-
1
-
-
80052668582
-
Interaction of tumour cells with the microenvironment
-
Hendrik Ungefroren, Susanne Sebens, Daniel Seidl, Hendrik Lehnert, Ralf Hass. Interaction of tumour cells with the microenvironment. Cell Communication and Signaling. 2011;9:1-8
-
(2011)
Cell Communication and Signaling.
, vol.9
, pp. 1-8
-
-
Ungefroren, H.1
Sebens, S.2
Seidl, D.3
Lehnert, H.4
Hass, R.5
-
2
-
-
0035901090
-
Inflammation and cancer: Back to Virchow?
-
Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet. 2001; 357: 539-45.
-
(2001)
Lancet.
, vol.357
, pp. 539-545
-
-
Balkwill, F.1
Mantovani, A.2
-
4
-
-
77954951446
-
The polarization of immune cells in the tumour environment by TGF beta
-
Flavell RA, Sanjabis, Wrzesinski SH, Licona-Limon P. The polarization of immune cells in the tumour environment by TGF beta. Nat Rev Immunol. 2010; 10 (8):554-57.
-
(2010)
Nat Rev Immunol.
, vol.10
, Issue.8
, pp. 554-557
-
-
Flavell, R.A.1
Sanjabis, W.S.H.2
Licona-Limon, P.3
-
5
-
-
84655169986
-
The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma
-
Sirica AE. The role of cancer-associated myofibroblasts in intrahepatic cholangiocarcinoma. Nat. Rev. Gastroenterol. Hepatol. 2012; 1:44-54.
-
(2012)
Nat. Rev. Gastroenterol. Hepatol.
, vol.1
, pp. 44-54
-
-
Sirica, A.E.1
-
6
-
-
84859015041
-
Tumour Microenvironment in the Brain
-
Mihaela Lorger. Tumour Microenvironment in the Brain. Cancers. 2012; 4:218-43.
-
(2012)
Cancers.
, vol.4
, pp. 218-243
-
-
Lorger, M.1
-
7
-
-
35148881028
-
Drug resistance and the solid tumour microenvironment
-
Tredan, O, Carlos M, Galimarini, Krupa Patel, Lan F. Drug resistance and the solid tumour microenvironment. J Natl Cancer Inst. 2007; 99(19):1441-54.
-
(2007)
J Natl Cancer Inst.
, vol.99
, Issue.19
, pp. 1441-1454
-
-
Tredan, O.1
Carlos, M.2
Galimarini3
Patel, K.4
Lan, F.5
-
8
-
-
58149334773
-
A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer
-
Farmer P, Bonnefoi H, Anderle P, Cameron D, Aguet M, et al. A stroma-related gene signature predicts resistance to neoadjuvant chemotherapy in breast cancer. Nat Med. 2009; 15(1): 68-74.
-
(2009)
Nat Med.
, vol.15
, Issue.1
, pp. 68-74
-
-
Farmer, P.1
Bonnefoi, H.2
Anderle, P.3
Cameron, D.4
Aguet, M.5
-
9
-
-
84883879720
-
Tumour Microenvironment
-
Tonya C. Walser, Jane Yanagawa, Edward Garon, Jay M. Lee, and Steven M. Dubinett. Tumour Microenvironment. Current Clinical Oncology. 2010; 28-69.
-
(2010)
Current Clinical Oncology
, pp. 28-69
-
-
Walser, T.C.1
Yanagawa, J.2
Garon, E.3
Lee, J.M.4
Dubinett, S.M.5
-
10
-
-
77956460390
-
Environmental control of invasiveness and metastatic dissemination of tumour cells: The role of tumour cell-host cell interactions
-
Calorini L, Bianchini F: Environmental control of invasiveness and metastatic dissemination of tumour cells: the role of tumour cell-host cell interactions. Cell Commun Signal. 2010;8:24.
-
(2010)
Cell Commun Signal.
