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Volumn 26, Issue 5, 2013, Pages 577-584

Pharmacological prospects in the treatment of Duchenne muscular dystrophy

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANTIOXIDANT; ATALUREN; BIGLYCAN; CALCIUM CHANNEL; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL 1; CORTICOSTEROID; CYCLIC AMP; CYCLIC GMP; CYCLOPHILIN D; DRISAPERSEN; DYSTROPHIN; ESTROGEN RECEPTOR; ETEPLIRSEN; GENTAMICIN; HORMONE RECEPTOR; MYOSTATIN; PREDNISOLONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RYANODINE RECEPTOR 1; SMALL NUCLEAR RNA; SOMATOMEDIN C; STEROID RECEPTOR; TAMOXIFEN; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; UNINDEXED DRUG; UTROPHIN; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 2;

EID: 84883766237     PISSN: 13507540     EISSN: 14736551     Source Type: Journal    
DOI: 10.1097/WCO.0b013e328364fbaf     Document Type: Review
Times cited : (49)

References (61)
  • 1
    • 0024332141 scopus 로고
    • Dystrophin abnormalities in Duchenne/Becker muscular dystrophy
    • Hoffman EP, Kunkel LM. Dystrophin abnormalities in Duchenne/Becker muscular dystrophy. Neuron 1989; 2:1019-1029.
    • (1989) Neuron , vol.2 , pp. 1019-1029
    • Hoffman, E.P.1    Kunkel, L.M.2
  • 2
    • 84861702473 scopus 로고    scopus 로고
    • Preclinical drug tests in the mdx mouse as a model of dystrophinopathies: An overview
    • DeLuca A. Preclinical drug tests in the mdx mouse as a model of dystrophinopathies: An overview. Acta Myol 2012; 31:40-47.
    • (2012) Acta Myol , vol.31 , pp. 40-47
    • DeLuca, A.1
  • 3
    • 84882662040 scopus 로고    scopus 로고
    • The mdx mouse model as a surrogate for Duchenne muscular dystrophy
    • Epub ahead of print]
    • Partridge TA. The mdx mouse model as a surrogate for Duchenne muscular dystrophy. FEBS J 2013. [Epub ahead of print]
    • (2013) FEBS J
    • Partridge, T.A.1
  • 4
    • 84859867996 scopus 로고    scopus 로고
    • Overview on DMD exon skipping
    • Aartsma-Rus A. Overview on DMD exon skipping. Methods Mol Biol 2012; 867:97-116.
    • (2012) Methods Mol Biol , vol.867 , pp. 97-116
    • Aartsma-Rus, A.1
  • 5
    • 84866342485 scopus 로고    scopus 로고
    • Pharmacological therapies for muscular dystrophies
    • Abdel-Hamid H, Clemens PR. Pharmacological therapies for muscular dystrophies. Curr Opin Neurol 2012; 25:604-608.
    • (2012) Curr Opin Neurol , vol.25 , pp. 604-608
    • Abdel-Hamid, H.1    Clemens, P.R.2
  • 6
    • 80052435477 scopus 로고    scopus 로고
    • Impending therapies for Duchenne muscular dystrophy
    • Partridge TA. Impending therapies for Duchenne muscular dystrophy. Curr Opin Neurol 2011; 24:415-422.
    • (2011) Curr Opin Neurol , vol.24 , pp. 415-422
    • Partridge, T.A.1
  • 7
    • 84878016335 scopus 로고    scopus 로고
    • Therapy for Duchenne muscular dystrophy: Renewed optimism from genetic approaches
    • Fairclough RJ, Wood MJ, Davies KE. Therapy for Duchenne muscular dystrophy: Renewed optimism from genetic approaches. Nat Rev Genet 2013; 14:373-378.
    • (2013) Nat Rev Genet , vol.14 , pp. 373-378
    • Fairclough, R.J.1    Wood, M.J.2    Davies, K.E.3
  • 8
    • 84876797554 scopus 로고    scopus 로고
    • Gene and cell-mediated therapies for muscular dystrophy
    • Konieczny P, Swiderski K, Chamberlain JS. Gene and cell-mediated therapies for muscular dystrophy. Muscle Nerve 2013; 47:649-663.
