메뉴 건너뛰기




Volumn 4, Issue 5, 2013, Pages 349-356

Flexible and dynamic nucleosome fiber in living mammalian cells

Author keywords

30 nm chromatin fiber; Fluorescence correlation spectroscopy (FCS); Interphase chromatin; Irregular folding; Mitotic chromosomes; Monte Carlo computer simulations; Nucleosome fiber (10 nm fiber); Nucleosome fluctuation; Polymer melt; Single nucleosome imaging; Transcriptional regulation

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; GENOMIC DNA;

EID: 84883791067     PISSN: 19491034     EISSN: 19491042     Source Type: Journal    
DOI: 10.4161/nucl.26053     Document Type: Article
Times cited : (36)

References (49)
  • 1
    • 0016221697 scopus 로고
    • Chromatin structure: A repeating unit of histones and DNA
    • PMID:4825889
    • Kornberg RD. Chromatin structure: a repeating unit of histones and DNA. Science 1974; 184:868-71; PMID:4825889; http://dx.doi.org/10.1126/science. 184.4139.868
    • (1974) Science , vol.184 , pp. 868-871
    • Kornberg, R.D.1
  • 2
    • 0017251130 scopus 로고
    • Structural repeating units in chromatin. I. Evidence for their general occurrence
    • PMID:812708
    • Woodcock CL, Safer JP, Stanchfield JE. Structural repeating units in chromatin. I. Evidence for their general occurrence. Exp Cell Res 1976; 97:101-10; PMID:812708; http://dx.doi.org/10.1016/0014-4827(76)90659-5
    • (1976) Exp Cell Res , vol.97 , pp. 101-110
    • Woodcock, C.L.1    Safer, J.P.2    Stanchfield, J.E.3
  • 3
    • 0015964401 scopus 로고
    • Spheroid chromatin units (v bodies)
    • PMID:4128918
    • Olins AL, Olins DE. Spheroid chromatin units (v bodies). Science 1974; 183:330-2; PMID:4128918; http://dx.doi.org/10.1126/science.183.4122.330
    • (1974) Science , vol.183 , pp. 330-332
    • Olins, A.L.1    Olins, D.E.2
  • 4
    • 0000878535 scopus 로고
    • Solenoidal model for superstructure in chromatin
    • PMID:1064861
    • Finch JT, Klug A. Solenoidal model for superstructure in chromatin. Proc Natl Acad Sci U S A 1976; 73:1897-901; PMID:1064861; http://dx.doi. org/10.1073/pnas.73.6.1897
    • (1976) Proc Natl Acad Sci U S A , vol.73 , pp. 1897-1901
    • Finch, J.T.1    Klug, A.2
  • 5
    • 0021250785 scopus 로고
    • The higherorder structure of chromatin: Evidence for a helical ribbon arrangement
    • PMID:6736132
    • Woodcock CL, Frado LL, Rattner JB. The higherorder structure of chromatin: evidence for a helical ribbon arrangement. J Cell Biol 1984; 99:42-52; PMID:6736132; http://dx.doi.org/10.1083/ jcb.99.1.42
    • (1984) J Cell Biol , vol.99 , pp. 42-52
    • Woodcock, C.L.1    Frado, L.L.2    Rattner, J.B.3
  • 6
    • 0017583351 scopus 로고
    • A direct approach to the structure of eukaryotic chromosomes
    • PMID:98280
    • Sedat J, Manuelidis L. A direct approach to the structure of eukaryotic chromosomes. Cold Spring Harb Symp Quant Biol 1978; 42:331-50; PMID:98280; http://dx.doi.org/10.1101/SQB.1978.042.01.035
    • (1978) Cold Spring Harb Symp Quant Biol , vol.42 , pp. 331-350
    • Sedat, J.1    Manuelidis, L.2
  • 7
    • 0023368794 scopus 로고
    • A three-dimensional approach to mitotic chromosome structure: Evidence for a complex hierarchical organization
    • PMID:3112167
    • Belmont AS, Sedat JW, Agard DA. A three-dimensional approach to mitotic chromosome structure: evidence for a complex hierarchical organization. J Cell Biol 1987; 105:77-92; PMID:3112167; http:// dx.doi.org/10.1083/jcb.105.1.77
    • (1987) J Cell Biol , vol.105 , pp. 77-92
    • Belmont, A.S.1    Sedat, J.W.2    Agard, D.A.3
  • 8
    • 0022726854 scopus 로고
    • Cryoelectron microscopy of vitrified chromosomes in situ
    • PMID:3755397
    • McDowall AW, Smith JM, Dubochet J. Cryoelectron microscopy of vitrified chromosomes in situ. EMBO J 1986; 5:1395-402; PMID:3755397
    • (1986) EMBO J , vol.5 , pp. 1395-1402
    • McDowall, A.W.1    Smith, J.M.2    Dubochet, J.3
  • 9
    • 58149401194 scopus 로고    scopus 로고
    • Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ
    • PMID:19064912
    • Eltsov M, Maclellan KM, Maeshima K, Frangakis AS, Dubochet J. Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ. Proc Natl Acad Sci U S A 2008; 105:19732-7; PMID:19064912; http://dx.doi.org/10.1073/ pnas.0810057105
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 19732-19737
    • Eltsov, M.1    McLellan, K.M.2    Maeshima, K.3    Frangakis, A.S.4    Dubochet, J.5
  • 10
    • 77954819238 scopus 로고    scopus 로고
    • Chromatin structure: Does the 30-nm fibre exist in vivo?
