assembly checkpoint in space and time
-
Musacchio A and Salmon ED. The spindle-assembly checkpoint in space and time. Nat Rev Mol Cell Biol. 2007;8(5):379-393.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.5
, pp. 379-393
-
-
Musacchio, A.1
Salmon, E.D.2
-
7
-
-
45349103038
-
Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores
-
Tighe A, Staples O, Taylor S. Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores. J Cell Biol. 2008;181(6):893-901.
-
(2008)
J Cell Biol
, vol.181
, Issue.6
, pp. 893-901
-
-
Tighe, A.1
Staples, O.2
Taylor, S.3
-
8
-
-
77954706607
-
Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling
-
Maciejowski J, George KA, Terret ME, et al. Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling. J Cell Biol. 2010;190(1):89-100.
-
(2010)
J Cell Biol
, vol.190
, Issue.1
, pp. 89-100
-
-
Maciejowski, J.1
George, K.A.2
Terret, M.E.3
-
9
-
-
36849091065
-
Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism
-
Maure JF, Kitamura E, Tanaka TU. Mps1 kinase promotes sister-kinetochore bi-orientation by a tension-dependent mechanism. Curr Biol. 2007;17(24):2175- 2182.
-
(2007)
Curr Biol
, vol.17
, Issue.24
, pp. 2175-2182
-
-
Maure, J.F.1
Kitamura, E.2
Tanaka, T.U.3
-
10
-
-
48749132272
-
Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes
-
Jelluma N, Brenkman AB, McLeod I, et al. Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomes. PLoS One. 2008;3(6):e2415.
-
(2008)
PLoS One
, vol.3
, Issue.6
-
-
Jelluma, N.1
Brenkman, A.B.2
McLeod, I.3
-
11
-
-
38649133379
-
Mps1 phosphorylates borealin to control aurora B activity and chromosome alignment
-
Jelluma N, Brenkman AB, van den Broek NJ, et al. Mps1 phosphorylates borealin to control aurora B activity and chromosome alignment. Cell. 2008;132(2):233-246.
-
(2008)
Cell
, vol.132
, Issue.2
, pp. 233-246
-
-
Jelluma, N.1
Brenkman, A.B.2
Van Den Broek, N.J.3
-
12
-
-
77954698217
-
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
-
Santaguida S, Tighe A, D'Alise AM, Taylor SS, Musacchio A. Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. J Cell Biol. 2010;190(1):73-87.
-
(2010)
J Cell Biol
, vol.190
, Issue.1
, pp. 73-87
-
-
Santaguida, S.1
Tighe, A.2
D'alise, A.M.3
Taylor, S.S.4
Musacchio, A.5
-
13
-
-
66349136840
-
TTK/hMps1 mediates the p53-dependent postmitotic checkpoint by phosphorylating p53 at Thr18
-
Huang YF, Chang MD, Shieh SY. TTK/hMps1 mediates the p53-dependent postmitotic checkpoint by phosphorylating p53 at Thr18. Mol Cell Biol. 2009;29(11):2935-2944.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.11
, pp. 2935-2944
-
-
Huang, Y.F.1
Chang, M.D.2
Shieh, S.Y.3
-
14
-
-
62249140224
-
The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1
-
Yeh YH, Huang YF, Lin TY, Shieh SY. The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1. Oncogene. 2009;28(10):1366-1378.
-
(2009)
Oncogene
, vol.28
, Issue.10
, pp. 1366-1378
-
-
Yeh, Y.H.1
Huang, Y.F.2
Lin, T.Y.3
Shieh, S.Y.4
-
15
-
-
34547108860
-
Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling
-
Zhu S, Wang W, Clarke DC, Liu X. Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling. J Biol Chem. 2007;282(25):18327-18338.
-
(2007)
J Biol Chem
, vol.282
, Issue.25
, pp. 18327-18338
-
-
Zhu, S.1
Wang, W.2
Clarke, D.C.3
Liu, X.4
-
16
-
-
0036211372
-
Chromosome instability in malignant astrocytic tumors detected by fluorescence in situ hybridization
-
Nishizaki T, Harada K, Kubota H, et al. Chromosome instability in malignant astrocytic tumors detected by fluorescence in situ hybridization. J Neurooncol. 2002;56(2):159-165.
