Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat

Journal of Pharmacology and Experimental Therapeutics

Volumn 278, Issue 1, 1996, Pages 107-113

  Bickel, Ulrich ^a   Schumacher, Oliver P ^a   Kang, Young Sook ^b   Voigt, Karlheinz ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b Sookmyung Women's University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; TRITIUM;

ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; CONTROLLED STUDY; DIFFUSION; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG GLUCURONIDATION; DRUG HALF LIFE; DRUG PENETRATION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG UPTAKE; GUINEA PIG; INTRAVENOUS DRUG ADMINISTRATION; LIPOPHILICITY; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD-BRAIN BARRIER; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCURONATES; GUINEA PIGS; MALE; MORPHINE; PERMEABILITY; RATS; RATS, SPRAGUE-DAWLEY; SUCROSE; TIME FACTORS;

EID: 0030425327     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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