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Volumn 30, Issue 2, 2012, Pages 337-353

Systematic evaluation of magnetic resonance imaging and spectroscopy techniques for imaging a transgenic model of alzheimer's disease (AβPP/PS1)

Author keywords

ADC maps; Alzheimer's disease; MRI; MRS; MT maps; transgenic mice; ventricle enlargement

Indexed keywords

AMYLOID PRECURSOR PROTEIN; CHOLINE; CREATINE; PRESENILIN 1;

EID: 84861521842     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-2012-111967     Document Type: Article
Times cited : (16)

References (71)
  • 1
    • 33750510024 scopus 로고    scopus 로고
    • Alzheimer 100-highlights in the history of Alzheimer research
    • Jellinger KA (2006) Alzheimer 100-highlights in the history of Alzheimer research. J Neural Transm 113, 1603-1623.
    • (2006) J Neural Transm , vol.113 , pp. 1603-1623
    • Jellinger, K.A.1
  • 2
    • 33750705653 scopus 로고    scopus 로고
    • A century of Alzheimer's disease
    • DOI 10.1126/science.1132814
    • Goedert M, Spillantini MG (2006) A century of Alzheimer's disease. Science 314, 777-781. (Pubitemid 44706636)
    • (2006) Science , vol.314 , Issue.5800 , pp. 777-781
    • Goedert, M.1    Spillantini, M.G.2
  • 4
    • 0141596079 scopus 로고    scopus 로고
    • Transgenic mouse models of Alzheimer's disease: Phenotype and application
    • Higgins GA, Jacobsen H (2003) Transgenic mouse models of Alzheimer's disease: Phenotype and application. Behav Pharmacol 14, 419-438. (Pubitemid 37176800)
    • (2003) Behavioural Pharmacology , vol.14 , Issue.5-6 , pp. 419-438
    • Higgins, G.A.1    Jacobsen, H.2
  • 5
    • 33646126924 scopus 로고    scopus 로고
    • A decade of modeling Alzheimer's disease in transgenic mice
    • McGowan E, Eriksen J, Hutton M (2006) A decade of modeling Alzheimer's disease in transgenic mice. Trends Genet 22, 281-289.
    • (2006) Trends Genet , vol.22 , pp. 281-289
    • McGowan, E.1    Eriksen, J.2    Hutton, M.3
  • 6
    • 77954319047 scopus 로고    scopus 로고
    • The usefulness and challenges of trans-genic mouse models in the study of Alzheimer's disease
    • Wilcock DM (2010) The usefulness and challenges of trans-genic mouse models in the study of Alzheimer's disease. CNS Neurol Disord Drug Targets 9, 386-394.
    • (2010) CNS Neurol Disord Drug Targets , vol.9 , pp. 386-394
    • Wilcock, D.M.1
  • 7
    • 0030832920 scopus 로고    scopus 로고
    • Temporal lobe magnetic resonance imaging can differentiate Alzheimer's disease from normal ageing, depression, vascular dementia and other causes of cognitive impairment
    • DOI 10.1017/S0033291797005606
    • O'Brein JT, Desmond P, Ames D, Schweitzer I, Chiu E, Tress B (1997) Temporal lobe magnetic resonance imaging can differentiate Alzheimer's disease from normal ageing, depression, vascular dementia and other causes of cognitive impairment. Psychol Med 27, 1267-1275. (Pubitemid 27494092)
    • (1997) Psychological Medicine , vol.27 , Issue.6 , pp. 1267-1275
    • O'Brien, J.T.1    Desmond, P.2    Ames, D.3    Schweitzer, I.4    Chiu, E.5    Tress, B.6
  • 8
    • 0037293284 scopus 로고    scopus 로고
    • Neuroimaging and early diagnosis of alzheimer disease: A look to the future
    • DOI 10.1148/radiol.2262011600
    • Petrella JR, Coleman RE, Doraiswamy PM (2003) Neu-roimaging and early diagnosis of Alzheimer disease: A look to the future. Radiology 226, 315-336. (Pubitemid 36313415)
    • (2003) Radiology , vol.226 , Issue.2 , pp. 315-336
    • Petrella, J.R.1    Coleman, R.E.2    Doraiswamy, P.M.3
  • 14
    • 33646173272 scopus 로고    scopus 로고
    • In vivo MRI and histological evaluation of brain atrophy in APP/PS1 transgenic mice
    • Delatour B, Guegan M, Volk A, Dhenain M (2006) In vivo MRI and histological evaluation of brain atrophy in APP/PS1 transgenic mice. Neurobiol Aging 27, 835-847.