    • (2013) Muscle Nerve , vol.47 , pp. 649-663
    • Konieczny, P.1    Swiderski, K.2    Chamberlain, J.S.3
  • 10
    • 84866342088 scopus 로고    scopus 로고
    • Gene therapy for Duchenne muscular dystrophy
    • Verhaart IE, Aartsma-Rus A. Gene therapy for Duchenne muscular dystrophy. Curr Opin Neurol 2012; 25:588-596.
    • (2012) Curr Opin Neurol , vol.25 , pp. 588-596
    • Verhaart, I.E.1    Aartsma-Rus, A.2
  • 11
    • 84861716968 scopus 로고    scopus 로고
    • Drug treatment of Duchenne muscular dystrophy: Available evidence and perspectives
    • De Los Angeles Beytia L, Vry J, Kirschner J, et al. Drug treatment of Duchenne muscular dystrophy: Available evidence and perspectives. Acta Myol 2012; 31:4-8.
    • (2012) Acta Myol , vol.31 , pp. 4-8
    • De Los Angeles Beytia, L.1    Vry, J.2    Kirschner, J.3
  • 12
    • 84865794295 scopus 로고    scopus 로고
    • Read-through compound 13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy
    • Kayali R, Ku JM, Khitrov G, et al. Read-through compound 13 restores dystrophin expression and improves muscle function in the mdx mouse model for Duchenne muscular dystrophy. Hum Mol Genet 2012; 21:4007-4020.
    • (2012) Hum Mol Genet , vol.21 , pp. 4007-4020
    • Kayali, R.1    Ku, J.M.2    Khitrov, G.3
  • 13
    • 84861131280 scopus 로고    scopus 로고
    • Rescue of severely affected dystrophin/utrophin-deficient mice through SCAAV-U7snRNA-mediated exon skipping
    • Goyenvalle A, Babbs A, Wright J, et al. Rescue of severely affected dystrophin/utrophin-deficient mice through SCAAV-U7snRNA-mediated exon skipping. Hum Mol Genet 2012; 21:2559-2571.
    • (2012) Hum Mol Genet , vol.21 , pp. 2559-2571
    • Goyenvalle, A.1    Babbs, A.2    Wright, J.3
  • 14
    • 84869086454 scopus 로고    scopus 로고
    • Muscle function recovery in golden retriever muscular dystrophy after AAV1-U7 exon skipping
    • Vulin A, Barthelemy I, Goyenvalle A, et al. Muscle function recovery in golden retriever muscular dystrophy after AAV1-U7 exon skipping. Mol Ther 2012; 20:2120-2133.
    • (2012) Mol Ther , vol.20 , pp. 2120-2133
    • Vulin, A.1    Barthelemy, I.2    Goyenvalle, A.3
  • 15
    • 84856546632 scopus 로고    scopus 로고
    • Restoration of the dystrophin-associated glycoprotein complex after exon skipping therapy in Duchenne muscular dystrophy
    • Cirak S, Feng L, Anthony K, et al. Restoration of the dystrophin-associated glycoprotein complex after exon skipping therapy in Duchenne muscular dystrophy. Mol Ther 2012; 20:462-467.
    • (2012) Mol Ther , vol.20 , pp. 462-467
    • Cirak, S.1    Feng, L.2    Anthony, K.3
  • 16
    • 84862631856 scopus 로고    scopus 로고
    • Gene replacement therapies for Duchenne muscular dystrophy using adeno-associated viral vectors
    • Seto JT, Ramos JN, Muir L. Gene replacement therapies for Duchenne muscular dystrophy using adeno-associated viral vectors. Curr Gene Ther 2012; 12:139-151.
    • (2012) Curr Gene Ther , vol.12 , pp. 139-151
    • Seto, J.T.1    Ramos, J.N.2    Muir, L.3
  • 17
    • 84856515432 scopus 로고    scopus 로고
    • Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector
    • Bowles DE, McPhee SW, Li C, et al. Phase 1 gene therapy for Duchenne muscular dystrophy using a translational optimized AAV vector. Mol Ther 2012; 20:443-455.
