Potential autophagy enhancers protect against fipronil-induced apoptosis in SH-SY5Y cells

Toxicology Letters

Volumn 223, Issue 1, 2013, Pages 25-34

  Park, Jae Hyeon ^a,b   Lee, Jeong Eun ^a,b   Lee, Soo Jin ^a   Park, Soo Jin ^c   Park, Kyung Hun ^c   Jeong, Mihye ^c   Koh, Hyun Chul ^a,b  

^a Hanyang University   (South Korea)

^b Hanyang Biomedical Research Institute   (South Korea)

^c National Institute of Animal Science   (South Korea)

Author keywords

Apoptosis; Autophagy; Fipronil; Neuroprotection; Rapamycin; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE 9; FIPRONIL; RAPAMYCIN; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DEATH; CHROMATIN CONDENSATION; CONTROLLED STUDY; FRAGMENTATION REACTION; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; NEUROTOXICITY; OXIDATIVE STRESS; PRIORITY JOURNAL;

APOPTOSIS; AUTOPHAGY; FIPRONIL; NEUROPROTECTION; RAPAMYCIN; REACTIVE OXYGEN SPECIES;

APOPTOSIS; AUTOPHAGY; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL SURVIVAL; DRUG INTERACTIONS; HUMANS; INSECTICIDES; L-LACTATE DEHYDROGENASE; OXIDATIVE STRESS; PYRAZOLES; SIROLIMUS;

EID: 84884265249     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2013.08.015     Document Type: Article

References (51)

