pH-sensitive degradable nanoparticles for highly efficient intracellular delivery of exogenous protein

International Journal of Nanomedicine

Volumn 8, Issue , 2013, Pages 3405-3414

  Xu, Dan ^a   Wu, Fei ^a   Chen, Yinghui ^b   Wei, Liangming ^c   Yuan, Weien ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c Shanghai Jiao Tong University   (China)

Author keywords

Apoptosis; Cellular uptake; Nanoparticles; Protein delivery

Indexed keywords

APOPTIN; BOVINE SERUM ALBUMIN; DEXTRAN; ENHANCED GREEN FLUORESCENT PROTEIN; MACROGOL; NANOPARTICLE;

APOPTOSIS; ARTICLE; BIODEGRADABILITY; CELL ENCAPSULATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DRUG DELIVERY SYSTEM; ENDOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROPHILICITY; MOLECULAR WEIGHT; MORPHOLOGY; NANOMEDICINE; NICK END LABELING; PARTICLE SIZE; PH; PROTEIN SECRETION; SCANNING ELECTRON MICROSCOPY; THERMODYNAMICS; ZETA POTENTIAL;

APOPTOSIS; CELLULAR UPTAKE; NANOPARTICLES; PROTEIN DELIVERY;

DELAYED-ACTION PREPARATIONS; ENDOSOMES; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; NANOCAPSULES; PROTEINS;

EID: 84884276815     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S47701     Document Type: Article

References (36)

