-
1
-
-
0020629599
-
Inhibition of microtubule assembly in vitro by TN-16, a synthetic antitumor drug
-
Arai, T. 1983. Inhibition of microtubule assembly in vitro by TN-16, a synthetic antitumor drug. FEBS Lett. 155:273-276.
-
(1983)
FEBS Lett
, vol.155
, pp. 273-276
-
-
Arai, T.1
-
3
-
-
16244411961
-
The ABCs of BMPs
-
Boden, S. D. 2005. The ABCs of BMPs. Orthop. Nurs. 24:49-52.
-
(2005)
Orthop. Nurs
, vol.24
, pp. 49-52
-
-
Boden, S.D.1
-
4
-
-
0037118285
-
High bone density due to a mutation in LDL-receptor-related protein 5
-
Boyden, L. M., J. Mao, J. Belsky, L. Mitzner, A. Farhi, M. A. Mitnick, D. Wu, K. Insogna, and R. P. Lifton. 2002. High bone density due to a mutation in LDL-receptor-related protein 5. N. Engl. J. Med. 346:1513-1521.
-
(2002)
N. Engl. J. Med
, vol.346
, pp. 1513-1521
-
-
Boyden, L.M.1
Mao, J.2
Belsky, J.3
Mitzner, L.4
Farhi, A.5
Mitnick, M.A.6
Wu, D.7
Insogna, K.8
Lifton, R.P.9
-
5
-
-
34147205885
-
Bmp2 transcription in osteoblast progenitors is regulated by a distant 3- enhancer located 156.3 kilobases from the promoter
-
Chandler, R. L., K. J. Chandler, K. A. McFarland, and D. P. Mortlock. 2007. Bmp2 transcription in osteoblast progenitors is regulated by a distant 3- enhancer located 156.3 kilobases from the promoter. Mol. Cell. Biol. 27: 2934-2951.
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 2934-2951
-
-
Chandler, R.L.1
Chandler, K.J.2
McFarland, K.A.3
Mortlock, D.P.4
-
6
-
-
0142153787
-
The Hedgehog signaling network
-
Cohen, M. M., Jr. 2003. The Hedgehog signaling network. Am. J. Med. Genet. 123:5-28.
-
(2003)
Am. J. Med. Genet
, vol.123
, pp. 5-28
-
-
Cohen Jr., M.M.1
-
7
-
-
0030678549
-
Osf2/Cbfa1: A transcriptional activator of osteoblast differentiation
-
Ducy, P., R. Zhang, V. Geoffroy, A. L. Ridall, and G. Karsenty. 1997. Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell 89:747-754.
-
(1997)
Cell
, vol.89
, pp. 747-754
-
-
Ducy, P.1
Zhang, R.2
Geoffroy, V.3
Ridall, A.L.4
Karsenty, G.5
-
8
-
-
0043237419
-
NF-κB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro
-
Feng, J. Q., L. P. Xing, J. H. Zhang, M. Zhao, D. Horn, J. Chan, B. F. Boyce, S. E. Harris, G. R. Mundy, and D. Chen. 2003. NF-κB specifically activates BMP-2 gene expression in growth plate chondrocytes in vivo and in a chondrocyte cell line in vitro. J. Biol. Chem. 278:29130-29135.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 29130-29135
-
-
Feng, J.Q.1
Xing, L.P.2
Zhang, J.H.3
Zhao, M.4
Horn, D.5
Chan, J.6
Boyce, B.F.7
Harris, S.E.8
Mundy, G.R.9
Chen, D.10
-
9
-
-
0031029768
-
Bone morph genetic protein2 transcripts in rapidly developing deer antler tissue contain an extended 5- non-coding region arising from a distal promoter
-
Feng, J. Q., D. Chen, N. Ghosh-Choudhury, J. Esparza, G. R. Mundy, and S. E. Harris. 1997. Bone morph genetic protein2 transcripts in rapidly developing deer antler tissue contain an extended 5- non-coding region arising from a distal promoter. Biochim. Biophys. Acta 1350:47-52.
-
(1997)
Biochim. Biophys. Acta
, vol.1350
, pp. 47-52
-
-
Feng, J.Q.1
Chen, D.2
Ghosh-Choudhury, N.3
Esparza, J.4
Mundy, G.R.5
Harris, S.E.6
-
10
-
-
0028242526
-
Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): Comparison of the structures and promoter regions of BMP-2 and BMP-4 genes
-
Feng, J. Q., M. A. Harris, N. Ghosh-Choudhury, M. Feng, G. R. Mundy, and S. E. Harris. 1994. Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes. Biochim. Biophys. Acta 1218:221-224.
