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Volumn 210, Issue 9, 2013, Pages 1793-1806

The microtubule-associated protein dcamkl1 regulates osteoblast function via repression of runx2

Author keywords

[No Author keywords available]

Indexed keywords

MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN DCAMKL1; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

EID: 84884252345     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20111790     Document Type: Article
Times cited : (51)

References (47)
  • 1
    • 32044468546 scopus 로고    scopus 로고
    • Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation
    • Bae, S.C., and Y.H. Lee. 2006. Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation. Gene. 366:58-66. http://dx.doi.org/10.1016/j.gene.2005.10.017
    • (2006) Gene , vol.366 , pp. 58-66
    • Bae, S.C.1    Lee, Y.H.2
  • 2
    • 0037673945 scopus 로고    scopus 로고
    • Osteoclast differentiation and activation
    • Boyle, W.J., W.S. Simonet, and D.L. Lacey. 2003. Osteoclast differentiation and activation. Nature. 423:337-342. http://dx.doi.org/10.1038/nature01658
    • (2003) Nature , vol.423 , pp. 337-342
    • Boyle, W.J.1    Simonet, W.S.2    Lacey, D.L.3
  • 3
    • 0034533439 scopus 로고    scopus 로고
    • Doublecortin-like kinase is associated with microtubules in neuronal growth cones
    • Burgess, H.A., and O. Reiner. 2000. Doublecortin-like kinase is associated with microtubules in neuronal growth cones. Mol. Cell. Neurosci. 16:529-541. http://dx.doi.org/10.1006/mcne.2000.0891
    • (2000) Mol. Cell. Neurosci. , vol.16 , pp. 529-541
    • Burgess, H.A.1    Reiner, O.2
  • 4
    • 0037124035 scopus 로고    scopus 로고
    • Alternative splice variants of doublecortinlike kinase are differentially expressed and have different kinase activities
    • Burgess, H.A., and O. Reiner. 2002. Alternative splice variants of doublecortinlike kinase are differentially expressed and have different kinase activities. J. Biol. Chem. 277:17696-17705. http://dx.doi.org/10.1074/jbc.M111981200
    • (2002) J. Biol. Chem. , vol.277 , pp. 17696-17705
    • Burgess, H.A.1    Reiner, O.2
  • 5
    • 0033571475 scopus 로고    scopus 로고
    • KIAA0369, doublecortin-like kinase, is expressed during brain development
    • Burgess, H.A., S. Martinez, and O. Reiner. 1999. KIAA0369, doublecortin-like kinase, is expressed during brain development. J. Neurosci. Res. 58:567-575. http://dx.doi.org/10.1002/(SICI)1097-4547(19991115)58:4567::AIDJNR93.0.CO;2-T
    • (1999) J. Neurosci. Res. , vol.58 , pp. 567-575
    • Burgess, H.A.1    Martinez, S.2    Reiner, O.3
  • 7
    • 47749125320 scopus 로고    scopus 로고
    • Stathmin-like 2, a developmentally- associated neuronal marker, is expressed and modulated during osteogenesis of human mesenchymal stem cells
    • Chiellini, C., G. Grenningloh, O. Cochet, M. Scheideler, Z. Trajanoski, G. Ailhaud, C. Dani, and E.Z. Amri. 2008. Stathmin-like 2, a developmentally- associated neuronal marker, is expressed and modulated during osteogenesis of human mesenchymal stem cells. Biochem. Biophys. Res. Commun. 374:64-68. http://dx.doi.org/10.1016/j.bbrc.2008.06.121
    • (2008) Biochem. Biophys. Res. Commun. , vol.374 , pp. 64-68
    • Chiellini, C.1    Grenningloh, G.2    Cochet, O.3    Scheideler, M.4    Trajanoski, Z.5    Ailhaud, G.6    Dani, C.7    Amri, E.Z.8
  • 9
    • 29544450409 scopus 로고    scopus 로고
