Ginkgolide B Reduces LOX-1 Expression by Inhibiting Akt Phosphorylation and Increasing Sirt1 Expression in Oxidized LDL-Stimulated Human Umbilical Vein Endothelial Cells

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Ma, Lina ^a,b   Liu, Xueqing ^a   Zhao, Yanyang ^a   Chen, Beidong ^a   Li, Xingguang ^b   Qi, Ruomei ^a  

^a BEIJING HOSPITAL   (China)

^b BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GINKGOLIDE B; INTERCELLULAR ADHESION MOLECULE 1; OXIDIZED LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PROTEIN KINASE B; SIRTUIN 1; TRANSCRIPTION FACTOR NRF2;

ARTICLE; CELL DAMAGE; CELL PROTECTION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; UMBILICAL VEIN ENDOTHELIAL CELL;

GENE EXPRESSION REGULATION; GINKGOLIDES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LACTONES; LIPOPROTEINS, LDL; NF-E2-RELATED FACTOR 2; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; SCAVENGER RECEPTORS, CLASS E; SIRTUIN 1;

EID: 84884245811     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0074769     Document Type: Article

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