-
(1994)
Biochim. Biophys. Acta
, vol.1218
, pp. 221-224
-
-
Feng, J.Q.1
Harris, M.A.2
Ghosh-Choudhury, N.3
Feng, M.4
Mundy, G.R.5
Harris, S.E.6
-
11
-
-
0029852463
-
The effects of aging on the bone inductive activity of recombinant human bone morphogenetic protein-2
-
Fleet, J. C., K. Cashman, K. Cox, and V. Rosen. 1996. The effects of aging on the bone inductive activity of recombinant human bone morphogenetic protein-2. Endocrinology 137:4605-4610.
-
(1996)
Endocrinology
, vol.137
, pp. 4605-4610
-
-
Fleet, J.C.1
Cashman, K.2
Cox, K.3
Rosen, V.4
-
12
-
-
0038819051
-
Selective inhibitors of the chymotrypsin-like activity of the osteoblast proteasome are potent stimulators of bone formation in vivo and in vitro
-
Garrett, I. R., D. Chen, G. Gutierrez, M. Zhao, A. Escobedo, G. Rossini, S. E. Harris, W. Gallwitz, K. B. Kim, S. Hu, C. M. Crews, and G. R. Mundy. 2003. Selective inhibitors of the chymotrypsin-like activity of the osteoblast proteasome are potent stimulators of bone formation in vivo and in vitro. J. Clin. Investig. 111:1771-1782.
-
(2003)
J. Clin. Investig
, vol.111
, pp. 1771-1782
-
-
Garrett, I.R.1
Chen, D.2
Gutierrez, G.3
Zhao, M.4
Escobedo, A.5
Rossini, G.6
Harris, S.E.7
Gallwitz, W.8
Kim, K.B.9
Hu, S.10
Crews, C.M.11
Mundy, G.R.12
-
13
-
-
0030041987
-
Immortalized murine osteoblasts derived from BMP-2T antigen expressing transgenic mice
-
Ghosh-Choudhury, N., J. J. Windle, B. A. Koop, M. A. Harris, D. L. Guerrero, J. M. Wozney, G. R. Mundy, and S. E. Harris. 1996. Immortalized murine osteoblasts derived from BMP-2T antigen expressing transgenic mice. Endocrinology 137:331-339.
-
(1996)
Endocrinology
, vol.137
, pp. 331-339
-
-
Ghosh-Choudhury, N.1
Windle, J.J.2
Koop, B.A.3
Harris, M.A.4
Guerrero, D.L.5
Wozney, J.M.6
Mundy, G.R.7
Harris, S.E.8
-
14
-
-
0034815601
-
Autoregulation of mouse BMP-2 gene transcription is directed by the proximal promoter element
-
Ghosh-Choudhury, N., G. Ghosh-Choudhury, M. A. Harris, J. M. Wozney, G. R. Mundy, S. L. Abboud, and S. E. Harris. 2001. Autoregulation of mouse BMP-2 gene transcription is directed by the proximal promoter element. Biochem. Biophys. Res. Commun. 286:101-108.
-
(2001)
Biochem. Biophys. Res. Commun
, vol.286
, pp. 101-108
-
-
Ghosh-Choudhury, N.1
Ghosh-Choudhury, G.2
Harris, M.A.3
Wozney, J.M.4
Mundy, G.R.5
Abboud, S.L.6
Harris, S.E.7
-
15
-
-
85130083791
-
-
Govender, S, C. Csimma, H. K. Genant, A. Valentin-Opran, Y. Amit, R. Arbel, H. Aro, D. Atar, M. Bishay, M. G. Borner, P. Chiron, P. Choong, J. Cinats, B. Courtenay, R. Feibel, B. Geulette, C. Gravel, N. Haas, M. Raschke, E. Hammacher, D. van der Velde, P. Hardy, M. Holt, C. Josten, R. L. Ketterl, B. Lindeque, G. Lob, H. Mathevon, G. McCoy, D. Marsh, R. Miller, E. Munting, S. Oeyre, L. Nordsletten, A. Patel, A. Pohl, W. Rennie, P. Revnders, P. M. Rommens, J. Rondia, W. C. Rossouw, P. J. Daneel, S. Ruff, A. Ruter, S. Santavirta, T. A. Schildhauer, C. Gekle, R. Schnettler, D. Segal, H. Seiler, R. B. Snowdowne, J. Stapert, G. Taglang, R. Verdonk, L. Vogels, A. Weckbach, A. Wentzensen, T. Wisniewski, and the BMP-2 Evaluation in Surgery for Tibial Trauma (BESTT) Study Group. 2002. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J. Bone Joint Surg. Am. 84:2123
-
Govender, S., C. Csimma, H. K. Genant, A. Valentin-Opran, Y. Amit, R. Arbel, H. Aro, D. Atar, M. Bishay, M. G. Borner, P. Chiron, P. Choong, J. Cinats, B. Courtenay, R. Feibel, B. Geulette, C. Gravel, N. Haas, M. Raschke, E. Hammacher, D. van der Velde, P. Hardy, M. Holt, C. Josten, R. L. Ketterl, B. Lindeque, G. Lob, H. Mathevon, G. McCoy, D. Marsh, R. Miller, E. Munting, S. Oeyre, L. Nordsletten, A. Patel, A. Pohl, W. Rennie, P. Revnders, P. M. Rommens, J. Rondia, W. C. Rossouw, P. J. Daneel, S. Ruff, A. Ruter, S. Santavirta, T. A. Schildhauer, C. Gekle, R. Schnettler, D. Segal, H. Seiler, R. B. Snowdowne, J. Stapert, G. Taglang, R. Verdonk, L. Vogels, A. Weckbach, A. Wentzensen, T. Wisniewski, and the BMP-2 Evaluation in Surgery for Tibial Trauma (BESTT) Study Group. 2002. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: a prospective, controlled, randomized study of four hundred and fifty patients. J. Bone Joint Surg. Am. 84:2123-2134.