    • Genetic interactions between doublecortin and doublecortin- like kinase in neuronal migration and axon outgrowth
    • Deuel, T.A., J.S. Liu, J.C. Corbo, S.Y. Yoo, L.B. Rorke-Adams, and C.A. Walsh. 2006. Genetic interactions between doublecortin and doublecortin- like kinase in neuronal migration and axon outgrowth. Neuron. 49:41-53. http://dx.doi.org/10.1016/j.neuron.2005.10.038
    • (2006) Neuron. , vol.49 , pp. 41-53
    • Deuel, T.A.1    Liu, J.S.2    Corbo, J.C.3    Yoo, S.Y.4    Rorke-Adams, L.B.5    Walsh, C.A.6
  • 10
    • 0030678549 scopus 로고    scopus 로고
    • Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation
    • Ducy, P., R. Zhang, V. Geoffroy, A.L. Ridall, and G. Karsenty. 1997. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell. 89:747-754. http://dx.doi.org/10.1016/S0092-8674(00)80257-3
    • (1997) Cell. , vol.89 , pp. 747-754
    • Ducy, P.1    Zhang, R.2    Geoffroy, V.3    Ridall, A.L.4    Karsenty, G.5
  • 11
    • 0000857494 scopus 로고
    • An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
    • Eng, J.K., A.L. McCormack, and J.R. Yates III. 1994. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J. Am. Soc. Mass Spectrom. 5:976-989. http://dx.doi.org/10.1016/1044-0305(94)80016-2
    • (1994) J. Am. Soc. Mass Spectrom. , vol.5 , pp. 976-989
    • Eng, J.K.1    McCormack, A.L.2    Yates, J.R.3
  • 12
    • 0028836022 scopus 로고
    • Toward a molecular understanding of skeletal development
    • Erlebacher, A., E.H. Filvaroff, S.E. Gitelman, and R. Derynck. 1995. Toward a molecular understanding of skeletal development. Cell. 80:371-378. http://dx.doi.org/10.1016/0092-8674(95)90487-5
    • (1995) Cell. , vol.80 , pp. 371-378
    • Erlebacher, A.1    Filvaroff, E.H.2    Gitelman, S.E.3    Derynck, R.4
  • 13
    • 70849127062 scopus 로고    scopus 로고
    • DCAMKL-1 expression identifies Tuft cells rather than stem cells in the adult mouse intestinal epithelium
    • Gerbe, F., B. Brulin, L. Makrini, C. Legraverend, and P. Jay. 2009. DCAMKL-1 expression identifies Tuft cells rather than stem cells in the adult mouse intestinal epithelium. Gastroenterology. 137:2179-2180. http://dx.doi.org/10.1053/j.gastro.2009.06.072
    • (2009) Gastroenterology. , vol.137 , pp. 2179-2180
    • Gerbe, F.1    Brulin, B.2    Makrini, L.3    Legraverend, C.4    Jay, P.5
  • 14
    • 0037673933 scopus 로고    scopus 로고
    • Control of osteoblast function and regulation of bone mass
    • Harada, S., and G.A. Rodan. 2003. Control of osteoblast function and regulation of bone mass. Nature. 423:349-355. http://dx.doi.org/10.1038/nature01660
    • (2003) Nature. , vol.423 , pp. 349-355
    • Harada, S.1    Rodan, G.A.2
  • 15
    • 0031020931 scopus 로고    scopus 로고
    • A new method for the modelindependent assessment of thickness in three-dimensional images
    • Hildebrand, T., and P. Rüegsegger. 1997. A new method for the modelindependent assessment of thickness in three-dimensional images. J. Microsc. 185:67-75. http://dx.doi.org/10.1046/j.1365-2818.1997 .1340694.x
    • (1997) J. Microsc. , vol.185 , pp. 67-75
    • Hildebrand, T.1    Rüegsegger, P.2
  • 17
    • 70349342805 scopus 로고    scopus 로고
    • Posttranslational regulation of Runx2 in bone and cartilage
    • Jonason, J.H., G. Xiao, M. Zhang, L. Xing, and D. Chen. 2009. Posttranslational regulation of Runx2 in bone and cartilage. J. Dent. Res. 88:693-703. http://dx.doi.org/10.1177/0022034509341629
