메뉴 건너뛰기




Volumn , Issue MAY, 2013, Pages

Glucose and lactate metabolism in the awake and stimulated rat: A 13C-NMR study

Author keywords

Astrocytes; Brain metabolism; Lactate; Neurons

Indexed keywords

GLUCOSE; LACTIC ACID;

EID: 84884294455     PISSN: None     EISSN: 16626427     Source Type: Journal    
DOI: 10.3389/fnene.2013.00005     Document Type: Article
Times cited : (33)

References (55)
  • 1
    • 0036200749 scopus 로고    scopus 로고
    • Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: effects of hyperglycemia and hypoglycemia
    • doi: 10.1097/00004647-200203000-00004
    • Abi-Saab, W. M., Maggs, D. G., Jones, T., Jacob, R., Srihari, V., Thompson, J., et al. (2002). Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: effects of hyperglycemia and hypoglycemia. J. Cereb. Blood Flow Metab. 22, 271-279. doi: 10.1097/00004647-200203000-00004
    • (2002) J. Cereb. Blood Flow Metab , vol.22 , pp. 271-279
    • Abi-Saab, W.M.1    Maggs, D.G.2    Jones, T.3    Jacob, R.4    Srihari, V.5    Thompson, J.6
  • 2
    • 33748272252 scopus 로고    scopus 로고
    • Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons
    • doi: 10.1038/sj.jcbfm.9600281
    • Bak, L. K., Schousboe, A., Sonnewald, U., and Waagepetersen, H. S. (2006). Glucose is necessary to maintain neurotransmitter homeostasis during synaptic activity in cultured glutamatergic neurons. J. Cereb. Blood Flow Metab. 26, 1285-1297. doi: 10.1038/sj.jcbfm.9600281
    • (2006) J. Cereb. Blood Flow Metab , vol.26 , pp. 1285-1297
    • Bak, L.K.1    Schousboe, A.2    Sonnewald, U.3    Waagepetersen, H.S.4
  • 3
    • 0031595179 scopus 로고    scopus 로고
    • 13C] aspartate metabolism in cultured cortical astrocytes and cerebellar granule neurons studied by NMR spectroscopy
    • doi: 10.1002/(SICI)1098-1136(199807)23:3<271::AID-GLIA9>3.0.CO;2-7
    • 13C] aspartate metabolism in cultured cortical astrocytes and cerebellar granule neurons studied by NMR spectroscopy. Glia 23, 271-277. doi: 10.1002/(SICI)1098-1136(199807)23:3<271::AID-GLIA9>3.0.CO;2-7
    • (1998) Glia , vol.23 , pp. 271-277
    • Bakken, I.J.1    White, L.R.2    Aasly, J.3    Unsgard, G.4    Sonnewald, U.5
  • 4
    • 84861851015 scopus 로고    scopus 로고
    • Is lactate a volume transmitter of metabolic states of the brain?
