-
1
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal, S., Ghilardi, N., Xie, M., De Sauvage, F.J. & Gurney, A.L. (2003) Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278, 1910-1914.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.3
De Sauvage, F.J.4
Gurney, A.L.5
-
2
-
-
44349132270
-
Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
-
Artis, D. (2008) Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut. Nat. Rev. Immunol. 8, 411-420.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 411-420
-
-
Artis, D.1
-
3
-
-
53649100675
-
ATP drives lamina propria TH17 cell differentiation
-
Atarashi, K., Nishimura, J., Shima, T., Umesaki, Y., Yamamoto, M., Onoue, M., Yagita, H., Ishii, N., Evans, R., Honda, K. & Takeda, K. (2008) ATP drives lamina propria TH17 cell differentiation. Nature 455, 808-812.
-
(2008)
Nature
, vol.455
, pp. 808-812
-
-
Atarashi, K.1
Nishimura, J.2
Shima, T.3
Umesaki, Y.4
Yamamoto, M.5
Onoue, M.6
Yagita, H.7
Ishii, N.8
Evans, R.9
Honda, K.10
Takeda, K.11
-
4
-
-
64049091276
-
Signal regulatory protein alpha (SIRPα)/CD47 interaction and function
-
Barclay, A.N. (2009) Signal regulatory protein alpha (SIRPα)/CD47 interaction and function. Curr. Opin. Immunol. 21, 47-52.
-
(2009)
Curr. Opin. Immunol.
, vol.21
, pp. 47-52
-
-
Barclay, A.N.1
-
5
-
-
0029813545
-
+ TH1-like responses
-
+ TH1-like responses. J. Clin. Invest. 98, 1010-1020.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1010-1020
-
-
Berg, D.J.1
Davidson, N.2
Kühn, R.3
Müller, W.4
Menon, S.5
Holland, G.6
Thompson-Snipes, L.7
Leach, M.W.8
Rennick, D.9
-
6
-
-
0035280238
-
Integrin-associated protein (CD47) and its ligands
-
Brown, E.J. & Frazier, W.A. (2001) Integrin-associated protein (CD47) and its ligands. Trends Cell Biol. 11, 130-135.
-
(2001)
Trends Cell Biol.
, vol.11
, pp. 130-135
-
-
Brown, E.J.1
Frazier, W.A.2
-
7
-
-
44349167059
-
Dendritic cells in intestinal immune regulation
-
Coombes, J.L. & Powrie, F. (2008) Dendritic cells in intestinal immune regulation. Nat. Rev. Immunol. 8, 435-446.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 435-446
-
-
Coombes, J.L.1
Powrie, F.2
-
8
-
-
34547788180
-
- and retinoic acid-dependent mechanism
-
- and retinoic acid-dependent mechanism. J. Exp. Med. 204, 1757-1764.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
Siddiqui, K.R.R.2
Arancibia-Cárcamo, C.V.3
Hall, J.4
Sun, C.5
Belkaid, Y.6
Powrie, F.7
-
9
-
-
34548764423
-
Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses
-
Denning, T.L., Wang, Y., Patel, S.R., Williams, I.R. & Pulendran, B. (2007) Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses. Nat. Immunol. 8, 1086-1094.
-
(2007)
Nat. Immunol.
, vol.8
, pp. 1086-1094
-
-
Denning, T.L.1
Wang, Y.2
Patel, S.R.3
Williams, I.R.4
Pulendran, B.5
-
10
-
-
69549084637
-
- dendritic cells
-
- dendritic cells. J. Exp. Med. 206, 2013-2025.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2013-2025
-
-
Fortin, G.1
Raymond, M.2
Van, V.Q.3
Rubio, M.4
Gautier, P.5
Sarfati, M.6
Franchimont, D.7
-
11
-
-
77950353786
-
Homeostasis and inflammation in the intestine
-
Garrett, W.S., Gordon, J.I. & Glimcher, L.H. (2010) Homeostasis and inflammation in the intestine. Cell 140, 859-870.