    • (2006) Neurobiol Aging , vol.27 , pp. 835-847
    • Delatour, B.1    Guegan, M.2    Volk, A.3    Dhenain, M.4
  • 15
    • 36049017075 scopus 로고    scopus 로고
    • Automated segmentation of the actively stained mouse brain using multi-spectral MR microscopy
    • DOI 10.1016/j.neuroimage.2007.08.028, PII S1053811907007574
    • Sharief AA, Badea A, Dale AM, Johnson GA (2008) Automated segmentation of the actively stained mouse brain using multi-spectral MR microscopy. Neuroimage 39, 136-145. (Pubitemid 350102215)
    • (2008) NeuroImage , vol.39 , Issue.1 , pp. 136-145
    • Sharief, A.A.1    Badea, A.2    Dale, A.M.3    Johnson, G.A.4
  • 16
    • 34447095438 scopus 로고    scopus 로고
    • Animal models of neurodegenerative disease: Insights from in vivo imaging studies
    • DOI 10.1007/s11307-007-0093-4, Molecular Imaging in the Evaluation of Neurodegenerative Diseases
    • Strome EM, Doudet DJ (2007) Animal models of neurode-generative disease: Insights from in vivo imaging studies. Mol Imaging Biol 9, 186-195. (Pubitemid 47028734)
    • (2007) Molecular Imaging and Biology , vol.9 , Issue.4 , pp. 186-195
    • Strome, E.M.1    Doudet, D.J.2
  • 21
    • 0034847176 scopus 로고    scopus 로고
    • Neurodegenerative changes associated with β-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes
    • DOI 10.1006/exnr.2001.7717
    • Kurt MA, Davies DC, Kidd M, Duff K, Rolph SC, Jennings KH, Howlett DR (2001) Neurodegenerative changes associated with beta-amyloid deposition in the brains of mice carrying mutant amyloid precursor protein and mutant presenilin-1 transgenes. Exp Neurol 171, 59-71. (Pubitemid 32848445)
    • (2001) Experimental Neurology , vol.171 , Issue.1 , pp. 59-71
    • Kurt, M.A.1    Davies, D.C.2    Kidd, M.3    Duff, K.4    Rolph, S.C.5    Jennings, K.H.6    Howlett, D.R.7
  • 25
    • 23844557503 scopus 로고    scopus 로고
    • Diffusion-weighted imaging of edema following traumatic brain injury in rats: Effects of secondary hypoxia
    • DOI 10.1089/neu.2005.22.857
    • Van Putten HP, Bouwhuis MG, Muizelaar JP, Lyeth BG, Berman RF (2005) Diffusion-weighted imagingof edema following traumatic brain injury in rats: Effects of secondary hypoxia. J Neurotrauma 22, 857-872. (Pubitemid 41153871)
    • (2005) Journal of Neurotrauma , vol.22 , Issue.8 , pp. 857-872
    • Van Putten, H.P.1    Bouwhuis, M.G.2    Muizelaar, J.P.3    Lyeth, B.G.4    Berman, R.F.5
  • 27
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • DOI 10.1002/mrm.1910300604
    • Provencher SW (1993) Estimation of metabolite concentrations from localized in vivoproton NMR spectra. Magn Reson Med 30, 672-679. (Pubitemid 23360802)
    • (1993) Magnetic Resonance in Medicine , vol.30 , Issue.6 , pp. 672-679
    • Provencher, S.W.1
  • 32
    • 4644238758 scopus 로고    scopus 로고
    • The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human β-amyloid precursor protein transgenic mice
    • DOI 10.1016/j.neurobiolaging.2004.01.005, PII S0197458004000430
    • Lee JY, Friedman JE, Angel I, Kozak A, Koh JY (2004) The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice. Neurobiol Aging 25, 1315-1321. (Pubitemid 39299169)
    • (2004) Neurobiology of Aging , vol.25 , Issue.10 , pp. 1315-1321
    • Lee, J.-Y.1    Friedman, J.E.2    Angel, I.3    Kozak, A.4    Koh, J.-Y.5
  • 34
    • 78650930400 scopus 로고    scopus 로고
    • Volumetric MRI and MRS provide sensitive measures of Alzheimer's disease neuropathology in inducible Tau transgenic mice (rTg4510)
    • Yang D, Xie Z, Stephenson D, Morton D, Hicks CD, Brown TM, Sriram R, O'Neill S, Raunig D, Bocan T (2011) Volumetric MRI and MRS provide sensitive measures of Alzheimer's disease neuropathology in inducible Tau transgenic mice (rTg4510). Neuroimage 54, 2652-2658.