-
(2002)
J Neurooncol
, vol.56
, Issue.2
, pp. 159-165
-
-
Nishizaki, T.1
Harada, K.2
Kubota, H.3
-
17
-
-
33846979444
-
Aurora B expression correlates with aggressive behaviour in glioblastoma multiforme
-
Zeng WF, Navaratne K, Prayson RA, Weil RJ. Aurora B expression correlates with aggressive behaviour in glioblastoma multiforme. J Clin Pathol. 2007;60(2):218-221.
-
(2007)
J Clin Pathol
, vol.60
, Issue.2
, pp. 218-221
-
-
Zeng, W.F.1
Navaratne, K.2
Prayson, R.A.3
Weil, R.J.4
-
18
-
-
0032542364
-
Genetic instabilities in human cancers
-
Lengauer C, Kinzler KW and Vogelstein B. Genetic instabilities in human cancers. Nature. 1998;396(6712):643-649.
-
(1998)
Nature
, vol.396
, Issue.6712
, pp. 643-649
-
-
Lengauer, C.1
Kinzler, K.W.2
Vogelstein, B.3
-
19
-
-
0025824979
-
Mechanism of inhibition of cell proliferation by Vinca alkaloids
-
Jordan MA, Thrower D, Wilson L. Mechanism of inhibition of cell proliferation by Vinca alkaloids. Cancer Res. 1991;51(8):2212-2222.
-
(1991)
Cancer Res
, vol.51
, Issue.8
, pp. 2212-2222
-
-
Jordan, M.A.1
Thrower, D.2
Wilson, L.3
-
20
-
-
0026643589
-
Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles
-
Jordan MA, Thrower D, Wilson L. Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis. J Cell Sci. 1992;102(Pt 3):401-416.
-
(1992)
Implications for the Role of Microtubule Dynamics in Mitosis. J Cell Sci
, vol.102
, Issue.PART 3
, pp. 401-416
-
-
Jordan, M.A.1
Thrower, D.2
Wilson, L.3
-
21
-
-
0027360552
-
Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations
-
Jordan MA, Toso RJ, Thrower D, Wilson L. Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations. Proc Natl Acad Sci U S A. 1993;90(20):9552-9556.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.20
, pp. 9552-9556
-
-
Jordan, M.A.1
Toso, R.J.2
Thrower, D.3
Wilson, L.4
-
22
-
-
0037303101
-
Paclitaxel resistance: Molecular mechanisms and pharmacologic manipulation
-
Yusuf RZ, Duan Z, Lamendola DE, Penson RT, Seiden MV. Paclitaxel resistance: molecular mechanisms and pharmacologic manipulation. Curr Cancer Drug Targets. 2003;3(1):1-19.
-
(2003)
Curr Cancer Drug Targets
, vol.3
, Issue.1
, pp. 1-19
-
-
Yusuf, R.Z.1
Duan, Z.2
Lamendola, D.E.3
Penson, R.T.4
Seiden, M.V.5
-
23
-
-
0035949576
-
Resistance to taxol in lung cancer cells associated with increased microtubule dynamics
-
Goncalves A, Braguer D, Kamath K, et al. Resistance to taxol in lung cancer cells associated with increased microtubule dynamics. Proc Natl Acad Sci U S A. 2001;98(20):11737-11742.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.20
, pp. 11737-11742
-
-
Goncalves, A.1
Braguer, D.2
Kamath, K.3
-
24
-
-
78650322902
-
Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase
-
Colombo R, Caldarelli M, Mennecozzi M, et al. Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase. Cancer Res. 2010;70(24):10255-10264.
