메뉴 건너뛰기




Volumn 39, Issue 3, 2010, Pages 332-339

Loss of 15-hydroxyprostaglandin dehydrogenase increases prostaglandin E2 in pancreatic tumors

Author keywords

15 hydroxyprostaglandin dehydrogenase; Cyclooxygenase 2; Microsomal prostaglandin E synthase; Prostaglandin E2; SNAI2

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; CARRIER PROTEIN; CYCLOOXYGENASE 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; PROSTAGLANDIN E SYNTHASE 1; PROSTAGLANDIN E2; SNAIL HOMOLOG 1 PROTEIN; TRANSCRIPTION FACTOR SLUG; UNCLASSIFIED DRUG;

EID: 77950237476     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPA.0b013e3181baecbe     Document Type: Article
Times cited : (20)

References (45)
  • 2
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandin and cancer
    • Wang D, Dubois RN. Prostaglandin and cancer. Gut. 2006;55:115-122.
    • (2006) Gut , vol.55 , pp. 115-122
    • Wang, D.1    Dubois, R.N.2
  • 4
    • 0038489501 scopus 로고    scopus 로고
    • Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer
    • Chu J, Lloyd FL, Trifan OC, et al. Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer. Mol Cancer Ther. 2003;2:1-7.
    • (2003) Mol Cancer Ther , vol.2 , pp. 1-7
    • Chu, J.1    Lloyd, F.L.2    Trifan, O.C.3
  • 5
    • 0037757694 scopus 로고    scopus 로고
    • PGE2 is generated by specific COX-2 activity and increases VEGF production in COX-2-expressing human pancreatic cancer cells
    • Eibl G, Bruemmer D, Okada Y, et al. PGE2 is generated by specific COX-2 activity and increases VEGF production in COX-2-expressing human pancreatic cancer cells. Biochem Biophys Res Commun. 2003;306(4):887-897.
    • (2003) Biochem Biophys Res Commun , vol.306 , Issue.4 , pp. 887-897
    • Eibl, G.1    Bruemmer, D.2    Okada, Y.3
  • 6
    • 0025810578 scopus 로고
    • A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP
    • Clark JD, Lin LL, Kriz RW, et al. A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP. Cell. 1991;65:1043-1051.
    • (1991) Cell , vol.65 , pp. 1043-1051
    • Clark, J.D.1    Lin, L.L.2    Kriz, R.W.3
  • 7
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochem. 2000;69:145-182.
    • (2000) Annu Rev Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    De Witt, D.L.2    Garavito, R.M.3
  • 8
    • 0242438644 scopus 로고    scopus 로고
    • Cyclooxygenase-2 modulates cellular growth and promotes tumorigenesis
    • Trifan OC, Hla T. Cyclooxygenase-2 modulates cellular growth and promotes tumorigenesis. J Cell Mol Med. 2003;7:207-222.
    • (2003) J Cell Mol Med , vol.7 , pp. 207-222
    • Trifan, O.C.1    Hla, T.2
  • 9
    • 0033963927 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression in human pancreatic adenocarcinomas
    • Yip-Schneider MT, Barnard DS, Billings SD, et al. Cyclooxygenase-2 expression in human pancreatic adenocarcinomas. Carcinogenesis. 2000;21:139-146.
    • (2000) Carcinogenesis , vol.21 , pp. 139-146
    • Yip-Schneider, M.T.1    Barnard, D.S.2    Billings, S.D.3
  • 10
    • 0034692689 scopus 로고    scopus 로고
    • Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2
    • Murakami M, Naraba H, Tanioka T, et al. Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2. J Biol Chem. 2000;275:32783-32792.
    • (2000) J Biol Chem , vol.275 , pp. 32783-32792
    • Murakami, M.1    Naraba, H.2    Tanioka, T.3
  • 11
    • 0033594963 scopus 로고    scopus 로고
    • Identification of human prostaglandin e synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target
    • Jakobsson PJ, Thoren S, Morgenstern R, et al. Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci USA. 1999;96:7220-7225.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 7220-7225
    • Jakobsson, P.J.1    Thoren, S.2    Morgenstern, R.3
  • 12
    • 0035830931 scopus 로고    scopus 로고
    • Cloning, expression, and up-regulation of inducible rat prostaglandin e synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis
    • Mancini JA, Blood K, Guay J, et al. Cloning, expression, and up-regulation of inducible rat prostaglandin E synthase during lipopolysaccharide-induced pyresis and adjuvant-induced arthritis. J Biol Chem. 2001;267:4469-4475.