, vol.8
, pp. 24
-
-
Calorini, L.1
Bianchini, F.2
-
11
-
-
77957798181
-
Macrophages may promote cancer growth via a GM-CSF/ HB-EGF paracrine loop that is enhanced by CXCL12
-
Rigo A, Gottardi M, Zamò A, Mauri P, Bonifacio M, Krampera M, Damiani E, Pizzolo G, Vinante F: Macrophages may promote cancer growth via a GM-CSF/ HB-EGF paracrine loop that is enhanced by CXCL12. Mol Cancer. 2010; 9:273.
-
(2010)
Mol Cancer.
, vol.9
, pp. 273
-
-
Rigo, A.1
Gottardi, M.2
Zamò, A.3
Mauri, P.4
Bonifacio, M.5
Krampera, M.6
Damiani, E.7
Pizzolo, G.8
Vinante, F.9
-
12
-
-
14844331400
-
Dendritic-cell-based therapeutic vaccination against cancer
-
Nestle FO, Farkas A, Conrad C. Dendritic-cell-based therapeutic vaccination against cancer. Curr Opin Immunol. 2005;17:163-69.
-
(2005)
Curr Opin Immunol.
, vol.17
, pp. 163-169
-
-
Nestle, F.O.1
Farkas, A.2
Conrad, C.3
-
13
-
-
77949886426
-
Hospicells (ascites-derived stromal cells) promote tumourigenicity and angiogenesis
-
Pasquet, M, Golzio M, Mery, E, Rafii, A, Benabbou, N. Mirshahi, P.; et al. Hospicells (ascites-derived stromal cells) promote tumourigenicity and angiogenesis. Int. J. Cancer. 2010, 9, 2090-2101.
-
(2010)
Int. J. Cancer.
, vol.9
, pp. 2090-2101
-
-
Pasquet, M.1
Golzio, M.2
Mery, E.3
Rafii, A.4
Benabbou, N.5
Mirshahi, P.6
-
14
-
-
79956328903
-
Molecular mechanisms and clinical applications of angiogenesis
-
Carmeliet P, Jain RK. Molecular mechanisms and clinical applications of angiogenesis. Nature. 2011;7347: 298-307
-
(2011)
Nature.
, vol.7347
, pp. 298-307
-
-
Carmeliet, P.1
Jain, R.K.2
-
15
-
-
84865036227
-
Implication of Tumour Microenvironment in Chemoresistance: Tumour-Associated Stromal CellsProtect Tumour Cells from Cell Death
-
Magali Castells, Benoît Thibault, Jean-Pierre Delord, Bettina Couderc. Implication of Tumour Microenvironment in Chemoresistance: Tumour-Associated Stromal CellsProtect Tumour Cells from Cell Death. Int. J. Mol. Sci. 2012; 13, 9545-71.
-
(2012)
Int. J. Mol. Sci.
, vol.13
, pp. 9545-9571
-
-
Castells, M.1
Thibault, B.2
Delord, J.-P.3
Couderc, B.4
-
16
-
-
34250863385
-
Transforming growth factor-beta signaling in prostate stromal cells supports prostate carcinoma growth by up-regulating stromal genes related to tissue remodeling
-
Verona, E. V, Elkahloun AG, Yang J, Bandyopadhyay A, Yeh IT, Sun LZ. Transforming growth factor-beta signaling in prostate stromal cells supports prostate carcinoma growth by up-regulating stromal genes related to tissue remodeling. Cancer Res. 2007; 67(12):5737-46.
-
(2007)
Cancer Res.
, vol.67
, Issue.12
, pp. 5737-5746
-
-
Verona, E.V.1
Elkahloun, A.G.2
Yang, J.3
Bandyopadhyay, A.4
Yeh, I.T.5
Sun, L.Z.6
-
17
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumour growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedes F, Delaunay T, Naeem R., et al., Stromal fibroblasts present in invasive human breast carcinomas promote tumour growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 2005; 121: 335-48.
