Antidiabetic effect of total flavonoids from Sanguis draxonis in type 2 diabetic rats

Journal of Ethnopharmacology

Volumn 149, Issue 3, 2013, Pages 729-736

  Chen, Fufeng ^a   Xiong, Hui ^a   Wang, Jianxia ^a   Ding, Xin ^a   Shu, Guangwen ^a   Mei, Zhinan ^a  

^a SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES   (China)

Author keywords

Dyslipidemia; Flavonoids; Inflammation; Oxidative stress; Type 2 Diabetic mellitus

Indexed keywords

ANTIDIABETIC AGENT; C REACTIVE PROTEIN; FATTY ACID; FLAVONOID; GLUCOSE; GLUTATHIONE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONALDEHYDE; METFORMIN; RESIN; SANGUIS DRAXONIS FLAVONOID; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRACAENA; DYSLIPIDEMIA; FATTY ACID BLOOD LEVEL; GLUCOSE BLOOD LEVEL; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; LIPID BLOOD LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; RAT; RISK FACTOR; STEATOSIS; TRIACYLGLYCEROL BLOOD LEVEL;

DRACAENA COCHINCHINENSIS; RATTUS;

C-REACTIVE PROTEIN; CRP; D. COCHINCHINENSIS; DRACAENA COCHINCHINENSIS (LOUR.) S. C. CHEN; DYSLIPIDEMIA; ELISA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FFA; FLAVONOIDS; FREE FATTY ACIDS; GLUTATHIONE; GSH; HDL-C; HE; HEMATOXYLIN-EOSIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; IL-6; INFLAMMATION; INSULIN RESISTANCE; INSULIN TOLERANCE TEST; INTERLEUKIN-6; IR; ITT; LDL-C; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MALONDIALDEHYDE; MDA; OGTT; ORAL GLUCOSE TOLERANCE TEST; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; ROS; SANGUIS DRAXONIS; SD; SDF; SOD; STREPTOZOTOCIN; STZ; SUPEROXIDE DISMUTASE; T1DM; T2DM; TC; TG; TNF-Α; TOTAL CHOLESTEROL; TOTAL FLAVONOIDS FROM SD; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA; TYPE 1 DIABETES MELLITUS; TYPE 2 DIABETES MELLITUS; TYPE 2 DIABETIC MELLITUS;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DRACAENA; DRUGS, CHINESE HERBAL; FLAVONOIDS; GLUCOSE TOLERANCE TEST; HYPOGLYCEMIC AGENTS; INSULIN; LIPIDS; LIVER; MALE; PANCREAS; RATS; RATS, SPRAGUE-DAWLEY; RESINS, PLANT; STREPTOZOCIN; WOOD;

EID: 84884411980     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.07.035     Document Type: Article

References (40)