    • (2009) J. Dent. Res. , vol.88 , pp. 693-703
    • Jonason, J.H.1    Xiao, G.2    Zhang, M.3    Xing, L.4    Chen, D.5
  • 18
    • 33744454653 scopus 로고    scopus 로고
    • Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3
    • Jones, D.C., M.N. Wein, M. Oukka, J.G. Hofstaetter, M.J. Glimcher, and L.H. Glimcher. 2006. Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3. Science. 312:1223-1227. http://dx.doi.org/10.1126/science.1126313
    • (2006) Science. , vol.312 , pp. 1223-1227
    • Jones, D.C.1    Wein, M.N.2    Hofstaetter, J.G.3    Oukka, M.4    Glimcher, M.J.5    Glimcher, L.H.6
  • 19
    • 0036225281 scopus 로고    scopus 로고
    • Reaching a genetic and molecular understanding of skeletal development
    • Karsenty, G., and E.F. Wagner. 2002. Reaching a genetic and molecular understanding of skeletal development. Dev. Cell. 2:389-406. http://dx.doi.org/10.1016/S1534-5807(02)00157-0
    • (2002) Dev. Cell. , vol.2 , pp. 389-406
    • Karsenty, G.1    Wagner, E.F.2
  • 21
    • 29544446945 scopus 로고    scopus 로고
    • Doublecortin-like kinase functions with doublecortin to mediate fiber tract decussation and neuronal migration
    • Koizumi, H., T. Tanaka, and J.G. Gleeson. 2006. Doublecortin-like kinase functions with doublecortin to mediate fiber tract decussation and neuronal migration. Neuron. 49:55-66. http://dx.doi.org/10.1016/j.neuron.2005.10.040
    • (2006) Neuron. , vol.49 , pp. 55-66
    • Koizumi, H.1    Tanaka, T.2    Gleeson, J.G.3
  • 22
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
    • Komori, T., H. Yagi, S. Nomura, A. Yamaguchi, K. Sasaki, K. Deguchi, Y. Shimizu, R.T. Bronson, Y.H. Gao, M. Inada, et al. 1997. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell. 89:755-764. http://dx.doi.org/10.1016/S0092-8674(00)80258-5
    • (1997) Cell. , vol.89 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3    Yamaguchi, A.4    Sasaki, K.5    Deguchi, K.6    Shimizu, Y.7    Bronson, R.T.8    Gao, Y.H.9    Inada, M.10
  • 24
    • 0034671293 scopus 로고    scopus 로고
    • DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization
    • Lin, P.T., J.G. Gleeson, J.C. Corbo, L. Flanagan, and C.A. Walsh. 2000. DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization. J. Neurosci. 20:9152-9161.
    • (2000) J. Neurosci. , vol.20 , pp. 9152-9161
    • Lin, P.T.1    Gleeson, J.G.2    Corbo, J.C.3    Flanagan, L.4    Walsh, C.A.5
  • 25
    • 58849164046 scopus 로고    scopus 로고
    • Molecular mechanisms in coupling of bone formation to resorption
    • Martin, T., J.H. Gooi, and N.A. Sims. 2009. Molecular mechanisms in coupling of bone formation to resorption. Crit. Rev. Eukaryot. Gene Expr. 19:73-88. http://dx.doi.org/10.1615/CritRevEukarGeneExpr.v19.i1.40
    • (2009) Crit. Rev. Eukaryot. Gene Expr. , vol.19 , pp. 73-88
    • Martin, T.1    Gooi, J.H.2    Sims, N.A.3
  • 26
    • 0033104802 scopus 로고    scopus 로고
    • Genomic structure, chromosomal mapping, and expression pattern of human DCAMKL1 (KIAA0369), a homologue of DCX (XLIS)
    • Matsumoto, N., D.T. Pilz, and D.H. Ledbetter. 1999. Genomic structure, chromosomal mapping, and expression pattern of human DCAMKL1 (KIAA0369), a homologue of DCX (XLIS). Genomics. 56:179-183. http://dx.doi.org/10.1006/geno.1998.5673
    • (1999) Genomics. , vol.56 , pp. 179-183
    • Matsumoto, N.1    Pilz, D.T.2    Ledbetter, D.H.3