    • (2012) Mol Ther , vol.20 , pp. 443-455
    • Bowles, D.E.1    McPhee, S.W.2    Li, C.3
  • 18
    • 84880278013 scopus 로고    scopus 로고
    • Trim proteins in therapeutic membrane repair of muscular dystrophy
    • Alloush J, Weisleder N. Trim proteins in therapeutic membrane repair of muscular dystrophy. JAMA Neurol 2013; 70:928-931.
    • (2013) JAMA Neurol , vol.70 , pp. 928-931
    • Alloush, J.1    Weisleder, N.2
  • 19
    • 84862907349 scopus 로고    scopus 로고
    • Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy
    • Weisleder N, Takizawa N, Lin P, et al. Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy. Sci Transl Med 2012; 4:1-11.
    • (2012) Sci Transl Med , vol.4 , pp. 1-11
    • Weisleder, N.1    Takizawa, N.2    Lin, P.3
  • 20
    • 79955867741 scopus 로고    scopus 로고
    • Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse
    • Tinsley JM, Fairclough RJ, Storer R, et al. Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse. PLoS One 2011; 6:e19189.
    • (2011) PLoS One , vol.6
    • Tinsley, J.M.1    Fairclough, R.J.2    Storer, R.3
  • 21
    • 79551667507 scopus 로고    scopus 로고
    • Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice
    • Amenta AR, Yilmaz A, Bogdanovich S, et al. Biglycan recruits utrophin to the sarcolemma and counters dystrophic pathology in mdx mice. Proc Natl Acad Sci U S A 2011; 108:762-767.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 762-767
    • Amenta, A.R.1    Yilmaz, A.2    Bogdanovich, S.3
  • 22
    • 84865579177 scopus 로고    scopus 로고
    • Biglycan: A promising new therapeutic for neuromuscular and musculoskeletal diseases
    • Young MF, Fallon Jr. Biglycan: A promising new therapeutic for neuromuscular and musculoskeletal diseases. Curr Opin Genet Dev 2012; 22:398-400.
    • (2012) Curr Opin Genet Dev , vol.22 , pp. 398-400
    • Young, M.F.1    Fallon, J.R.2
  • 23
    • 84861702194 scopus 로고    scopus 로고
    • The Canadian experience with long-term deflazacort treatment in Duchenne muscular dystrophy
    • McAdam LC, Mayo AL, Alman BA, Biggar WD. The Canadian experience with long-term deflazacort treatment in Duchenne muscular dystrophy. Acta Myol 2012; 31:16-20.
    • (2012) Acta Myol , vol.31 , pp. 16-20
    • McAdam, L.C.1    Mayo, A.L.2    Alman, B.A.3    Biggar, W.D.4
  • 24
    • 84879551364 scopus 로고    scopus 로고
    • Corticosteroids in Duchenne muscular dystrophy: Major variations in practice
    • Griggs RC, Herr BE, Reha A, et al. Corticosteroids in Duchenne muscular dystrophy: Major variations in practice. Muscle Nerve 2013; 48:27-31.
    • (2013) Muscle Nerve , vol.48 , pp. 27-31
    • Griggs, R.C.1    Herr, B.E.2    Reha, A.3
  • 25
    • 84877594408 scopus 로고    scopus 로고
    • Long-term benefits and adverse effects of intermittent versus daily glucocorticoids in boys with Duchenne muscular dystrophy
    • Ricotti V, Ridout DA, Scott E, et al. Long-term benefits and adverse effects of intermittent versus daily glucocorticoids in boys with Duchenne muscular dystrophy. J Neurol Neurosurg Psychiatry 2013; 84:698-705.
    • (2013) J Neurol Neurosurg Psychiatry , vol.84 , pp. 698-705
    • Ricotti, V.1    Ridout, D.A.2    Scott, E.3
  • 26
    • 84866327595 scopus 로고    scopus 로고
    • Delta-9,11 modification of glucocorticoids dissociates nuclear factor-kappa B inhibitory efficacy from glucocorticoid response element-associated side effects
    • Baudy AR, Reeves EK, Damsker JM, et al. Delta-9,11 modification of glucocorticoids dissociates nuclear factor-kappa B inhibitory efficacy from glucocorticoid response element-associated side effects. J Pharmacol Exp Ther 2012; 343:225-232.