-
-
-
-
17
-
-
33646568133
-
Microfabricated discontinuous-edge surface topographies influence osteoblast adhesion, migration, cytoskeletal organization, and proliferation and enhance matrix and mineral deposition in vitro
-
Hamilton, D. W., K. S. Wong, and D. M. Brunette. 2006. Microfabricated discontinuous-edge surface topographies influence osteoblast adhesion, migration, cytoskeletal organization, and proliferation and enhance matrix and mineral deposition in vitro. Calcif. Tissue Int. 78:314-325.
-
(2006)
Calcif. Tissue Int
, vol.78
, pp. 314-325
-
-
Hamilton, D.W.1
Wong, K.S.2
Brunette, D.M.3
-
18
-
-
33646741205
-
The pharmacokinetics and safety of ABT-751, a novel, orally bioavailable sulfonamide antimitotic agent: Results of a phase 1 study
-
Hande, K. R., A. Hagey, J. Berlin, Y. Cai, K. Meek, H. Kobayashi, A. C. Lockhart, D. Medina, J. Sosman, G. B. Gordon, and M. L. Rothenberg. 2006. The pharmacokinetics and safety of ABT-751, a novel, orally bioavailable sulfonamide antimitotic agent: results of a phase 1 study. Clin. Cancer Res. 12:2834-2840.
-
(2006)
Clin. Cancer Res
, vol.12
, pp. 2834-2840
-
-
Hande, K.R.1
Hagey, A.2
Berlin, J.3
Cai, Y.4
Meek, K.5
Kobayashi, H.6
Lockhart, A.C.7
Medina, D.8
Sosman, J.9
Gordon, G.B.10
Rothenberg, M.L.11
-
19
-
-
0028878438
-
Recombinant bone morphogenetic protein 2 accelerates bone cell differentiation and stimulates BMP-2 mRNA expression and BMP-2 promoter activity in primary fetal rat calvarial osteoblast cultures
-
Harris, S. E., J. Q. Feng, M. A. Harris, N. Ghosh-Choudhury, M. R. Dallas, J. M. Wozney, and G. R. Mundy. 1995. Recombinant bone morphogenetic protein 2 accelerates bone cell differentiation and stimulates BMP-2 mRNA expression and BMP-2 promoter activity in primary fetal rat calvarial osteoblast cultures. Mol. Cell. Diff. 3:138-155.
-
(1995)
Mol. Cell. Diff
, vol.3
, pp. 138-155
-
-
Harris, S.E.1
Feng, J.Q.2
Harris, M.A.3
Ghosh-Choudhury, N.4
Dallas, M.R.5
Wozney, J.M.6
Mundy, G.R.7
-
20
-
-
0028346631
-
Expression of bone morphogenetic protein messenger RNA in prolonged cultures of fetal rat calvarial cells
-
Harris, S. E., M. Sabatini, M. A. Harris, J. Q. Feng, J. M. Wozney, and G. R. Mundy. 1994. Expression of bone morphogenetic protein messenger RNA in prolonged cultures of fetal rat calvarial cells. J. Bone Miner. Res. 9:389-394.