    • doi: 10.3389/fnene.2012.00005
    • Bergersen, L. H., and Gjedde, A. (2012). Is lactate a volume transmitter of metabolic states of the brain? Front. Neuroenergetics 4:5. doi: 10.3389/fnene.2012.00005
    • (2012) Front. Neuroenergetics , vol.4-5
    • Bergersen, L.H.1    Gjedde, A.2
  • 5
    • 25144447755 scopus 로고    scopus 로고
    • The astrocyte-neuron lactate shuttle: a debated but still valuable hypothesis for brain imaging
    • doi: 10.1038/sj.jcbfm.9600127
    • Bonvento, G., Herard, A. S., and Voutsinos-Porche, B. (2005). The astrocyte-neuron lactate shuttle: a debated but still valuable hypothesis for brain imaging. J. Cereb. Blood Flow Metab. 25, 1394-1399. doi: 10.1038/sj.jcbfm.9600127
    • (2005) J. Cereb. Blood Flow Metab , vol.25 , pp. 1394-1399
    • Bonvento, G.1    Herard, A.S.2    Voutsinos-Porche, B.3
  • 7
    • 0032587077 scopus 로고    scopus 로고
    • [1-(13)C]glucose metabolism in the tumoral and nontumoral cerebral tissue of a glioma-bearing rat
    • doi: 10.1046/j.1471-4159.1999.0722445.x
    • Bouzier, A. K., Quesson, B., Valeins, H., Canioni, P., and Merle, M. (1999). [1-(13)C]glucose metabolism in the tumoral and nontumoral cerebral tissue of a glioma-bearing rat. J. Neurochem. 72, 2445-2455. doi: 10.1046/j.1471-4159.1999.0722445.x
    • (1999) J. Neurochem , vol.72 , pp. 2445-2455
    • Bouzier, A.K.1    Quesson, B.2    Valeins, H.3    Canioni, P.4    Merle, M.5
  • 8
    • 0033623793 scopus 로고    scopus 로고
    • The metabolism of [3-(13)C]lactate in the rat brain is specific of a pyruvate carboxylase-deprived compartment
    • doi: 10.1046/j.1471-4159.2000.0750480.x
    • Bouzier, A. K., Thiaudiere, E., Biran, M., Rouland, R., Canioni, P., and Merle, M. (2000). The metabolism of [3-(13)C]lactate in the rat brain is specific of a pyruvate carboxylase-deprived compartment. J. Neurochem. 75, 480-486. doi: 10.1046/j.1471-4159.2000.0750480.x
    • (2000) J. Neurochem , vol.75 , pp. 480-486
    • Bouzier, A.K.1    Thiaudiere, E.2    Biran, M.3    Rouland, R.4    Canioni, P.5    Merle, M.6
  • 9
    • 0036556478 scopus 로고    scopus 로고
    • Feeding active neurons: (re)emergence of a nursing role for astrocytes
    • doi: 10.1016/S0928-4257(02)00016-5
    • Bouzier-Sore, A. K., Merle, M., Magistretti, P. J., and Pellerin, L. (2002). Feeding active neurons: (re)emergence of a nursing role for astrocytes. J. Physiol. Paris 96, 273-282. doi: 10.1016/S0928-4257(02)00016-5
    • (2002) J. Physiol. Paris , vol.96 , pp. 273-282
    • Bouzier-Sore, A.K.1    Merle, M.2    Magistretti, P.J.3    Pellerin, L.4
  • 10
    • 33748896023 scopus 로고    scopus 로고
    • Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study
    • doi: 10.1111/j.1460-9568.2006.05056.x
    • Bouzier-Sore, A. K., Voisin, P., Bouchaud, V., Bezancon, E., Franconi, J. M., and Pellerin, L. (2006). Competition between glucose and lactate as oxidative energy substrates in both neurons and astrocytes: a comparative NMR study. Eur. J. Neurosci. 24, 1687-1694. doi: 10.1111/j.1460-9568.2006.05056.x
    • (2006) Eur. J. Neurosci , vol.24 , pp. 1687-1694
    • Bouzier-Sore, A.K.1    Voisin, P.2    Bouchaud, V.3    Bezancon, E.4    Franconi, J.M.5    Pellerin, L.6
  • 11
    • 0242406757 scopus 로고    scopus 로고
    • Lactate is a preferential oxidative energy substrate over glucose for neurons in culture
    • doi: 10.1097/01.WCB.0000091761.61714.25
    • Bouzier-Sore, A. K., Voisin, P., Canioni, P., Magistretti, P. J., and Pellerin, L. (2003). Lactate is a preferential oxidative energy substrate over glucose for neurons in culture. J. Cereb. Blood Flow Metab. 23, 1298-1306. doi: 10.1097/01.WCB.0000091761.61714.25