    • (2012) J Pharmacol Exp Ther , vol.343 , pp. 225-232
    • Baudy, A.R.1    Reeves, E.K.2    Damsker, J.M.3
  • 27
    • 84875738549 scopus 로고    scopus 로고
    • VBP15: Preclinical characterization of a novel anti-inflammatory delta 9,11 steroid
    • Reeves EK, Hoffman EP, Nagaraju K, et al. VBP15: Preclinical characterization of a novel anti-inflammatory delta 9,11 steroid. Bioorg Med Chem 2013; 21:2241-2249.
    • (2013) Bioorg Med Chem , vol.21 , pp. 2241-2249
    • Reeves, E.K.1    Hoffman, E.P.2    Nagaraju, K.3
  • 28
    • 84872677715 scopus 로고    scopus 로고
    • The anticancer drug tamoxifen counteracts the pathology in a mouse model of Duchenne muscular dystrophy
    • Dorchies OM, Reutenauer-Patte J, Dahmane E, et al. The anticancer drug tamoxifen counteracts the pathology in a mouse model of Duchenne muscular dystrophy. Am J Pathol 2013; 182:485-504.
    • (2013) Am J Pathol , vol.182 , pp. 485-504
    • Dorchies, O.M.1    Reutenauer-Patte, J.2    Dahmane, E.3
  • 29
    • 84867369654 scopus 로고    scopus 로고
    • Identification of a 4-hydroxymethyl diarylhydantoin as a selective androgen receptor modulator
    • Nique F, Hebbe S, Triballeau N, et al. Identification of a 4-hydroxymethyl diarylhydantoin as a selective androgen receptor modulator. J Med Chem 2012; 55:8236-8247.
    • (2012) J Med Chem , vol.55 , pp. 8236-8247
    • Nique, F.1    Hebbe, S.2    Triballeau, N.3
  • 30
    • 84876994641 scopus 로고    scopus 로고
    • GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy
    • Cozzoli A, Capogrosso RF, Sblendorio VT, et al. GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy. Pharmacol Res 2013; 72:9-24.
    • (2013) Pharmacol Res , vol.72 , pp. 9-24
    • Cozzoli, A.1    Capogrosso, R.F.2    Sblendorio, V.T.3
  • 31
    • 84859158181 scopus 로고    scopus 로고
    • Therapeutic potential of pegylated insulin-like growth factor 1 for skeletal muscle disease evaluated in two murine models of muscular dystrophy
    • Gehrig SM, van der Poel C, Hoeflich A, et al. Therapeutic potential of pegylated insulin-like growth factor 1 for skeletal muscle disease evaluated in two murine models of muscular dystrophy. Growth Horm IGF Res 2012; 22:69-75.
    • (2012) Growth Horm IGF Res , vol.22 , pp. 69-75
    • Gehrig, S.M.1    Van Der Poel, C.2    Hoeflich, A.3
  • 32
    • 84883778679 scopus 로고    scopus 로고
    • New modulators for IGF-1 activity within IGF-1 processing products
    • Brisson BK, Barton ER. New modulators for IGF-1 activity within IGF-1 processing products. Front Endocrinol 2013; 42:1-6.
    • (2013) Front Endocrinol , vol.42 , pp. 1-6
    • Brisson, B.K.1    Barton, E.R.2
  • 33
    • 84855999113 scopus 로고    scopus 로고
    • Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and EPAC-dependent pathways
    • Reutenauer-Patte J, Boittin JF, Patthey-Vuadens O, et al. Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and EPAC-dependent pathways. Am J Pathol 2012; 180:749-762.
    • (2012) Am J Pathol , vol.180 , pp. 749-762
    • Reutenauer-Patte, J.1    Boittin, J.F.2    Patthey-Vuadens, O.3
  • 34
    • 84864773923 scopus 로고    scopus 로고
    • Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy
    • Percival JM, Whitehead NP, Adams ME, et al. Sildenafil reduces respiratory muscle weakness and fibrosis in the mdx mouse model of Duchenne muscular dystrophy. J Pathol 2012; 228:77-87.