    • PMID:20346642
    • Maeshima K, Hihara S, Eltsov M. Chromatin structure: does the 30-nm fibre exist in vivo? Curr Opin Cell Biol 2010; 22:291-7; PMID:20346642; http:// dx.doi.org/10.1016/j.ceb.2010.03.001
    • (2010) Curr Opin Cell Biol , vol.22 , pp. 291-297
    • Maeshima, K.1    Hihara, S.2    Eltsov, M.3
  • 11
    • 78650919361 scopus 로고    scopus 로고
    • Living without 30nm chromatin fibers
    • PMID:20926298
    • Fussner E, Ching RW, Bazett-Jones DP. Living without 30nm chromatin fibers. Trends Biochem Sci 2011; 36:1-6; PMID:20926298; http://dx.doi. org/10.1016/j.tibs.2010.09.002
    • (2011) Trends Biochem Sci , vol.36 , pp. 1-6
    • Fussner, E.1    Ching, R.W.2    Bazett-Jones, D.P.3
  • 12
    • 84859421494 scopus 로고    scopus 로고
    • Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure
    • PMID:22343941
    • Nishino Y, Eltsov M, Joti Y, Ito K, Takata H, Takahashi Y, Hihara S, Frangakis AS, Imamoto N, Ishikawa T, et al. Human mitotic chromosomes consist predominantly of irregularly folded nucleosome fibres without a 30-nm chromatin structure. EMBO J 2012; 31:1644-53; PMID:22343941; http://dx.doi. org/10.1038/emboj.2012.35
    • (2012) EMBO J , vol.31 , pp. 1644-1653
    • Nishino, Y.1    Eltsov, M.2    Joti, Y.3    Ito, K.4    Takata, H.5    Takahashi, Y.6    Hihara, S.7    Frangakis, A.S.8    Imamoto, N.9    Ishikawa, T.10
  • 14
    • 84868690351 scopus 로고    scopus 로고
    • Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres
    • PMID:22986547
    • Fussner E, Strauss M, Djuric U, Li R, Ahmed K, Hart M, Ellis J, Bazett-Jones DP. Open and closed domains in the mouse genome are configured as 10-nm chromatin fibres. EMBO Rep 2012; 13:992-6; PMID:22986547; http://dx.doi.org/10.1038/ embor.2012.139
    • (2012) EMBO Rep , vol.13 , pp. 992-996
    • Fussner, E.1    Strauss, M.2    Djuric, U.3    Li, R.4    Ahmed, K.5    Hart, M.6    Ellis, J.7    Bazett-Jones, D.P.8
  • 15
    • 84885863242 scopus 로고    scopus 로고
    • Chromatin in a marine picoeukaryote is a disordered assemblage of nucleosomes
    • PMID:23818178
    • Gan L, Ladinsky MS, Jensen GJ. Chromatin in a marine picoeukaryote is a disordered assemblage of nucleosomes. Chromosoma 2013; PMID:23818178; http://dx.doi.org/10.1007/s00412-013-0423-z
    • (2013) Chromosoma
    • Gan, L.1    Ladinsky, M.S.2    Jensen, G.J.3
  • 17
    • 78650528229 scopus 로고    scopus 로고
    • Fluorescence correlation spectroscopy in vivo
    • Mütze J, Ohrt T, Schwille P. Fluorescence correlation spectroscopy in vivo. Laser & Photonics Reviews 2011; 5:52-67; http://dx.doi.org/10.1002/ lpor.200910041
    • (2011) Laser & Photonics Reviews , vol.5 , pp. 52-67
    • Mütze, J.1    Ohrt, T.2    Schwille, P.3
  • 18
    • 0035033890 scopus 로고    scopus 로고
    • Autofluorescent proteins in singlemolecule research: Applications to live cell imaging microscopy
    • PMID:11325739
    • Harms GS, Cognet L, Lommerse PH, Blab GA, Schmidt T. Autofluorescent proteins in singlemolecule research: applications to live cell imaging microscopy. Biophys J 2001; 80:2396-408; PMID:11325739; http://dx.doi.org/10.1016/S0006-3495(01)76209-1