    • (2011) Neuroimage , vol.54 , pp. 2652-2658
    • Yang, D.1    Xie, Z.2    Stephenson, D.3    Morton, D.4    Hicks, C.D.5    Brown, T.M.6    Sriram, R.7    O'Neill, S.8    Raunig, D.9    Bocan, T.10
  • 35
    • 45849094758 scopus 로고    scopus 로고
    • Longitudinal neuroanatomical changes determined by deformation-based morphometry in a mouse model of Alzheimer's disease
    • Lau JC, Lerch JP, Sled JG, Henkelman RM, Evans AC, Bedell BJ (2008) Longitudinal neuroanatomical changes determined by deformation-based morphometry in a mouse model of Alzheimer's disease. Neuroimage 42, 19-27.
    • (2008) Neuroimage , vol.42 , pp. 19-27
    • Lau, J.C.1    Lerch, J.P.2    Sled, J.G.3    Henkelman, R.M.4    Evans, A.C.5    Bedell, B.J.6
  • 37
    • 11844258289 scopus 로고    scopus 로고
    • Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span
    • DOI 10.1016/j.nbd.2004.09.005, PII S0969996104002220
    • von Kienlin M, Kunnecke B, Metzger F, Steiner G, Richards JG, Ozmen L, Jacobsen H, Loetscher H (2005) Altered metabolic profile in the frontal cortex of PS2APP transgenic mice, monitored throughout their life span. Neurobiol Dis 18, 32-39. (Pubitemid 40092895)
    • (2005) Neurobiology of Disease , vol.18 , Issue.1 , pp. 32-39
    • Von Kienlin, M.1    Kunnecke, B.2    Metzger, F.3    Steiner, G.4    Richards, J.G.5    Ozmen, L.6    Jacobsen, H.7    Loetscher, H.8
  • 38
    • 50849121987 scopus 로고    scopus 로고
    • Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database
    • Nestor SM, Rupsingh R, Borrie M, Smith M, Accomazzi V, Wells JL, Fogarty J, Bartha R (2008) Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database. Brain 131, 2443-2454.
    • (2008) Brain , vol.131 , pp. 2443-2454
    • Nestor, S.M.1    Rupsingh, R.2    Borrie, M.3    Smith, M.4    Accomazzi, V.5    Wells, J.L.6    Fogarty, J.7    Bartha, R.8
  • 42
    • 84859375053 scopus 로고    scopus 로고
    • Characterizing the regional structural difference of the brain between tau transgenic (rTg4510) and wild-type mice using MRI
    • Xie Z, Yang D, Stephenson D, Morton D, Hicks C, Brown T, Bocan T (2010) Characterizing the regional structural difference of the brain between tau transgenic (rTg4510) and wild-type mice using MRI. Med Image Comput Comput Assist Interv 13, 308-315.