  • 27
    • 43049128928 scopus 로고    scopus 로고
    • Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice
    • May, R., T.E. Riehl, C. Hunt, S.M. Sureban, S. Anant, and C.W. Houchen. 2008. Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice. Stem Cells. 26:630-637. http://dx.doi.org/10 .1634/stemcells.2007-0621
    • (2008) Stem Cells. , vol.26 , pp. 630-637
    • May, R.1    Riehl, T.E.2    Hunt, C.3    Sureban, S.M.4    Anant, S.5    Houchen, C.W.6
  • 28
    • 0019126423 scopus 로고
    • Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S
    • McLeod, M.J. 1980. Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S. Teratology. 22:299-301. http://dx.doi.org/10.1002/tera.1420220306
    • (1980) Teratology. , vol.22 , pp. 299-301
    • McLeod, M.J.1
  • 32
    • 0031613727 scopus 로고    scopus 로고
    • Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin
    • Omori, Y., M. Suzuki, K. Ozaki, Y. Harada, Y. Nakamura, E. Takahashi, and T. Fujiwara. 1998. Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin. J. Hum. Genet. 43:169-177. http://dx.doi.org/10.1007/s100380050063
    • (1998) J. Hum. Genet. , vol.43 , pp. 169-177
    • Omori, Y.1    Suzuki, M.2    Ozaki, K.3    Harada, Y.4    Nakamura, Y.5    Takahashi, E.6    Fujiwara, T.7
  • 33
    • 0030666372 scopus 로고    scopus 로고
    • Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
    • Otto, F., A.P. Thornell, T. Crompton, A. Denzel, K.C. Gilmour, I.R. Rosewell, G.W. Stamp, R.S. Beddington, S. Mundlos, B.R. Olsen, et al. 1997. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell. 89:765-771. http://dx.doi.org/10.1016/S0092-8674(00)80259-7
    • (1997) Cell. , vol.89 , pp. 765-771
    • Otto, F.1    Thornell, A.P.2    Crompton, T.3    Denzel, A.4    Gilmour, K.C.5    Rosewell, I.R.6    Stamp, G.W.7    Beddington, R.S.8    Mundlos, S.9    Olsen, B.R.10
  • 34
    • 0023488581 scopus 로고
    • Report of the ASBMR Histomorphometry Nomenclature Committee
    • Bone histomorphometry: standardization of nomenclature, symbols, and units
    • Parfitt, A.M., M.K. Drezner, F.H. Glorieux, J.A. Kanis, H. Malluche, P.J. Meunier, S.M. Ott, and R.R. Recker; Report of the ASBMR Histomorphometry Nomenclature Committee. 1987. Bone histomorphometry: standardization of nomenclature, symbols, and units. J. Bone Miner. Res. 2:595-610. http://dx.doi.org/10.1002/jbmr.5650020617
    • (1987) J. Bone Miner. Res. , vol.2 , pp. 595-610
    • Parfitt, A.M.1    Drezner, M.K.2    Glorieux, F.H.3    Kanis, J.A.4    Malluche, H.5    Meunier, P.J.6    Ott, S.M.7    Recker, R.R.8
  • 35
    • 33644966988 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation
    • Phillips, J.E., C.A. Gersbach, A.M. Wojtowicz, and A.J. García. 2006. Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation. J. Cell Sci. 119:581-591. http://dx.doi.org/10.1242/jcs.02758
    • (2006) J. Cell Sci. , vol.119 , pp. 581-591
    • Phillips, J.E.1    Gersbach, C.A.2    Wojtowicz, A.M.3    García, A.J.4
  • 38
    • 33646350024 scopus 로고    scopus 로고
    • Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation
    • Qiao, M., P. Shapiro, M. Fosbrink, H. Rus, R. Kumar, and A. Passaniti. 2006. Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation. J. Biol. Chem. 281:7118-7128. http://dx.doi.org/10.1074/jbc.M508162200
    • (2006) J. Biol. Chem. , vol.281 , pp. 7118-7128
    • Qiao, M.1    Shapiro, P.2    Fosbrink, M.3    Rus, H.4    Kumar, R.5    Passaniti, A.6