    • (2001) Biophys J , vol.80 , pp. 2396-2408
    • Harms, G.S.1    Cognet, L.2    Lommerse, P.H.3    Blab, G.A.4    Schmidt, T.5
  • 19
    • 0037874731 scopus 로고    scopus 로고
    • Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy
    • PMID:10698931
    • Schütz GJ, Kada G, Pastushenko VP, Schindler H. Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy. EMBO J 2000; 19:892-901; PMID:10698931; http://dx.doi.org/10.1093/emboj/19.5.892
    • (2000) EMBO J , vol.19 , pp. 892-901
    • Schütz, G.J.1    Kada, G.2    Pastushenko, V.P.3    Schindler, H.4
  • 20
    • 0033779765 scopus 로고    scopus 로고
    • Single-molecule imaging of EGFR signalling on the surface of living cells
    • PMID:10707088
    • Sako Y, Minoghchi S, Yanagida T. Single-molecule imaging of EGFR signalling on the surface of living cells. Nat Cell Biol 2000; 2:168-72; PMID:10707088; http://dx.doi.org/10.1038/35004044
    • (2000) Nat Cell Biol , vol.2 , pp. 168-172
    • Sako, Y.1    Minoghchi, S.2    Yanagida, T.3
  • 22
    • 49349114529 scopus 로고    scopus 로고
    • Reaction Brownian dynamics and the effect of spatial fluctuations on the gain of a push-pull network
    • PMID:18698893
    • Morelli MJ, ten Wolde PR. Reaction Brownian dynamics and the effect of spatial fluctuations on the gain of a push-pull network. J Chem Phys 2008; 129:054112; PMID:18698893; http://dx.doi. org/10.1063/1.2958287
    • (2008) J Chem Phys , vol.129 , pp. 054112
    • Morelli, M.J.1    ten Wolde, P.R.2
  • 24
    • 33751229633 scopus 로고    scopus 로고
    • Microenvironment and effect of energy depletion in the nucleus analyzed by mobility of multiple oligomeric EGFPs
    • PMID:16950841
    • Pack C, Saito K, Tamura M, Kinjo M. Microenvironment and effect of energy depletion in the nucleus analyzed by mobility of multiple oligomeric EGFPs. Biophys J 2006; 91:3921-36; PMID:16950841; http://dx.doi.org/10.1529/biophysj. 105.079467
    • (2006) Biophys J , vol.91 , pp. 3921-3936
    • Pack, C.1    Saito, K.2    Tamura, M.3    Kinjo, M.4
  • 26
    • 0033535323 scopus 로고    scopus 로고
    • Direct imaging of DNA in living cells reveals the dynamics of chromosome formation
    • PMID:10085283
    • Manders EM, Kimura H, Cook PR. Direct imaging of DNA in living cells reveals the dynamics of chromosome formation. J Cell Biol 1999; 144:813-21; PMID:10085283; http://dx.doi.org/10.1083/ jcb.144.5.813
    • (1999) J Cell Biol , vol.144 , pp. 813-821
    • Manders, E.M.1    Kimura, H.2    Cook, P.R.3
  • 27
    • 64549119730 scopus 로고    scopus 로고
    • Mapping eGFP oligomer mobility in living cell nuclei
    • PMID:19347038
    • Dross N, Spriet C, Zwerger M, Müller G, Waldeck W, Langowski J. Mapping eGFP oligomer mobility in living cell nuclei. PLoS One 2009; 4:e5041; PMID:19347038; http://dx.doi.org/10.1371/journal. pone.0005041
    • (2009) PLoS One , vol.4
    • Dross, N.1    Spriet, C.2    Zwerger, M.3    Müller, G.4    Waldeck, W.5    Langowski, J.6
  • 28