    • (2012) J Pathol , vol.228 , pp. 77-87
    • Percival, J.M.1    Whitehead, N.P.2    Adams, M.E.3
  • 35
    • 84862609545 scopus 로고    scopus 로고
    • Interference with myostatin/ActRIIB signaling as a therapeutic strategy for Duchenne muscular dystrophy
    • Amthor H, Hoogaars WM. Interference with myostatin/ActRIIB signaling as a therapeutic strategy for Duchenne muscular dystrophy. Curr Gene Ther 2012; 12:245-259.
    • (2012) Curr Gene Ther , vol.12 , pp. 245-259
    • Amthor, H.1    Hoogaars, W.M.2
  • 37
    • 84885174406 scopus 로고    scopus 로고
    • Myostatin/activin pathway antagonism: Molecular basis and therapeutic potential
    • Epub ahead of print]
    • Han HQ, Zhou X, Mitch WE, Goldberg AL. Myostatin/activin pathway antagonism: Molecular basis and therapeutic potential. Int J Biochem Cell Biol 2013. [Epub ahead of print]
    • (2013) Int J Biochem Cell Biol
    • Han, H.Q.1    Zhou, X.2    Mitch, W.E.3    Goldberg, A.L.4
  • 39
    • 84869821048 scopus 로고    scopus 로고
    • Orai1 mediates exacerbated calcium entry in dystrophic skeletal muscle
    • Zhao X, Moloughney JG, Zhang S, et al. Orai1 mediates exacerbated calcium entry in dystrophic skeletal muscle. PLoS One 2012; 7:e49862.
    • (2012) PLoS One , vol.7
    • Zhao, X.1    Moloughney, J.G.2    Zhang, S.3
  • 40
    • 84862277020 scopus 로고    scopus 로고
    • TRP channels in normal and dystrophic skeletal muscle
    • Gailly P. TRP channels in normal and dystrophic skeletal muscle. Curr Opin Pharmacol 2012; 12:326-334.
    • (2012) Curr Opin Pharmacol , vol.12 , pp. 326-334
    • Gailly, P.1
  • 41
    • 84878667441 scopus 로고    scopus 로고
    • Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of alpha1-syntrophin and PLC/PKC in SOCE regulation
    • Harisseh R, Chatelier A, Magaud C, et al. Involvement of TRPV2 and SOCE in calcium influx disorder in DMD primary human myotubes with a specific contribution of alpha1-syntrophin and PLC/PKC in SOCE regulation. Am J Physiol Cell Physiol 2013; 304:C881-C894.
    • (2013) Am J Physiol Cell Physiol , vol.304
    • Harisseh, R.1    Chatelier, A.2    Magaud, C.3
  • 42
    • 84930607375 scopus 로고    scopus 로고
    • Store-operated channels and calcium handling in muscular dystrophy
    • Groschner K, Graier WF, Romanin C, editors. . Vienna Springer
    • Ruegg UT, Shapovalov G, Jacobson KV, et al. Store-operated channels and calcium handling in muscular dystrophy. In: Groschner K, Graier WF, Romanin C, editors. Store-operated calcium entry (SOCE) pathways. Vienna: Springer; 2012. pp. 449-457.
    • (2012) Store-operated calcium entry (SOCE) pathways , pp. 449-457
    • Ruegg, U.T.1    Shapovalov, G.2    Jacobson, K.V.3
  • 43
    • 84872055469 scopus 로고    scopus 로고
    • Activation of calcium signaling through TRPV1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy
    • Ito N, Ruegg UT, Kudo A, et al. Activation of calcium signaling through TRPV1 by nNOS and peroxynitrite as a key trigger of skeletal muscle hypertrophy. Nat Med 2013; 19:101-106.
    • (2013) Nat Med , vol.19 , pp. 101-106
    • Ito, N.1    Ruegg, U.T.2    Kudo, A.3
  • 44
    • 84876304597 scopus 로고    scopus 로고
    • Dysfunctional ryanodine receptors in the heart: New insights into complex cardiovascular diseases
    • Marx SO, Marks AR. Dysfunctional ryanodine receptors in the heart: New insights into complex cardiovascular diseases. J Mol Cell Cardiol 2013; 58:225-231.