    • (2003) J. Cereb. Blood Flow Metab , vol.23 , pp. 1298-1306
    • Bouzier-Sore, A.K.1    Voisin, P.2    Canioni, P.3    Magistretti, P.J.4    Pellerin, L.5
  • 12
    • 0026615180 scopus 로고
    • 13C NMR study on fluxes into the TCA cycle of neuronal and glial tumor cell lines and primary cells
    • doi: 10.1016/0300-9084(92)90078-S
    • 13C NMR study on fluxes into the TCA cycle of neuronal and glial tumor cell lines and primary cells. Biochimie 74, 941-948. doi: 10.1016/0300-9084(92)90078-S
    • (1992) Biochimie , vol.74 , pp. 941-948
    • Brand, A.1    Engelmann, J.2    Leibfritz, D.3
  • 13
    • 71249103087 scopus 로고    scopus 로고
    • Cell-cell and intracellular lactate shuttles
    • doi: 10.1113/jphysiol.2009.178350
    • Brooks, G. A. (2009). Cell-cell and intracellular lactate shuttles. J. Physiol. 587, 5591-5600. doi: 10.1113/jphysiol.2009.178350
    • (2009) J. Physiol , vol.587 , pp. 5591-5600
    • Brooks, G.A.1
  • 14
    • 40049101679 scopus 로고    scopus 로고
    • Glutamate receptor-dependent increments in lactate, glucose and oxygen metabolism evoked in rat cerebellum in vivo
    • doi: 10.1113/jphysiol.2007.144154
    • Caesar, K., Hashemi, P., Douhou, A., Bonvento, G., Boutelle, M. G., Walls, A. B., et al. (2008). Glutamate receptor-dependent increments in lactate, glucose and oxygen metabolism evoked in rat cerebellum in vivo. J. Physiol. 586, 1337-1349. doi: 10.1113/jphysiol.2007.144154
    • (2008) J. Physiol , vol.586 , pp. 1337-1349
    • Caesar, K.1    Hashemi, P.2    Douhou, A.3    Bonvento, G.4    Boutelle, M.G.5    Walls, A.B.6
  • 15
    • 1242271187 scopus 로고    scopus 로고
    • Absence of rapid sensory adaptation in neocortex during information processing states
    • doi: 10.1016/S0896-6273(03)00853-5
    • Castro-Alamancos, M. A. (2004). Absence of rapid sensory adaptation in neocortex during information processing states. Neuron 41, 455-464. doi: 10.1016/S0896-6273(03)00853-5
    • (2004) Neuron , vol.41 , pp. 455-464
    • Castro-Alamancos, M.A.1
  • 16
    • 70349267566 scopus 로고    scopus 로고
    • Differential response patterns in the si barrel and septal compartments during mechanical whisker stimulation
    • doi: 10.1152/jn.91120.2008
    • Chakrabarti, S., and Alloway, K. D. (2009). Differential response patterns in the si barrel and septal compartments during mechanical whisker stimulation. J. Neurophysiol. 102, 1632-1646. doi: 10.1152/jn.91120.2008
    • (2009) J. Neurophysiol , vol.102 , pp. 1632-1646
    • Chakrabarti, S.1    Alloway, K.D.2
  • 17
    • 0035478762 scopus 로고    scopus 로고
    • Do active cerebral neurons really use lactate rather than glucose?
    • doi: 10.1016/S0166-2236(00)01920-2
    • Chih, C. P., Lipton, P., and Roberts, E. L. Jr. (2001). Do active cerebral neurons really use lactate rather than glucose? Trends Neurosci. 24, 573-578. doi: 10.1016/S0166-2236(00)01920-2
    • (2001) Trends Neurosci. , vol.24 , pp. 573-578
    • Chih, C.P.1    Lipton, P.2    Roberts Jr., E.L.3
  • 18
    • 0242574396 scopus 로고    scopus 로고
    • Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis
    • doi: 10.1097/01.WCB.0000081369.51727.6F
    • Chih, C. P., and Roberts, E. L. Jr. (2003). Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis. J. Cereb. Blood Flow Metab. 23, 1263-1281. doi: 10.1097/01.WCB.0000081369.51727.6F
    • (2003) J. Cereb. Blood Flow Metab , vol.23 , pp. 1263-1281
