Potential protective effect of biphasic electrical stimulation against growth factor-deprived apoptosis on olfactory bulb neural progenitor cells through the brain-derived neurotrophic factor-phosphatidylinositol 3′-kinase/Akt pathway

Experimental Biology and Medicine

Volumn 238, Issue 7, 2013, Pages 951-959

  Wang, Menghang ^a   Li, Ping ^a   Liu, Meili ^a   Song, Wei ^a   Wu, Qian ^a   Fan, Yubo ^a  

^a BEIHANG UNIVERSITY   (China)

Author keywords

BDNF PI3K Akt pathway; biphasic electrical stimulation; growth factor deprived apoptosis; neural precursor cells; stem cell therapy

Indexed keywords

NEUROTROPHIC FACTOR; NEUROTROPHIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; GLIAL FIBRILLARY ACIDIC PROTEIN; WORTMANNIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; ELECTROSTIMULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOCYTOCHEMISTRY; NEURAL STEM CELL; NONHUMAN; OLFACTORY BULB; RAT; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ANIMAL EXPERIMENT; CELL SURVIVAL; CELL VIABILITY; IC50; MTT ASSAY; NEWBORN; PROTEIN EXPRESSION;

BDNF-PI3K/AKT PATHWAY; BIPHASIC ELECTRICAL STIMULATION; GROWTH FACTOR-DEPRIVED APOPTOSIS; NEURAL PRECURSOR CELLS; STEM CELL THERAPY;

ANIMALS; APOPTOSIS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; ELECTRIC STIMULATION THERAPY; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; NEURAL STEM CELLS; OLFACTORY BULB; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STEM CELL TRANSPLANTATION;

EID: 84883819446     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1177/1535370213494635     Document Type: Article

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