    • (2013) J Mol Cell Cardiol , vol.58 , pp. 225-231
    • Marx, S.O.1    Marks, A.R.2
  • 45
    • 84874753450 scopus 로고    scopus 로고
    • Leaky ryanodine receptors in betasarcoglycan deficient mice: A potential common defect in muscular dystrophy
    • Andersson DC, Meli AC, Reiken S, et al. Leaky ryanodine receptors in betasarcoglycan deficient mice: A potential common defect in muscular dystrophy. Skelet Muscle 2012; 2:2-9.
    • (2012) Skelet Muscle , vol.2 , pp. 2-9
    • Andersson, D.C.1    Meli, A.C.2    Reiken, S.3
  • 46
    • 84883251517 scopus 로고    scopus 로고
    • Blockade of sarcolemmal TRPV2 accumulation inhibits progression of dilated cardiomyopathy
    • Epub ahead of print]
    • Iwata Y, Ohtake H, Suzuki O, et al. Blockade of sarcolemmal TRPV2 accumulation inhibits progression of dilated cardiomyopathy. Cardiovasc Res 2013. [Epub ahead of print]
    • (2013) Cardiovasc Res
    • Iwata, Y.1    Ohtake, H.2    Suzuki, O.3
  • 47
    • 84878250751 scopus 로고    scopus 로고
    • Capsaicin mimics mechanical load-induced intracellular signaling events: Involvement of TRPV1-mediated calcium signaling in induction of skeletal muscle hypertrophy
    • Ito N, Ruegg UT, Kudo A, et al. Capsaicin mimics mechanical load-induced intracellular signaling events: Involvement of TRPV1-mediated calcium signaling in induction of skeletal muscle hypertrophy. Channels 2013; 7:221-224.
    • (2013) Channels , vol.7 , pp. 221-224
    • Ito, N.1    Ruegg, U.T.2    Kudo, A.3
  • 49
    • 84876031864 scopus 로고    scopus 로고
    • Dimers of mitochondrial ATP synthase form the permeability transition pore
    • Giorgio V, von Stockum S, Antoniel M, et al. Dimers of mitochondrial ATP synthase form the permeability transition pore. Proc Natl Acad Sci U S A 2013; 110:5887-5892.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 5887-5892
    • Giorgio, V.1    Von Stockum, S.2    Antoniel, M.3
  • 50
    • 53849097675 scopus 로고    scopus 로고
    • Investigation of Debio-025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy
    • Reutenauer J, Dorchies OM, Patthey-Vuadens O, et al. Investigation of Debio-025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy. Br J Pharmacol 2008; 155:574-584.
    • (2008) Br J Pharmacol , vol.155 , pp. 574-584
    • Reutenauer, J.1    Dorchies, O.M.2    Patthey-Vuadens, O.3
  • 51
    • 77957752614 scopus 로고    scopus 로고
    • Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice
    • Wissing ER, Millay DP, Vuagniaux G, et al. Debio-025 is more effective than prednisone in reducing muscular pathology in mdx mice. Neuromuscul Disord 2010; 20:753-760.
    • (2010) Neuromuscul Disord , vol.20 , pp. 753-760
    • Wissing, E.R.1    Millay, D.P.2    Vuagniaux, G.3
  • 52
    • 77957952187 scopus 로고    scopus 로고
    • Treatment of Duchenne muscular dystrophy with ciclosporin A: A randomised, double-blind, placebo-controlled multicentre trial
    • Kirschner J, Schessl J, Schara U, et al. Treatment of Duchenne muscular dystrophy with ciclosporin A: A randomised, double-blind, placebo-controlled multicentre trial. Lancet Neurol 2010; 9:1053-1059.
    • (2010) Lancet Neurol , vol.9 , pp. 1053-1059
    • Kirschner, J.1    Schessl, J.2    Schara, U.3
  • 53
    • 84867920817 scopus 로고    scopus 로고
    • Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model
    • Jahnke VE, Van Der Meulen JH, Johnston HK, et al. Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model. Skelet Muscle 2012; 2:16.
    • (2012) Skelet Muscle , vol.2 , pp. 16
    • Jahnke, V.E.1    Van Der Meulen, J.H.2    Johnston, H.K.3
  • 54
    • 84859910158 scopus 로고    scopus 로고
    • HSP72 preserves muscle function and slows progression of severe muscular dystrophy
    • Gehrig SM, van der Poel C, Sayer TA, et al. HSP72 preserves muscle function and slows progression of severe muscular dystrophy. Nature 2012; 484: 394-398.