    • (2001) J Biol Chem , vol.267 , pp. 4469-4475
    • Mancini, J.A.1    Blood, K.2    Guay, J.3
  • 14
    • 0142155612 scopus 로고    scopus 로고
    • Cytokeratin 20, AN43, PGDH, and COX-2 expression in transitional and squamous cell carcinoma of the bladder
    • Gee JR, Montoya RG, Khaled HM, et al. Cytokeratin 20, AN43, PGDH, and COX-2 expression in transitional and squamous cell carcinoma of the bladder. Urol Oncol. 2003;21:266-270.
    • (2003) Urol Oncol , vol.21 , pp. 266-270
    • Gee, J.R.1    Montoya, R.G.2    Khaled, H.M.3
  • 15
    • 2042443068 scopus 로고    scopus 로고
    • Tumor growth inhibition by indomethacin in a mouse model of human medullary thyroid cancer: Implication of cyclooxygenases and 15-hydroxyprostaglandin dehydrogenase
    • Quidville V, Segond N, Pidoux E, et al. Tumor growth inhibition by indomethacin in a mouse model of human medullary thyroid cancer: implication of cyclooxygenases and 15-hydroxyprostaglandin dehydrogenase. Endocrinology. 2004;145:2561-2571.
    • (2004) Endocrinology , vol.145 , pp. 2561-2571
    • Quidville, V.1    Segond, N.2    Pidoux, E.3
  • 16
    • 13544268334 scopus 로고    scopus 로고
    • 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer
    • Backlund MG, Mann JR, Holla VR, et al. 15-Hydroxyprostaglandin dehydrogenase is down-regulated in colorectal cancer. J Biol Chem. 2005;280:3217-3223.
    • (2005) J Biol Chem , vol.280 , pp. 3217-3223
    • Backlund, M.G.1    Mann, J.R.2    Holla, V.R.3
  • 17
    • 0142258011 scopus 로고    scopus 로고
    • Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase
    • Cho H, Oliveira MA, Tai HH. Critical residues for the coenzyme specificity of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase. Arch Biochem Biophys. 2003;419:139-146.
    • (2003) Arch Biochem Biophys , vol.419 , pp. 139-146
    • Cho, H.1    Oliveira, M.A.2    Tai, H.H.3
  • 18
    • 33750443959 scopus 로고    scopus 로고
    • Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells
    • Tong M, Ding Y, Tai HH. Reciprocal regulation of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase expression in A549 human lung adenocarcinoma cells. Carcinogenesis. 2006;27: 2170-2179.
    • (2006) Carcinogenesis , vol.27 , pp. 2170-2179
    • Tong, M.1    Ding, Y.2    Tai, H.H.3
  • 19
    • 34250815766 scopus 로고    scopus 로고
    • Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer
    • Yang L, Amann JM, Kikuchi T, et al. Inhibition of epidermal growth factor receptor signaling elevates 15-hydroxyprostaglandin dehydrogenase in non-small-cell lung cancer. Cancer Res. 2007; 67:5587-5593.
    • (2007) Cancer Res , vol.67 , pp. 5587-5593
    • Yang, L.1    Amann, J.M.2    Kikuchi, T.3
  • 20
    • 0031587945 scopus 로고    scopus 로고
    • Characterization of the genomic structure and promoter of the mouse NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene
    • Matsuo M, Ensor CM, Tai HH. Characterization of the genomic structure and promoter of the mouse NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene. Biochem Biophys Res Commun. 1997;235:582-586.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 582-586
    • Matsuo, M.1    Ensor, C.M.2    Tai, H.H.3
  • 21
    • 0033197879 scopus 로고    scopus 로고
    • SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein
    • Inukai T, Inoue A, Kurosawa H, et al. SLUG, a ces-1-related zinc finger transcription factor gene with antiapoptotic activity, is a downstream target of the E2A-HLF oncoprotein. Mol Cell. 1999;4: 343-352.
