메뉴 건너뛰기




Volumn 32, Issue 1, 2013, Pages

Renal cancer-selective Englerin A induces multiple mechanisms of cell death and autophagy

Author keywords

Apoptosis; Autophagy; Englerin A; Necrosis; Renal cell carcinoma

Indexed keywords

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; AUTOPHAGY; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; KIDNEY NEOPLASMS; PHOSPHORYLATION; SESQUITERPENES, GUAIANE;

EID: 84884285360     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-32-57     Document Type: Article
Times cited : (35)

References (51)
  • 1
    • 33751032350 scopus 로고    scopus 로고
    • The evolving presentation of renal carcinoma in the united states: Trends from the surveillance, epidemiology, and end results program
    • DOI 10.1016/j.juro.2006.07.144, PII S0022534706019392
    • The evolving presentation of renal carcinoma in the United States: trends from the Surveillance, Epidemiology, and End Results program. Nguyen MM, Gill IS, Ellison LM, J Urol 2006 176 6 Pt 1 2397 400 17085111 (Pubitemid 44755062)
    • (2006) Journal of Urology , vol.176 , Issue.6 , pp. 2397-2400
    • Nguyen, M.M.1    Gill, I.S.2    Ellison, L.M.3
  • 2
    • 12344335787 scopus 로고    scopus 로고
    • Renal cell carcinoma: Review of novel single-agent therapeutics and combination regimens
    • DOI 10.1093/annonc/mdi002
    • Renal cell carcinoma: review of novel single-agent therapeutics and combination regimens. Amato RJ, Ann Oncol 2005 16 1 7 15 10.1093/annonc/mdi002 15598929 (Pubitemid 40124470)
    • (2005) Annals of Oncology , vol.16 , Issue.1 , pp. 7-15
    • Amato, R.J.1
  • 3
    • 33846477806 scopus 로고    scopus 로고
    • Targeted molecular therapy for renal cell carcinoma
    • DOI 10.1016/j.urology.2006.09.028, PII S0090429506021522
    • Targeted molecular therapy for renal cell carcinoma. Lane BR, Rini BI, Novick AC, Campbell SC, Urology 2007 69 1 3 10 17280906 (Pubitemid 46161691)
    • (2007) Urology , vol.69 , Issue.1 , pp. 3-10
    • Lane, B.R.1    Rini, B.I.2    Novick, A.C.3    Campbell, S.C.4
  • 4
    • 79955037961 scopus 로고    scopus 로고
    • Update on targeted therapies for clear cell renal cell carcinoma
    • 10.1097/CCO.0b013e32834479c0 21330923
    • Update on targeted therapies for clear cell renal cell carcinoma. Singer EA, Gupta GN, Srinivasan R, Curr Opin Oncol 2011 23 3 283 9 10.1097/CCO. 0b013e32834479c0 21330923
    • (2011) Curr Opin Oncol , vol.23 , Issue.3 , pp. 283-289
    • Singer, E.A.1    Gupta, G.N.2    Srinivasan, R.3
  • 7
    • 0028235907 scopus 로고
    • Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas
    • 8187067
    • Frequent somatic mutations and loss of heterozygosity of the von Hippel-Lindau tumor suppressor gene in primary human renal cell carcinomas. Shuin T, Kondo K, Torigoe S, Kishida T, Kubota Y, Hosaka M, Nagashima Y, Kitamura H, Latif F, Zbar B, et al. Cancer Res 1994 54 11 2852 5 8187067
    • (1994) Cancer Res , vol.54 , Issue.11 , pp. 2852-2855
    • Shuin, T.1    Kondo, K.2    Torigoe, S.3    Kishida, T.4    Kubota, Y.5    Hosaka, M.6    Nagashima, Y.7    Kitamura, H.8    Latif, F.9    Zbar, B.10
  • 8
    • 0033233243 scopus 로고    scopus 로고
