Fate plasticity of adult hippocampal progenitors: biological relevance and therapeutic use

Trends in Pharmacological Sciences

Volumn 30, Issue 2, 2009, Pages 61-65

  Jessberger, Sebastian ^a   Gage, Fred H ^b  

^a ETH ZURICH   (Switzerland)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; MESSENGER RNA; TRANSCRIPTION FACTOR MASH1;

ALLERGIC ENCEPHALOMYELITIS; ARTICLE; ASCL1 GENE; CELL DIFFERENTIATION; CELL FATE; CELL LINEAGE; EMBRYO; GENE; GENE INDUCTION; GENE OVEREXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN CELL; IN VIVO STUDY; MULTIPLE SCLEROSIS; NERVE CELL PLASTICITY; NEURAL STEM CELL; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT STEM CELLS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL LINEAGE; HIPPOCAMPUS; HUMANS; NEURONAL PLASTICITY; NEURONS; OLIGODENDROGLIA;

EID: 59349100298     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tips.2008.11.003     Document Type: Article

References (34)

1. Gage F.H. Mammalian neural stem cells. Science 287 (2000) 1433-1438
2. Zhao C., et al. Mechanisms and functional implications of adult neurogenesis. Cell 132 (2008) 645-660
3. Goldman S.A. Disease targets and strategies for the therapeutic modulation of endogenous neural stem and progenitor cells. Clin. Pharmacol. Ther. 82 (2007) 453-460
4. Kempermann G., et al. Milestones of neuronal development in the adult hippocampus. Trends Neurosci. 27 (2004) 447-452
5. van Praag H., et al. Functional neurogenesis in the adult hippocampus. Nature 415 (2002) 1030-1034
6. Parent J.M., et al. Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J. Neurosci. 17 (1997) 3727-3738
7. Kempermann G., et al. Neuroplasticity in old age: sustained fivefold induction of hippocampal neurogenesis by long-term environmental enrichment. Ann. Neurol. 52 (2002) 135-143
8. Santarelli L., et al. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301 (2003) 805-809
9. Palmer T.D., et al. FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain. Mol. Cell. Neurosci. 6 (1995) 474-486
10. Jessberger S., et al. Directed differentiation of hippocampal stem/progenitor cells in the adult brain. Nat. Neurosci. 11 (2008) 888-893
11. Walker T.L., et al. Latent stem and progenitor cells in the hippocampus are activated by neural excitation. J. Neurosci. 28 (2008) 5240-5247
12. Babu H., et al. Enriched monolayer precursor cell cultures from micro-dissected adult mouse dentate gyrus yield functional granule cell-like neurons. PLoS One 2 (2007) e388
13. Palmer T.D., et al. Cell culture. Progenitor cells from human brain after death. Nature 411 (2001) 42-43
14. Gabay L., et al. Deregulation of dorsoventral patterning by FGF confers trilineage differentiation capacity on CNS stem cells in vitro. Neuron 40 (2003) 485-499
15. Suh H., et al. In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. Cell Stem Cell 1 (2007) 515-528
16. Petryniak M.A., et al. Dlx1 and Dlx2 control neuronal versus oligodendroglial cell fate acquisition in the developing forebrain. Neuron 55 (2007) 417-433
17. Battiste J., et al. Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development 134 (2007) 285-293
18. Galichet C., et al. Neurogenin 2 has an essential role in development of the dentate gyrus. Development 135 (2008) 2031-2041
19. Yu J., et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 318 (2007) 1917-1920
20. Takahashi K., et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131 (2007) 861-872
21. Takahashi K., and Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126 (2006) 663-676
22. Jaenisch R., and Young R. Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132 (2008) 567-582
23. Zhou Q., et al. In vivo reprogramming of adult pancreatic exocrine cells to β-cells. Nature 455 (2008) 627-632
24. Meissner A., et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454 (2008) 766-770
25. Goldman S.A., and Natesan S. A niche-defying feat: induced oligoneogenesis in the adult dentate gyrus. Cell Stem Cell 3 (2008) 125-126
26. Horner P.J., et al. Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. J. Neurosci. 20 (2000) 2218-2228
27. Frielingsdorf H., et al. No evidence for new dopaminergic neurons in the adult mammalian substantia nigra. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 10177-10182
28. Song H., et al. Astroglia induce neurogenesis from adult neural stem cells. Nature 417 (2002) 39-44
29. Lie D.C., et al. The adult substantia nigra contains progenitor cells with neurogenic potential. J. Neurosci. 22 (2002) 6639-6649
30. Parras C.M., et al. Mash1 specifies neurons and oligodendrocytes in the postnatal brain. EMBO J. 23 (2004) 4495-4505
31. Keegan B.M., and Noseworthy J.H. Multiple sclerosis. Annu. Rev. Med. 53 (2002) 285-302
32. Aharoni R., et al. Neurogenesis and neuroprotection induced by peripheral immunomodulatory treatment of experimental autoimmune encephalomyelitis. J. Neurosci. 25 (2005) 8217-8228
33. Murre C., et al. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell 58 (1989) 537-544
34. Merkle F.T., et al. Mosaic organization of neural stem cells in the adult brain. Science 317 (2007) 381-384