    • (2010) Med Image Comput Comput Assist Interv , vol.13 , pp. 308-315
    • Xie, Z.1    Yang, D.2    Stephenson, D.3    Morton, D.4    Hicks, C.5    Brown, T.6    Bocan, T.7
  • 43
    • 80053625550 scopus 로고    scopus 로고
    • A lifespan MRI evaluation of ventricular enlargement in normal aging mice
    • Chen CC, Tung YY, Chang C (2011) A lifespan MRI evaluation of ventricular enlargement in normal aging mice. Neurobiol Aging 32, 2299-2307.
    • (2011) Neurobiol Aging , vol.32 , pp. 2299-2307
    • Chen, C.C.1    Tung, Y.Y.2    Chang, C.3
  • 47
    • 0036338719 scopus 로고    scopus 로고
    • Magnetization transfer ratio in mild cognitive impairment and dementia of Alzheimer's type
    • DOI 10.1006/nimg.2001.0992
    • Kabani NJ, Sled JG, Chertkow H (2002) Magnetization transfer ratio in mild cognitive impairment and dementia of Alzheimer's type. Neuroimage 15, 604-610. (Pubitemid 34852528)
    • (2002) NeuroImage , vol.15 , Issue.3 , pp. 604-610
    • Kabani, N.J.1    Sled, J.G.2    Chertkow, H.3
  • 48
    • 0033846931 scopus 로고    scopus 로고
    • Magnetization transfer measurements of the hippocampus in patients with Alzheimer's disease, vascular dementia, and other types of dementia
    • Hanyu H, Asano T, Iwamoto T, Takasaki M, Shindo H, Abe K (2000) Magnetization transfer measurements of the hippocampus in patients with Alzheimer's disease, vascular dementia, and other types of dementia. AJNR Am J Neurora-diol 21, 1235-1242. (Pubitemid 30655657)
    • (2000) American Journal of Neuroradiology , vol.21 , Issue.7 , pp. 1235-1242
    • Hanyu, H.1    Asano, T.2    Iwamoto, T.3    Takasaki, M.4    Shindo, H.5    Abe, K.6
  • 49
    • 0035878588 scopus 로고    scopus 로고
    • Magnetization transfer measurements of the hippocampus in the early diagnosis of Alzheimer's disease
    • DOI 10.1016/S0022-510X(01)00553-6, PII S0022510X01005536
    • Hanyu H, Asano T, Sakurai H, Takasaki M, Shindo H, Abe K (2001) Magnetization transfer measurements of the hippocampus in the early diagnosis of Alzheimer's disease. J Neurol Sci 188, 79-84. (Pubitemid 32727877)
    • (2001) Journal of the Neurological Sciences , vol.188 , Issue.1-2 , pp. 79-84
    • Hanyu, H.1    Asano, T.2    Sakurai, H.3    Takasaki, M.4    Shindo, H.5    Abe, K.6
  • 53
    • 0035340273 scopus 로고    scopus 로고
    • Acute and chronic changes of the apparent diffusion coefficient in neurological disorders-biophysical mechanisms and possible underlying histopathology
    • Gass A, Niendorf T, Hirsch JG (2001) Acute and chronic changes of the apparent diffusion coefficient in neurological disorders-biophysical mechanisms and possible underlying histopathology. J Neurol Sci 186 (Suppl 1), S15-S23.
    • (2001) J Neurol Sci , vol.186 , Issue.SUPPL. 1
    • Gass, A.1    Niendorf, T.2    Hirsch, J.G.3
  • 55
    • 0027322890 scopus 로고
    • Alzheimer disease: Depiction of increased cerebral myo-inositol with proton MR spectroscopy
    • Miller BL, Moats RA, Shonk T, Ernst T, Woolley S, Ross BD (1993) Alzheimer disease: Depiction of increased cerebral myo-inositol with proton MR spectroscopy. Radiology 187, 433-437. (Pubitemid 23127850)
    • (1993) Radiology , vol.187 , Issue.2 , pp. 433-437
    • Miller, B.L.1    Moats, R.A.2    Shonk, T.3    Ernst, T.4    Woolley, S.5    Ross, B.D.6
  • 56
    • 0028244281 scopus 로고
    • Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease
    • DOI 10.1002/mrm.1910320115
    • Moats RA, Ernst T, Shonk TK, Ross BD (1994) Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease. Magn Reson Med 32, 110-115. (Pubitemid 24198562)
    • (1994) Magnetic Resonance in Medicine , vol.32 , Issue.1 , pp. 110-115
    • Moats, R.A.1    Ernst, T.2    Shonk, T.K.3    Ross, B.D.4
  • 61
    • 0035852992 scopus 로고    scopus 로고
    • Magnetic resonance spec-troscopy in AD
    • Valenzuela MJ, Sachdev P (2001) Magnetic resonance spec-troscopy in AD. Neurology 56, 592-598.