1. M. Balasubashini, R. Rukkumani, P. Viswanathan, and V.P. Menon Ferulic acid alleviates lipid peroxidation in diabetic rats Phytotherapy Research 18 2004 310 314
2. P. Bansal, P. Paul, J. Mudgal, P. G. Nayak, S. Thomas Pannakal, K.I. Priyadarsini, and M.K. Unnikrishnan Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoid rich fraction of Pilea microphylla (L.) in high fat diet/streptozotocin-induced diabetes in mice Experimental and Toxicologic Pathology 6 2012
3. A.G. Bertoni, W.G. Hundley, M.W. Massing, D.E. Bonds, G.L. Burke, and D.C. Goff Heart failure prevalence, incidence, and mortality in the elderly with diabetes Diabetes Care 27 2004 699 703
4. M. Bosma, S. Kersten, M.K.C. Hesselink, and P. Schrauwen Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity Progress in Lipid Research 51 2012 36 49
5. M.J. Chapman, and A.C. Sposito Hypertension and dyslipidaemia in obesity and insulin resistance: pathophysiology, impact on atherosclerotic disease and pharmacotherapy Pharmacology & Therapeutics 117 2008 354 373
6. H.-H. Chen, C.-C. Sun, M.-P. Tseng, and C.-J. Hsu A patch test study of 27 crude drugs commonly used in Chinese topical medicaments Contact Dermatitis 49 2003 8 14
7. E. China Pharmacopoeia Committee Pharmacopoeia of the People's Republic of China, the first division of 2005 edition 2005 China Chemical Industry Press Beijing 291 292
8. T. Cvetković, B. Mitić, G. Lazarević, P. Vlahović, S. Antić, and V. Stefanović Oxidative stress parameters as possible urine markers in patients with diabetic nephropathy Journal of Diabetes and its Complications 23 2009 337 342
9. C. De Luca, and J.M. Olefsky Inflammation and insulin resistance FEBS Letters 582 2008 97 105
10. L.L. Fan, P.F. Tu, J.X. He, H.B. Chen, and S.Q. Cai Microscopical study of original plant of Chinese drug "Dragon's Blood" Dracaena cochinchinensis and distribution and constituents detection of its resin China Journal of Chinese Materia Medica 10 2008 003
11. A.G. González, F. León, J.C. Hernández, J.I. Padrón, L. Sánchez-Pinto, and J.B. Barrera Flavans of dragon's blood from Dracaena draco and Dracaena tamaranae Biochemical Systematics and Ecology 32 2004 179 184
12. Jie Huang, Gao Hui, Xie Peide, and Lu Minyi The determination of Loureirin B in Resina Draconis by high-performance liquid chromatography Chinese Journal of Pharmaceutical Analysis 16 4 1996 234 236
13. Zhenqing Hou, Zhang Zhenxi, Zhang Chuanxin, and Huang Mei Use of natural plant exudates (Sanguis draxonis) for sustained oral insulin delivery with dramatic reduction of glycemic effects in diabetic rats Journal of Controlled Release 97 2004 467 475
14. Z. Hou, Z. Zhang, and H. Wu Effect of Sanguis draxonis (a Chinese traditional herb) on the formation of insulin resistance in rats Diabetes Research and Clinical Practice 68 2005 3 11
15. K. Indulekha, R.M. Anjana, J. Surendar, and V. Mohan Association of visceral and subcutaneous fat with glucose intolerance, insulin resistance, adipocytokines and inflammatory markers in Asian Indians (CURES-113) Clinical Biochemistry 44 2011 281 287
16. P. Kovacs, and M. Stumvoll Fatty acids and insulin resistance in muscle and liver Best Practice & Research Clinical Endocrinology & Metabolism 19 2005 625 635
17. Z. Lian, Y. Li, J. Gao, K. Qu, J. Li, L. Hao, S. Wu, and H. Zhu A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells Lipids Health Disease 10 2011 67
18. K. Likhitwitayawuid, K. Sawasdee, and K. Kirtikara Flavonoids and stilbenoids with COX-1 and COX-2 inhibitory activity from Dracaena loureiri Planta Medica 68 2002 841 843
19. K. Matsumoto, Y. Sera, Y. Abe, Y. Ueki, T. Tominaga, and S. Miyake Inflammation and insulin resistance are independently related to all-cause of death and cardiovascular events in Japanese patients with type 2 diabetes mellitus Atherosclerosis 169 2003 317 321
20. M. Mishra, H. Kumar, S. Bajpai, R.K. Singh, and K. Tripathi Level of serum IL-12 and its correlation with endothelial dysfunction, insulin resistance, proinflammatory cytokines and lipid profile in newly diagnosed type 2 diabetes Diabetes Research and Clinical Practice 94 2011 255 261