    • (2012) Nature , vol.484 , pp. 394-398
    • Gehrig, S.M.1    Van Der Poel, C.2    Sayer, T.A.3
  • 55
    • 84876312106 scopus 로고    scopus 로고
    • Cardiac phenotype of Duchenne muscular dystrophy: Insights from cellular studies
    • Shirokova N, Niggli E. Cardiac phenotype of Duchenne muscular dystrophy: Insights from cellular studies. J Mol Cell Cardiol 2013; 58:217-224.
    • (2013) J Mol Cell Cardiol , vol.58 , pp. 217-224
    • Shirokova, N.1    Niggli, E.2
  • 56
    • 84883789227 scopus 로고    scopus 로고
    • Diapocynin inhibits ROS production and prevents force loss in eccentrically contracting dystrophic muscle
    • in press)
    • Ismail HM, Ruegg UT, Dorchies OM, et al. Diapocynin inhibits ROS production and prevents force loss in eccentrically contracting dystrophic muscle. PLoS One (in press).
    • PLoS One
    • Ismail, H.M.1    Ruegg, U.T.2    Dorchies, O.M.3
  • 57
    • 84872858018 scopus 로고    scopus 로고
    • Contribution of oxidative stress to pathology in diaphragm and limb muscles with Duchenne muscular dystrophy
    • Kim JH, Kwak HB, Thompson LV. Contribution of oxidative stress to pathology in diaphragm and limb muscles with Duchenne muscular dystrophy. J Muscle Res Cell Motil 2013; 34:1-13.
    • (2013) J Muscle Res Cell Motil , vol.34 , pp. 1-13
    • Kim, J.H.1    Kwak, H.B.2    Thompson, L.V.3
  • 58
    • 84859627102 scopus 로고    scopus 로고
    • N-acetylcysteine treatment of dystrophic mdx mice results in protein thiol modifications and inhibition of exercise induced myofibre necrosis
    • Terrill JR, Radley-Crabb HG, Grounds MD, Arthur PG. N-acetylcysteine treatment of dystrophic mdx mice results in protein thiol modifications and inhibition of exercise induced myofibre necrosis. Neuromuscul Disord 2012; 22:427-434.
    • (2012) Neuromuscul Disord , vol.22 , pp. 427-434
    • Terrill, J.R.1    Radley-Crabb, H.G.2    Grounds, M.D.3    Arthur, P.G.4
  • 59
    • 84865132471 scopus 로고    scopus 로고
    • Quantitative evaluation of the beneficial effects in the mdx mouse of epigallocatechin gallate, an antioxidant polyphenol from green tea
    • Nakae Y, Dorchies O, Stoward P, et al. Quantitative evaluation of the beneficial effects in the mdx mouse of epigallocatechin gallate, an antioxidant polyphenol from green tea. Histochem Cell Biol 2012; 137:811-827.
    • (2012) Histochem Cell Biol , vol.137 , pp. 811-827
    • Nakae, Y.1    Dorchies, O.2    Stoward, P.3
  • 60
    • 84883757689 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate: A useful, effective and safe clinical approach for targeted prevention and individualised treatment of neurological diseases?
    • Mahler A, Mandel S, Lorenz M, et al. Epigallocatechin-3-gallate: A useful, effective and safe clinical approach for targeted prevention and individualised treatment of neurological diseases?. EPMA J 2013; 4:5.
    • (2013) EPMA J , vol.4 , pp. 5
    • Mahler, A.1    Mandel, S.2    Lorenz, M.3
  • 61
    • 84858993843 scopus 로고    scopus 로고
    • Amplification of proinflammatory phenotype, damage, and weakness by oxidative stress in the diaphragm muscle of mdx mice
    • Kim JH, Lawler JM. Amplification of proinflammatory phenotype, damage, and weakness by oxidative stress in the diaphragm muscle of mdx mice. Free Radic Biol Med 2012; 52:1597-1606.
    • (2012) Free Radic Biol Med , vol.52 , pp. 1597-1606
    • Kim, J.H.1    Lawler, J.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.