    • Chih, C.P.1    Roberts Jr., E.L.2
  • 19
    • 84866482758 scopus 로고    scopus 로고
    • Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase
    • doi: 10.1016/j.neuron.2012.08.032
    • Choi, H. B., Gordon, G. R., Zhou, N., Tai, C., Rungta, R. L., Martinez, J., et al. (2012). Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase. Neuron 75, 1094-1104. doi: 10.1016/j.neuron.2012.08.032
    • (2012) Neuron , vol.75 , pp. 1094-1104
    • Choi, H.B.1    Gordon, G.R.2    Zhou, N.3    Tai, C.4    Rungta, R.L.5    Martinez, J.6
  • 20
    • 0030833903 scopus 로고    scopus 로고
    • Local uncoupling of the cerebrovascular and metabolic responses to somatosensory stimulation after neuronal nitric oxide synthase inhibition
    • doi: 10.1097/00004647-199711000-00008
    • Cholet, N., Seylaz, J., Lacombe, P., and Bonvento, G. (1997). Local uncoupling of the cerebrovascular and metabolic responses to somatosensory stimulation after neuronal nitric oxide synthase inhibition. J. Cereb. Blood Flow Metab. 17, 1191-1201. doi: 10.1097/00004647-199711000-00008
    • (1997) J. Cereb. Blood Flow Metab , vol.17 , pp. 1191-1201
    • Cholet, N.1    Seylaz, J.2    Lacombe, P.3    Bonvento, G.4
  • 21
    • 78149491490 scopus 로고    scopus 로고
    • Predominant enhancement of glucose uptake in astrocytes versus neurons during activation of the somatosensory cortex
    • doi: 10.1523/JNEUROSCI.0762-10.2010
    • Chuquet, J., Quilichini, P., Nimchinsky, E. A., and Buzsaki, G. (2010). Predominant enhancement of glucose uptake in astrocytes versus neurons during activation of the somatosensory cortex. J. Neurosci. 30, 15298-15303. doi: 10.1523/JNEUROSCI.0762-10.2010
    • (2010) J. Neurosci , vol.30 , pp. 15298-15303
    • Chuquet, J.1    Quilichini, P.2    Nimchinsky, E.A.3    Buzsaki, G.4
  • 22
    • 0035577325 scopus 로고    scopus 로고
    • Intracellular compartmentation of pyruvate in primary cultures of cortical neurons as detected by (13)C NMR spectroscopy with multiple (13)C labels
    • doi: 10.1002/jnr.10048
    • Cruz, F., Villalba, M., Garcia-Espinosa, M. A., Ballesteros, P., Bogonez, E., Satrustegui, J., et al. (2001). Intracellular compartmentation of pyruvate in primary cultures of cortical neurons as detected by (13)C NMR spectroscopy with multiple (13)C labels. J. Neurosci. Res. 66, 771-781. doi: 10.1002/jnr.10048
    • (2001) J. Neurosci. Res , vol.66 , pp. 771-781
    • Cruz, F.1    Villalba, M.2    Garcia-Espinosa, M.A.3    Ballesteros, P.4    Bogonez, E.5    Satrustegui, J.6
  • 23
    • 84866697175 scopus 로고    scopus 로고
    • Fueling and imaging brain activation
    • doi: 10.1042/AN20120021
    • Dienel, G. A. (2012). Fueling and imaging brain activation. ASN Neuro. 4, 267-321. doi: 10.1042/AN20120021
    • (2012) ASN Neuro , vol.4 , pp. 267-321
    • Dienel, G.A.1
  • 24
    • 0035577699 scopus 로고    scopus 로고
    • Glucose and lactate metabolism during brain activation
    • doi: 10.1002/jnr.10079
    • Dienel, G. A., and Hertz, L. (2001). Glucose and lactate metabolism during brain activation. J. Neurosci. Res. 66, 824-838. doi: 10.1002/jnr.10079
    • (2001) J. Neurosci. Res , vol.66 , pp. 824-838
    • Dienel, G.A.1    Hertz, L.2
  • 25
    • 0026564899 scopus 로고
    • Extracellular brain glucose levels reflect local neuronal activity: a microdialysis study in awake, freely moving rats
    • Fellows, L. K., Boutelle, M. G., and Fillenz, M. (1992). Extracellular brain glucose levels reflect local neuronal activity: a microdialysis study in awake, freely moving rats. J. Neurochem. 59, 2141-2147.