-
(1994)
J. Bone Miner. Res
, vol.9
, pp. 389-394
-
-
Harris, S.E.1
Sabatini, M.2
Harris, M.A.3
Feng, J.Q.4
Wozney, J.M.5
Mundy, G.R.6
-
21
-
-
13444295117
-
Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6
-
Holmen, S. L., T. A. Giambernardi, C. R. Zylstra, B. D. Buckner-Berghuis, J. H. Resau, J. F. Hess, V. Glatt, M. L. Bouxsein, M. Ai, M. L. Warman, and B. O. Williams. 2004. Decreased BMD and limb deformities in mice carrying mutations in both Lrp5 and Lrp6. J. Bone Miner. Res. 19:2033-2040.
-
(2004)
J. Bone Miner. Res
, vol.19
, pp. 2033-2040
-
-
Holmen, S.L.1
Giambernardi, T.A.2
Zylstra, C.R.3
Buckner-Berghuis, B.D.4
Resau, J.H.5
Hess, J.F.6
Glatt, V.7
Bouxsein, M.L.8
Ai, M.9
Warman, M.L.10
Williams, B.O.11
-
22
-
-
0032126734
-
Transducing Hedgehog. The story so far
-
Ingham, P. W. 1998. Transducing Hedgehog. The story so far. EMBO J. 17:3505-3511.
-
(1998)
EMBO J
, vol.17
, pp. 3505-3511
-
-
Ingham, P.W.1
-
23
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
Jordan, M. A., and L. Wilson. 2004. Microtubules as a target for anticancer drugs. Nat. Rev. Cancer 4:253-265.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
-
24
-
-
16644383067
-
KIF27 is one of orthologs for Drosophila Costal-2
-
Katoh, Y., and M. Katoh. 2004. KIF27 is one of orthologs for Drosophila Costal-2. Int. J. Oncol. 25:1875-1880.
-
(2004)
Int. J. Oncol
, vol.25
, pp. 1875-1880
-
-
Katoh, Y.1
Katoh, M.2
-
25
-
-
27744445194
-
Comparative genomics on Sonic hedgehog orthologs
-
Katoh, Y., and M. Katoh. 2005. Comparative genomics on Sonic hedgehog orthologs. Oncol. Rep. 14:1087-1090.
-
(2005)
Oncol. Rep
, vol.14
, pp. 1087-1090
-
-
Katoh, Y.1
Katoh, M.2
-
26
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori, T., H. Yagi, S. Nomura, A. Yamaguchi, K. Sasaki, K. Deguchi, Y. Shimizu, R. T. Bronson, Y. H. Gao, M. Inada, M. Sato, R. Okamoto, Y. Kitamura, S. Yoshiki, and T. Kishimoto. 1997. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89:755-764.
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
Shimizu, Y.7
Bronson, R.T.8
Gao, Y.H.9
Inada, M.10
Sato, M.11
Okamoto, R.12
Kitamura, Y.13
Yoshiki, S.14
Kishimoto, T.15
-
27
-
-
33744935032
-
Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling
-
Lipinski, R. J., J. J. Gipp, J. Zhang, J. D. Doles, and W. Bushman. 2006. Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling. Exp. Cell. Res. 312:1925-1938.
-
(2006)
Exp. Cell. Res
, vol.312
, pp. 1925-1938
-
-
Lipinski, R.J.1
Gipp, J.J.2
Zhang, J.3
Doles, J.D.4
Bushman, W.5
-
28
-
-
0035318550
-
Tamoxifen and colchicine-modulated vinblastine followed by 5-fluorouracil in advanced renal cell carcinoma: A phase II study
-
Liu, J. H., M. H. Yang, F. S. Fan, C. C. Yen, W. S. Wang, Y. H. Chang, K. K. Chen, and P. M. Chen. 2001. Tamoxifen and colchicine-modulated vinblastine followed by 5-fluorouracil in advanced renal cell carcinoma: a phase II study. Urology 57:650-654.
-
(2001)
Urology
, vol.57
, pp. 650-654
-
-
Liu, J.H.1
Yang, M.H.2
Fan, F.S.3
Yen, C.C.4
Wang, W.S.5
Chang, Y.H.6
Chen, K.K.7
Chen, P.M.8
-
29
-
-
0035375351
-
Effect of aging on bone formation induced by recombinant human bone morphogenetic protein-2 combined with fibrous collagen membranes at subperiosteal sites
-
Matsumoto, A., K. Yamaji, M. Kawanami, and H. Kato. 2001. Effect of aging on bone formation induced by recombinant human bone morphogenetic protein-2 combined with fibrous collagen membranes at subperiosteal sites. J. Periodontal Res. 36:175-182.