    • 2 homeostasis by hypoxia-inducible factor 1
    • DOI 10.1146/annurev.cellbio.15.1.551
    • Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1. Semenza GL, Annu Rev Cell Dev Biol 1999 15 551 578 10.1146/annurev.cellbio.15.1. 551 10611972 (Pubitemid 32250386)
    • (1999) Annual Review of Cell and Developmental Biology , vol.15 , pp. 551-578
    • Semenza, G.L.1
  • 9
    • 34547125574 scopus 로고    scopus 로고
    • Hypoxia, gene expression, and metastasis
    • DOI 10.1007/s10555-007-9063-1, Special issue on Hypoxia and Cancer, Guest Editor: Gregg L. Semenza
    • Hypoxia, gene expression, and metastasis. Chan DA, Giaccia AJ, Cancer Metast Rev 2007 26 2 333 339 10.1007/s10555-007-9063-1 (Pubitemid 47101666)
    • (2007) Cancer and Metastasis Reviews , vol.26 , Issue.2 , pp. 333-339
    • Chan, D.A.1    Giaccia, A.J.2
  • 11
    • 70350064307 scopus 로고    scopus 로고
    • The role of VHL in clear-cell renal cell carcinoma and its relation to targeted therapy
    • 10.1038/ki.2009.296 19657325
    • The role of VHL in clear-cell renal cell carcinoma and its relation to targeted therapy. Clark PE, Kidney Int 2009 76 9 939 945 10.1038/ki.2009.296 19657325
    • (2009) Kidney Int , vol.76 , Issue.9 , pp. 939-945
    • Clark, P.E.1
  • 12
    • 84871773566 scopus 로고    scopus 로고
    • Novel agents in renal carcinoma: A reality check
    • 10.1177/1758834012443725 22754592
    • Novel agents in renal carcinoma: a reality check. Najjar YG, Rini BI, Ther Adv Med Oncol 2012 4 4 183 194 10.1177/1758834012443725 22754592
    • (2012) Ther Adv Med Oncol , vol.4 , Issue.4 , pp. 183-194
    • Najjar, Y.G.1    Rini, B.I.2
  • 13
    • 29044445562 scopus 로고    scopus 로고
    • Medicinal plants: Traditions of yesterday and drugs of tomorrow
    • DOI 10.1016/j.mam.2005.07.008, PII S0098299705000348
    • Medicinal plants: Traditions of yesterday and drugs of tomorrow. Gurib-Fakim A, Mol Aspects Med 2006 27 1 1 93 10.1016/j.mam.2005.07.008 16105678 (Pubitemid 41790645)
    • (2006) Molecular Aspects of Medicine , vol.27 , Issue.1 , pp. 1-93
    • Gurib-Fakim, A.1
  • 14
    • 84876002671 scopus 로고    scopus 로고
    • Natural products: A continuing source of novel drug leads
    • 10.1016/j.bbagen.2013.02.008 23428572
    • Natural products: A continuing source of novel drug leads. Cragg G, Newmann DJ, Biochim Biophys Acta 2013 1830 6 3670 95 10.1016/j.bbagen.2013.02. 008 23428572
    • (2013) Biochim Biophys Acta , vol.1830 , Issue.6 , pp. 3670-3695
    • Cragg, G.1    Newmann, D.J.2
  • 15
    • 0031870607 scopus 로고    scopus 로고
    • A review of the plants of the genus Phyllanthus: Their chemistry, pharmacology, and therapeutic potential
    • 10.1002/(SICI)1098-1128(199807)18:4<189: AID-MED1>3.0.CO;2-R 9664290
    • A review of the plants of the genus Phyllanthus: Their chemistry, pharmacology, and therapeutic potential. Calixto JB, Santos ARS, Filho VC, Yunes RA, Med Res Rev 1998 18 4 189 296 10.1002/(SICI)1098-1128(199807)18:4<189:: AID-MED1>3.0.CO;2-R 9664290
    • (1998) Med Res Rev , vol.18 , Issue.4 , pp. 189-296
    • Calixto, J.B.1    Santos, A.R.S.2    Filho, V.C.3    Yunes, R.A.4
  • 16
    • 59649114569 scopus 로고    scopus 로고