    • (1992) J. Neurochem. , vol.59 , pp. 2141-2147
    • Fellows, L.K.1    Boutelle, M.G.2    Fillenz, M.3
  • 26
    • 0011678654 scopus 로고
    • Weak satellite signals in high-resolution NMR spectra: separating the wheat from the chaff
    • Freeman, R., Mareci, T. H., and Morris, G. A. (1981). Weak satellite signals in high-resolution NMR spectra: separating the wheat from the chaff. J. Magn. Reson. 42, 341-345.
    • (1981) J. Magn. Reson. , vol.42 , pp. 341-345
    • Freeman, R.1    Mareci, T.H.2    Morris, G.A.3
  • 27
    • 68949089810 scopus 로고    scopus 로고
    • The barrel cortex as a model to study dynamic neuroglial interaction
    • doi: 10.1177/1073858409336092
    • Giaume, C., Maravall, M., Welker, E., and Bonvento, G. (2009). The barrel cortex as a model to study dynamic neuroglial interaction. Neuroscientist 15, 351-366. doi: 10.1177/1073858409336092
    • (2009) Neuroscientist , vol.15 , pp. 351-366
    • Giaume, C.1    Maravall, M.2    Welker, E.3    Bonvento, G.4
  • 28
    • 57649118670 scopus 로고    scopus 로고
    • Brain metabolism dictates the polarity of astrocyte control over arterioles
    • doi: 10.1038/nature07525
    • Gordon, G. R., Choi, H. B., Rungta, R. L., Ellis-Davies, G. C., and MacVicar, B. A. (2008). Brain metabolism dictates the polarity of astrocyte control over arterioles. Nature 456, 745-749. doi: 10.1038/nature07525
    • (2008) Nature , vol.456 , pp. 745-749
    • Gordon, G.R.1    Choi, H.B.2    Rungta, R.L.3    Ellis-Davies, G.C.4    MacVicar, B.A.5
  • 29
    • 0033969656 scopus 로고    scopus 로고
    • Cerebral metabolism of lactate in vivo: evidence for neuronal pyruvate carboxylation
    • doi: 10.1097/00004647-200002000-00014
    • Hassel, B., and Brathe, A. (2000). Cerebral metabolism of lactate in vivo: evidence for neuronal pyruvate carboxylation. J. Cereb. Blood Flow Metab. 20, 327-336. doi: 10.1097/00004647-200002000-00014
    • (2000) J. Cereb. Blood Flow Metab , vol.20 , pp. 327-336
    • Hassel, B.1    Brathe, A.2
  • 30
    • 8344272718 scopus 로고    scopus 로고
    • The astrocyte-neuron lactate shuttle: a challenge of a challenge
    • doi: 10.1097/00004647-200411000-00008
    • Hertz, L. (2004). The astrocyte-neuron lactate shuttle: a challenge of a challenge. J. Cereb. Blood Flow Metab. 24, 1241-1248. doi: 10.1097/00004647-200411000-00008
    • (2004) J. Cereb. Blood Flow Metab , vol.24 , pp. 1241-1248
    • Hertz, L.1
  • 31
    • 0027741301 scopus 로고
    • Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy
    • Jenkins, B. G., Koroshetz, W. J., Beal, M. F., and Rosen, B. R. (1993). Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy. Neurology 43, 2689-2695.
    • (1993) Neurology , vol.43 , pp. 2689-2695
    • Jenkins, B.G.1    Koroshetz, W.J.2    Beal, M.F.3    Rosen, B.R.4
  • 32
    • 3042521444 scopus 로고    scopus 로고
    • Layer-specific somatosensory cortical activation during active tactile discrimination
    • doi: 10.1126/science.1093318
    • Krupa, D. J., Wiest, M. C., Shuler, M. G., Laubach, M., and Nicolelis, M. A. (2004). Layer-specific somatosensory cortical activation during active tactile discrimination. Science 304, 1989-1992. doi: 10.1126/science.1093318
    • (2004) Science , vol.304 , pp. 1989-1992
    • Krupa, D.J.1    Wiest, M.C.2    Shuler, M.G.3    Laubach, M.4    Nicolelis, M.A.5
  • 33
    • 0027787059 scopus 로고
    • 13C]D-glucose metabolism in cultured astrocytes and neurons using nuclear magnetic resonance spectroscopy
    • 13C]D-glucose metabolism in cultured astrocytes and neurons using nuclear magnetic resonance spectroscopy. Dev. Neurosci. 15, 282-288.