-
(2010)
Cell
, vol.140
, pp. 859-870
-
-
Garrett, W.S.1
Gordon, J.I.2
Glimcher, L.H.3
-
12
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi, F., Smith, K.D., Ozinsky, A., Hawn, T.R., Yi, E.C., Goodlett, D.R., Eng, J.K., Akira, S., Underhill, D.M. & Aderem, A. (2001) The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410, 1099-1103.
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
Hawn, T.R.4
Yi, E.C.5
Goodlett, D.R.6
Eng, J.K.7
Akira, S.8
Underhill, D.M.9
Aderem, A.10
-
13
-
-
34247877512
-
Mucosal dendritic cells
-
Iwasaki, A. (2007) Mucosal dendritic cells. Annu. Rev. Immunol. 25, 381-418.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 381-418
-
-
Iwasaki, A.1
-
15
-
-
35748985290
-
LPS-induced down-regulation of signal regulatory protein α contributes to innate immune activation in macrophages
-
Kong, X., Yan, H., Chen, L., Dong, L., Yang, W., Liu, Q., Yu, L., Huang, D., Liu, S., Liu, H., Wu, M. & Wang, H. (2007) LPS-induced down-regulation of signal regulatory protein α contributes to innate immune activation in macrophages. J. Exp. Med. 204, 2719-2731.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2719-2731
-
-
Kong, X.1
Yan, H.2
Chen, L.3
Dong, L.4
Yang, W.5
Liu, Q.6
Yu, L.7
Huang, D.8
Liu, S.9
Liu, H.10
Wu, M.11
Wang, H.12
-
16
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kühn, R., Löhler, J., Rennick, D., Rajewsky, K. & Müller, W. (1993) Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75, 263-274.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kühn, R.1
Löhler, J.2
Rennick, D.3
Rajewsky, K.4
Müller, W.5
-
18
-
-
77950349016
-
Th17 and regulatory T cells in mediating and restraining inflammation
-
Littman, D.R. & Rudensky, A.Y. (2010) Th17 and regulatory T cells in mediating and restraining inflammation. Cell 140, 845-858.
-
(2010)
Cell
, vol.140
, pp. 845-858
-
-
Littman, D.R.1
Rudensky, A.Y.2
-
19
-
-
68649126866
-
Interleukin-17-producing γδ T cells selectively expand in response to pathogen products and environmental signals
-
Martin, B., Hirota, K., Cua, D.J., Stockinger, B. & Veldhoen, M. (2009) Interleukin-17-producing γδ T cells selectively expand in response to pathogen products and environmental signals. Immunity 31, 321-330.
-
(2009)
Immunity
, vol.31
, pp. 321-330
-
-
Martin, B.1
Hirota, K.2
Cua, D.J.3
Stockinger, B.4
Veldhoen, M.5
-
20
-
-
59249086198
-
Functions and molecular mechanisms of the CD47-SIRPα signalling pathway
-
Matozaki, T., Murata, Y., Okazawa, H. & Ohnishi, H. (2009a) Functions and molecular mechanisms of the CD47-SIRPα signalling pathway. Trends Cell Biol. 19, 72-80.
-
(2009)
Trends Cell Biol.
, vol.19
, pp. 72-80
-
-
Matozaki, T.1
Murata, Y.2
Okazawa, H.3
Ohnishi, H.4
-
21
-
-
70349602267
-
Protein tyrosine phosphatase SHP-2: a proto-oncogene product that promotes Ras activation
-
Matozaki, T., Murata, Y., Saito, Y., Okazawa, H. & Ohnishi, H. (2009b) Protein tyrosine phosphatase SHP-2: a proto-oncogene product that promotes Ras activation. Cancer Sci. 100, 1786-1793.
-
(2009)
Cancer Sci.
