The targeted intracellular delivery of cytochrome C protein to tumors using lipid-apolipoprotein nanoparticles

Biomaterials

Volumn 33, Issue 15, 2012, Pages 3959-3966

  Kim, Sang Kyoon ^a   Foote, Michael B ^a   Huang, Leaf ^a  

^a University of North Carolina   (United States)

Author keywords

Anisamide; Apolipoprotein; Liposome; Nanoparticle; PEGylation; Protein delivery

Indexed keywords

ANISAMIDE; APOLIPOPROTEIN; APOLIPOPROTEINS; CANCER CELLS; CELL CYTOPLASM; CYTOCHROME C; INTRACELLULAR DELIVERY; LOADING EFFICIENCY; LOW PERMEABILITY; LUNG CANCER; LUNG TUMOR; MASSIVE APOPTOSIS; MEMBRANE-PERMEABLE; MODEL PROTEINS; NANOPARTICLE FORMULATION; PEGYLATION; PROTEIN DELIVERY; PROTEIN DRUGS; PROTEIN LOADINGS; TARGETED DELIVERY; THERAPEUTIC PROTEIN; TUMOR GROWTH; TUMOR SITE; TUMOR TARGETING;

BIOLOGICAL ORGANS; CELL DEATH; ENZYME ACTIVITY; ENZYME INHIBITION; LIPOSOMES; MAMMALS; NANOPARTICLES; TUMORS;

PROTEINS;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; APOLIPOPROTEIN A1; CASPASE 3; CYTOCHROME C; DOPE; GREEN FLUORESCENT PROTEIN; LIPID; MACROGOL DERIVATIVE; NANOCARRIER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CANCER INHIBITION; CANCER MODEL; CANCER SIZE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG PENETRATION; FEMALE; FLUORESCENCE ANALYSIS; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; MEMBRANE PERMEABILITY; MOUSE; NANOFABRICATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; TARGET CELL;

AMINO ACID SEQUENCE; ANIMALS; ANNEXIN A5; APOLIPOPROTEINS; APOPTOSIS; CASPASE 3; CELL LINE, TUMOR; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CYTOCHROMES C; DRUG DELIVERY SYSTEMS; ENZYME ACTIVATION; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENOUS; INTRACELLULAR SPACE; LIPIDS; MICE; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE; PROPIDIUM; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 84862812307     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.02.010     Document Type: Article

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