-
(2010)
Cancer Res
, vol.70
, Issue.24
, pp. 10255-10264
-
-
Colombo, R.1
Caldarelli, M.2
Mennecozzi, M.3
-
25
-
-
73149101630
-
Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells
-
Janssen A, Kops GJ, Medema RH. Elevating the frequency of chromosome mis-segregation as a strategy to kill tumor cells. Proc Natl Acad Sci U S A. 2009;106(45):19108-19113.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.45
, pp. 19108-19113
-
-
Janssen, A.1
Kops, G.J.2
Medema, R.H.3
-
26
-
-
77951299152
-
Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function
-
Kwiatkowski N, Jelluma N, Filippakopoulos P, et al. Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nat Chem Biol. 2010;6(5):359-368.
-
(2010)
Nat Chem Biol
, vol.6
, Issue.5
, pp. 359-368
-
-
Kwiatkowski, N.1
Jelluma, N.2
Filippakopoulos, P.3
-
27
-
-
20144381969
-
A small-molecule inhibitor of Mps1 blocks the spindle-checkpoint response to a lack of tension on mitotic chromosomes
-
Dorer RK, Zhong S, Tallarico JA, et al. A small-molecule inhibitor of Mps1 blocks the spindle-checkpoint response to a lack of tension on mitotic chromosomes. Curr Biol. 2005;15(11):1070-1076.
-
(2005)
Curr Biol
, vol.15
, Issue.11
, pp. 1070-1076
-
-
Dorer, R.K.1
Zhong, S.2
Tallarico, J.A.3
-
28
-
-
33645772227
-
Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
-
Sun L, Hui AM, Su Q, et al. Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell. 2006;9(4):287-300.
-
(2006)
Cancer Cell
, vol.9
, Issue.4
, pp. 287-300
-
-
Sun, L.1
Hui, A.M.2
Su, Q.3
-
29
-
-
77954715434
-
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex
-
Hewitt L, Tighe A, Santaguida S, et al. Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex. J Cell Biol. 2010;190(1):25-34.
-
(2010)
J Cell Biol
, vol.190
, Issue.1
, pp. 25-34
-
-
Hewitt, L.1
Tighe, A.2
Santaguida, S.3
-
30
-
-
77954748535
-
A chemical tool box defines mitotic and interphase roles for Mps1 kinase
-
Lan W, Cleveland DW. A chemical tool box defines mitotic and interphase roles for Mps1 kinase. J Cell Biol. 2010;190(1):21-24.
-
(2010)
J Cell Biol
, vol.190
, Issue.1
, pp. 21-24
-
-
Lan, W.1
Cleveland, D.W.2
-
31
-
-
4644313275
-
Gene expression profiling of gliomas strongly predicts survival
-
Freije WA, Castro-Vargas FE, Fang Z, et al. Gene expression profiling of gliomas strongly predicts survival. Cancer Res. 2004;64(18):6503-6510.
-
(2004)
Cancer Res
, vol.64
, Issue.18
, pp. 6503-6510
-
-
Freije, W.A.1
Castro-Vargas, F.E.2
Fang, Z.3
-
32
-
-
25444448993
-
Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas
-
Bredel M, Bredel C, Juric D, et al. Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas. Cancer Res. 2005;65(19):8679-8689.
-
(2005)
Cancer Res
, vol.65
, Issue.19
, pp. 8679-8689
-
-
Bredel, M.1
Bredel, C.2
Juric, D.3
-
33
-
-
84884489400
-
-
National Cancer Institute. 2005. REMBRANDT Home Page.. Accessed May 2, 2013.
-
National Cancer Institute. 2005. REMBRANDT Home Page. http://rembrandt.nci.nih.gov. Accessed May 2, 2013.
-
-
-
-
34
-
-
0345166853
-
Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression
-
Fisk HA, Mattison CP, Winey M. Human Mps1 protein kinase is required for centrosome duplication and normal mitotic progression. Proc Natl Acad Sci U S A. 2003;100(25):14875-14880.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.25
, pp. 14875-14880
-
-
Fisk, H.A.1
Mattison, C.P.2
Winey, M.3
-
35
-
-
63849225752
-
Human glioblastoma-derived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors
-
Wakimoto H, Kesari S, Farrell CJ, et al. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res. 2009;69(8): 3472-3481.