    • (1999) Mol Cell , vol.4 , pp. 343-352
    • Inukai, T.1    Inoue, A.2    Kurosawa, H.3
  • 22
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of lipids from animal tissue
    • Folch J, Lees M, Stanley GHS. A simple method for the isolation and purification of lipids from animal tissue. J Biol Chem. 1957;226: 497-509.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Stanley, G.H.S.3
  • 23
    • 0345599013 scopus 로고    scopus 로고
    • Autoregulation of E-cadherin expression by cadherin-cadherin interactions: The roles of beta-catenin signaling, Slug and MAPK
    • Conacci-Sorrell M, Simcha I, Ben-Yedidia T, et al. Autoregulation of E-cadherin expression by cadherin-cadherin interactions: the roles of beta-catenin signaling, Slug and MAPK. J Cell Biol. 2003;163: 847-857.
    • (2003) J Cell Biol , vol.163 , pp. 847-857
    • Conacci-Sorrell, M.1    Simcha, I.2    Ben-Yedidia, T.3
  • 24
    • 33744925683 scopus 로고    scopus 로고
    • Cyclooxygenase-2-dependent regulation of E-cadherin: Prostaglandin E2 induces transcriptional repressors ZEB1 and Snail in non-small cell lung cancer
    • Dohadwala M, Yang SC, Luo J, et al. Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E2 induces transcriptional repressors ZEB1 and Snail in non-small cell lung cancer. Cancer Res. 2006;66:5338-5345.
    • (2006) Cancer Res , vol.66 , pp. 5338-5345
    • Dohadwala, M.1    Yang, S.C.2    Luo, J.3
  • 25
    • 33746173092 scopus 로고    scopus 로고
    • Repression of prostaglandin dehydrogenase by epidermal growth factor and Snail increases prostaglandin E2 and promotes cancer progression
    • Mann JR, Backlund MG, Buchanan FG, et al. Repression of prostaglandin dehydrogenase by epidermal growth factor and Snail increases prostaglandin E2 and promotes cancer progression. Cancer Res. 2006;66:6649-6656.
    • (2006) Cancer Res , vol.66 , pp. 6649-6656
    • Mann, J.R.1    Backlund, M.G.2    Buchanan, F.G.3
  • 26
    • 55949098253 scopus 로고    scopus 로고
    • Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers
    • Hasan S, Satake M, Dawson DW, et al. Expression analysis of the prostaglandin E2 production pathway in human pancreatic cancers. Pancreas. 2008;37:121-127.
    • (2008) Pancreas , vol.37 , pp. 121-127
    • Hasan, S.1    Satake, M.2    Dawson, D.W.3
  • 27
    • 0033106051 scopus 로고    scopus 로고
    • Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer
    • Tucker ON, Dannenberg AJ, Yang EK, et al. Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer. Cancer Res. 1999;59:987-990.
    • (1999) Cancer Res , vol.59 , pp. 987-990
    • Tucker, O.N.1    Dannenberg, A.J.2    Yang, E.K.3
  • 28
    • 6544295983 scopus 로고    scopus 로고
    • Overexpression of cyclooxygenase-2 in carcinoma of the pancreas
    • Okami J, Yamamoto H, Fujiwara Y, et al. Overexpression of cyclooxygenase-2 in carcinoma of the pancreas. Clin Cancer Res. 1999;5:2018-2024.
    • (1999) Clin Cancer Res , vol.5 , pp. 2018-2024
    • Okami, J.1    Yamamoto, H.2    Fujiwara, Y.3
  • 29
    • 0033199017 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: Growth inhibition by nonsteroidal anti-inflammatory drugs
    • Molina MA, Sitja-Arnau M, Lemoine MG, et al. Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs. Cancer Res. 1999;59:4356-4362.