21. S. Mohammadi, M.J. Hosseinzadeh-Attar, A. Hosseinnezhad, S.H. Hosseini, M.R. Eshraghian, M.K. Nezhad, M. Rahmani, and M. Karimi Compare the effects of different visfatin concentration on cardiovascular risk factors, adiponectin and insulin resistance in patients with T2DM Diabetes & Metabolic Syndrome: Clinical Research & Reviews 5 2011 71 75
22. P. Nain, V. Saini, S. Sharma, and J. Nain Antidiabetic and antioxidant potential of Emblica officinalis Gaertn. leaves extract in streptozotocin- induced type-2 diabetes mellitus (T2DM) rats Journal of Ethnopharmacology 142 2012 65 71
23. K. Nakashima, N. Abe, F. Kamiya, T. Ito, M. Oyama, and M. Iinuma Novel flavonoids in Dragon's blood of Daemonorops draco Helvetica Chimica Acta 92 2009 1999 2008
24. E. Phielix, and M. Mensink Type 2 diabetes mellitus and skeletal muscle metabolic function Physiology & Behavior 94 2008 252 258
25. A.D. Pradhan, J.A.E. Manson, N. Rifai, J.E. Buring, and P.M. Ridker C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus Journal of the American Medical Association 286 2001 327 334
26. T. Ruge, J.A. Lockton, F. Renstrom, T. Lystig, V. Sukonina, M.K. Svensson, and J.W. Eriksson Acute hyperinsulinemia raises plasma interleukin-6 in both nondiabetic and type 2 diabetes mellitus subjects, and this effect is inversely associated with body mass index Metabolism 58 2009 860 866
27. A. Sepici-Dincel, S. Acikgoz, C. Cevik, M. Sengelen, and E. Yesilada Effects of in vivo antioxidant enzyme activities of myrtle oil in normoglycaemic and alloxan diabetic rabbits Journal of Ethnopharmacology 110 2007 498 503
28. A. Sjoholm, and T. Nystrom Endothelial inflammation in insulin resistance Lancet 365 2005 610 612
29. M. Snel, J.A. van Diepen, T. Stijnen, H. Pijl, J.A. Romijn, A.E. Meinders, P. Voshol, and I.M. Jazet Immediate and long-term effects of addition of exercise to a 16-week very low calorie diet on low-grade inflammation in obese, insulin-dependent type 2 diabetic patients Food and Chemical Toxicology 49 2011 3104 3111
30. K. Srinivasan, B. Viswanad, L. Asrat, C.L. Kaul, and P. Ramarao Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening Pharmacological Research 52 2005 313 320
31. S. Subramanian, and A. Chait Hypertriglyceridemia secondary to obesity and diabetes Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1821 2012 819 825
32. M. Suzuki, and M. Mihara Adiponectin induces CCL20 expression synergistically with IL-6 and TNF-α in THP-1 macrophages Cytokine 58 2012 344 350
33. Renjiu Tang, W.D. Wei Hong, and Bi Ningji Chemical constituents of the petroleum ether and ethyl acetate extract of Sanguis draxonis (Guangxi, China) China Journal of Chinese Materia Medica 20 1995 421 423
34. J. Teague, A. Gyte, J.E. Peel, K.C. Young, S.J.G. Loxham, R.M. Mayers, and S.M. Poucher Reversibility of hyperglycaemia and islet abnormalities in the high fat-fed female ZDF rat model of type 2 diabetes Journal of Pharmacological and Toxicological Methods 63 2011 15 23
35. Peng-fei Tu, Yu-fang Wang, Y.L. Shao Jie, and X. Wei Study on optimum extraction process of total flavonoids in Resina Draconis Chinese Journal of Experimental Traditional Medical Formulae 17 2011 30 32
36. M.I. Waly, M.M. Essa, and A. Ali The global burden of type 2 diabetes: a review International Journal of Biological & Medical Research 1 2010 326 329
37. Hong Wei, Wen Dongxu, Liu Xiaosong, and Renjiu Tang Chemical constituents of the petroleum ether and ethyl acetate extract of Sanguis draxonis (Guangxi, China) (II) China Journal of Chinese Materia Medica 23 1998 616 618
38. S-Y Yang, Y-B Lu, Q-T Zheng, and Y Lu Loureirin A. Acta Crystallographica Section E 63 2007 o3927
39. J. Zhang, L. Chen, J. Zheng, T. Zeng, H. Li, H. Xiao, X. Deng, and X. Hu The protective effect of resveratrol on islet insulin secretion and morphology in mice on a high-fat diet Diabetes Research and Clinical Practice 97 2012 474 482
40. T. Zheng, G. Shu, Z. Yang, S. Mo, Y. Zhao, and Z. Mei Antidiabetic effect of total saponins from Entada phaseoloides (L.) Merr. in type 2 diabetic rats Journal of Ethnopharmacology 139 2012 814 821