Sustained-release G-CSF microspheres using a novel solid-in-oil-in-oil-in-water emulsion method

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 4559-4569

  Liu, Guang ^a   Hong, Xiaoyun ^b   Jiang, Mier ^a   Yuan, Weien ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Bioactivity; G CSF; Microspheres; Stability; Sustained release

Indexed keywords

DEXTRAN; GRANULOCYTE COLONY STIMULATING FACTOR; MACROGOL; MICROSPHERE; NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DEGRADATION KINETICS; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG EFFICACY; EMULSION; GEL PERMEATION CHROMATOGRAPHY; HEMATOPOIETIC CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MALE; MICROEMULSION; MOUSE; NANOEMULSION; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PHASE SEPARATION; PROTEIN AGGREGATION; RAT; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE;

ANIMALS; CELL LINE, TUMOR; DELAYED-ACTION PREPARATIONS; DEXTRANS; DRUG STABILITY; EMULSIONS; GRANULOCYTE COLONY-STIMULATING FACTOR; KINETICS; MALE; MICE; MICROSPHERES; NANOPARTICLES; NEUTROPHILS; OILS; RATS; RATS, SPRAGUE-DAWLEY; WATER;

EID: 84870313456     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S33993     Document Type: Article

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