    • (1999) Cancer Res , vol.59 , pp. 4356-4362
    • Molina, M.A.1    Sitja-Arnau, M.2    Lemoine, M.G.3
  • 30
    • 31544467315 scopus 로고    scopus 로고
    • A phase II study of celecoxib, gemcitabine, and cisplatin in advanced pancreatic cancer
    • El-Rayes BF, Zalupski MM, Shields AF, et al. A phase II study of celecoxib, gemcitabine, and cisplatin in advanced pancreatic cancer. Invest New Drugs. 2005;23:583-590.
    • (2005) Invest New Drugs , vol.23 , pp. 583-590
    • El-Rayes, B.F.1    Zalupski, M.M.2    Shields, A.F.3
  • 31
    • 28844482332 scopus 로고    scopus 로고
    • Gemcitabine plus celecoxib (GECO) in advanced pancreatic cancer: A phase II trial
    • Ferrari V, Valcamonico F, Amoroso V, et al. Gemcitabine plus celecoxib (GECO) in advanced pancreatic cancer: a phase II trial. Cancer Chemother Pharmacol. 2006;57:185-190.
    • (2006) Cancer Chemother Pharmacol , vol.57 , pp. 185-190
    • Ferrari, V.1    Valcamonico, F.2    Amoroso, V.3
  • 32
    • 42049123958 scopus 로고    scopus 로고
    • Gemcitabine plus celecoxib in patients with advanced or metastatic pancreatic adenocarcinoma: Results of a phase II trial
    • Dragovich T, Burris H 3rd, Loehrer P, et al. Gemcitabine plus celecoxib in patients with advanced or metastatic pancreatic adenocarcinoma: results of a phase II trial. Am J Clin Oncol. 2008; 31:157-162.
    • (2008) Am J Clin Oncol , vol.31 , pp. 157-162
    • Dragovich, T.1    Burris III, H.2    Loehrer, P.3
  • 33
    • 0028300145 scopus 로고
    • Effects of dietary linoleic acid on pancreatic carcinogenesis in rats and hamsters
    • Appel MJ, van Garderen-Hoetmer A, Woutersen RA. Effects of dietary linoleic acid on pancreatic carcinogenesis in rats and hamsters. Cancer Res. 1994;54:2113-2120.
    • (1994) Cancer Res , vol.54 , pp. 2113-2120
    • Appel, M.J.1    Van Garderen-Hoetmer, A.2    Woutersen, R.A.3
  • 34
    • 41649094069 scopus 로고    scopus 로고
    • Tumor COX-2 expression and prognosis of patients with resectable pancreatic cancer
    • Matsubayashi H, Infante JR, Winter J, et al. Tumor COX-2 expression and prognosis of patients with resectable pancreatic cancer. Cancer Biol Ther. 2007;6:1569-1575.
    • (2007) Cancer Biol Ther , vol.6 , pp. 1569-1575
    • Matsubayashi, H.1    Infante, J.R.2    Winter, J.3
  • 35
    • 52749094806 scopus 로고    scopus 로고
    • Expression of COX-2 is associated with accumulation of p53 in pancreatic cancer: Analysis of COX-2 and p53 expression in premalignant and malignant ductal pancreatic lesions
    • Hermanova M, Trna J, Nenutil R, et al. Expression of COX-2 is associated with accumulation of p53 in pancreatic cancer: analysis of COX-2 and p53 expression in premalignant and malignant ductal pancreatic lesions. Eur J Gastroenterol Hepatol. 2008;20:732-739.
    • (2008) Eur J Gastroenterol Hepatol , vol.20 , pp. 732-739
    • Hermanova, M.1    Trna, J.2    Nenutil, R.3
  • 36
    • 60749086869 scopus 로고    scopus 로고
    • Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: Novel chemotherapeutic targets in pancreatic endocrine tumors?
    • Bergmann F, Breinig M, Höpfner M, et al. Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: novel chemotherapeutic targets in pancreatic endocrine tumors? Am J Gastroenterol. 2009;104:171-181.
    • (2009) Am J Gastroenterol , vol.104 , pp. 171-181
    • Bergmann, F.1    Breinig, M.2    Höpfner, M.3
  • 37
    • 0036594073 scopus 로고    scopus 로고
    • Prostaglandin receptors: Advances in the study of EP3 receptor signaling
    • Hatae N, Sugimoto Y, Ichikawa A. Prostaglandin receptors: advances in the study of EP3 receptor signaling. J Biochem. 2002;131:781-784.
