Mixed protein-DNA gel particles for DNA delivery: Role of protein composition and preparation method on biocompatibility

International Journal of Pharmaceutics

Volumn 454, Issue 1, 2013, Pages 192-203

  Moran M C ^a,b   Nogueira, D R ^a   Vinardell, M P ^a,b   Miguel, M G ^c   Lindman, B ^c,d  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Unidad Asociada de Geociencias Marinas   (Spain)

^c UNIVERSITY OF COIMBRA   (Portugal)

^d LUND UNIVERSITY   (Sweden)

Author keywords

DNA gels; Haemolysis; In vitro cytotoxicity; Particles; Size

Indexed keywords

ANIMAL CELL; ANTIGEN ANTIBODY REACTION; ARTICLE; BIOCOMPATIBILITY; CELL INTERACTION; CELL LINE; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ERYTHROCYTE; GEL; GENE TARGETING; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; ISOELECTRIC POINT; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA INTERACTION; PROTEIN SECONDARY STRUCTURE; TUMOR CELL LINE;

EID: 84884158218     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.06.041     Document Type: Article

References (39)

1. Abbasi, S., Paul, A., Prakash, S., 2011. Cationic albumin nanoparticles for enhanced drug delivery to treat breast cancer: preparation and in vitro assessment. Cell Biochem. Biophys. 61, 277-287.
2. Boverhof, D.R., David, R.M., 2010. Nanomaterial characterization: considerations and needs for hazard assessment and safety evaluation. Anal. Bioanal. Chem. 396, 953-961.
3. Bradford, M.M., 1986. A rapid and sensitive method for the quantification of micrograms quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
4. Costa, D., Morán, M.C., Miguel, M.G., Lindman, B., 2008. Cross-linked DNA gels and gel particles. In: Dias, R.S., Lindman, B. (Eds.), DNA Interactions with Polymers and Surfactants. Wiley Interscience, New Jersey.
5. Crespi, C.L., 1995. Xenobiotic-metabolizing human cells as tools for pharmacological and toxicological research. Adv. Drug Res. 26, 179-235.
6. Davis, M.E., 2002. Non viral-gene delivery systems. Curr. Opin. Biotechnol. 13, 128-131.
7. Desfougères, Y., Croguennec, T., Lechevalier, V., Bouhallab, S., Nau, F., 2010. Charge and size drive spontaneous self-assembly of oppositely charged globular proteins into microspheres. J. Phys. Chem. B 114, 4138-4144.
8. Dobrovolskaia, M.A., Clogston, J.D., Neun, B.W., Hall, J.R.B., Patri, A.K., McNeil, S.E. Method for analysis of nanoparticle hemolytic properties in vitro. Nano Lett. 8, 2180-2187.
9. Fröhlich, E., Meindi, C., Roblegg, E., Griesbacher, A., Pieber, T.R., 2012. Cytotoxity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing. Nanotoxicology 6, 424-439.
10. Hawkins, M.J., Soon-Shiong, P., Desai, N., 2008. Protein nanoparticles as drug carriers in clinical medicine. Adv. Drug Deliv. Rev. 60, 876-885.
11. He, M., Zhao, Z., Yin, L., Tang, C., Yin, C., 2009. Hyaluronic acid coated poly(butyl cyanoacrylate) nanoparticles as anticancer drug carriers. Int. J. Pharm. 373, 165-173.
12. Hillegass, J.M., Shukla, A., Lathrop, S.A., MacPherson, M.B., Fukagawa, N.K., Mossman, B.T., 2009. Assessing nanotoxicity in cells in vitro, WIREs nanomed. Nanobiotechnology 2, 219-231.
13. Jondeau, A., Dahbi, L., Bani-Estivals, M.H., Chagnon, M.C., 2006. Evaluation of the sensitivity of three sublethal cytotoxicity assays in human HepG2 cell line using water contaminants. Toxicology 226, 218-228. (Pubitemid 44287171)
14. Kratz, F., 2008. Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. J. Control. Release 132, 171-183.
15. Lasic, D., 1997. Liposomes in Gene delivery. CRC Press, Boca Raton, FL.
16. Ledley, F.D., 1996. Pharmaceutical approach to somatic gene therapy. Pharm. Res. 13, 1595-1614. (Pubitemid 27000017)
17. Lesniak, A., Fenaroli, F., Monopoli, M.P., Aberg, C., Dawson, K.A., Salvati, A., 2012. Effects of the presence or absence of a protein corona on silica nanoparticle uptake and impact on cells. ACS Nano 6, 5845-5857.
18. 2 nanoparticles to erythrocyte in vitro. Food Chem. Toxicol. 46, 3623-3631.