    • (1993) Dev. Neurosci. , vol.15 , pp. 282-288
    • Leo, G.C.1    Driscoll, B.F.2    Shank, R.P.3    Kaufman, E.4
  • 35
    • 0033614973 scopus 로고    scopus 로고
    • Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging
    • doi: 10.1098/rstb.1999.0471
    • Magistretti, P. J., and Pellerin, L. (1999). Cellular mechanisms of brain energy metabolism and their relevance to functional brain imaging. Philos. Trans. R. Soc. Lond. B Biol. Sci. 354, 1155-1163. doi: 10.1098/rstb.1999.0471
    • (1999) Philos. Trans. R. Soc. Lond. B Biol. Sci , vol.354 , pp. 1155-1163
    • Magistretti, P.J.1    Pellerin, L.2
  • 36
    • 34247471119 scopus 로고    scopus 로고
    • Sustained neuronal activation raises oxidative metabolism to a new steady-state level: evidence from 1H NMR spectroscopy in the human visual cortex
    • doi: 10.1038/sj.jcbfm.9600401
    • Mangia, S., Tkac, I., Gruetter, R., Van de Moortele, P. F., Maraviglia, B., and Ugurbil, K. (2007). Sustained neuronal activation raises oxidative metabolism to a new steady-state level: evidence from 1H NMR spectroscopy in the human visual cortex. J. Cereb. Blood Flow Metab. 27, 1055-1063. doi: 10.1038/sj.jcbfm.9600401
    • (2007) J. Cereb. Blood Flow Metab , vol.27 , pp. 1055-1063
    • Mangia, S.1    Tkac, I.2    Gruetter, R.3    Van de Moortele, P.F.4    Maraviglia, B.5    Ugurbil, K.6
  • 37
    • 0030006356 scopus 로고    scopus 로고
    • Mathematical modelling of the citric acid cycle for the analysis of glutamine isotopomers from cerebellar astrocytes incubated with [1(- 13)C]glucose
    • doi: 10.1111/j.1432-1033.1996.0742u.x
    • Merle, M., Martin, M., Villegier, A., and Canioni, P. (1996). Mathematical modelling of the citric acid cycle for the analysis of glutamine isotopomers from cerebellar astrocytes incubated with [1(- 13)C]glucose. Eur. J. Biochem. 239, 742-751. doi: 10.1111/j.1432-1033.1996.0742u.x
    • (1996) Eur. J. Biochem , vol.239 , pp. 742-751
    • Merle, M.1    Martin, M.2    Villegier, A.3    Canioni, P.4
  • 38
    • 0346456853 scopus 로고    scopus 로고
    • Increased lactate/pyruvate ratio augments blood flow in physiologically activated human brain
    • doi: 10.1073/pnas.0307457100
    • Mintun, M. A., Vlassenko, A. G., Rundle, M. M., and Raichle, M. E. (2004). Increased lactate/pyruvate ratio augments blood flow in physiologically activated human brain. Proc. Natl. Acad. Sci. U.S.A. 101, 659-664. doi: 10.1073/pnas.0307457100
    • (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 659-664
    • Mintun, M.A.1    Vlassenko, A.G.2    Rundle, M.M.3    Raichle, M.E.4
  • 39
    • 0018382256 scopus 로고
    • Fine structural localization of glutamine synthetase in astrocytes of rat brain
    • doi: 10.1016/0006-8993(79)90071-4
    • Norenberg, M. D., and Martinez-Hernandez, A. (1979). Fine structural localization of glutamine synthetase in astrocytes of rat brain. Brain Res. 161, 303-310. doi: 10.1016/0006-8993(79)90071-4
    • (1979) Brain Res , vol.161 , pp. 303-310
    • Norenberg, M.D.1    Martinez-Hernandez, A.2
  • 40
    • 34547823399 scopus 로고    scopus 로고
    • Activity-dependent regulation of energy metabolism by astrocytes: an update
    • doi: 10.1002/glia.20528