-
(2001)
J. Periodontal Res
, vol.36
, pp. 175-182
-
-
Matsumoto, A.1
Yamaji, K.2
Kawanami, M.3
Kato, H.4
-
30
-
-
15444368753
-
The effect of cytoskeletal disruption on pulsatile fluid flow-induced nitric oxide and prostaglandin E2 release in osteocytes and osteoblasts
-
McGarry, J. G., J. Klein-Nulend, and P. J. Prendergast. 2005. The effect of cytoskeletal disruption on pulsatile fluid flow-induced nitric oxide and prostaglandin E2 release in osteocytes and osteoblasts. Biochem. Biophys. Res. Commun. 330:341-348.
-
(2005)
Biochem. Biophys. Res. Commun
, vol.330
, pp. 341-348
-
-
McGarry, J.G.1
Klein-Nulend, J.2
Prendergast, P.J.3
-
31
-
-
0038124322
-
Gene expression in older rats with delayed union of femoral fractures
-
Meyer, R. A., M. H. Meyer, M. Tenholder, W. R. Wondracel, and P. Garges. 2003. Gene expression in older rats with delayed union of femoral fractures. J. Bone Joint Surg. Am. 85:1243-1254.
-
(2003)
J. Bone Joint Surg. Am
, vol.85
, pp. 1243-1254
-
-
Meyer, R.A.1
Meyer, M.H.2
Tenholder, M.3
Wondracel, W.R.4
Garges, P.5
-
32
-
-
0030934042
-
Neurotoxicity of CI-980, a novel mitotic inhibitor
-
Meyers, C. A., A. P. Kudelka, C. A. Conrad, C. K. Gelke, W. Grove, and R. Pazdur. 1997. Neurotoxicity of CI-980, a novel mitotic inhibitor. Clin. Cancer Res. 3:419-422.
-
(1997)
Clin. Cancer Res
, vol.3
, pp. 419-422
-
-
Meyers, C.A.1
Kudelka, A.P.2
Conrad, C.A.3
Gelke, C.K.4
Grove, W.5
Pazdur, R.6
-
33
-
-
1242331822
-
Impaired endochondral bone development and osteopenia in Gli2-deficient mice
-
Miao, D., H. L. Liu, P. Plut, M. J. Niu, R. J. Huo, D. Goltzman, and J. E. Henderson. 2004. Impaired endochondral bone development and osteopenia in Gli2-deficient mice. Exp. Cell Res. 294:210-222.
-
(2004)
Exp. Cell Res
, vol.294
, pp. 210-222
-
-
Miao, D.1
Liu, H.L.2
Plut, P.3
Niu, M.J.4
Huo, R.J.5
Goltzman, D.6
Henderson, J.E.7
-
34
-
-
0031020221
-
Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development
-
Mo, R., A. M. Freer, D. L. Zinyk, M. A. Crackower, J. Michaud, H.H.-Q. Heng, K. W. Chik, X.-M. Shi, L.-C. Tsui, S. H. Cheng, A. L. Joyner, and C.-C. Hui. 1997. Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development. Development 124:113-123.
-
(1997)
Development
, vol.124
, pp. 113-123
-
-
Mo, R.1
Freer, A.M.2
Zinyk, D.L.3
Crackower, M.A.4
Michaud, J.5
Heng, H.H.-Q.6
Chik, K.W.7
Shi, X.-M.8
Tsui, L.-C.9
Cheng, S.H.10
Joyner, A.L.11
Hui, C.-C.12
-
35
-
-
0033521078
-
Stimulation of bone formation in vitro and in rodents by statins
-
Mundy, G. R., I. R. Garrett, S. E. Harris, J. Chan, D. Chen, G. Rossini, B. Boyce, M. Zhao, and G. Gutierrez. 1999. Stimulation of bone formation in vitro and in rodents by statins. Science 286:1946-1949.
-
(1999)
Science
, vol.286
, pp. 1946-1949
-
-
Mundy, G.R.1
Garrett, I.R.2
Harris, S.E.3
Chan, J.4
Chen, D.5
Rossini, G.6
Boyce, B.7
Zhao, M.8
Gutierrez, G.9
-
36
-
-
33644853818
-
Structural intermediates in microtubule assembly and disassembly: How and why?
-
Nogales, E., and H. W. Wang. 2006. Structural intermediates in microtubule assembly and disassembly: how and why? Curr. Opin. Cell Biol. 18:179-184.
-
(2006)
Curr. Opin. Cell Biol
, vol.18
, pp. 179-184
-
-
Nogales, E.1
Wang, H.W.2
-
37
-
-
33646494080
-
Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives
-
Nogales, E., and H. W. Wang. 2006. Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives. Curr. Opin. Struct. Biol. 16:221-229.