, vol.100
, pp. 1786-1793
-
-
Matozaki, T.1
Murata, Y.2
Saito, Y.3
Okazawa, H.4
Ohnishi, H.5
-
22
-
-
38849145752
-
Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages
-
Miyake, A., Murata, Y., Okazawa, H., Ikeda, H., Niwayama, Y., Ohnishi, H., Hirata, Y. & Matozaki, T. (2008) Negative regulation by SHPS-1 of Toll-like receptor-dependent proinflammatory cytokine production in macrophages. Genes Cells 13, 209-219.
-
(2008)
Genes Cells
, vol.13
, pp. 209-219
-
-
Miyake, A.1
Murata, Y.2
Okazawa, H.3
Ikeda, H.4
Niwayama, Y.5
Ohnishi, H.6
Hirata, Y.7
Matozaki, T.8
-
23
-
-
37549047983
-
Massive but selective cytokine dysregulation in the colon of IL-10-/- mice revealed by multiplex analysis
-
Montufar-Solis, D., Schaefer, J., Hicks, M.J. & Klein, J.R. (2008) Massive but selective cytokine dysregulation in the colon of IL-10-/- mice revealed by multiplex analysis. Int. Immunol. 20, 141-154.
-
(2008)
Int. Immunol.
, vol.20
, pp. 141-154
-
-
Montufar-Solis, D.1
Schaefer, J.2
Hicks, M.J.3
Klein, J.R.4
-
24
-
-
38649101258
-
Exacerbating role of γδ T cells in chronic colitis of T-cell receptor α mutant mice
-
Nanno, M., Kanari, Y., Naito, T., et al. (2008) Exacerbating role of γδ T cells in chronic colitis of T-cell receptor α mutant mice. Gastroenterology 134, 481-490.
-
(2008)
Gastroenterology
, vol.134
, pp. 481-490
-
-
Nanno, M.1
Kanari, Y.2
Naito, T.3
-
25
-
-
0038771965
-
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
-
Neel, B.G., Gu, H. & Pao, L. δ The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling. Trends Biochem. Sci. 28, 284-293.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 284-293
-
-
Neel, B.G.1
Gu, H.2
Pao, L.3
-
26
-
-
12244297799
-
3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance
-
3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307, 254-258.
-
(2005)
Science
, vol.307
, pp. 254-258
-
-
Niess, J.H.1
Brand, S.2
Gu, X.3
Landsman, L.4
Jung, S.5
McCormick, B.A.6
Vyas, J.M.7
Boes, M.8
Ploegh, H.L.9
Fox, J.G.10
Littman, D.R.11
Reinecker, H.C.12
-
27
-
-
40449091849
-
Commensal gut flora drives the expansion of proinflammatory CD4 T cells in the colonic lamina propria under normal and inflammatory conditions
-
Niess, J.H., Leithäuser, F., Adler, G. & Reimann, J. (2008) Commensal gut flora drives the expansion of proinflammatory CD4 T cells in the colonic lamina propria under normal and inflammatory conditions. J. Immunol. 180, 559-568.
-
(2008)
J. Immunol.
, vol.180
, pp. 559-568
-
-
Niess, J.H.1
Leithäuser, F.2
Adler, G.3
Reimann, J.4
-
28
-
-
13544266570
-
Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system
-
Okazawa, H., Motegi, S., Ohyama, N., Ohnishi, H., Tomizawa, T., Kaneko, Y., Oldenborg, P.A., Ishikawa, O. & Matozaki, T. (2005) Negative regulation of phagocytosis in macrophages by the CD47-SHPS-1 system. J. Immunol. 174, 2004-2011.