    • Pellerin, L., Bouzier-Sore, A. K., Aubert, A., Serres, S., Merle, M., Costalat, R., et al. (2007). Activity-dependent regulation of energy metabolism by astrocytes: an update. Glia 55, 1251-1262. doi: 10.1002/glia.20528
    • (2007) Glia , vol.55 , pp. 1251-1262
    • Pellerin, L.1    Bouzier-Sore, A.K.2    Aubert, A.3    Serres, S.4    Merle, M.5    Costalat, R.6
  • 41
    • 0028080101 scopus 로고
    • Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization
    • Pellerin, L., and Magistretti, P. J. (1994). Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proc. Natl. Acad. Sci. U.S.A. 91, 10625-10629.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 10625-10629
    • Pellerin, L.1    Magistretti, P.J.2
  • 42
    • 84863473201 scopus 로고    scopus 로고
    • Sweet sixteen for ANLS
    • doi: 10.1038/jcbfm.2011.149
    • Pellerin, L., and Magistretti, P. J. (2012). Sweet sixteen for ANLS. J. Cereb. Blood Flow Metab. 32, 1152-1166. doi: 10.1038/jcbfm.2011.149
    • (2012) J. Cereb. Blood Flow Metab , vol.32 , pp. 1152-1166
    • Pellerin, L.1    Magistretti, P.J.2
  • 43
    • 0031731776 scopus 로고    scopus 로고
    • Evidence supporting the existence of an activity-dependent astrocyte- neuron lactate shuttle
    • Pellerin, L., Pellegri, G., Bittar, P. G., Charnay, Y., Bouras, C., Martin, J. L., et al. (1998). Evidence supporting the existence of an activity-dependent astrocyte- neuron lactate shuttle. Dev. Neurosci. 20, 291-299.
    • (1998) Dev. Neurosci. , vol.20 , pp. 291-299
    • Pellerin, L.1    Pellegri, G.2    Bittar, P.G.3    Charnay, Y.4    Bouras, C.5    Martin, J.L.6
  • 44
    • 0026009448 scopus 로고
    • Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation
    • doi: 10.1073/pnas.88.13.5829
    • Prichard, J., Rothman, D., Novotny, E., Petroff, O., Kuwabara, T., Avison, M., et al. (1991). Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation. Proc. Natl. Acad. Sci. U.S.A. 88, 5829-5831. doi: 10.1073/pnas.88.13.5829
    • (1991) Proc. Natl. Acad. Sci. U.S.A , vol.88 , pp. 5829-5831
    • Prichard, J.1    Rothman, D.2    Novotny, E.3    Petroff, O.4    Kuwabara, T.5    Avison, M.6
  • 45
    • 0033625878 scopus 로고    scopus 로고
    • (13)C MR spectroscopy study of lactate as substrate for rat brain
    • doi: 10.1159/000017472
    • Qu, H., Haberg, A., Haraldseth, O., Unsgard, G., and Sonnewald, U. (2000). (13)C MR spectroscopy study of lactate as substrate for rat brain. Dev. Neurosci. 22, 429-436. doi: 10.1159/000017472
    • (2000) Dev. Neurosci , vol.22 , pp. 429-436
    • Qu, H.1    Haberg, A.2    Haraldseth, O.3    Unsgard, G.4    Sonnewald, U.5
  • 47
    • 0026643890 scopus 로고
    • Effect of photic stimulation on human visual cortex lactate and phosphates using 1H and 31P magnetic resonance spectroscopy
    • doi: 10.1038/jcbfm.1992.82
    • Sappey-Marinier, D., Calabrese, G., Fein, G., Hugg, J. W., Biggins, C., and Weiner, M. W. (1992). Effect of photic stimulation on human visual cortex lactate and phosphates using 1H and 31P magnetic resonance spectroscopy. J. Cereb. Blood Flow Metab. 12, 584-592. doi: 10.1038/jcbfm.1992.82
    • (1992) J. Cereb. Blood Flow Metab , vol.12 , pp. 584-592
    • Sappey-Marinier, D.1    Calabrese, G.2    Fein, G.3    Hugg, J.W.4    Biggins, C.5    Weiner, M.W.6
  • 48
    • 0031239613 scopus 로고    scopus 로고