    • 72449204595 scopus 로고    scopus 로고
    • Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin
    • PMID:19927119
    • Bancaud A, Huet S, Daigle N, Mozziconacci J, Beaudouin J, Ellenberg J. Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin. EMBO J 2009; 28:3785-98; PMID:19927119; http://dx.doi.org/10.1038/ emboj.2009.340
    • (2009) EMBO J , vol.28 , pp. 3785-3798
    • Bancaud, A.1    Huet, S.2    Daigle, N.3    Mozziconacci, J.4    Beaudouin, J.5    Ellenberg, J.6
  • 29
    • 0242352409 scopus 로고    scopus 로고
    • Counting nucleosomes in living cells with a combination of fluorescence correlation spectroscopy and confocal imaging
    • PMID:14607115
    • Weidemann T, Wachsmuth M, Knoch TA, Müller G, Waldeck W, Langowski J. Counting nucleosomes in living cells with a combination of fluorescence correlation spectroscopy and confocal imaging. J Mol Biol 2003; 334:229-40; PMID:14607115; http://dx.doi. org/10.1016/j.jmb.2003.08.063
    • (2003) J Mol Biol , vol.334 , pp. 229-240
    • Weidemann, T.1    Wachsmuth, M.2    Knoch, T.A.3    Müller, G.4    Waldeck, W.5    Langowski, J.6
  • 30
    • 0042733701 scopus 로고    scopus 로고
    • High concentration of DNA in condensed chromatin
    • PMID:12897842
    • Daban JR. High concentration of DNA in condensed chromatin. Biochem Cell Biol 2003; 81:91-9; PMID:12897842; http://dx.doi.org/10.1139/o03-037
    • (2003) Biochem Cell Biol , vol.81 , pp. 91-99
    • Daban, J.R.1
  • 31
    • 53249103157 scopus 로고    scopus 로고
    • Genome organization: Balancing stability and plasticity
    • PMID:18722483
    • Wachsmuth M, Caudron-Herger M, Rippe K. Genome organization: balancing stability and plasticity. Biochim Biophys Acta 2008; 1783:2061-79; PMID:18722483; http://dx.doi.org/10.1016/j.bbamcr. 2008.07.022
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 2061-2079
    • Wachsmuth, M.1    Caudron-Herger, M.2    Rippe, K.3
  • 32
    • 69149097213 scopus 로고    scopus 로고
    • How proteins squeeze through polymer networks: A Cartesian lattice study
    • PMID:19691409
    • Wedemeier A, Merlitz H, Wu CX, Langowski J. How proteins squeeze through polymer networks: a Cartesian lattice study. J Chem Phys 2009; 131:064905; PMID:19691409; http://dx.doi. org/10.1063/1.3205100
    • (2009) J Chem Phys , vol.131 , pp. 064905
    • Wedemeier, A.1    Merlitz, H.2    Wu, C.X.3    Langowski, J.4
  • 33
    • 79952282147 scopus 로고    scopus 로고
    • Chromosome dynamics, molecular crowding, and diffusion in the interphase cell nucleus: A Monte Carlo lattice simulation study
    • PMID:21116704
    • Fritsch CC, Langowski J. Chromosome dynamics, molecular crowding, and diffusion in the interphase cell nucleus: a Monte Carlo lattice simulation study. Chromosome Res 2011; 19:63-81; PMID:21116704; http://dx.doi.org/10.1007/s10577-010-9168-1
    • (2011) Chromosome Res , vol.19 , pp. 63-81
    • Fritsch, C.C.1    Langowski, J.2
  • 34
    • 70350302609 scopus 로고    scopus 로고
    • Photoactivatable fluorescent proteins for diffractionlimited and super-resolution imaging
