MLL Becomes Functional through Intra-Molecular Interaction Not by Proteolytic Processing

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Yokoyama, Akihiko ^a   Ficara, Francesca ^b,c   Murphy, Mark J ^d   Meisel, Christian ^e   Hatanaka, Chikako ^f   Kitabayashi, Issay ^f   Cleary, Michael L ^d  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Milan Unit   (Italy)

^c HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^d STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^f NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MIXED LINEAGE LEUKEMIA PROTEIN;

ALLELE; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FETUS; FIBROBLAST; HEMATOPOIETIC STEM CELL; HOMOZYGOSITY; IN VIVO STUDY; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CELL PROLIFERATION; CELLS, CULTURED; EMBRYO, MAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEK293 CELLS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HISTONE-LYSINE N-METHYLTRANSFERASE; HUMANS; IN SITU HYBRIDIZATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; MUTATION; MYELOID-LYMPHOID LEUKEMIA PROTEIN; PROTEIN BINDING; PROTEOLYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84883767987     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073649     Document Type: Article

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