CD49b-dependent establishment of T helper cell memory

Immunology and Cell Biology

Volumn 91, Issue 8, 2013, Pages 524-531

  Hanazawa, Asami ^a,b   Hayashizaki, Koji ^a   Shinoda, Kenta ^a   Yagita, Hideo ^c   Okumura, Ko ^c   Löhning, Max ^b   Hara, Takahiro ^d   Tani Ichi, Shizue ^d   Ikuta, Koichi ^d   Eckes, Beate ^e   Radbruch, Andreas ^b   Tokoyoda, Koji ^a,b   Nakayama, Toshinori ^a,f  

^a CHIBA UNIVERSITY   (Japan)

^b German Rheumatism Research Center Berlin   (Germany)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Bone marrow; CD49b; Collagen; Immunological memory; Niche; T helper cell memory

Indexed keywords

ALPHA2 INTEGRIN; COLLAGEN TYPE 2; INTERLEUKIN 7;

ANIMAL CELL; ANTIGEN SPECIFICITY; ARTICLE; BONE MARROW; CD4+ T LYMPHOCYTE; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; HELPER CELL; IMMUNE RESPONSE; IMMUNOLOGICAL MEMORY; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; STROMA CELL;

RUMEX;

ANIMALS; ANTIGENS, CD4; BONE MARROW; CELL COMMUNICATION; CELL DIFFERENTIATION; CELL MOVEMENT; CELLS, CULTURED; COLLAGEN TYPE II; COLLAGEN TYPE XI; IMMUNOLOGIC MEMORY; INTEGRIN ALPHA2; INTERLEUKIN-7; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PRECURSOR CELLS, T-LYMPHOID; STROMAL CELLS; T-LYMPHOCYTES, HELPER-INDUCER; TRANSENDOTHELIAL AND TRANSEPITHELIAL MIGRATION;

EID: 84884281884     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2013.36     Document Type: Article

References (27)

1. Crotty S, Kersh EN, Cannons J, Schwartzberg PL, Ahmed R. SAP is required for generating long-term humoral immunity. Nature 2003; 421: 282-287.
2. Shedlock DJ, Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003; 300: 337-339.
3. Janssen EM, Lemmens EE, Wolfe T, Christen U, von Herrath MG, Schoenberger SP. CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature 2003; 421: 852-856.
4. Sun JC, Williams MA, Bevan MJ. CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection. Nat Immunol 2004; 5: 927-933.
5. Nakayama T, Yamashita M. Critical role of the Polycomb and Trithorax complexes in the maintenance of CD4 T cell memory. Semin Immunol 2009; 21: 78-83.
6. Kondrack RM, Harbertson J, Tan JT, McBreen ME, Surh CD, Bradley LM. Interleukin regulates the survival and generation of memory CD4 cells. J Exp Med 2003; 198: 1797-1806.
7. Li J, Huston G, Swain SL. IL-7 promotes the transition of CD4 effectors to persistent memory cells. J Exp Med 2003; 198: 1807-1815.
8. Tokoyoda K, Zehentmeier S, Hegazy AN, Albrecht I, Grün JR, Löhning M et al. Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow. Immunity 2009; 30: 721-730.
9. DeNucci CC, Shimizu Y. beta1 integrin is critical for the maintenance of antigenspecific CD4 T cells in the bone marrow but not long-term immunological memory. J Immunol 2011; 186: 4019-4026.
10. Herndler-Brandstetter D, Landgraf K, Tzankov A, Jenewein B, Brunauer R, Laschober GT et al. The impact of aging on memory T cell phenotype and function in the human bone marrow. J Leukoc Biol 2012; 91: 197-205.
11. Shinoda K, Tokoyoda K, Hanazawa A, Hayashizaki K, Zehentmeier S, Hosokawa H et al. Type II membrane protein CD69 regulates the formation of resting T-helper memory. Proc Natl Acad Sci USA 2012; 109: 7409-7414.
12. Hynes RO. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 1992; 69: 11-25.
13. Richter M, Ray SJ, Chapman TJ, Austin SJ, Rebhahn J, Mosmann TR et al. Collagen distribution and expression of collagen-binding alpha1beta1 (VLA-1) and alpha2beta1 (VLA-2) integrins on CD4 and CD8 T cells during influenza infection. J Immunol 2007; 178: 4506-4516.
14. Shoulders MD, Raines RT. Collagen structure and stability. Annu Rev Biochem 2009; 78: 929-958.
15. Heino J. The collagen family members as cell adhesion proteins. Bioessays 2007; 29: 1001-1010.
16. Kern A, Eble J, Golbik R, Kuhn K. Interaction of type IV collagen with the isolated integrins alpha 1 beta 1 and alpha 2 beta 1. Eur J Biochem 1993; 215: 151-159.
17. Tuckwell D, Calderwood DA, Green LJ, Humphries MJ. Integrin alpha 2 I-domain is a binding site for collagens. J Cell Sci 1995; 108 (Pt 4), 1629-1637.
18. Friedl P, Noble PB, Zanker KS. T lymphocyte locomotion in a three-dimensional collagen matrix. Expression and function of cell adhesion molecules. J Immunol 1995; 154: 4973-4985.
19. Ariel A, Hershkoviz R, Cahalon L, Williams DE, Akiyama SK, Yamada KM et al. Induction of T cell adhesion to extracellular matrix or endothelial cell ligands by soluble or matrix-bound interleukin-7. Eur J Immunol 1997; 27: 2562-2570.
20. Kassiotis G, Gray D, Kiafard Z, Zwirner J, Stockinger B. Functional specialization of memory Th cells revealed by expression of integrin CD49b. J Immunol 2006; 177: 968-975.
21. Oshima S, Nakamura T, Namiki S, Okada E, Tsuchiya K, Okamoto R et al. Interferon regulatory factor 1 (IRF-1) and IRF-2 distinctively up-regulate gene expression and production of interleukin-7 in human intestinal epithelial cells. Mol Cell Biol 2004; 24: 6298-6310.
22. Shalapour S, Deiser K, Sercan O, Tuckermann J, Minnich K, Willimsky G et al. Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo. Eur J Immunol 2010; 40: 2391-2400.
23. von Andrian UH, Mempel TR. Homing and cellular traffic in lymph nodes. Nat Rev Immunol 2003; 3: 867-878.
24. Holtkotter O, Nieswandt B, Smyth N, Muller W, Hafner M, Schulte V et al. Integrin alpha 2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen. J Biol Chem 2002; 277: 10789-10794.
25. Hara T, Shitara S, Imai K, Miyachi H, Kitano S, Yao H et al. Identification of IL-7- producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice. J Immunol 2012; 189: 1577-1584.
26. Frentsch M, Arbach O, Kirchhoff D, Moewes B, Worm M, Rothe M et al. Direct access to CD4+ T cells specific for defined antigens according to CD154 expression. Nat Med 2005; 11: 1118-1124.
27. Tokoyoda K, Egawa T, Sugiyama T, Choi BI, Nagasawa T. Cellular niches controlling B lymphocyte behavior within bone marrow during development. Immunity 2004; 20: 707-718.