19. Lindman, B., Dias, R.S., Miguel, M.G., Morán, M.C., Costa, D., 2009. Manipulation of DNA by surfactants. In: Platikanov, D., Exerowa, D. (Eds.), Highlights in Colloid Science. Wiley-VCH, Weinheim.
20. Lindman, B., Dias, R.S., Miguel, M.G., Morán, M.C., Costa, D., 2010. DNA-surfactants systems: particles, gels and nanostructures. In: Nanoscience: Colloidal and Interfacial Aspects. CRC Press Taylor & Francis, Boca Raton, FL.
21. Lv, Y.H., Chen, X.G., Wang, Q.Z., Wang, Y., Zhang, J., Liu, C.S., Liu, C.G., Meng, X.H., Yu, L.J., 2007. Synthesis and characterization of chitosan-based biomaterials modified with different active groups and their relationship with cytotoxicity. J. Wuhan Univ. Technol.-Mater. Sci. Ed. 22, 695-700.
22. Martinez, V., Corsini, E., Mitjans, M., Pinazo, A., Vinardell, M.P., 2006. Evaluation of eye and skin irritation of argininge-derivative surfactants using different in vitro endpoints as alternatives to the in vivo assays. Toxicol. Lett. 164, 259-267. (Pubitemid 43786337)
23. Morán, M.C., Alonso, T., Lima, F.S., Vinardell, M.P., Miguel, M.G., Lindman, B., 2012. Counter-ion effect on surfactant-DNA gel particles as controlled DNA delivery systems. Soft Matter 8, 3200-3211.
24. Morán, M.C., Pais, A.A.C.C., Ramalho, A., Miguel, M.G., Lindman, B., 2009a. Mixed protein carriers for modulating DNA release. Langmuir 25, 10263-10270.
25. Morán, M.C., Baptista, F.R., Ramalho, A., Miguel, M.G., Lindman, B., 2009b. DNA gel nanoparticles: preparation and controlling the size. Soft Matter 5, 2538-2542.
26. Morán, M.C., Miguel, M.G., Lindman, B., 2010. DNA gel particles. Soft Matter 6, 3143-3156.
27. Morán, M.C., Mitjans, M., Martínez, V., Nogueira, D.R., Vinardell, M.P., 2013. Current directions in DNA gel particles. In: Muñoz-Torrero, D., Cortés, A., Mariño, E.L. (Eds.), Recent Advances in Pharmaceutical Sciences III. Transworld Research Network, Kerala, India.
28. Morán, M.C., Miguel, M.G., Lindman, B., 2007a. DNA gel particles: particle preparation and release characteristics. Langmuir 23, 6478-6481. (Pubitemid 46943466)
29. Morán, M.C., Miguel, M.G., Lindman, B., 2007b. Surfactant-DNA gel particles: formation and release characteristics. Biomacromolecules 8, 3886-3892.
30. Mosmann, T., 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63. (Pubitemid 14203433)
31. Pack, D.W., Putnam, D., Langer, R., 2000. Design of imidazole-containing endosomolytic biopolymers for gene delivery. Biotechnol. Bioeng. 67, 217-223. (Pubitemid 30029783)
32. Rao, G., Yadava, P., Hughes, 2007. Rationally designed synthetic vectors for gene delivery. J. Open Drug Deliv. J. 1, 7-19.
33. Rao, S.B., Sharma, C.P., 1997. Use of chitosan as a biomaterial: studies on its safety and hemostatic potential. J. Biomed. Mater. Res. 34, 21-28. (Pubitemid 26425214)
34. Rhaese, S., Briesen, H., Rübsamen-Waigmann, H., Kreuter, J., Langer, K., 2003. Human serum albumin-polyethylenimine nanoparticles for gene delivery. J. Control. Release 92, 199-208. (Pubitemid 37130132)
35. Rejman, J., Oberle, V., Zuhorn, I.S., Hoekstra, D., 2004. Size-dependent internalization of particles via the pathways of chathrin- and caveolae-mediated endocytosis. Biochem. J. 377, 159-169. (Pubitemid 38114443)
36. Robbens, J., Vanparys, C., Nobels, I., Blust, R., Hoecke, K.V., Janssen, C., Schamphelaere, K.D., Roland, K., Blanchard, G., Silvestre, F., Gillardin, V., Kestemont, P., Anthonissen, R., Toussaint, O., Vankoningsloo, S., Saout, C., Alfaro-Moreno, E., Hoet, P., Gonzalez, L., Dubruel, P., Troisfontaines, P., 2010. Eco-, geno-, and human toxicology of bio-active nanoparticles for biomedical applications. Toxicology 269, 170-181.
37. Saenger, W., 1984. Principles of Nuclei Structure. Springer-Verlag, New York.
38. Sambrook, J., Fritsch, E.F., Maniatis, E.F., 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, New York.
39. Venkatesan, P., Puvvada, N., Dash, R., Prashanth Kumar, B.N., Sarkar, D., Azab, B., Pathak, A., Kundu, S.C., Fisher, P.B., Mandal, M., 2011. The potential of celecoxib-loaded hydroxyapatite-chitosan nanocomposite for the treatment of colon cancer. Biomaterials 32, 3794-3806.