  • 39
    • 0345270439 scopus 로고    scopus 로고
    • Catalytic and regulatory domains of doublecortin kinase-1
    • Shang, L., Y.G. Kwon, S. Nandy, D.S. Lawrence, and A.M. Edelman. 2003. Catalytic and regulatory domains of doublecortin kinase-1. Biochemistry. 42:2185-2194. http://dx.doi.org/10.1021/bi026913i
    • (2003) Biochemistry. , vol.42 , pp. 2185-2194
    • Shang, L.1    Kwon, Y.G.2    Nandy, S.3    Lawrence, D.S.4    Edelman, A.M.5
  • 40
    • 29544438645 scopus 로고    scopus 로고
    • Doublecortin-like kinase controls neurogenesis by regulating mitotic spindles and M phase progression
    • Shu, T., H.C. Tseng, T. Sapir, P. Stern, Y. Zhou, K. Sanada, A. Fischer, F.M. Coquelle, O. Reiner, and L.H. Tsai. 2006. Doublecortin-like kinase controls neurogenesis by regulating mitotic spindles and M phase progression. Neuron. 49:25-39. http://dx.doi.org/10.1016/j.neuron.2005 .10.039
    • (2006) Neuron. , vol.49 , pp. 25-39
    • Shu, T.1    Tseng, H.C.2    Sapir, T.3    Stern, P.4    Zhou, Y.5    Sanada, K.6    Fischer, A.7    Coquelle, F.M.8    Reiner, O.9    Tsai, L.H.10
  • 41
    • 0033557797 scopus 로고    scopus 로고
    • DCAMKL1, a brain-specific transmembrane protein on 13q12.3 that is similar to doublecortin (DCX)
    • Sossey-Alaoui, K., and A.K. Srivastava. 1999. DCAMKL1, a brain-specific transmembrane protein on 13q12.3 that is similar to doublecortin (DCX). Genomics. 56:121-126. http://dx.doi.org/10.1006/geno.1998.5718
    • (1999) Genomics. , vol.56 , pp. 121-126
    • Sossey-Alaoui, K.1    Srivastava, A.K.2
  • 43
    • 84984933087 scopus 로고    scopus 로고
    • The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry
    • Villén, J., and S.P. Gygi. 2008. The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry. Nat. Protoc. 3:1630-1638. http://dx.doi.org/10.1038/nprot.2008.150
    • (2008) Nat. Protoc. , vol.3 , pp. 1630-1638
    • Villén, J.1    Gygi, S.P.2
  • 44
    • 0036774003 scopus 로고    scopus 로고
    • Serine phosphorylation of RUNX2 with novel potential functions as negative regulatory mechanisms
    • Wee, H.J., G. Huang, K. Shigesada, and Y. Ito. 2002. Serine phosphorylation of RUNX2 with novel potential functions as negative regulatory mechanisms. EMBO Rep. 3:967-974. http://dx.doi.org/10.1093/embo-reports/kvf193
    • (2002) EMBO Rep. , vol.3 , pp. 967-974
    • Wee, H.J.1    Huang, G.2    Shigesada, K.3    Ito, Y.4
  • 45
    • 34447132814 scopus 로고    scopus 로고
    • Skeletal remodeling in health and disease
    • Zaidi, M. 2007. Skeletal remodeling in health and disease. Nat. Med. 13:791-801. http://dx.doi.org/10.1038/nm1593
    • (2007) Nat. Med. , vol.13 , pp. 791-801
    • Zaidi, M.1
  • 47
    • 61749093281 scopus 로고    scopus 로고
    • Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2
    • Zhao, M., S.Y. Ko, J.H. Liu, D. Chen, J. Zhang, B. Wang, S.E. Harris, B.O. Oyajobi, and G.R. Mundy. 2009. Inhibition of microtubule assembly in osteoblasts stimulates bone morphogenetic protein 2 expression and bone formation through transcription factor Gli2. Mol. Cell. Biol. 29:1291-1305. http://dx.doi.org/10.1128/MCB.01566-08
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 1291-1305
    • Zhao, M.1    Ko, S.Y.2    Liu, J.H.3    Chen, D.4    Zhang, J.5    Wang, B.6    Harris, S.E.7    Oyajobi, B.O.8    Mundy, G.R.9


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