-
(2009)
Cancer Res
, vol.69
, Issue.8
, pp. 3472-3481
-
-
Wakimoto, H.1
Kesari, S.2
Farrell, C.J.3
-
36
-
-
2942567685
-
Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint
-
Kops GJ, Foltz DR, Cleveland DW. Lethality to human cancer cells through massive chromosome loss by inhibition of the mitotic checkpoint. Proc Natl Acad Sci U S A. 2004;101(23):8699-8704.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.23
, pp. 8699-8704
-
-
Kops, G.J.1
Foltz, D.R.2
Cleveland, D.W.3
-
37
-
-
1842533070
-
Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells
-
Michel L, Diaz-Rodriguez E, Narayan G, et al. Complete loss of the tumor suppressor MAD2 causes premature cyclin B degradation and mitotic failure in human somatic cells. Proc Natl Acad Sci U S A. 2004;101(13):4459-4464.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.13
, pp. 4459-4464
-
-
Michel, L.1
Diaz-Rodriguez, E.2
Narayan, G.3
-
38
-
-
44849106825
-
TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells
-
Kim M, Liao J, Dowling ML, et al. TRAIL inactivates the mitotic checkpoint and potentiates death induced by microtubule-targeting agents in human cancer cells. Cancer Res. 2008;68(9):3440-3449.
-
(2008)
Cancer Res
, vol.68
, Issue.9
, pp. 3440-3449
-
-
Kim, M.1
Liao, J.2
Dowling, M.L.3
-
39
-
-
4444245218
-
Inactivation of the mitotic checkpoint as a determinant of the efficacy of microtubule-targeted drugs in killing human cancer cells
-
Lee EA, Keutmann MK, Dowling ML, et al. Inactivation of the mitotic checkpoint as a determinant of the efficacy of microtubule-targeted drugs in killing human cancer cells. Mol Cancer Ther. 2004;3(6):661-669.
-
(2004)
Mol Cancer Ther
, vol.3
, Issue.6
, pp. 661-669
-
-
Lee, E.A.1
Keutmann, M.K.2
Dowling, M.L.3
-
40
-
-
0031756784
-
PCV chemotherapy for recurrent oligodendrogliomas and oligoastrocytomas
-
Soffietti R, Ruda R, Bradac GB, Schiffer D. PCV chemotherapy for recurrent oligodendrogliomas and oligoastrocytomas. Neurosurgery. 1998;43(5):1066-1073.
-
(1998)
Neurosurgery
, vol.43
, Issue.5
, pp. 1066-1073
-
-
Soffietti, R.1
Ruda, R.2
Bradac, G.B.3
Schiffer, D.4
-
41
-
-
68049083711
-
Combined radio-and chemotherapy of brain tumours in adult patients
-
Nieder C, Mehta MP, Jalali R. Combined radio-and chemotherapy of brain tumours in adult patients. Clin Oncol (R Coll Radiol). 2009;21(7):515-524.
-
(2009)
Clin Oncol (R Coll Radiol)
, vol.21
, Issue.7
, pp. 515-524
-
-
Nieder, C.1
Mehta, M.P.2
Jalali, R.3
-
42
-
-
77955071987
-
Vincristine in high-grade glioma
-
Aydin B, Patil M, Bekele N, Wolff JE. Vincristine in high-grade glioma. Anticancer Res. 2010;30(6):2303-2310.
-
(2010)
Anticancer Res
, vol.30
, Issue.6
, pp. 2303-2310
-
-
Aydin, B.1
Patil, M.2
Bekele, N.3
Wolff, J.E.4
-
43
-
-
71549126830
-
Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology
-
Gravendeel LA, Kouwenhoven MC, Gevaert O, et al. Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology. Cancer Res. 2009;69(23):9065-72. Stroke
-
(2009)
Cancer Res
, vol.69
, Issue.23
, pp. 9065-9072
-
-
Gravendeel, L.A.1
Kouwenhoven, M.C.2
Gevaert, O.3
|