    • Englerin A, a selective inhibitor of renal cancer cell growth, from phyllanthus engleri
    • 10.1021/ol802339w 19061394
    • Englerin A, a selective inhibitor of renal cancer cell growth, from phyllanthus engleri. Ratnayake R, Covell D, Ransom TT, Gustafson KR, Beutler JA, Org Lett 2009 11 1 57 60 10.1021/ol802339w 19061394
    • (2009) Org Lett , vol.11 , Issue.1 , pp. 57-60
    • Ratnayake, R.1    Covell, D.2    Ransom, T.T.3    Gustafson, K.R.4    Beutler, J.A.5
  • 17
    • 77953982426 scopus 로고    scopus 로고
    • Total synthesis: Towards artificial terpene cyclases
    • 10.1038/nchem.715 20571563
    • Total synthesis: towards artificial terpene cyclases. Willot M, Christmann M, Nat Chem 2010 2 7 519 520 10.1038/nchem.715 20571563
    • (2010) Nat Chem , vol.2 , Issue.7 , pp. 519-520
    • Willot, M.1    Christmann, M.2
  • 18
    • 80455176963 scopus 로고    scopus 로고
    • Synthetic strategies toward the guaiane sesquiterpene englerin A
    • Synthetic strategies toward the guaiane sesquiterpene englerin A. Chain WJ, Synlett 2011 18 2605 2608
    • (2011) Synlett , vol.18 , pp. 2605-2608
    • Chain, W.J.1
  • 19
    • 84255169377 scopus 로고    scopus 로고
    • Chemical synthesis of the englerins
    • 10.1002/asia.201100780 22162365
    • Chemical synthesis of the englerins. Pouwer RH, Richard JA, Tseng CC, Chen DY, Chem Asian J 2012 7 1 22 35 10.1002/asia.201100780 22162365
    • (2012) Chem Asian J , vol.7 , Issue.1 , pp. 22-35
    • Pouwer, R.H.1    Richard, J.A.2    Tseng, C.C.3    Chen, D.Y.4
  • 20
    • 84860187174 scopus 로고    scopus 로고
    • Progresses in total synthesis of englerin A and biological evaluations of its analogues
    • 10.6023/cjoc1110141
    • Progresses in total synthesis of englerin A and biological evaluations of its analogues. Lu YY, Yao HQ, Sun BF, Chin J Org Chem 2012 32 1 1 12 10.6023/cjoc1110141
    • (2012) Chin J Org Chem , vol.32 , Issue.1 , pp. 1-12
    • Lu, Y.Y.1    Yao, H.Q.2    Sun, B.F.3
  • 21
    • 84860476423 scopus 로고    scopus 로고
    • Formal synthesis of (-)-englerin A and cytotoxicity studies of truncated englerins
    • 10.1002/asia.201101021 22415793
    • Formal synthesis of (-)-englerin A and cytotoxicity studies of truncated englerins. Xu J, Caro-Diaz EJ, Batova A, Sullivan SD, Theodorakis EA, Chem Asian J 2012 7 5 1052 60 10.1002/asia.201101021 22415793
    • (2012) Chem Asian J , vol.7 , Issue.5 , pp. 1052-1060
    • Xu, J.1    Caro-Diaz, E.J.2    Batova, A.3    Sullivan, S.D.4    Theodorakis, E.A.5
  • 22
    • 84867739753 scopus 로고    scopus 로고
    • Englerin A selectively induces necrosis in human renal cancer cells
    • 10.1371/journal.pone.0048032 23144724
    • Englerin A selectively induces necrosis in human renal cancer cells. Sulzmaier FJ, Li Z, Nakashige ML, Fash DM, Chain WJ, Ramos JW, PLoS One 2012 7 10 48032 10.1371/journal.pone.0048032 23144724
    • (2012) PLoS One , vol.7 , Issue.10 , pp. 548032
    • Sulzmaier, F.J.1    Li, Z.2    Nakashige, M.L.3    Fash, D.M.4    Chain, W.J.5    Ramos, J.W.6
  • 24
    • 4444317848 scopus 로고    scopus 로고
    • Regulation of Vinca alkaloid-induced apoptosis by NF-κB/IκB pathway in human tumor cells