    • (2001) Neurology , vol.56 , pp. 592-598
    • Valenzuela, M.J.1    Sachdev, P.2
  • 62
    • 64149098278 scopus 로고    scopus 로고
    • Regional metabolic changesinthe hippocampus and posterior cingulate area detected with 3-Tesla magnetic resonance spectroscopy in patients with mild cognitive impairment and Alzheimer disease
    • Wang Z, Zhao C, Yu L, Zhou W, Li K (2009) Regional metabolic changesinthe hippocampus and posterior cingulate area detected with 3-Tesla magnetic resonance spectroscopy in patients with mild cognitive impairment and Alzheimer disease. Acta Radiol 50, 312-319.
    • (2009) Acta Radiol , vol.50 , pp. 312-319
    • Wang, Z.1    Zhao, C.2    Yu, L.3    Zhou, W.4    Li, K.5
  • 63
    • 33645011159 scopus 로고    scopus 로고
    • MR spectroscopy of brain white matter in the prediction of dementia
    • DOI 10.1212/01.wnl.0000198256.54809.0e, PII 0000611420060228000020
    • den Heijer T, Sijens PE, Prins ND, Hofman A, Koudstaal PJ, Oudkerk M, Breteler MM (2006) MR spectroscopy of brain white matter in the prediction of dementia. Neurology 66, 540-544. (Pubitemid 43739884)
    • (2006) Neurology , vol.66 , Issue.4 , pp. 540-544
    • Den Heijer, T.1    Sijens, P.E.2    Prins, N.D.3    Hofman, A.4    Koudstaal, P.J.5    Oudkerk, M.6    Breteler, M.M.B.7
  • 67
    • 79955643508 scopus 로고    scopus 로고
    • Leptin induces proliferation of neuronal progenitors and neuroprotectioninamouse modelofAlzheimer's disease
    • Perez-Gonzalez R, Antequera D, Vargas T, Spuch C, Bolos M, Carro E (2011) Leptin induces proliferation of neuronal progenitors and neuroprotectioninamouse modelofAlzheimer's disease. J Alzheimers Dis 24 (Suppl 2), 17-25.
    • (2011) J Alzheimers Dis , vol.24 , Issue.SUPPL. 2 , pp. 17-25
    • Perez-Gonzalez, R.1    Antequera, D.2    Vargas, T.3    Spuch, C.4    Bolos, M.5    Carro, E.6
  • 69
    • 0021956721 scopus 로고
    • 'Autocannibalism' of choline-containing membrane phospholipids in the pathogenesis of Alzheimer's disease - A hypothesis
    • DOI 10.1016/0197-0186(85)90127-5
    • Wurtman RJ, Blusztajn JK, Maire JC (1985) "Autocanni-balism" of choline-containing membrane phospholipids in the pathogenesis of Alzheimer's disease-A hypothesis. Neurochem Int 7, 369-372. (Pubitemid 15116219)
    • (1985) Neurochemistry International , vol.7 , Issue.2 , pp. 369-372
    • Wurtman, R.J.1    Blustajn, J.K.2    Maire, J.-C.3
  • 70
    • 65449150553 scopus 로고    scopus 로고
    • In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment
    • Westman E, Spenger C, Oberg J, Reyer H, Pahnke J, Wahlund LO (2009) In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatment. BMC Neurosci 10, 33.
    • (2009) BMC Neurosci , vol.10-33
    • Westman, E.1    Spenger, C.2    Oberg, J.3    Reyer, H.4    Pahnke, J.5    Wahlund, L.O.6


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