-
(2006)
Curr. Opin. Struct. Biol
, vol.16
, pp. 221-229
-
-
Nogales, E.1
Wang, H.W.2
-
38
-
-
0242625184
-
Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2
-
Ogden, S. K., M. Ascano, Jr., M. A. Stegman, L. M. Suber, J. E. Hooper, and D. J. Robbins. 2003. Identification of a functional interaction between the transmembrane protein Smoothened and the kinesin-related protein Costal2. Curr. Biol. 13:1998-2003.
-
(2003)
Curr. Biol
, vol.13
, pp. 1998-2003
-
-
Ogden, S.K.1
Ascano Jr., M.2
Stegman, M.A.3
Suber, L.M.4
Hooper, J.E.5
Robbins, D.J.6
-
39
-
-
0030666372
-
Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development
-
Otto, F., A. P. Thornell, T. Crompton, A. Denzel, K. C. Gilmour, I. R. Rosewell, G. W. Stamp, R. S. Beddington, S. Mundlos, B. R. Olsen, P. B. Selby, and M. J. Owen. 1997. Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89:765-771.
-
(1997)
Cell
, vol.89
, pp. 765-771
-
-
Otto, F.1
Thornell, A.P.2
Crompton, T.3
Denzel, A.4
Gilmour, K.C.5
Rosewell, I.R.6
Stamp, G.W.7
Beddington, R.S.8
Mundlos, S.9
Olsen, B.R.10
Selby, P.B.11
Owen, M.J.12
-
40
-
-
34249717798
-
A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome
-
Pan, Y., and B. Wang. 2007. A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome. J. Biol. Chem. 282:10846-10852.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 10846-10852
-
-
Pan, Y.1
Wang, B.2
-
41
-
-
33646270662
-
Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation
-
Pan, Y., C. B. Bai, A. L. Joyner, and B. Wang. 2006. Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation. Mol. Cell. Biol. 26:3365-3377.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 3365-3377
-
-
Pan, Y.1
Bai, C.B.2
Joyner, A.L.3
Wang, B.4
-
42
-
-
33845245610
-
GLI2 mutations in four Brazilian patients: How wide is the phenotypic spectrum?
-
Rahimov, F., L. A. Ribeiro, E. de Miranda, A. Richieri-Costa, and J. C. Murray. 2006. GLI2 mutations in four Brazilian patients: how wide is the phenotypic spectrum? Am. J. Med. Genet. A 140:2571-2576.
-
(2006)
Am. J. Med. Genet. A
, vol.140
, pp. 2571-2576
-
-
Rahimov, F.1
Ribeiro, L.A.2
de Miranda, E.3
Richieri-Costa, A.4
Murray, J.C.5
-
43
-
-
0030838880
-
Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2
-
Robbins, D. J., K. E. Nybakken, R. Kobayashi, J. C. Sisson, J. M. Bishop, and P. P. Therond. 1997. Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2. Cell 90:225-234.
-
(1997)
Cell
, vol.90
, pp. 225-234
-
-
Robbins, D.J.1
Nybakken, K.E.2
Kobayashi, R.3
Sisson, J.C.4
Bishop, J.M.5
Therond, P.P.6
-
44
-
-
0030891148
-
A binding site for Gli proteins is essential for HNF-3b floor plate enhancer activity in transgenics and can respond to Shh in vitro
-
Sasaki, H., C. C. Hui, M. Nakafuku, and H. Kondoh. 1997. A binding site for Gli proteins is essential for HNF-3b floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development 124:1313-1322.
-
(1997)
Development
, vol.124
, pp. 1313-1322
-
-
Sasaki, H.1
Hui, C.C.2
Nakafuku, M.3
Kondoh, H.4
-
45
-
-
0032848136
-
Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signaling
-
Sasaki, H., Y. Nishizaki, C. C. Hui, M. Nakafuku, and H. Kondoh. 1999. Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development 126:3915-3924.
-
(1999)
Development
, vol.126
, pp. 3915-3924
-
-
Sasaki, H.1
Nishizaki, Y.2
Hui, C.C.3
Nakafuku, M.4
Kondoh, H.5
-
46
-
-
34347400475
-
Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function
-
Shimoyama, A., M. Wada, F. Ikeda, K. Hata, T. Matsubara, A. Nifuji, M. Noda, K. Amano, A. Yamaguchi, R. Nishimura, and T. Yoneda. 2007. Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function. Mol. Cell. Biol. 18:2411-2418.