    • Regulation of Vinca alkaloid-induced apoptosis by NF-κB/IκB pathway in human tumor cells. Huang Y, Fang Y, Wu J, Dziadyk JM, Zhu X, Sui M, Fan W, Mol Cancer Ther 2004 3 3 271 277 15026547 (Pubitemid 39193702)
    • (2004) Molecular Cancer Therapeutics , vol.3 , Issue.3 , pp. 271-277
    • Huang, Y.1    Fang, Y.2    Wu, J.3    Dziadyk, J.4    Zhu, X.5    Sui, M.6    Fan, W.7
  • 25
    • 3242675057 scopus 로고    scopus 로고
    • Association of active caspase 8 with the mitochondrial membrane during apoptosis: Potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death
    • DOI 10.1128/MCB.24.15.6592-6607.2004
    • Association of active caspase 8 with the mitochondrial membrane during apoptosis: potential roles in cleaving BAP31 and caspase 3 and mediating mitochondrion-endoplasmic reticulum cross talk in etoposide-induced cell death. Chandra D, Choy G, Deng X, Bhatia B, Daniel P, Tang DG, Mol Cell Biol 2004 24 15 6592 607 10.1128/MCB.24.15.6592-6607.2004 15254227 (Pubitemid 38944340)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.15 , pp. 6592-6607
    • Chandra, D.1    Choy, G.2    Deng, X.3    Bhatia, B.4    Daniel, P.5    Tang, D.G.6
  • 26
    • 2942616456 scopus 로고    scopus 로고
    • 2- and p53-dependent pathways
    • DOI 10.1074/jbc.M400944200
    • Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms: intermediacy of H(2)O(2)- and p53-dependent pathways. Wang S, Konorev EA, Kotamraju S, Joseph J, Kalivendi S, Kalyanaraman B, J Biol Chem 2004 279 24 25535 43 10.1074/jbc.M400944200 15054096 (Pubitemid 38756813)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.24 , pp. 25535-25543
    • Wang, S.1    Konorev, E.A.2    Kotamraju, S.3    Joseph, J.4    Kalivendi, S.5    Kalyanaraman, B.6
  • 27
    • 12344305300 scopus 로고    scopus 로고
    • Camptothecin- and etoposide-induced apoptosis in human leukemia cells is independent of cell death receptor-3 and -4 aggregation but accelerates tumor necrosis factor-related apoptosis-inducing ligand-mediated cell death
    • Camptothecin- and etoposide-induced apoptosis in human leukemia cells is independent of cell death receptor-3 and -4 aggregation but accelerates tumor necrosis factor-related apoptosis-inducing ligand-mediated cell death. Bergeron S, Beauchemin M, Bertrand R, Mol Cancer Ther 2004 3 12 1659 69 15634660 (Pubitemid 40136722)
    • (2004) Molecular Cancer Therapeutics , vol.3 , Issue.12 , pp. 1659-1669
    • Bergeron, S.1    Beauchemin, M.2    Bertrand, R.3
  • 29
    • 70349750492 scopus 로고    scopus 로고
    • Rapamycin protects against rotenone-induced apoptosis through autophagy induction
    • 10.1016/j.neuroscience.2009.08.014 19682553
    • Rapamycin protects against rotenone-induced apoptosis through autophagy induction. Pan T, Rawal P, Wu Y, Xie W, Jankovic J, Le W, Neuroscience 2009 164 2 541 51 10.1016/j.neuroscience.2009.08.014 19682553
    • (2009) Neuroscience , vol.164 , Issue.2 , pp. 541-551
    • Pan, T.1    Rawal, P.2    Wu, Y.3    Xie, W.4    Jankovic, J.5    Le, W.6
  • 30
    • 84878977228 scopus 로고    scopus 로고
    • Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway
    • 10.1093/carcin/bgt060 23393227
    • Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway. Zhang DM, Liu JS, Deng LJ, Chen MF, Yiu A, Cao HH, Tian HY, Fung KP, Kurihara H, Pan JX, Ye WC, Carcinogenesis 2013 34 6 1331 42 10.1093/carcin/bgt060 23393227
    • (2013) Carcinogenesis , vol.34 , Issue.6 , pp. 1331-1342
    • Zhang, D.M.1    Liu, J.S.2    Deng, L.J.3    Chen, M.F.4    Yiu, A.5    Cao, H.H.6    Tian, H.Y.7    Fung, K.P.8    Kurihara, H.9    Pan, J.X.10    Ye, W.C.11
  • 32
    • 3242888703 scopus 로고    scopus 로고
    • LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
    • DOI 10.1242/jcs.01131
    • LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. Kabeya Y, Mizushima N, Yamamoto A, Oshitani-Okamoto S, Ohsumi Y, Yoshimori T, J Cell Sci 2004 117 Pt 13 2805 12 15169837 (Pubitemid 38997262)
    • (2004) Journal of Cell Science , vol.117 , Issue.13 , pp. 2805-2812
    • Kabeya, Y.1    Mizushima, N.2    Yamamoto, A.3    Oshitani-Okamoto, S.4    Ohsumi, Y.5    Yoshimori, T.6
  • 33
    • 84934444765 scopus 로고    scopus 로고
    • Amino acid regulation of autophagosome formation
    • 10.1007/978-1-59745-157-4-5 18425444
    • Amino acid regulation of autophagosome formation. Meijer AJ, Methods Mol Biol 2008 445 89 109 10.1007/978-1-59745-157-4-5 18425444
    • (2008) Methods Mol Biol , vol.445 , pp. 89-109
    • Meijer, A.J.1
  • 34
    • 1542289063 scopus 로고    scopus 로고
    • Amino Acids and Insulin Control Autophagic Proteolysis through Different Signaling Pathways in Relation to mTOR in Isolated Rat Hepatocytes
    • DOI 10.1074/jbc.M306337200
    • Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes. Kanazawa T, Taneike I, Akaishi R, Yoshizawa F, Furuya N, Fujimura S, Kadowaki M, J Biol Chem 2004 279 9 8452 9 14610086 (Pubitemid 38294738)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.9 , pp. 8452-8459
    • Kanazawa, T.1    Taneike, I.2    Akaishi, R.3    Yoshizawa, F.4    Furuya, N.5    Fujimura, S.6    Kadowaki, M.7
  • 35
    • 84862295360 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy
    • 10.4161/auto.19496 22966490
    • Guidelines for the use and interpretation of assays for monitoring autophagy. Klionsky DJ, Abdalla FC, Abeliovich H, et al. Autophagy 2012 8 4 445 544 10.4161/auto.19496 22966490
    • (2012) Autophagy , vol.8 , Issue.4 , pp. 445-544
    • Klionsky, D.J.1    Abdalla, F.C.2    Abeliovich, H.3
  • 36
    • 77951217000 scopus 로고    scopus 로고
    • Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class i and III phosphoinositide 3-kinase
    • 10.1074/jbc.M109.080796 20123989
    • Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. Wu YT, Tan HL, Shui G, Bauvy C, Huang Q, Wenk MR, Ong CN, Codogno P, Shen HM, J Biol Chem 2010 285 14 10850 61 10.1074/jbc.M109.080796 20123989
    • (2010) J Biol Chem , vol.285 , Issue.14 , pp. 10850-10861
    • Wu, Y.T.1    Tan, H.L.2    Shui, G.3    Bauvy, C.4    Huang, Q.5    Wenk, M.R.6    Ong, C.N.7    Codogno, P.8    Shen, H.M.9
  • 37
    • 77954296394 scopus 로고    scopus 로고
    • 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors
    • 10.1016/j.ccr.2010.05.023 20609351
