Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 50, 2008, Pages 19732-19737

  Eltsov, Mikhail ^a,c   MacLellan, Kirsty M ^a,d   Maeshima, Kazuhiro ^b   Frangakis, Achilleas S ^c,e   Dubochet, Jacques ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b RIKEN   (Japan)

^c EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^d UNIVERSITÉ PIERRE ET MARIE CURIE   (France)

^e GOETHE UNIVERSITY   (Germany)

Author keywords

Chromatin compaction; Chromosome structure; Contrast; Polymer melt; Transfer function; Vitreous sections

Indexed keywords

ARTICLE; CELL STRUCTURE; CHROMATIN STRUCTURE; CHROMOSOME; CRYOELECTRON MICROSCOPY; HELA CELL; HUMAN; HUMAN CELL; IMAGE ANALYSIS; METAPHASE; MITOSIS; NUCLEOSOME; PRIORITY JOURNAL; VITRIFICATION; CHROMATIN; CYTOPLASM; HUMAN CHROMOSOME; IMAGE PROCESSING; ULTRASTRUCTURE;

EUKARYOTA;

CHROMATIN; CHROMOSOMES, HUMAN; CRYOELECTRON MICROSCOPY; CYTOPLASM; HELA CELLS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MITOSIS; NUCLEOSOMES;

EID: 58149401194     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0810057105     Document Type: Article

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