-
(2007)
Mol. Cell. Biol
, vol.18
, pp. 2411-2418
-
-
Shimoyama, A.1
Wada, M.2
Ikeda, F.3
Hata, K.4
Matsubara, T.5
Nifuji, A.6
Noda, M.7
Amano, K.8
Yamaguchi, A.9
Nishimura, R.10
Yoneda, T.11
-
47
-
-
34247577554
-
Accelerating lumbar fusions by combining rhBMP-2 with allograft bone: A prospective analysis of interbody fusion rates and clinical outcomes
-
Slosar, P. J., R. Josey, and J. Reynolds. 2006. Accelerating lumbar fusions by combining rhBMP-2 with allograft bone: a prospective analysis of interbody fusion rates and clinical outcomes. Spine J. 7:301-307.
-
(2006)
Spine J
, vol.7
, pp. 301-307
-
-
Slosar, P.J.1
Josey, R.2
Reynolds, J.3
-
48
-
-
0034698137
-
Identification of a tetrameric hedgehog signaling complex
-
Stegman, M. A., J. E. Vallance, G. Elangovan, J. Sosinski, Y. Cheng, and D. J. Robbins. 2000. Identification of a tetrameric hedgehog signaling complex. J. Biol. Chem. 275:21809-21812.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 21809-21812
-
-
Stegman, M.A.1
Vallance, J.E.2
Elangovan, G.3
Sosinski, J.4
Cheng, Y.5
Robbins, D.J.6
-
49
-
-
4243129131
-
-
Styrkarsdottir, U., J. B. Cazier, A. Kong, O. Rolfsson, H. Larsen, E. Bjarnadottir, V. D. Johannsdottir, M. S. Sigurdardottir, Y. Bagger, C. Christiansen, I. Reynisdottir, S. F. A. Grant, K. Jonasson, M. L. Frigge, J. R. Gulcher, G. Sigurdsson, and K. Stefansson. 2003. Linkage of osteoporosis to chromosome 20p12 and association to BMP-2. Public Libr. Sci. Biol. 1:1-10.
-
Styrkarsdottir, U., J. B. Cazier, A. Kong, O. Rolfsson, H. Larsen, E. Bjarnadottir, V. D. Johannsdottir, M. S. Sigurdardottir, Y. Bagger, C. Christiansen, I. Reynisdottir, S. F. A. Grant, K. Jonasson, M. L. Frigge, J. R. Gulcher, G. Sigurdsson, and K. Stefansson. 2003. Linkage of osteoporosis to chromosome 20p12 and association to BMP-2. Public Libr. Sci. Biol. 1:1-10.
-
-
-
-
50
-
-
0033565488
-
Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral disc
-
Takae, R., S. Matsunaga, N. Origuchi, T. Yamamoto, N. Morimoto, S. Suzuki, and T. Sakou. 1999. Immunolocalization of bone morphogenetic protein and its receptors in degeneration of intervertebral disc. Spine 24: 1397-1401.
-
(1999)
Spine
, vol.24
, pp. 1397-1401
-
-
Takae, R.1
Matsunaga, S.2
Origuchi, N.3
Yamamoto, T.4
Morimoto, N.5
Suzuki, S.6
Sakou, T.7
-
51
-
-
33751506452
-
BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing
-
Tsuji, K., A. Bandyopadhyay, B. D. Harf, K. Cox, S. Kakar, L. Gerstenfeld, T. Einhorn, C. J. Tabin, and V. Rosen. 2006. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing. Nat. Genet. 38:1424-1429.
-
(2006)
Nat. Genet
, vol.38
, pp. 1424-1429
-
-
Tsuji, K.1
Bandyopadhyay, A.2
Harf, B.D.3
Cox, K.4
Kakar, S.5
Gerstenfeld, L.6
Einhorn, T.7
Tabin, C.J.8
Rosen, V.9
-
52
-
-
34250019537
-
Bone formation by autoinduction
-
Urist, M. R. 1965. Bone formation by autoinduction. Science 150:893-899.
-
(1965)
Science
, vol.150
, pp. 893-899
-
-
Urist, M.R.1
-
53
-
-
0041919389
-
Hedgehog signalling: Off the shelf modulation
-
van den Heuvel, M. 2003. Hedgehog signalling: off the shelf modulation. Curr. Biol. 13:R686-R688.
-
(2003)
Curr. Biol
, vol.13
-
-
van den Heuvel, M.1
-
54
-
-
4744363325
-
SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome
-
Vuong, B. Q., T. L. Arenzana, B. M. Showalter, J. Losman, X. P. Chen, J. Mostecki, A. S. Banks, A. Limnander, N. Fernandez, and P. B. Rothman. 2004. SOCS-1 localizes to the microtubule organizing complex-associated 20S proteasome. Mol. Cell. Biol. 24:9092-9101.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 9092-9101
-
-
Vuong, B.Q.1
Arenzana, T.L.2
Showalter, B.M.3
Losman, J.4
Chen, X.P.5
Mostecki, J.6
Banks, A.S.7
Limnander, A.8
Fernandez, N.9
Rothman, P.B.10
-
55
-
-
0034681266
-
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
-
Wang, B., J. F. Fallon, and P. A. Beachy. 2000. Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100:423-434.
