An ER-peroxisome tether exerts peroxisome population control in yeast

EMBO Journal

Volumn 32, Issue 18, 2013, Pages 2439-2453

  Knoblach, Barbara ^a   Sun, Xuejun ^a   Coquelle, Nicolas ^a   Fagarasanu, Andrei ^a   Poirier, Richard L ^a   Rachubinski, Richard A ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Endoplasmic reticulum; Organelle inheritance; Organelle tether; Peroxisome; Protein complex

Indexed keywords

PEROXIN;

ARTICLE; DAUGHTER CELL; ENDOPLASMIC RETICULUM; EUKARYOTIC CELL; INHERITANCE; NONHUMAN; PEROXISOME; POPULATION DYNAMICS; PRIORITY JOURNAL; PROTEIN INTERACTION; SACCHAROMYCES CEREVISIAE;

CELL DIVISION; ENDOPLASMIC RETICULUM; MEMBRANE PROTEINS; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MUTATION; PEROXISOMES; PROTEIN CONFORMATION; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 84884284362     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.170     Document Type: Article

References (31)

1. Agrawal G, Joshi S, Subramani S (2011) Cell-free sorting of peroxisomal membrane proteins from the endoplasmic reticulum. Proc Natl Acad Sci USA 108: 9113-9118
2. Chang J, Mast FD, Fagarasanu A, Rachubinski DA, Eitzen GA, Dacks JB, Rachubinski RA (2009) Pex3 peroxisome biogenesis proteins function in peroxisome inheritance as class V myosin receptors. J Cell Biol 187: 233-246
3. Fagarasanu A, Fagarasanu M, Eitzen GA, Aitchison JD, Rachubinski RA (2006) The peroxisomal membrane protein Inp2p of the peroxisomespecific receptor for the myosin V motor Myo2p of Saccharomyces cerevisiae. Dev Cell 10: 587-600
4. Fagarasanu A, Mast FD, Knoblach B, Jin Y, Brunner MJ, Logan MR, Glover JN, Eitzen GA, Aitchison JD, Weisman LS, Rachubinski RA (2009) Myosin-driven peroxisome partitioning in S. cerevisiae. J Cell Biol 186: 541-554
5. Fagarasanu A, Mast FD, Knoblach B, Rachubinski RA (2010) Molecular mechanisms of organelle inheritance: lessons from peroxisomes in yeast. Nat Rev Mol Cell Biol 11: 644-654
6. Fagarasanu M, Fagarasanu A, Tam YYC, Aitchison JD, Rachubinski RA (2005) Inp1p is a peroxisomal membrane protein required for peroxisome inheritance in Saccharomyces cerevisiae. J Cell Biol 169: 765-775
7. Fang Y, Morrell JC, Jones JM, Gould SJ (2004) PEX3 functions as a PEX19 docking factor in the import of class I peroxisomal membrane proteins. J Cell Biol 164: 863-875
8. Götte K, Girzalsky W, Linkert M, Baumgart E, Kammerer S, Kunau WH, Erdmann R (1998) Pex19p, a farnesylated protein essential for peroxisome biogenesis. Mol Cell Biol 18: 616-628
9. Hettema EH, Girzalsky W, van den Berg M, Erdmann R, Distel B (2000) Saccharomyces cerevisiae Pex3p and Pex19p are required for proper localization and stability of peroxisomal membrane proteins. EMBO J 19: 223-233
10. Hoepfner D, Schildknegt D, Braakman I, Philippsen P, Tabak HF (2005) Contribution of the endoplasmic reticulum to peroxisome formation. Cell 122: 85-95
11. Hoepfner D, van den Berg M, Phillipsen P, Tabak HF, Hettema EH (2001) A role for Vps1p, actin, and the Myo2p motor in peroxisome abundance and inheritance in Saccharomyces cerevisiae. J Cell Biol 155: 979-990
12. Kim PK, Mullen RT, Schumann U, Lippincott-Schwartz J (2006) The origin and maintenance of mammalian peroxisomes involves a de novo PEX16-dependent pathway from the ER. J Cell Biol 173: 521-532
13. Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P (2009) An ER-mitochondria tethering complex revealed by a synthetic biology screen. Science 325: 477-481
14. Kuravi K, Nagotu S, Krikken AM, Sjollema K, Deckers M, Erdmann R, Veenhuis M, van der Klei IJ (2006) Dynamin-related proteins Vps1p and Dnm1p control peroxisome abundance in Saccharomyces cerevisiae. J Cell Sci 119: 3994-4001
15. Lam SK, Yoda N, Schekman R (2011) A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum. Proc Natl Acad Sci USA 107: 21523-21528
16. Motley AM, Hettema EH (2007) Yeast peroxisomes multiply by growth and division. J Cell Biol 178: 399-410
17. Munck JM, Motley AM, Nuttall JM, Hettema EH (2009) A dual function for Pex3p in peroxisome formation and inheritance. J Cell Biol 187: 463-471
18. Sato Y, Shibata H, Nakano H, Matsuzono Y, Kashiwayama Y, Kobayashi Y, Fujiki Y, Imanaka T, Kato H (2008) Characterization of the interaction between recombinant human peroxin Pex3p and Pex19p: identification of TRP-104 in Pex3p as a critical residue for the interaction. J Biol Chem 283: 6136-6144
19. Sato Y, Shibata H, Nakatsu T, Nakano H, Kashiwayama Y, Imanaka T, Kato H (2010) Structural basis for docking of peroxisomal membrane protein carrier Pex19p onto its receptor Pex3p. EMBO J 29: 4083-4093
20. Schekman R (2005) Peroxisomes: another branch of the secretory pathway? Cell 122: 1-2
21. Schmidt F, Treiber N, Zocher G, Bjelic S, Steinmetz MO, Kalbacher H, Stehle T, Dodt G (2010) Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19. J Biol Chem 285: 25410-25417
22. Storici F, Lewis LK, Resnick MA (2001) In vivo site-directed mutagenesis using oligonucleotides. Nat Biotech 19: 773-776
23. Tam YYC, Fagarasanu A, Fagarasanu M, Rachubinski RA (2005) Pex3p initiates the formation of a preperoxisomal compartment from a subdomain of the endoplasmic reticulum in Saccharomyces cerevisiae. J Biol Chem 280: 34933-34939
24. Thoms S, Harms I, Kalies KU, Gartner J (2012) Peroxisome formation requires the endoplasmic reticulum channel protein Sec61. Traffic 13: 599-609
25. Titorenko VI, Chan H, Rachubinski RA (2000) Fusion of small peroxisomal vesicles in vitro reconstructs an early step in the in vivo multistep peroxisome assembly pathway of Yarrowia lipolytica. J Cell Biol 148: 29-44
26. Titorenko VI, Rachubinski RA (1998) Mutants of the yeast Yarrowia lipolytica defective in protein exit from the endoplasmic reticulum are also defective in peroxisome biogenesis. Mol Cell Biol 18: 2789-2803
27. van der Zand A, Braakman I, Tabak HF (2010) Peroxisomal membrane proteins insert into the endoplasmic reticulum. Mol Biol Cell 21: 2057-2065
28. van der Zand A, Gent J, Braakman I, Tabak HF (2012) Biochemically distinct vesicles from the endoplasmic reticulum fuse to form peroxisomes. Cell 149: 397-409
29. West M, Zurek N, Hoenger A, Voeltz GK (2011) A 3D analysis of yeast ER structure reveals how ER domains are organized by membrane curvature. J Cell Biol 193: 333-346
30. Wilson CG, Magliery TJ, Regan L (2004) Detecting protein-protein interactions with GFP-fragment reassembly. Nat Methods 1: 255-262
31. Yan M, Rachubinski DA, Joshi S, Rachubinski RA, Subramani S (2008) Dysferlin domain-containing proteins, Pex30p and Pex31p, localized to two compartments, control the number and size of oleate-induced peroxisomes in Pichia pastoris. Mol Biol Cell 19: 885-898