An LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardia

Journal of Cardiovascular Electrophysiology

Volumn 24, Issue 9, 2013, Pages 1021-1027

  Nawathe, Pooja A ^a   Kryukova, Yelena ^a   Oren, Ronit V ^b   Milanesi, Raffaella ^c   Clancy, Colleen E ^b   Lu, Jonathan T ^a   Moss, Arthur J ^d   Difrancesco, Dario ^c   Robinson, Richard B ^a  

^a NewYork Presbyterian Hospital   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

HCN2; HCN4; KCNE2; long QT syndrome 6; M54T mutation; MiRP1; pacemaker current; sinus bradycardia; sinus node dysfunction

Indexed keywords

POTASSIUM CHANNEL KCNE2;

ADULT; ANIMAL CELL; ARTICLE; CASE REPORT; COMPUTER SIMULATION; GENE MUTATION; HEART MUSCLE CELL; HUMAN; KINETICS; LONG QT SYNDROME; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SEQUENCE ANALYSIS; SINUS BRADYCARDIA;

HCN2; HCN4; KCNE2; LONG-QT SYNDROME 6; M54T MUTATION; MIRP1; PACEMAKER CURRENT; SINUS BRADYCARDIA; SINUS NODE DYSFUNCTION;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL CLOCKS; BRADYCARDIA; CELLS, CULTURED; COCULTURE TECHNIQUES; DOWN-REGULATION; HUMANS; MALE; MIDDLE AGED; MUTATION; POTASSIUM CHANNELS, VOLTAGE-GATED; RATS; RATS, WISTAR;

EID: 84883802931     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/jce.12163     Document Type: Article

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