    • PMID:19836954
    • Lippincott-Schwartz J, Patterson GH. Photoactivatable fluorescent proteins for diffractionlimited and super-resolution imaging. Trends Cell Biol 2009; 19:555-65; PMID:19836954; http:// dx.doi.org/10.1016/j.tcb.2009.09.003
    • (2009) Trends Cell Biol , vol.19 , pp. 555-565
    • Lippincott-Schwartz, J.1    Patterson, G.H.2
  • 35
    • 38149137186 scopus 로고    scopus 로고
    • Chromatin movement visualized with photoactivable GFP-labeled histone H4
    • PMID:18021258
    • Wiesmeijer K, Krouwels IM, Tanke HJ, Dirks RW. Chromatin movement visualized with photoactivable GFP-labeled histone H4. Differentiation 2008; 76:83-90; PMID:18021258
    • (2008) Differentiation , vol.76 , pp. 83-90
    • Wiesmeijer, K.1    Krouwels, I.M.2    Tanke, H.J.3    Dirks, R.W.4
  • 36
    • 0035954427 scopus 로고    scopus 로고
    • Kinetics of core histones in living human cells: Little exchange of H3 and H4 and some rapid exchange of H2B
    • PMID:11425866
    • Kimura H, Cook PR. Kinetics of core histones in living human cells: little exchange of H3 and H4 and some rapid exchange of H2B. J Cell Biol 2001; 153:1341-53; PMID:11425866; http://dx.doi. org/10.1083/jcb.153.7.1341
    • (2001) J Cell Biol , vol.153 , pp. 1341-1353
    • Kimura, H.1    Cook, P.R.2
  • 37
    • 38749118235 scopus 로고    scopus 로고
    • Highly inclined thin illumination enables clear single-molecule imaging in cells
    • PMID:18176568
    • Tokunaga M, Imamoto N, Sakata-Sogawa K. Highly inclined thin illumination enables clear single-molecule imaging in cells. Nat Methods 2008; 5:159-61; PMID:18176568; http://dx.doi.org/10.1038/ nmeth1171
    • (2008) Nat Methods , vol.5 , pp. 159-161
    • Tokunaga, M.1    Imamoto, N.2    Sakata-Sogawa, K.3
  • 38
    • 35248816828 scopus 로고    scopus 로고
    • Precise particle tracking against a complicated background: Polynomial fitting with Gaussian weight
    • PMID:17928660
    • Rogers SS, Waigh TA, Zhao X, Lu JR. Precise particle tracking against a complicated background: polynomial fitting with Gaussian weight. Phys Biol 2007; 4:220-7; PMID:17928660; http://dx.doi. org/10.1088/1478-3975/4/3/008
    • (2007) Phys Biol , vol.4 , pp. 220-227
    • Rogers, S.S.1    Waigh, T.A.2    Zhao, X.3    Lu, J.R.4
  • 39
    • 84867294762 scopus 로고    scopus 로고
    • A benchmark for chromatin binding measurements in live cells
    • PMID:22844090
    • Mazza D, Abernathy A, Golob N, Morisaki T, McNally JG. A benchmark for chromatin binding measurements in live cells. Nucleic Acids Res 2012; 40:e119; PMID:22844090; http://dx.doi. org/10.1093/nar/gks701
    • (2012) Nucleic Acids Res , vol.40
    • Mazza, D.1    Abernathy, A.2    Golob, N.3    Morisaki, T.4    McNally, J.G.5
  • 40
    • 28444496753 scopus 로고    scopus 로고
    • Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope
    • PMID:16150965
    • Levi V, Ruan Q, Plutz M, Belmont AS, Gratton E. Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope. Biophys J 2005; 89:4275-85; PMID:16150965; http://dx.doi.org/10.1529/biophysj.105.066670.