-
(2005)
Cell.
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedes, F.4
Delaunay, T.5
Naeem, R.6
-
18
-
-
47249119717
-
TGF-beta receptor kinase inhibitor LY2109761 reverses the anti-apoptotic effects of TGFbeta1 in myelo-monocytic leukaemic cells co-cultured with stromal cells
-
Xu Y, Tabe Y, Jin L, Watt J, McQueen T, Ohsaka A, Andreeff, M.;et al. TGF-beta receptor kinase inhibitor LY2109761 reverses the anti-apoptotic effects of TGFbeta1 in myelo-monocytic leukaemic cells co-cultured with stromal cells. Br. J. Haematol. 2008; 2:192-201.
-
(2008)
Br. J. Haematol.
, vol.2
, pp. 192-201
-
-
Xu, Y.1
Tabe, Y.2
Jin, L.3
Watt, J.4
McQueen, T.5
Ohsaka, A.6
Andreeff, M.7
-
19
-
-
82455210969
-
Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells
-
Fingas CD, Bronk SF, Werneburg NW, Mott JL, Guicciardi ME, Cazanave SC. Mertens, et al. Myofibroblast-derived PDGF-BB promotes Hedgehog survival signaling in cholangiocarcinoma cells. Hepatology. 2011; 6:2076-88.
-
(2011)
Hepatology.
, vol.6
, pp. 2076-2088
-
-
Fingas, C.D.1
Bronk, S.F.2
Werneburg, N.W.3
Mott, J.L.4
Guicciardi, M.E.5
Mertens, C.S.C.6
-
20
-
-
38849202330
-
Functions of paracrine PDGF signaling in the proangiogenic tumour stroma revealed by pharmacological targeting
-
Kristian Pietras, Jessica Pahler, Gabriele Bergers, Douglas Hanahan. Functions of paracrine PDGF signaling in the proangiogenic tumour stroma revealed by pharmacological targeting. PLoS Med. 2008; 5(1): 19.
-
(2008)
PLoS Med.
, vol.5
, Issue.1
, pp. 19
-
-
Pietras, K.1
Pahler, J.2
Bergers, G.3
Hanahan, D.4
-
21
-
-
80053442440
-
Lymph node stromal cells enhance drug-resistant colon cancer cell tumour formation through SDF-1alpha/CXCR4 paracrine signaling
-
Margolin DA, Silinsky J, Grimes C, Spencer N, Aycock, M.; Green, H.;et al. Lymph node stromal cells enhance drug-resistant colon cancer cell tumour formation through SDF-1alpha/CXCR4 paracrine signaling. Neoplasia. 2011; 9:874-86.
-
(2011)
Neoplasia.
, vol.9
, pp. 874-886
-
-
Margolin, D.A.1
Silinsky, J.2
Grimes, C.3
Spencer, N.4
Aycock, M.5
Green, H.6
-
22
-
-
77956472212
-
The role of the tissue microenvironment in the regulation of cancer cell motility and invasion
-
Brabek J, Mierke CT, Rosel D, Vesely P and Fabry B. The role of the tissue microenvironment in the regulation of cancer cell motility and invasion. Cell Commun Signal. 2010; 8: 22.
-
(2010)
Cell Commun Signal.
, vol.8
, pp. 22
-
-
Brabek, J.1
Mierke, C.T.2
Rosel, D.3
Vesely, P.4
Fabry, B.5
-
23
-
-
80052668582
-
Interaction of tumour cells with the microenvironment
-
Ungefroren H, Sebens S, Seidl D, Lehnert H, Hass R. Interaction of tumour cells with the microenvironment. Cell Commun Signal. 2011; 9:18.
-
(2011)
Cell Commun Signal.