    • (2002) J Biochem , vol.131 , pp. 781-784
    • Hatae, N.1    Sugimoto, Y.2    Ichikawa, A.3
  • 38
    • 0242321274 scopus 로고    scopus 로고
    • EP2 and EP4 prostanoid receptor signaling
    • Regan JW. EP2 and EP4 prostanoid receptor signaling. Life Sci. 2003;74:143-153.
    • (2003) Life Sci , vol.74 , pp. 143-153
    • Regan, J.W.1
  • 39
    • 34249729416 scopus 로고    scopus 로고
    • Prostaglandin e receptors
    • Sugimoto Y, Narumiya S. Prostaglandin E receptors. J Biol Chem. 2007;282:11613-11617.
    • (2007) J Biol Chem , vol.282 , pp. 11613-11617
    • Sugimoto, Y.1    Narumiya, S.2
  • 40
    • 12544256290 scopus 로고    scopus 로고
    • Angiotensin II and epidermal growth factor induce cyclooxygenase-2 expression in intestinal epithelial cells through small GTPases using distinct signaling pathways
    • Slice LW, Chiu T, Rozengurt E. Angiotensin II and epidermal growth factor induce cyclooxygenase-2 expression in intestinal epithelial cells through small GTPases using distinct signaling pathways. J Biol Chem. 2005;280:1582-1593.
    • (2005) J Biol Chem , vol.280 , pp. 1582-1593
    • Slice, L.W.1    Chiu, T.2    Rozengurt, E.3
  • 41
    • 33746551585 scopus 로고    scopus 로고
    • CREB-dependent cyclooxygenase-2 and microsomal prostaglandin e synthase-1 expression is mediated by protein kinase C and calcium
    • Pham H, Shafer LM, Slice LW. CREB-dependent cyclooxygenase-2 and microsomal prostaglandin E synthase-1 expression is mediated by protein kinase C and calcium. J Cell Biochem. 2006;98:1653-1666.
    • (2006) J Cell Biochem , vol.98 , pp. 1653-1666
    • Pham, H.1    Shafer, L.M.2    Slice, L.W.3
  • 42
    • 36849036396 scopus 로고    scopus 로고
    • Ang II and EGF synergistically induce COX-2 expression via CREB in intestinal epithelial cells
    • Pham H, Chong B, Vincenti R, et al. Ang II and EGF synergistically induce COX-2 expression via CREB in intestinal epithelial cells. J Cell Physiol. 2008;214:96-109.
    • (2008) J Cell Physiol , vol.214 , pp. 96-109
    • Pham, H.1    Chong, B.2    Vincenti, R.3
  • 43
    • 0032567649 scopus 로고    scopus 로고
    • Dissociation of basal turnover and cytokine-induced transcript stabilization of the human cyclooxygenase-2 mRNA by mutagenesis of the 3¶-untranslated region
    • Gou Q, Liu CH, Ben-Av P, et al. Dissociation of basal turnover and cytokine-induced transcript stabilization of the human cyclooxygenase-2 mRNA by mutagenesis of the 3¶-untranslated region. Biochem Biophys Res Commun. 1998;242:508-512.
    • (1998) Biochem Biophys Res Commun , vol.242 , pp. 508-512
    • Gou, Q.1    Liu, C.H.2    Ben-Av, P.3
  • 44
    • 0034697027 scopus 로고    scopus 로고
    • Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3¶-untranslated region
    • Dixon DA, Kaplan CD, McIntyre TM, et al. Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3¶-untranslated region. J Biol Chem. 2000;275:11750-11757.
    • (2000) J Biol Chem , vol.275 , pp. 11750-11757
    • Dixon, D.A.1    Kaplan, C.D.2    McIntyre, T.M.3
  • 45
    • 33750993498 scopus 로고    scopus 로고
    • Beta-Catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3¶-UTR
    • Lee HK, Jeong S. Beta-Catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3¶-UTR. Nucleic Acids Res. 2006;34:5705-5714.
    • (2006) Nucleic Acids Res , vol.34 , pp. 5705-5714
    • Lee, H.K.1    Jeong, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.