1. Berridge M.V., Tan A.S. Characterization of the cellular reduction of 3-(4,5-dimethylthiazol2-yl)-2,5-diphenyltetrazolium bromide (MTT): Subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Archives of Biochemistry and Biophysics 1993, 303:474-482.
2. Boya P., Gonzalez-Polo R.A., Casares N., Perfettini J.L., Dessen P., Larochette N., Metivier D., Meley D., Souquere S., Yoshimori T., Pierron G., Codogno P., Kroemer G. Inhibition of macroautophagy triggers apoptosis. Molecular and Cellular Biology 2005, 25:1025-1040.
3. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 1976, 72:248-254.
4. Carloni S., Girelli S., Scopa C., Buonocore G., Longini M., Balduini W. Activation of auto-phagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamyc-in in neonatal hypoxia-ischemia. Autophagy 2010, 6:366-377.
5. Dadakhujaev S., Noh H.S., Jung E.J., Cha J.Y., Baek S.M., Ha J.H., Kim D.R. Autophagy protects the rotenone-induced cell death in alpha-synuclein overexpressing SH-SY5Y cells. Neuroscience Letters 2010, 472:47-52.
6. Das P.C., Cao Y., Cherrington N., Hodgson E., Rose R.L. Fipronil induces CYP isoforms and cytotoxicity in human hepatocytes. Chemico-Biological Interactions 2006, 164:200-214.
7. Dinis-Oliveira R.J., Remião F., Carmo H., Duarte J.A., Navarro A.S., Bastos M.L., Carvalho F. Paraquat exposure as an etiological factor of Parkinson's disease. Neurotoxicology 2006, 27:1110-1112.
8. Donati A., Cavallini G., Paradiso C., Vittorini S., Pollera M., Gori Z., Bergamini E. Age-related changes in the autophagic proteolysis of rat isolated liver cells: effects of antiaging dietary restrictions. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2001, 56:B375-B383.
9. Gonzalez-Polo R.A., Rodriguez-Martin A., Moran J.M., Niso M., Soler G., Fuentes J.M. Paraquat-induced apoptotic cell death in cerebellar granule cells. Brain Research 2004, 1011:170-176.
10. Gonzalez-Polo R.A., Niso-Santano M., Ortiz-Ortiz M.A., Gomez-Martin A., Moran J.M., Garcia-Rubio L., Francisco-Morcillo J., Zaragoza C., Soler G., Fuentes J.M. Inhibition of paraquat-induced autophagy accelerates the apoptotic cell death in neuroblastoma SH-SY5Y cells. Toxicological Sciences 2007, 97:448-458.
11. Gorell J.M., Johonson C.C., Rybicki B.A., Peterson E.L., Richardson R.J. The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living. Neurology 1998, 50:1346-1350.
12. Gupta R.C. Brain regional heterogeneity and toxicological mechanisms of organophosphates and carbamates. Toxicology Mechanisms and Methods 2004, 14:103-143.
13. Hamanaka R.B., Chandel N.S. Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes. Trends in Biochemical Sciences 2010, 35:505-513.
14. He C., Klionsky D.J. Regulation mechanisms and signaling pathways of autophagy. Annual Review of Genetics 2009, 43:67-93.
15. Holt S.V., Wyspianska B., Randall K.J., James D., Foster J.R., Wilkinson R.W. The development of an immunohistochemical method to detect the autophagy-associated protein LC3-II in human tumor xenografts. Toxicologic Pathology 2011, 39:516-523.
16. Hsuan S.L., Klintworth H.M., Xia Z. Basic fibroblast growth factor protects against rotenone-induced dopaminergic cell death through activation of extracellular signal-regulated kinases 1/2 and phosphatidylinositol-3 kinase pathways. Journal of Neuroscience 2006, 26:4481-4491.
17. Huang X., Moir R.D., Tanzi R.E., Bush A.I., Rogers J.T. Redox-active metals, oxidative stress, and Alzheimer's disease pathology. Annals of the New York Academy of Sciences 2004, 1012:153-163.
18. Julien L., Veronique G., Nicole P.H., Marion C. Fipronil-induced disruption of thyroid function in rats is mediated by increased total and free thyroxine clearances concomitantly to increased activity of hepatic enzymes. Toxicology 2009, 255:38-44.
19. Khan S., Salloum F., Das A., Xi L., Vetrovec G.W., Kukreja R.C. Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes. Journal of Molecular and Cellular Cardiology 2006, 41:256-264.
20. Ki Y.W., Lee J.E., Park J.H., Shin I.C., Koh H.C. Reactive oxygen species and mitogen-activated protein kinase induce apoptotic death of SH-SY5Y cells in response to fipronil. Toxicology Letters 2012, 211:18-28.
21. Kiffin R., et al. Oxidative stress and autophagy. Antioxidants & Redox Signaling 2006, 8:152-162.
22. Kim E.H., Sohn S., Kwon H.J., Kim S.U., Kim M.J., Lee S.J., Choi K.S. Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells. Cancer Research 2007, 67:6314-6324.
23. Komatsu M., Waguri S., Chiba T., Murata S., Iwata J., Tanida I., Ueno T., Koike M., Uchiyama Y., Kominami E., Tanaka K. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 2006, 441:880-884.
24. Kondo T., Takahashi S., Sato H., Yamada M., Kikuchi T., Furuya K. Cytotoxicity of size-density fractionated coal fly ash in rat alveolar macrophages cultured in vitro. Toxicology In Vitro 1993, 7:61-67.
