Systemic coadministration of chloramphenicol with intravenous but not intracerebroventricular morphine markedly increases morphine antinociception and delays development of antinociceptive tolerance in rats

Drug Metabolism and Disposition

Volumn 28, Issue 2, 2000, Pages 236-244

  Smith, Maree T ^a   Nielsen, Carsten K ^a   Lim Fraser, Megan Y C ^a   Wright, Andrew W E ^a   Lau, Michael ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL HEMISUCCINATE; MORPHINE 3 GLUCURONIDE; MORPHINE SULFATE; OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANTINOCICEPTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG ELIMINATION; DRUG MECHANISM; DRUG POTENTIATION; MALE; METABOLIC INHIBITION; MORPHINE TOLERANCE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANALGESICS, OPIOID; ANIMALS; AREA UNDER CURVE; CHLORAMPHENICOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; DRUG TOLERANCE; FEMORAL ARTERY; GLUCURONIDES; INDICATORS AND REAGENTS; INFUSIONS, PARENTERAL; INJECTIONS, INTRAVENOUS; INJECTIONS, INTRAVENTRICULAR; JUGULAR VEINS; MALE; MORPHINE; MORPHINE DERIVATIVES; PAIN MEASUREMENT; PROTEIN SYNTHESIS INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0033969812     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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