N-Acetylcysteine treatment of dystrophic mdx mice results in protein thiol modifications and inhibition of exercise induced myofibre necrosis

Neuromuscular Disorders

Volumn 22, Issue 5, 2012, Pages 427-434

  Terrill, Jessica R ^a   Radley Crabb, Hannah G ^a   Grounds, Miranda D ^a   Arthur, Peter G ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Duchenne Muscular Dystrophy; Mdx Mouse; N Acetylcysteine; Oxidative stress; Protein thiol oxidation; Treadmill exercise

Indexed keywords

ACETYLCYSTEINE; CREATINE KINASE; DRINKING WATER; GLUTATHIONE; MALONALDEHYDE; MUSCLE PROTEIN; THIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DISEASE CONTROL; DRUG EFFICACY; DRUG MEGADOSE; ENZYME METABOLISM; EXERCISE; HISTOLOGY; IN VIVO STUDY; MALE; MOUSE; MUSCLE NECROSIS; MUSCULAR DYSTROPHY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CARBONYLATION; PROTEIN CONTENT; PROTEIN MODIFICATION; SARCOLEMMA; TREATMENT DURATION;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; GLUTATHIONE; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MUSCLE, SKELETAL; MUSCULAR DYSTROPHY, ANIMAL; NECROSIS; OXIDATIVE STRESS; PHYSICAL CONDITIONING, ANIMAL; PROTEIN CARBONYLATION; PROTEINS; SULFHYDRYL COMPOUNDS;

EID: 84859627102     PISSN: 09608966     EISSN: 18732364     Source Type: Journal    
DOI: 10.1016/j.nmd.2011.11.007     Document Type: Article

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