1. Kerbel R, Folkman J. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer. 2002;2:727-739.
2. Harries M, Smith I. The development and clinical use of trastuzumab (Herceptin). Endocr Relat Cancer. 2002;9:75-85.
3. Marshall H. Anti-CD20 antibody therapy is highly effective in the treatment of follicular lymphoma. Trends Immunol. 2001;22:183-184.
4. Schrama D, Reisfeld RA, Becker JC. Antibody targeted drugs as cancer therapeutics. Nat Rev Drug Discov. 2006;5:147-159.
5. Torchilin VP, Lukyanov AN. Peptide and protein drug delivery to and into tumors: challenges and solutions. Drug Discov Today. 2003;8: 259-266.
6. Liu G, Xu D, Jiang M, Yuan W. Preparation of bioactive interferon alpha-loaded polysaccharide nanoparticles using a new approach of temperature-induced water phase/water-phase emulsion. Int J Nanomed. 2012;7:4841-4848.
7. Kam NW, Dai H. Carbon nanotubes as intracellular protein transporters: generality and biological functionality. J Am Chem Soc. 2005;127: 6021-6026.
8. Lee Y, Ishii T, Cabral H, et al. Charge-conversional polyionic complex micelles-efficient nanocarriers for protein delivery into cytoplasm. Angew Chem Int Ed Engl. 2009;48:5309-5312.
9. Kim SK, Foote MB, Huang L. The targeted intracellular delivery of cytochrome C protein to tumors using lipid-apolipoprotein nanoparticles. Biomaterials. 2012;33:3959-3966.
10. Kim YH, Chun HY. Effects of the basic-state wind on secondary waves generated by the breaking of gravity waves in the mesosphere. APJAS. 2009;45:91-100.
11. Panyam J, Labhasetwar V. Biodegradable nanoparticles for drug and gene delivery to cells and tissue. Adv Drug Deliv Rev. 2003;55: 329-347.
12. Yuan W, Liu Z. Controlled-release and preserved bioactivity of proteins from (self-assembled) core-shell double-walled microspheres. Int J Nanomed. 2012;7:257-270.
13. Arifin DR, Palmer AF. Polymersome encapsulated hemoglobin: a novel type of oxygen carrier. Biomacromolecules. 2005;6:2172-2181.
14. Van Dijk-Wolthuis WN, Franssen O, Talsma H, Van Steenbergen MJ, Kettenes-van Den Bosch JJ, Hennink WE. Synthesis, characterization, and polymerization of glycidyl methacrylate derivatized dextran. Macromolecules. 1995;28:6317-6322.
15. Liu GJ, Ma SB, Li SK, et al. The highly efficient delivery of exogenous proteins into cells mediated by biodegradable chimaeric polymersomes. Biomaterials. 2010;31:7575-7585.
16. Yoo JW, Doshi N, Mitragotri S. Adaptive micro and nanoparticles: temporal control over carrier properties to facilitate drug delivery. Adv Drug Deliv Rev. 2011;63:1247-1256.
17. Zhang JC, Wu LL, Meng FH, et al. pH and reduction dual-bioresponsive polymersomes for efficient intracellular protein delivery. Langmuir. 2012;28:2056-2065.
18. Jiang J, Cole D, Westwood N, et al. Crucial roles for protein kinase C isoforms in tumor-specific killing by apoptin. Cancer Res. 2010;70: 7242-7252.
19. Yuan W, Geng Y, Wu F, et al. Preparation of polysaccharide glassy microparticles with stabilization of proteins. Int J Pharm. 2009;366: 154-159.
20. Kirby C, Gergoriadis G. Dehydration-rehydration vesicles: a simple method for high yield drug entrapment in liposomes. Bio/Technology. 1984;2:979-984.
21. Benavides J, Rito-Palomares M. Practical experiences from the development of aqueous two-phase processes for the recovery of high value biological products. J Chem Technol Biotechnol. 2008;83: 133-142.
22. Zaslavsky BY. Bioanalytical applications of partitioning in aqueous polymer two-phase systems. Anal Chem. 1992;64:765A-773A.
23. Jin T, Zhu J, Wu F, Yuan W, Geng LL, Zhu H. Preparing polymer-based sustained-release systems without exposing proteins to water-oil or water-air interfaces and cross-linking reagents. J Control Release. 2008;128:50-59.
24. Akagi T, Wang X, Uto T, Baba M, Akashi M. Protein direct delivery to dendritic cells using nanoparticles based on amphiphilic poly(amino acid) derivatives. Biomaterials. 2007;28:3427-3436.
25. Jin JL, Gong J, Yin TJ, et al. PTD4-apoptin protein and dacarbazine show a synergistic antitumor effect on B16-F1 melanoma in vitro and in vivo. Eur J Pharmacol. 2011;654:17-25.
26. Van Oorschot AAAM, Fischer DF, Grimbergen JM, et al. Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells. Proc Natl Acad Sci U S A. 1997;94:5843-5847.
27. Rohn JL, Zhang YH, Aalbers RI, et al. A tumor-specific kinase activity regulates the viral death protein apoptin. J Biol Chem. 2002;277: 50820-50827.
28. Guelen L, Paterson H, Gaken J, Meyers M, Farzaneh F, Tavassoli M. TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells. Oncogene. 2004;23:1153-1165.
29. Sun J, Yan Y, Wang X-T, et al. PTD4-apoptin protein therapy inhibits tumor growth in vivo. Int J Cancer. 2009;124:2973-2981.
30. Liu G, Hong X, Jiang M, Yuan W. Sustained-release GF micro-spheres using a novel solid-in-oil-in-oil-in-water emulsion method. Int J Nanomed. 2012;7:4559-4569.
31. Yuan W, Wu F, Guo M, Jin T. Development of protein delivery micro-sphere system by a novel S/O/O/W multi-emulsion. Eur J Pharm Sci. 2009;36(2/3):212-218.
32. Ren T, Yuan W, Zhao H, Jin T. Sustained-release polylactide-co-glycolide microspheres loaded with pre-formulated protein polysaccharide nano-particles. Micro Nano Lett. 2011;6:70-74.
33. Yuan W, Zhang Y, Wu F, et al. Preparation of protein-loaded sustained-release microspheres via 'solid-in-oil-in-hydrophilic oil-in-ethanol (S/O/hO/E)' emulsification. Colloids Surf B Biointerfaces. 2010;79:326-333.
34. Rong X, Mo X, Ren T, et al. Neuroprotective effect of erythropoietin-loaded composite microspheres on retinal ganglion cells in rats. Eur J Pharm Sci. 2011;43(4):334-342.
35. Yuan W, Hu Z, Su J, Wu F, Liu Z, Jin T. Preparation and characterizat{stroke}ion of recombinant human growth hormone-Zn 2+-dextran nanoparticles using aqueous phase-aqueous phase emulsion. Nanomedicine: Nanotechnology, Biology, and Medicine. 2012;8(4):424-427.
36. Noteborn MHM, De Boer GF, Van Roozelaar DJ, Karreman C, Kranenburg O, Vos JG, Jeurissen SHM, Hoeben RC, Zantema A, Koch G, Van Ormondt H, Van der Eb A J. Characterization of cloned chicken anemia virus DNA that contains all elements for the infections replication cycle. J Virol. 1991;65:3131-3139.