, vol.9
, pp. 18
-
-
Ungefroren, H.1
Sebens, S.2
Seidl, D.3
Lehnert, H.4
Hass, R.5
-
24
-
-
70450222098
-
Matrix crosslinking forces tumour progression by enhancing integrin signaling
-
Levental, K. R, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT., et al., Matrix crosslinking forces tumour progression by enhancing integrin signaling. Cell. 2009; 139(5): 891-906.
-
(2009)
Cell.
, vol.139
, Issue.5
, pp. 891-906
-
-
Levental, K.R.1
Yu, H.2
Kass, L.3
Lakins, J.N.4
Egeblad, M.5
Erler, J.T.6
-
25
-
-
35748970483
-
Tumour microvasculature and microenvironment: Targets for anti-angiogenesis and normalization
-
Fukumura, D. and R.K. Jain, Tumour microvasculature and microenvironment: targets for anti-angiogenesis and normalization. Microvasc Res. 2007; 74(2-3): 72-84.
-
(2007)
Microvasc Res.
, vol.74
, Issue.2-3
, pp. 72-84
-
-
Fukumura, D.1
Jain, R.K.2
-
26
-
-
84863229849
-
Matrix rigidity regulates a switch between TGF-beta1-induced apoptosis and epithelial-mesenchymal transition
-
Leight JL, Wozniak MA, Chen S, Lynch ML and Chen CS. Matrix rigidity regulates a switch between TGF-beta1-induced apoptosis and epithelial-mesenchymal transition. Mol Biol Cell. 2012; 23: 781-91.
-
(2012)
Mol Biol Cell.
, vol.23
, pp. 781-791
-
-
Leight, J.L.1
Wozniak, M.A.2
Chen, S.3
Lynch, M.L.4
Chen, C.S.5
-
27
-
-
79958191830
-
Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways
-
Rohwer N, Cramer T. Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways. Drug Resist. Updat 2011; 3:191-201.
-
(2011)
Drug Resist. Updat
, vol.3
, pp. 191-201
-
-
Rohwer, N.1
Cramer, T.2
-
28
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006; 3:177-85.
-
(2006)
Cell Metab.
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
29
-
-
84859385707
-
Hypoxia-induced autophagy promotes tumour cell survival and adaptation to antiangiogenic treatment in glioblastoma
-
Hu YL, DeLay M, Jahangiri A, Molinaro AM, Rose SD, Carbonell WS, Aghi MK. Hypoxia-induced autophagy promotes tumour cell survival and adaptation to antiangiogenic treatment in glioblastoma. Cancer Res. 2012; 72(7):1773-83.
-
(2012)
Cancer Res.
, vol.72
, Issue.7
, pp. 1773-1783
-
-
Hu, Y.L.1
DeLay, M.2
Jahangiri, A.3
Molinaro, A.M.4
Rose, S.D.5
Carbonell, W.S.6
Aghi, M.K.7
-
30
-
-
69249087671
-
Environment-mediated drug resistance: A major contributor to minimal residual disease
-
Meads MB, Gatenby RA, Dalton WS. Environment-mediated drug resistance: A major contributor to minimal residual disease. Nat. Rev. Cancer 2009; 9: 665-74.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 665-674
-
-
Meads, M.B.1
Gatenby, R.A.2
Dalton, W.S.3
-
31
-
-
80052592013
-
Mesenchymal stemncells induce resistance to chemotherapy through the release of platinum-induced fatty acids
-
Roodhart, JM, Daenen LG, Stigter EC, Prins HJ, Gerrits J, Houthuijzen JM, et al. Mesenchymal stemncells induce resistance to chemotherapy through the release of platinum-induced fatty acids. Cancer Cell. 2011; 3:370-83.
-
(2011)
Cancer Cell.
, vol.3
, pp. 370-383
-
-
Roodhart, J.M.1
Daenen, L.G.2
Stigter, E.C.3
Prins, H.J.4
Gerrits, J.5
Houthuijzen, J.M.6
-
32
-
-
47949089077
-
VEGF-targeted therapy: Mechanisms of anti-tumour activity
-
Ellis LM, Hicklin DJ. VEGF-targeted therapy: mechanisms of anti-tumour activity. Nat Rev Cancer. 2008; 8: 579-91.
