A common single-nucleotide polymorphism in cyclooxygenase-2 disrupts microRNA-mediated regulation

Oncogene

Volumn 31, Issue 12, 2012, Pages 1592-1598

  Moore, A E ^a   Young, L E ^a   Dixon, D A ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

COX 2; microRNA; polymorphism; post transcriptional regulation; SNP

Indexed keywords

CYCLOOXYGENASE 2; MICRORNA; TUMOR MARKER;

ALLELE; ARTICLE; BINDING SITE; CANCER CELL; CANCER PATIENT; CANCER TISSUE; COLON CANCER; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME DEGRADATION; ENZYME INHIBITION; GENE DOSAGE; GENE MUTATION; GENETIC ASSOCIATION; GENETIC REGULATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA BINDING; RNA TRANSCRIPTION; SINGLE NUCLEOTIDE POLYMORPHISM;

COLONIC NEOPLASMS; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION; HUMANS; MICRORNAS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84858865662     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.349     Document Type: Article

References (27)

1. Abdelmohsen K, Srikantan S, Kuwano Y, Gorospe M. (2008). miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels. Proc Natl Acad Sci USA 105: 20297-20302.
2. Ali IU, Luke BT, Dean M, Greenwald P. (2005). Allellic variants in regulatory regions of cyclooxygenase-2: association with advanced colorectal adenoma. Br J Cancer 93: 953-959. (Pubitemid 41487024)
3. Bhattacharyya SN, Habermacher R, Martine U, Closs EI, Filipowicz W. (2006). Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell 125: 1111-1124. (Pubitemid 43866197)
4. Birkenkamp-Demtroder K, Olesen SH, Sorensen FB, Laurberg S, Laiho P, Aaltonen LA et al. (2005). Differential gene expression in colon cancer of the caecum versus the sigmoid and rectosigmoid. Gut 54: 374-384. (Pubitemid 40299094)
5. Campa D, Zienolddiny S, Maggini V, Skaug V, Haugen A, Canzian F. (2004). Association of a common polymorphism in the cyclooxygenase 2 gene with risk of non-small cell lung cancer. Carcinogenesis 25: 229-235. (Pubitemid 38239806)
6. Croce CM. (2009). Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet 10: 704-714.
7. Dimberg J, Samuelsson A, Hugander A, Soderkvist P. (1999). Differential expression of cyclooxygenase 2 in human colorectal cancer. Gut 45: 730-732. (Pubitemid 29492147)
8. Dixon DA, Kaplan CD, McIntyre TM, Zimmerman GA, Prescott SM. (2000). Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 30-untranslated region. J Biol Chem 275: 11750-11757. (Pubitemid 30237739)
9. Fabian MR, Sonenberg N, Filipowicz W. (2010). Regulation of mRNA translation and stability by microRNAs. Annu Rev Biochem 79: 351-379.
10. Ferguson HR, Wild CP, Anderson LA, Murphy SJ, Johnston BT, Murray LJ et al. (2008). Cyclooxygenase-2 and inducible nitric oxide synthase gene polymorphisms and risk of reflux esophagitis, Barrett0s esophagus, and esophageal adenocarcinoma. Cancer Epidemiol Biomarkers Prev 17: 727-731. (Pubitemid 351469227)
11. Gong Z, Bostick RM, Xie D, Hurley TG, Deng Z, Dixon DA et al. (2009). Genetic polymorphisms in the cyclooxygenase-1 and cyclooxygenase-2 genes and risk of colorectal adenoma. Int J Colorectal Dis 24: 647-654.
12. Guo H, Ingolia NT, Weissman JS, Bartel DP. (2010). Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466: 835-840.
13. Jing Q, Huang S, Guth S, Zarubin T, Motoyama A, Chen J et al. (2005). Involvement of microRNA in AU-rich element-mediated mRNA instability. Cell 120: 623-634. (Pubitemid 40343075)
14. Langsenlehner U, Yazdani-Biuki B, Eder T, Renner W, Wascher TC, Paulweber B et al. (2006). The cyclooxygenase-2 (PTGS2) 8473T>C polymorphism is associated with breast cancer risk. Clin Cancer Res 12: 1392-1394. (Pubitemid 43342533)
15. Menter DG, Schilsky RL, DuBois RN. (2010). Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward. Clin Cancer Res 16: 1384-1390.
16. Nasir A, Kaiser HE, Boulware D, Hakam A, Zhao H, Yeatman T et al. (2004). Cyclooxygenase-2 expression in right-and left-sided colon cancer: a rationale for optimization of cyclooxygenase-2 inhibitor therapy. Clin Colorectal Cancer 3: 243-247. (Pubitemid 38444311)
17. Nicoloso MS, Sun H, Spizzo R, Kim H, Wickramasinghe P, Shimizu M et al. (2010). Single-nucleotide polymorphisms inside microRNA target sites influence tumor susceptibility. Cancer Res 70: 2789-2798.
18. Ozhan G, Yanar TH, Ertekin C, Alpertunga B. (2010). The effect of genetic polymorphisms of cyclooxygenase 2 on acute pancreatitis in Turkey. Pancreas 39: 371-376.
19. Ryan BM, Robles AI, Harris CC. (2010). Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer 10: 389-402.
20. Sanduja S, Kaza V, Dixon DA. (2009). The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirustransformed cervical cancer cells by targeting E6-AP ubiquitin ligase. Aging 1: 803-817.
21. Shen J, Gammon MD, Terry MB, Teitelbaum SL, Neugut AI, Santella RM. (2006). Genetic polymorphisms in the cyclooxygenase-2 gene, use of nonsteroidal anti-inflammatory drugs, and breast cancer risk. Breast Cancer Res 8: 71-80.
22. Siezen CL, van Leeuwen AI, Kram NR, Luken ME, van Kranen HJ, Kampman E. (2005). Colorectal adenoma risk is modified by the interplay between polymorphisms in arachidonic acid pathway genes and fish consumption. Carcinogenesis 26: 449-457. (Pubitemid 40246567)
23. Vogel U, Christensen J, Wallin H, Friis S, Nexo BA, Raaschou-Nielsen O et al. (2008). Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study. Mutat Res 639: 89-100.
24. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F et al. (2006). A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261. (Pubitemid 43271657)
25. Wang D, Dubois RN. (2010). The role of COX-2 in intestinal inflammation and colorectal cancer. Oncogene 29: 781-788.
26. Young LE, Dixon DA. (2010). Posttranscriptional regulation of cyclooxygenase 2 expression in colorectal cancer. Curr Colorectal Cancer Rep 6: 60-67.
27. Young LE, Sanduja S, Bemis-Standoli K, Pena EA, Price RL, Dixon DA. (2009). The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis. Gastroenterology 136: 1669-1679.