    • Trafficking between glia and neurons of TCA cycle intermediates and related metabolites
    • doi: 10.1002/(SICI)1098-1136(199709)21:1<99::AID-GLIA11>3.0.CO;2-W
    • Schousboe, A., Westergaard, N., Waagepetersen, H. S., Larsson, O. M., Bakken, I. J., and Sonnewald, U. (1997). Trafficking between glia and neurons of TCA cycle intermediates and related metabolites. Glia 21, 99-105. doi: 10.1002/(SICI)1098-1136(199709)21:1<99::AID-GLIA11>3.0.CO;2-W
    • (1997) Glia , vol.21 , pp. 99-105
    • Schousboe, A.1    Westergaard, N.2    Waagepetersen, H.S.3    Larsson, O.M.4    Bakken, I.J.5    Sonnewald, U.6
  • 49
    • 0031731914 scopus 로고    scopus 로고
    • Brain anaerobic lactate production: a suicide note or a survival kit? Dev
    • Schurr, A., and Rigor, B. M. (1998). Brain anaerobic lactate production: a suicide note or a survival kit? Dev. Neurosci. 20, 348-357.
    • (1998) Neurosci. , vol.20 , pp. 348-357
    • Schurr, A.1    Rigor, B.M.2
  • 50
    • 0019347815 scopus 로고
    • The deoxyglucose method for the measurement of local glucose utilization and the mapping of local functional activity in the central nervous system
    • Sokoloff, L. (1981). The deoxyglucose method for the measurement of local glucose utilization and the mapping of local functional activity in the central nervous system. Int. Rev. Neurobiol. 22, 287-333.
    • (1981) Int. Rev. Neurobiol. , vol.22 , pp. 287-333
    • Sokoloff, L.1
  • 51
    • 0037461719 scopus 로고    scopus 로고
    • Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex
    • doi: 10.1016/S0896-6273(02)01170-4
    • Voutsinos-Porche, B., Bonvento, G., Tanaka, K., Steiner, P., Welker, E., Chatton, J. Y., et al. (2003). Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex. Neuron 37, 275-286. doi: 10.1016/S0896-6273(02)01170-4
    • (2003) Neuron , vol.37 , pp. 275-286
    • Voutsinos-Porche, B.1    Bonvento, G.2    Tanaka, K.3    Steiner, P.4    Welker, E.5    Chatton, J.Y.6
  • 54
    • 79956330533 scopus 로고    scopus 로고
    • In vivo evidence for lactate as a neuronal energy source
    • doi: 10.1523/JNEUROSCI.0415-11.2011
    • Wyss, M. T., Jolivet, R., Buck, A., Magistretti, P. J., and Weber, B. (2011). In vivo evidence for lactate as a neuronal energy source. J. Neurosci. 31, 7477-7485. doi: 10.1523/JNEUROSCI.0415-11.2011
    • (2011) J. Neurosci , vol.31 , pp. 7477-7485
    • Wyss, M.T.1    Jolivet, R.2    Buck, A.3    Magistretti, P.J.4    Weber, B.5
  • 55
    • 0033673044 scopus 로고    scopus 로고
    • NMR spectroscopic study on the metabolic fate of [3-(13)C]alanine in astrocytes, neurons, and cocultures: implications for glia-neuron interactions in neurotransmitter metabolism
    • doi: 10.1002/1098-1136(200012)32:3<286::AID-GLIA80>3.0.CO;2-P
    • Zwingmann, C., Richter-Landsberg, C., Brand, A., and Leibfritz, D. (2000). NMR spectroscopic study on the metabolic fate of [3-(13)C]alanine in astrocytes, neurons, and cocultures: implications for glia-neuron interactions in neurotransmitter metabolism. Glia 32, 286-303. doi: 10.1002/1098-1136(200012)32:3<286::AID-GLIA80>3.0.CO;2-P
    • (2000) Glia , vol.32 , pp. 286-303
    • Zwingmann, C.1    Richter-Landsberg, C.2    Brand, A.3    Leibfritz, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.