A role for Vps1p, actin, and the Myo2p motor in peroxisome abundance and inheritance in Saccharomyces cerevisiae

Journal of Cell Biology

Volumn 155, Issue 6, 2001, Pages 979-990

  Hoepfner, Dominic ^a   Van Den Berg, Marlene ^b   Philippsen, Peter ^a   Tabak, Henk F ^b   Hettema, Ewald H ^b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Actin cytoskeleton; Fission; Myo2p; Peroxisome inheritance; Vps1

Indexed keywords

ACTIN; DYNAMIN; MYO2P PROTEIN; MYOD1 PROTEIN; MYOSIN; PROTEIN VPS1P; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ALLELE; ARTICLE; CELL BUDDING; CELL ORGANELLE; CHROMOSOME SEGREGATION; CYTOKINESIS; CYTOSKELETON; DELETION MUTANT; DEPOLYMERIZATION; EUKARYOTIC CELL; GOLGI COMPLEX; HEAT SENSITIVITY; MICROTUBULE; MOLECULAR DYNAMICS; NONHUMAN; PEROXISOME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SACCHAROMYCES CEREVISIAE;

ACTINS; BACTERIAL PROTEINS; BASE SEQUENCE; CARRIER PROTEINS; CYTOSKELETAL PROTEINS; GENE DELETION; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEINS; INDICATORS AND REAGENTS; LUMINESCENT PROTEINS; MEMBRANE PROTEINS; MICROFILAMENTS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MYOSIN HEAVY CHAINS; MYOSIN TYPE V; OLIGONUCLEOTIDE PROBES; PEROXISOMES; POLYMERS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0035842904     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200107028     Document Type: Article

References (91)

1. Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic mutant Saccharomyces cerevisiae
2. Three-dimensional imaging of the yeast actin cytoskeleton through the budding cell cycle
3. The role of the proteins Kar9 and Myo2 in orienting the mitotic spindle of budding yeast
4. Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells
5. What are the basic functions of microfilaments? Insights from studies in budding yeast
6. Pexl4p is a member of the protein linkage map of Pex5p
7. Myosins in yeast
8. XLI-Blue: A high efficiency plasmid transforming recA Escherichia coli strain with selection
9. Cytology of the yeast life cycle
10. Behaviour of spindle and spindle plaques in the cell cycle and conjugation of Saccharomyces cerevisiae
11. Microtubules orient the mitotic spindle through dynein-dependent interactions with the cell cortex
12. The terminal tail region of a yeast myosin-V mediates its attachment to vacuole membranes and sires of polarized growth
13. Divide and multiply: Organelle partitioning in yeast
14. The yeast spindle pole body component Spc72p interacts with Stu2p and is required for proper microtubuli assembly
15. Brain myosin-V is a two-headed unconventional myosin with motor activity
16. Inhibition of actin polymerization by latrunculin A
17. Movement of yeast cortical actin cytoskeleton visualized in vivo
18. Peroxisomes: Organelles at the crossroads
19. Cellular morphogenesis in the Saccharomyces cerevisiae cell cycle: Localization of the CDC11 gene product and the timing of the events at the budding site
20. The role of Myo2, a yeast class V myosin, in vesicular transport
21. Guide to yeast genetics and molecular biology
22. The cytosolic DnaJ-like protein Djp1p is involved specifically in peroxisomal protein import
23. Import of proteins into peroxisomes
24. Saccharomyces cerevisiae Pex3p and Pexl9p are required for proper localization and stability of peroxisomal membrane proteins
25. Mitotic motors in Saccharomyces cerevisiae
26. Actin and myosin function in directed vacuoic movement during cell division in Saccharomyces cerevisiae
27. Time-lapse video microscopy reveals astral microtubule detachment in the yeast spindle pole mutant cnm67
28. Ultrastructural analysis of hyphal tip cell growth in the spitzenkorper, cytoskeleton and endomembranes after freeze-substitution
29. Cytoplasmic microtubules and fungal morphogenesis: Ultrastructural effects of methyl benzimidazole-2-yl carbamate determined by freeze-substitution of hyphal tip cells
30. Rapid assessment of S. cerevisiae mating type by PCR
31. Functions of microtubules in the Saccharomyces cerevisiae cell cycle
32. The Saccharomyces cerevisiae MY02 gene encodes an essential myosin for vectorial transport of vesicles
33. Proteinase mutants of Saccrharomyces cerevzsiae
34. Role of actin and Myo2p in polarized secretion and growth of Saccharomyces cerevisiae
35. Structural rearrangements of tubulin and actin during the life cycle of the yeast Saccharomyces cerevisiae
36. Receptors determine the cellular localization of a gamma-tubulin complex and thereby the site of microtubule formation
37. Biogenesis of peroxisomes
38. Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA
39. Cell polarity and morphogenesis in yeast
40. Intermediate filament formation by a yeast protein essential for organelle inheritance
41. Microtubule polarity confers directions to pigment transport in chromarophores
42. The dynamin family of mechanoenzymes: Pinching in new places
43. Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome
44. Labeling of peroxisomes with green fluorescent protein in living P. pastoris cells
45. Dnmlp GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fislp
46. Regulation of organelle biogenesis
47. The dynamin-related GTPase, Dnmlp, controls mitochondrial morphology in yeast
48. Role of astral microtubules and actin in spindle orientation and migration in the budding yeast, Saccharomyces cerevisiae
49. Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va gene
50. Peroxisomal biogenesis: Multiple pathways of protein import
51. Microtubule-mediated peroxisoma saltations
52. Class V myosins
53. Microtubule-acting drugs lead to the nonpolarized delivery of the influenza hemagglutinin to the cell surface of polarized Madin-Darby canine kidney cells
54. Effect on microtubule assembly status on the intracellular processing and surface expression of an integral protein of the plasma membrane
55. A role for actin, Cdclp, and Myo2p in the inheritance of late Golgi elements in Saccharomyces cerevisiae
56. A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting
57. Targeting of chitin synthase 3 to polarized growth sites in yeast requires Chs5p and Myo2p
58. High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier
59. Mechanisms of intracellular organelle transport
60. The COOH-terminal domain of Myo2, a yeast myosin V, has a direct role in secretory vesicle targeting
61. Myosins: A diverse superfamily
62. Division versus fusion: Dnmlp and Fzolp antagonistically regulate mitochondrial shape
63. Astral microtubule dynamics in yeast: A microtubule-based searching mechanism for spindle orientation and nuclear migration into the bud
64. The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance
65. SPC72: A spindle pole component required for spindle orientation in the yeast Saccharomyces cerevisiae
66. Organelle transport and molecular motors in fungi
67. Mitosis in living yeast: Anaphase A but not metaphase plate
68. Import of peroxisomal matrix and membrane proteins
69. Astral microtubules are not required for anaphase B in Saccharomyces cerevisiae
70. Peroxisomes: Simple in function but complex in maintenance
71. Actin-dependent localization of an RNA encoding a cell-fate determinant in yeast
72. Mdv1p is a WD repeat protein that interacts with the dynamin-related GTPase, Dnm1p, to trigger mitochondrial division
73. Yeast Bim1p promotes the G1-spcific dynamics of microtubules
74. The endoplasmic reticulum plays an essential role in peroxisome biogenesis
75. Functional diversity in the dynamin family
76. A mitochondrial division apparatus takes shape
77. Biochemistry of peroxisomes
78. Kinesin: Possible biological roles for a new microtubule motor
79. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
80. Movement of cortical actin patches in yeast
81. Organelle Inheritance
82. Mutants of Saccharomyces cerevisiae that block intervacuole vesicular traffic and vacuole division and segregation
83. Visualization of the paroxysmal compartment in living mammalian cells - Dynamic behavior and association with microtubules
84. Vpslp, a member of the dynamin GTPase family, is necessary for Golgi membrane protein retention in Saccharomyces cerevisiae
85. A mutation in Rab27a causes the vesicle transport defects observed in ashen mice
86. The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria
87. Thioredoxin is required for vacuole inheritance in Saccharomyces cerevisiae
88. A retention mechanism for distribution of mitochondria during cell division in budding yeast
89. Dynamic mitochondria
90. Myosin V orientates the mitotic spindle in yeast