    • (2005) Biophys J , vol.89 , pp. 4275-4285
    • Levi, V.1    Ruan, Q.2    Plutz, M.3    Belmont, A.S.4    Gratton, E.5
  • 41
    • 0033758019 scopus 로고    scopus 로고
    • Chromosome territories, interchromatin domain compartment, and nuclear matrix: An integrated view of the functional nuclear architecture
    • PMID:11186332
    • Cremer T, Kreth G, Koester H, Fink RH, Heintzmann R, Cremer M, Solovei I, Zink D, Cremer C. Chromosome territories, interchromatin domain compartment, and nuclear matrix: an integrated view of the functional nuclear architecture. Crit Rev Eukaryot Gene Expr 2000; 10:179-212; PMID:11186332; http://dx.doi.org/10.1615/ CritRevEukarGeneExpr.v10.i2.60
    • (2000) Crit Rev Eukaryot Gene Expr , vol.10 , pp. 179-212
    • Cremer, T.1    Kreth, G.2    Koester, H.3    Fink, R.H.4    Heintzmann, R.5    Cremer, M.6    Solovei, I.7    Zink, D.8    Cremer, C.9
  • 42
    • 0035316574 scopus 로고    scopus 로고
    • Chromosome territories, nuclear architecture and gene regulation in mammalian cells
    • PMID:11283701
    • Cremer T, Cremer C. Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nat Rev Genet 2001; 2:292-301; PMID:11283701; http://dx.doi.org/10.1038/35066075
    • (2001) Nat Rev Genet , vol.2 , pp. 292-301
    • Cremer, T.1    Cremer, C.2
  • 43
    • 0035141289 scopus 로고    scopus 로고
    • Twocolor fluorescence labeling of early and mid-to-late replicating chromatin in living cells
    • PMID:11272795
    • Schermelleh L, Solovei I, Zink D, Cremer T. Twocolor fluorescence labeling of early and mid-to-late replicating chromatin in living cells. Chromosome Res 2001; 9:77-80; PMID:11272795; http://dx.doi. org/10.1023/A:1026799818566
    • (2001) Chromosome Res , vol.9 , pp. 77-80
    • Schermelleh, L.1    Solovei, I.2    Zink, D.3    Cremer, T.4
  • 44
    • 28444450802 scopus 로고    scopus 로고
    • Spatio-temporal dynamics of genomic organization and function in the mammalian cell nucleus
    • PMID:16139341
    • Berezney R, Malyavantham KS, Pliss A, Bhattacharya S, Acharya R. Spatio-temporal dynamics of genomic organization and function in the mammalian cell nucleus. Adv Enzyme Regul 2005; 45:17-26; PMID:16139341; http://dx.doi.org/10.1016/j.advenzreg. 2005.02.013
    • (2005) Adv Enzyme Regul , vol.45 , pp. 17-26
    • Berezney, R.1    Malyavantham, K.S.2    Pliss, A.3    Bhattacharya, S.4    Acharya, R.5
  • 45
    • 33751258576 scopus 로고    scopus 로고
    • Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks
    • PMID:17115328
    • Albiez H, Cremer M, Tiberi C, Vecchio L, Schermelleh L, Dittrich S, Küpper K, Joffe B, Thormeyer T, von Hase J, et al. Chromatin domains and the interchromatin compartment form structurally defined and functionally interacting nuclear networks. Chromosome Res 2006; 14:707-33; PMID:17115328; http://dx.doi.org/10.1007/s10577-006-1086-x
    • (2006) Chromosome Res , vol.14 , pp. 707-733
    • Albiez, H.1    Cremer, M.2    Tiberi, C.3    Vecchio, L.4    Schermelleh, L.5    Dittrich, S.6    Küpper, K.7    Joffe, B.8    Thormeyer, T.9    von Hase, J.10
  • 47
    • 84861095603 scopus 로고    scopus 로고
    • Topological domains in mammalian genomes identified by analysis of chromatin interactions
    • PMID:22495300
    • Dixon JR, Selvaraj S, Yue F, Kim A, Li Y, Shen Y, Hu M, Liu JS, Ren B. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 2012; 485:376-80; PMID:22495300; http://dx.doi.org/10.1038/ nature11082
    • (2012) Nature , vol.485 , pp. 376-380
    • Dixon, J.R.1    Selvaraj, S.2    Yue, F.3    Kim, A.4    Li, Y.5    Shen, Y.6    Hu, M.7    Liu, J.S.8    Ren, B.9
  • 48
    • 84856747483 scopus 로고    scopus 로고
    • Three-dimensional folding and functional organization principles of the Drosophila genome
    • PMID:22265598
    • Sexton T, Yaffe E, Kenigsberg E, Bantignies F, Leblanc B, Hoichman M, Parrinello H, Tanay A, Cavalli G. Three-dimensional folding and functional organization principles of the Drosophila genome. Cell 2012; 148:458-72; PMID:22265598; http:// dx.doi.org/10.1016/j.cell.2012.01.010
    • (2012) Cell , vol.148 , pp. 458-472
    • Sexton, T.1    Yaffe, E.2    Kenigsberg, E.3    Bantignies, F.4    Leblanc, B.5    Hoichman, M.6    Parrinello, H.7    Tanay, A.8    Cavalli, G.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.