Reducing FLI1 Levels in the MRL/lpr Lupus Mouse Model Impacts T Cell Function by Modulating Glycosphingolipid Metabolism

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Richard, Erin Morris ^a,d   Thiyagarajan, Thirumagal ^a   Bunni, Marlene A ^a   Basher, Fahmin ^a   Roddy, Patrick O ^b   Siskind, Leah J ^b,c,e   Nietert, Paul J ^a   Nowling, Tamara K ^a,c  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^d Department of Teacher Education and Department of Sociology and Anthropology   (United States)

^e University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOSPHINGOLIPID; IMMUNOGLOBULIN; INTERLEUKIN 4; NEURAMINIDASE 1; SIALIDASE; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FLI 1; UNCLASSIFIED DRUG; FLI1 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; RAG-1 PROTEIN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; EX VIVO STUDY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; LIPID METABOLISM; MOUSE; NEU1 GENE; NONHUMAN; PROMOTER REGION; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE; ANIMAL; BIOSYNTHESIS; DEFICIENCY; DISEASE MODEL; IMMUNOLOGY; JURKAT CELL LINE; LYMPHOCYTE ACTIVATION; METABOLISM; MURPHY ROTHS LARGE LYMPHOPROLIFERATIVE MOUSE;

ADOPTIVE TRANSFER; ANIMALS; B-LYMPHOCYTES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; GLYCOSPHINGOLIPIDS; HOMEODOMAIN PROTEINS; HUMANS; INTERLEUKIN-4; JURKAT CELLS; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED MRL LPR; PROTO-ONCOGENE PROTEIN C-FLI-1; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES;

EID: 84883759952     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0075175     Document Type: Article

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