-
(2005)
J. Immunol.
, vol.174
, pp. 2004-2011
-
-
Okazawa, H.1
Motegi, S.2
Ohyama, N.3
Ohnishi, H.4
Tomizawa, T.5
Kaneko, Y.6
Oldenborg, P.A.7
Ishikawa, O.8
Matozaki, T.9
-
29
-
-
0034674421
-
Role of CD47 as a marker of self on red blood cells
-
Oldenborg, P.A., Zheleznyak, A., Fang, Y.F., Lagenaur, C.F., Gresham, H.D. & Lindberg, F.P. (2000) Role of CD47 as a marker of self on red blood cells. Science 288, 2051-2054.
-
(2000)
Science
, vol.288
, pp. 2051-2054
-
-
Oldenborg, P.A.1
Zheleznyak, A.2
Fang, Y.F.3
Lagenaur, C.F.4
Gresham, H.D.5
Lindberg, F.P.6
-
30
-
-
47149110368
-
Mucosal macrophages and the regulation of immune responses in the intestine
-
Platt, A.M. & Mowat, A.M. (2008) Mucosal macrophages and the regulation of immune responses in the intestine. Immunol. Lett. 119, 22-31.
-
(2008)
Immunol. Lett.
, vol.119
, pp. 22-31
-
-
Platt, A.M.1
Mowat, A.M.2
-
31
-
-
0035321325
-
Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria
-
Rescigno, M., Urbano, M., Valzasina, B., et al. (2001) Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria. Nat. Immunol. 2, 361-367.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 361-367
-
-
Rescigno, M.1
Urbano, M.2
Valzasina, B.3
-
32
-
-
0035353211
-
- hematopoietic cells
-
- hematopoietic cells. Blood 97, 2741-2749.
-
(2001)
Blood
, vol.97
, pp. 2741-2749
-
-
Seiffert, M.1
Brossart, P.2
Cant, C.3
Rappold, I.4
Brugger, W.5
Kanz, L.6
Brown, E.J.7
Ullrich, A.8
Bühring, H.J.9
-
33
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
Sellon, R.K., Tonkonogy, S., Schultz, M., Dieleman, L., Grenther, W., Balish, E., Rennick, D.M. & Sartor, R. (1998) Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect. Immun. 66, 5224-5231.
-
(1998)
Infect. Immun.
, vol.66
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
Dieleman, L.4
Grenther, W.5
Balish, E.6
Rennick, D.M.7
Sartor, R.8
-
34
-
-
8344242910
-
IL-12 p40 prevents the development of chronic enterocolitis in IL-10-deficient mice
-
Shiraki, M., Aihara, H., Kinouchi, Y., Takahashi, S., Oki, M., Noguchi, M., Takahashi, K., Miyazaki, J. & Shimosegawa, T. (2004) IL-12 p40 prevents the development of chronic enterocolitis in IL-10-deficient mice. Lab. Invest. 84, 1491-1500.
-
(2004)
Lab. Invest.
, vol.84
, pp. 1491-1500
-
-
Shiraki, M.1
Aihara, H.2
Kinouchi, Y.3
Takahashi, S.4
Oki, M.5
Noguchi, M.6
Takahashi, K.7
Miyazaki, J.8
Shimosegawa, T.9
-
35
-
-
4744351434
-
Development of intestinal inflammation in double IL-10- and leptin-deficient mice
-
Siegmund, B., Sennello, J.A., Lehr, H.A., Batra, A., Fedke, I., Zeitz, M. & Fantuzzi, G. (2004) Development of intestinal inflammation in double IL-10- and leptin-deficient mice. J. Leukoc. Biol. 76, 782-786.
-
(2004)
J. Leukoc. Biol.
, vol.76
, pp. 782-786
-
-
Siegmund, B.1
Sennello, J.A.2
Lehr, H.A.3
Batra, A.4
Fedke, I.5
Zeitz, M.6
Fantuzzi, G.7
-
36
-
-
68649088121
-
Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity
-
Sutton, C.E., Lalor, S.J., Sweeney, C.M., Brereton, C.F., Lavelle, E.C. & Mills, K.H.G. (2009) Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity. Immunity 31, 331-341.