-
(2008)
Nat Rev Cancer.
, vol.8
, pp. 579-591
-
-
Ellis, L.M.1
Hicklin, D.J.2
-
33
-
-
79952748179
-
Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study
-
Bauerle T, Komljenovic D, Merz M, Berger MR, Goodman SL, Semmler W. Cilengitide inhibits progression of experimental breast cancer bone metastases as imaged noninvasively using VCT, MRI and DCE-MRI in a longitudinal in vivo study. Int J Cancer. 2011; 128:2453-62.
-
(2011)
Int J Cancer.
, vol.128
, pp. 2453-2462
-
-
Bauerle, T.1
Komljenovic, D.2
Merz, M.3
Berger, M.R.4
Goodman, S.L.5
Semmler, W.6
-
34
-
-
0036498790
-
Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas
-
Reardon DA, Akabani G, Coleman RE, Allan H, Friedman, Henry S Friedman, James E Herndon II., et al., Phase II trial of murine (131)I-labeled antitenascin monoclonal antibody 81C6 administered into surgically created resection cavities of patients with newly diagnosed malignant gliomas. J Clin Oncol. 2002; 20:1389-97.
-
(2002)
J Clin Oncol.
, vol.20
, pp. 1389-1397
-
-
Reardon, D.A.1
Akabani, G.2
Coleman, R.E.3
Allan, H.4
Friedman, H.S.F.5
Herndon II, J.E.6
-
35
-
-
63849261384
-
Expression of the oncofetal ED-B-containing fibronectin isoform in hematologic tumours enables ED-B-targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients
-
Sauer S, Erba PA, Petrini M, Menrad A, Giorannoni L, Grana C, et al. Expression of the oncofetal ED-B-containing fibronectin isoform in hematologic tumours enables ED-B-targeted 131I-L19SIP radioimmunotherapy in Hodgkin lymphoma patients. Blood. 2009; 113: 2265-74.
-
(2009)
Blood.
, vol.113
, pp. 2265-2274
-
-
Sauer, S.1
Erba, P.A.2
Petrini, M.3
Menrad, A.4
Giorannoni, L.5
Grana, C.6
-
36
-
-
69949096727
-
Mechanism of action of lenalidomide in hematological malignancies
-
Kotla V, Goel S, Nischal S, Heuck C, Vivek K, Das B, et al. Mechanism of action of lenalidomide in hematological malignancies. J Hematol Oncol. 2009; 2: 36.
-
(2009)
J Hematol Oncol.
, vol.2
, pp. 36
-
-
Kotla, V.1
Goel, S.2
Nischal, S.3
Heuck, C.4
Vivek, K.5
Das, B.6
-
37
-
-
70349782995
-
Early response to COX-2 inhibitors as a predictor of overall response in osteoarthritis: Pooled results from two identical trials comparing etoricoxib, celecoxib and placebo
-
Bingham CO III, Smugar SS, Wang H, Tershakove AM. Early response to COX-2 inhibitors as a predictor of overall response in osteoarthritis: pooled results from two identical trials comparing etoricoxib, celecoxib and placebo. Rheumatology. 2009; 48:1122-27.
-
(2009)
Rheumatology.
, vol.48
, pp. 1122-1127
-
-
Bingham III, C.O.1
Smugar, S.S.2
Wang, H.3
Tershakove, A.M.4
-
38
-
-
0036114348
-
A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis
-
Phillips RK, Wallace MH, Lynch PM, Hawk E, Gordon GB, Saunders BP., et al., A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis. Gut. 2002; 50: 857-60.
-
(2002)
Gut.
, vol.50
, pp. 857-860
-
-
Phillips, R.K.1
Wallace, M.H.2
Lynch, P.M.3
Hawk, E.4
Gordon, G.B.5
Saunders, B.P.6
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