25. LeBel C.P., Ischiropoulos H., Bondy S.C. Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress. Chemical Research Toxicology 1992, 5:227-231.
26. Lee J.E., Kang J.S., Ki Y.W., Lee S.H., Lee S.J., Lee K.S., Koh H.C. Akt/GSK3β signaling is involved in fipronil-induced apoptotic cell death of human neuroblastoma SH-SY5Y cells. Toxicology Letters 2011, 202:133-141.
27. Lee I.H., Kawai Y., Fergusson M.M., Rovira I.I., Bishop A.J., Motoyama N., Cao L., Finkel T. Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. Science 2012, 336:225-228.
28. Lee J.E., Park J.H., Shin I.C., Koh H.C. Reactive oxygen species regulated mitochondria-mediated apoptosis in PC12 cells exposed to chlorpyrifos. Toxicology and Applied Pharmacology 2012, 263:148-162.
29. Maiuri M.C., Zalckvar E., Kimchi A., Kroemer G. Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nature Reviews Molecular Cell Biology 2007, 8:741-752.
30. Malagelada C., Jin Z.H., Jackson-Lewis V., Przedborski S., Greene L.A. Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. The Journal of Neuroscience 2010, 30:1166-1175.
31. Meijer A.J., Codogno P. Autophagy: regulation and role in disease. Critical Reviews in Clinical Laboratory Sciences 2009, 46:210-240.
32. Mizushima N. Methods for monitoring autophagy. The International Journal of Biochemistry and Cell Biology 2004, 36:2491-2502.
33. Pan T., Kondo S., Zhu W., Xie W., Jankovic J., Le W. Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement. Neurobiology of Disease 2008, 32:16-25.
34. Park J.H., Lee J.E., Shin I.C., Koh H.C. Autophagy regulates chlorpyrifos-induced apoptosis in SH-SY5Y cells. Toxicology and Applied Pharmacology 2013, 268:55-67.
35. Ravikumar B., Berger Z., Vacher C., O'Kane C.J., Rubinsztein D.C. Rapamycin pretreatment protects against apoptosis. Human Molecular Genetics 2006, 15:1209-1216.
36. Sandhu L.C., Warters R.L., Dethlefsen L.A. Fluorescence studies of Hoechst 33342 with supercoiled and relaxed plasmid pBR322 DNA. Cytometry 1985, 6:191-194.
37. Saulsbury M.D., Heyliger S.O., Wang K., Johnson D.J. Chlopyrifos induces oxidative stress in oligodendrocyte progenitor cells. Toxicology 2009, 259:1-9.
38. Scherz-Shouval R., Elazar Z. Regulation of autophagy by ROS: physiology and pathology. Trends in Biochemical Sciences 2011, 36:30-38.
39. Scherz-Shouval R., Shvets E., Fass E., Shorer H., Gil L., Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO Journal 2007, 26:1749-1760.
40. Stehr C.M., Linbo T.L., Incardona J.P., Scholz N.L. The developmental neurotoxicity of fipronil; notochord degeneration and locomotor defects in zebrafish embryos and larvae. Toxicological Sciences 2006, 92:70-78.
41. Thorburn A. Apoptosis and autophagy: regulatory connections between two supposedly different processes. Apoptosis 2008, 13:1-9.
42. Tolkovsky A.M., Xue L., Fletcher G.C., Borutaite V. Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease?. Biochimie 2002, 84:233-240.
43. Underwood B.R., Imarisio S., Fleming A., Rose C., Krishna G., Heard P., Quick M., Korolchuk V.I., Renna M., Sarkar S., García-Arencibia M., O'Kane C.J., Murphy M.P., Rubinsztein D.C. Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease. Human Molecular Genetics 2010, 19:3413-3429.
44. Varro P., Gyo ri J., Vilagi I. In vitro effects of fipronil on neuronal excitability in mammalian and molluscan nervous systems. Annals of Agricultural and Environmental Medicine 2009, 16:71-77.
45. Vidau C., Brunet J.L., Badiou A., Belzunces L.P. Phenylpyrazole insecticides induce cytotoxicity by altering mechanisms involved in cellular energy supply in the human epithelial cell model Caco-2. Toxicoloy In Vitro 2009, 23:589-597.
46. Wang K., Klionsky D.J. Mitochondria removal by autophagy. Autophagy 2011, 7:297-300.
47. West R.J., Sweeney S.T. Oxidative stress and autophagy: mediators of synapse growth?. Autophagy 2012, 8:284-285.
48. Wu Y.T., Tan H.L., Shui G., Bauvy C., Huang Q., Wenk M.R., Ong C.N., Codogno P., Shen H.M. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. Journal of Biological Chemistry 2010, 285:10850-10861.
49. Yang C., Kaushal V., Shah S.V., Kaushal G.P. Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. American Journal of Physiology-Renal Physiology 2008, 294:F777-F787.
50. Yang J., Wu L.J., Tashino S., Onodera S., Ikejima T. Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells. Free Radical Research 2008, 42:492-504.
51. Yu F., Wang Z., Ju B., Wang Y., Wang J., Bai D. Apoptotic effect of organophosphorus insecticide chlorpyrifos on mouse retina in vivo via oxidative stress and protection of combination of vitamins C and E. Experimental and Toxicologic Pathology 2008, 59:415-423.