    • 4E-BP1 is a key effector of the oncogenic activation of the AKT and ERK signaling pathways that integrates their function in tumors. She QB, Halilovic E, Ye Q, Zhen W, Shirasawa S, Sasazuki T, Solit DB, Rosen N, Cancer Cell 2010 18 1 39 51 10.1016/j.ccr.2010.05.023 20609351
    • (2010) Cancer Cell , vol.18 , Issue.1 , pp. 39-51
    • She, Q.B.1    Halilovic, E.2    Ye, Q.3    Zhen, W.4    Shirasawa, S.5    Sasazuki, T.6    Solit, D.B.7    Rosen, N.8
  • 38
    • 34347238938 scopus 로고    scopus 로고
    • Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: Role of akt and extracellular signal-regulated kinase signaling pathways
    • DOI 10.1124/mol.106.033167
    • Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. Aoki H, Takada Y, Kondo S, Sawaya R, Aggarwal BB, Kondo Y, Mol Pharmacol 2007 72 1 29 39 10.1124/mol.106.033167 17395690 (Pubitemid 46998522)
    • (2007) Molecular Pharmacology , vol.72 , Issue.1 , pp. 29-39
    • Aoki, H.1    Takada, Y.2    Kondo, S.3    Sawaya, R.4    Aggarwal, B.B.5    Kondo, Y.6
  • 39
    • 80053035284 scopus 로고    scopus 로고
    • AMP-activated protein kinase: An energy sensor that regulates all aspects of cell function
    • 10.1101/gad.17420111 21937710
    • AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. Hardie DG, Genes Dev 2011 25 18 1895 908 10.1101/gad.17420111 21937710
    • (2011) Genes Dev , vol.25 , Issue.18 , pp. 1895-1908
    • Hardie, D.G.1
  • 40
    • 84859869957 scopus 로고    scopus 로고
    • Renal cancer: Oxygen meets metabolism
    • 10.1016/j.yexcr.2012.02.026 22406000
    • Renal cancer: Oxygen meets metabolism. Volker HH, Exp Cell Res 2012 318 9 1057 67 10.1016/j.yexcr.2012.02.026 22406000
    • (2012) Exp Cell Res , vol.318 , Issue.9 , pp. 1057-1067
    • Volker, H.H.1
  • 41
    • 0018927246 scopus 로고
    • Amino acid inhibition of the autophagic/lysosomal pathway of protein degradation in isolated rat hepatocytes
    • 10.1016/0304-4165(80)90141-5 7388042
    • Amino acid inhibition of the autophagic/lysosomal pathway of protein degradation in isolated rat hepatocytes. Seglen PO, Gordon PB, Poli A, Biochim Biophys Acta 1980 630 1 103 1 10.1016/0304-4165(80)90141-5 7388042
    • (1980) Biochim Biophys Acta , vol.630 , Issue.1 , pp. 103-111
    • Seglen, P.O.1    Gordon, P.B.2    Poli, A.3
  • 42
    • 84863954409 scopus 로고    scopus 로고
    • Regulation and function of autophagy during cell survival and cell death
    • 10.1101/cshperspect.a008813 22661635
    • Regulation and function of autophagy during cell survival and cell death. Das G, Shravage BV, Baehrecke EH, Cold Spring Harb Perspect Biol 2012 4 6 008813 10.1101/cshperspect.a008813 22661635
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , Issue.6 , pp. 1008813
    • Das, G.1    Shravage, B.V.2    Baehrecke, E.H.3
  • 43
    • 84866104515 scopus 로고    scopus 로고
    • Metabolic stress in autophagy and cell death pathways
    • 10.1101/cshperspect.a008763 22952396
    • Metabolic stress in autophagy and cell death pathways. Altman BJ, Rathmell JC, Cold Spring Harb Perspect Biol 2012 4 9 008763 10.1101/cshperspect. a008763 22952396
    • (2012) Cold Spring Harb Perspect Biol , vol.4 , Issue.9 , pp. 1008763