-
(2009)
Immunity
, vol.31
, pp. 331-341
-
-
Sutton, C.E.1
Lalor, S.J.2
Sweeney, C.M.3
Brereton, C.F.4
Lavelle, E.C.5
Mills, K.H.G.6
-
37
-
-
34548176272
-
Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells
-
Tezuka, H., Abe, Y., Iwata, M., Takeuchi, H., Ishikawa, H., Matsushita, M., Shiohara, T., Akira, S. & Ohteki, T. (2007) Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells. Nature 448, 929-933.
-
(2007)
Nature
, vol.448
, pp. 929-933
-
-
Tezuka, H.1
Abe, Y.2
Iwata, M.3
Takeuchi, H.4
Ishikawa, H.5
Matsushita, M.6
Shiohara, T.7
Akira, S.8
Ohteki, T.9
-
38
-
-
34548708064
-
Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice
-
Tomizawa, T., Kaneko, Y., Kaneko, Y., Saito, Y., Ohnishi, H., Okajo, J., Okuzawa, C., Ishikawa-Sekigami, T., Murata, Y., Okazawa, H., Okamoto, K., Nojima, Y. & Matozaki, T. (2007) Resistance to experimental autoimmune encephalomyelitis and impaired T cell priming by dendritic cells in Src homology 2 domain-containing protein tyrosine phosphatase substrate-1 mutant mice. J. Immunol. 179, 869-877.
-
(2007)
J. Immunol.
, vol.179
, pp. 869-877
-
-
Tomizawa, T.1
Kaneko, Y.2
Kaneko, Y.3
Saito, Y.4
Ohnishi, H.5
Okajo, J.6
Okuzawa, C.7
Ishikawa-Sekigami, T.8
Murata, Y.9
Okazawa, H.10
Okamoto, K.11
Nojima, Y.12
Matozaki, T.13
-
39
-
-
45549099429
-
Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5
-
Uematsu, S., Fujimoto, K., Jang, M.H., Yang, B., Jung, Y., Nishiyama, M., Sato, S., Tsujimura, T., Yamamoto, M., Yokota, Y., Kiyono, H., Miyasaka, M., Ishii, K.J. & Akira, S. (2008) Regulation of humoral and cellular gut immunity by lamina propria dendritic cells expressing Toll-like receptor 5. Nat. Immunol. 9, 769-776.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 769-776
-
-
Uematsu, S.1
Fujimoto, K.2
Jang, M.H.3
Yang, B.4
Jung, Y.5
Nishiyama, M.6
Sato, S.7
Tsujimura, T.8
Yamamoto, M.9
Yokota, Y.10
Kiyono, H.11
Miyasaka, M.12
Ishii, K.J.13
Akira, S.14
-
40
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier, R.J. & Podolsky, D.K. (2007) Unravelling the pathogenesis of inflammatory bowel disease. Nature 448, 427-434.
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
41
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen, D., Cheung, J., Scheerens, H., Poulet, F., McClanahan, T., McKenzie, B., Kleinschek, M.A., Owyang, A., Mattson, J., Blumenschein, W., Murphy, E., Sathe, M., Cua, D.J., Kastelein, R.A. & Rennick, D. (2006) IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 116, 1310-1316.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
Kleinschek, M.A.7
Owyang, A.8
Mattson, J.9
Blumenschein, W.10
Murphy, E.11
Sathe, M.12
Cua, D.J.13
Kastelein, R.A.14
Rennick, D.15
-
42
-
-
0035176070
-
Modulation of the nuclear factor κB pathway by Shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor
-
You, M., Flick, L.M., Yu, D. & Feng, G.S. (2001) Modulation of the nuclear factor κB pathway by Shp-2 tyrosine phosphatase in mediating the induction of interleukin (IL)-6 by IL-1 or tumor necrosis factor. J. Exp. Med. 193, 101-110.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 101-110
-
-
You, M.1
Flick, L.M.2
Yu, D.3
Feng, G.S.4
|