-
(2000)
Cell
, vol.100
, pp. 423-434
-
-
Wang, B.1
Fallon, J.F.2
Beachy, P.A.3
-
56
-
-
0024256133
-
Novel regulators of bone formation: Molecular clones and activities
-
Wozney, J. M., V. Rosen, A. J. Celeste, L. M. Mitsock, M. J. Whitters, R. Kriz, R. Hewick, and E. A. Wang. 1988. Novel regulators of bone formation: molecular clones and activities. Science 242:1528-1534.
-
(1988)
Science
, vol.242
, pp. 1528-1534
-
-
Wozney, J.M.1
Rosen, V.2
Celeste, A.J.3
Mitsock, L.M.4
Whitters, M.J.5
Kriz, R.6
Hewick, R.7
Wang, E.A.8
-
57
-
-
62849109875
-
Role of BMP-2 in postnatal bone biology: Conditional knockout (cKO) of BMP-2 using 3.6 collagen type 1a1-Cre model
-
Yang, W. C., D. Guo, J. Gluhak, M. A. Harris, A. Lichtler, B. Kream, J. Edwards, G. R. Mundy, Y. Mishina, and S. E. Harris. 2007. Role of BMP-2 in postnatal bone biology: conditional knockout (cKO) of BMP-2 using 3.6 collagen type 1a1-Cre model. J. Bone Miner. Res. 22(suppl. 1):S31.
-
(2007)
J. Bone Miner. Res
, vol.22
, Issue.SUPPL. 1
-
-
Yang, W.C.1
Guo, D.2
Gluhak, J.3
Harris, M.A.4
Lichtler, A.5
Kream, B.6
Edwards, J.7
Mundy, G.R.8
Mishina, Y.9
Harris, S.E.10
-
58
-
-
0031837128
-
Immunohistochemical localization of bone morphogenetic proteins and the receptors in epiphyseal growth plate
-
Yazaki, Y., S. Matsunaga, T. Onishi, T. Nagamine, N. Origuchi, T. Yamamoto, Y. Ishidou, T. Imamura, and T. Sakou. 1998. Immunohistochemical localization of bone morphogenetic proteins and the receptors in epiphyseal growth plate. Anticancer Res. 18:2339-2344.
-
(1998)
Anticancer Res
, vol.18
, pp. 2339-2344
-
-
Yazaki, Y.1
Matsunaga, S.2
Onishi, T.3
Nagamine, T.4
Origuchi, N.5
Yamamoto, T.6
Ishidou, Y.7
Imamura, T.8
Sakou, T.9
-
59
-
-
0007708272
-
Expression of recombinant mature peptide of human bone morphogenetic protein-2 in Escherichia coli and its activity of bone formation
-
Zhao, M., H. X. Wang, and T. C. Zhou. 1994. Expression of recombinant mature peptide of human bone morphogenetic protein-2 in Escherichia coli and its activity of bone formation. Chin. Biochem. J. 10:319-324.
-
(1994)
Chin. Biochem. J
, vol.10
, pp. 319-324
-
-
Zhao, M.1
Wang, H.X.2
Zhou, T.C.3
-
60
-
-
0041845297
-
E3 ubiquitin ligase Smurf1 mediates Cbfa1 degradation and plays a specific role in osteoblast differentiation
-
Zhao, M., M. Qiao, B. O. Oyajobi, G. R. Mundy, and D. Chen. 2003. E3 ubiquitin ligase Smurf1 mediates Cbfa1 degradation and plays a specific role in osteoblast differentiation. J. Biol. Chem. 278:27939-27944.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 27939-27944
-
-
Zhao, M.1
Qiao, M.2
Oyajobi, B.O.3
Mundy, G.R.4
Chen, D.5
-
61
-
-
33746987081
-
The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling
-
Zhao, M., M. Qiao, S. E. Harris, D. Chen, B. O. Oyajobi, and G. R. Mundy. 2006. The zinc finger transcription factor Gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling. Mol. Cell. Biol. 26:6197-6208.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 6197-6208
-
-
Zhao, M.1
Qiao, M.2
Harris, S.E.3
Chen, D.4
Oyajobi, B.O.5
Mundy, G.R.6
|