    • Altman, B.J.1    Rathmell, J.C.2
  • 44
    • 84864960912 scopus 로고    scopus 로고
    • Autophagy, stress, and cancer metabolism: What doesn't kill you makes you stronger
    • 10.1101/sqb.2012.76.011015 22442109
    • Autophagy, stress, and cancer metabolism: what doesn't kill you makes you stronger. Mathew R, White E, Cold Spring Harb Symp Quant Biol 2011 76 389 96 10.1101/sqb.2012.76.011015 22442109
    • (2011) Cold Spring Harb Symp Quant Biol , vol.76 , pp. 389-396
    • Mathew, R.1    White, E.2
  • 45
    • 79960920096 scopus 로고    scopus 로고
    • Inhibition of active autophagy induces apoptosis and increases chemosensitivity in cholangiocarcinoma
    • 10.1038/labinvest.2011.97 21647092
    • Inhibition of active autophagy induces apoptosis and increases chemosensitivity in cholangiocarcinoma. Hou YJ, Dong LW, Tan YX, Yang GZ, Pan YF, Li Z, Tang L, Wang M, Wang Q, Wang HY, Lab Invest 2011 91 8 1146 57 10.1038/labinvest.2011.97 21647092
    • (2011) Lab Invest , vol.91 , Issue.8 , pp. 1146-1157
    • Hou, Y.J.1    Dong, L.W.2    Tan, Y.X.3    Yang, G.Z.4    Pan, Y.F.5    Li, Z.6    Tang, L.7    Wang, M.8    Wang, Q.9    Wang, H.Y.10
  • 46
    • 0033047235 scopus 로고    scopus 로고
    • Apoptosis without caspases: An inefficient molecular guillotine?
    • Apoptosis without caspases: an inefficient molecular guillotine? Borner C, Monney L, Cell Death Differ 1999 6 6 497 507 10.1038/sj.cdd.4400525 10381652 (Pubitemid 29292105)
    • (1999) Cell Death and Differentiation , vol.6 , Issue.6 , pp. 497-507
    • Borner, C.1    Monney, L.2
  • 49
    • 77955947900 scopus 로고    scopus 로고
    • Linking ER stress to autophagy: Potential implications for cancer therapy
    • 20145727
    • Linking ER Stress to Autophagy: Potential Implications for Cancer Therapy. Verfaillie T, Salazar M, Velasco G, Agostinis P, Int J Cell Biol 2010 2010 930509 20145727
    • (2010) Int J Cell Biol , vol.2010 , pp. 930509
    • Verfaillie, T.1    Salazar, M.2    Velasco, G.3    Agostinis, P.4
  • 50
    • 45849147350 scopus 로고    scopus 로고
    • A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy
    • DOI 10.1016/j.ccr.2008.06.004, PII S1535610808001943
    • A molecule targeting VHL-deficient renal cell carcinoma that induces autophagy. Turcotte S, Chan DA, Sutphin PD, Hay MP, Denny WA, Giaccia AJ, Cancer Cell 2008 14 1 90 102 10.1016/j.ccr.2008.06.004 18598947 (Pubitemid 351885499)
    • (2008) Cancer Cell , vol.14 , Issue.1 , pp. 90-102
    • Turcotte, S.1    Chan, D.A.2    Sutphin, P.D.3    Hay, M.P.4    Denny, W.A.5    Giaccia, A.J.6
  • 51
    • 78651386350 scopus 로고    scopus 로고
    • Carminomycin i is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells
    • 10.1158/0008-5472.CAN-10-0757 21199801
    • Carminomycin I is an apoptosis inducer that targets the Golgi complex in clear cell renal carcinoma cells. Woldemichael GM, Turbyville TJ, Linehan WM, McMahon JB, Cancer Res 2011 71 1 134 42 10.1158/0008-5472.CAN-10-0757 21199801
    • (2011) Cancer Res , vol.71 , Issue.1 , pp. 134-142
    • Woldemichael, G.M.1    Turbyville, T.J.2    Linehan, W.M.3    McMahon, J.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.