메뉴 건너뛰기




Volumn 4, Issue AUG, 2013, Pages

Early detection of simian immunodeficiency virus in the central nervous system following oral administration to rhesus macaques

Author keywords

Acute infection; CNS; HIV; Monkey model; Oral transmission; Rhesus macaque; SIV

Indexed keywords

GENOMIC DNA;

EID: 84883714229     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2013.00236     Document Type: Article
Times cited : (9)

References (46)
  • 1
    • 84870167524 scopus 로고    scopus 로고
    • Neuropathology of AIDS: an autopsy review of 284 cases from Brazil comparing the findings pre- and post-HAART (Highly Active Antiretroviral Therapy) and pre- and postmortem correlation
    • doi:10.1155/2012/186850
    • Silva AC, Rodrigues BS, Micheletti AM, Tostes S Jr, Meneses AC, Silva-Vergara ML, et al. Neuropathology of AIDS: an autopsy review of 284 cases from Brazil comparing the findings pre- and post-HAART (Highly Active Antiretroviral Therapy) and pre- and postmortem correlation. AIDS Res Treat (2012) 2012:186850. doi:10.1155/2012/186850
    • (2012) AIDS Res Treat , vol.2012 , pp. 186850
    • Silva, A.C.1    Rodrigues, B.S.2    Micheletti, A.M.3    Tostes Jr., S.4    Meneses, A.C.5    Silva-Vergara, M.L.6
  • 2
    • 75649100547 scopus 로고    scopus 로고
    • HIV infection and aging independently affect brain function as measured by functional magnetic resonance imaging
    • doi:10.1086/649899
    • Ances BM, Vaida F, Yeh MJ, Liang CL, Buxton RB, Letendre S, et al. HIV infection and aging independently affect brain function as measured by functional magnetic resonance imaging. J Infect Dis (2010) 201:336-40. doi:10.1086/649899
    • (2010) J Infect Dis , vol.201 , pp. 336-340
    • Ances, B.M.1    Vaida, F.2    Yeh, M.J.3    Liang, C.L.4    Buxton, R.B.5    Letendre, S.6
  • 3
    • 3843132957 scopus 로고    scopus 로고
    • Adaptation of the attention network in human immunodeficiency virus brain injury
    • doi:10.1002/ana.20190
    • Chang L, Tomasi D, Yakupov R, Lozar C, Arnold S, Caparelli E, et al. Adaptation of the attention network in human immunodeficiency virus brain injury. Ann Neurol (2004) 56:259-72. doi:10.1002/ana.20190
    • (2004) Ann Neurol , vol.56 , pp. 259-272
    • Chang, L.1    Tomasi, D.2    Yakupov, R.3    Lozar, C.4    Arnold, S.5    Caparelli, E.6
  • 4
    • 0029924748 scopus 로고    scopus 로고
    • HIV-related metabolic abnormalities in the brain: depiction with proton MR spectroscopy with short echo times
    • Laubenberger J, Häussinger D, Bayer S, Thielemann S, Schneider B, Mundinger A, et al. HIV-related metabolic abnormalities in the brain: depiction with proton MR spectroscopy with short echo times. Radiology (1996) 199:805-10.
    • (1996) Radiology , vol.199 , pp. 805-810
    • Laubenberger, J.1    Häussinger, D.2    Bayer, S.3    Thielemann, S.4    Schneider, B.5    Mundinger, A.6
  • 5
    • 0030931165 scopus 로고    scopus 로고
    • Biochemical changes in the frontal lobe of HIV-infected individuals detected by magnetic resonance spectroscopy
    • doi:10.1073/pnas.94.18.9854
    • Lopez-Villegas D, Lenkinski RE, Frank I. Biochemical changes in the frontal lobe of HIV-infected individuals detected by magnetic resonance spectroscopy. Proc Natl Acad Sci U S A (1997) 94:9854-9. doi:10.1073/pnas.94.18.9854
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 9854-9859
    • Lopez-Villegas, D.1    Lenkinski, R.E.2    Frank, I.3
  • 6
    • 34548100033 scopus 로고    scopus 로고
    • Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity
    • doi:10.1176/appi.neuropsych.19.3.283
    • Paul RH, Yiannoutsos CT, Miller EN, Chang L, Marra CM, Schifitto G, et al. Proton MRS and neuropsychological correlates in AIDS dementia complex: evidence of subcortical specificity. J Neuropsychiatry Clin Neurosci (2007) 19:283-92. doi:10.1176/appi.neuropsych.19.3.283
    • (2007) J Neuropsychiatry Clin Neurosci , vol.19 , pp. 283-292
    • Paul, R.H.1    Yiannoutsos, C.T.2    Miller, E.N.3    Chang, L.4    Marra, C.M.5    Schifitto, G.6
  • 7
    • 79960027926 scopus 로고    scopus 로고
    • Alterations in brain metabolism during the first year of HIV infection
    • doi:10.1007/s13365-011-0030-9
    • Lentz MR, Kim WK, Kim H, Soulas C, Lee V, Venna N, et al. Alterations in brain metabolism during the first year of HIV infection. J Neurovirol (2011) 17:220-9. doi:10.1007/s13365-011-0030-9
    • (2011) J Neurovirol , vol.17 , pp. 220-229
    • Lentz, M.R.1    Kim, W.K.2    Kim, H.3    Soulas, C.4    Lee, V.5    Venna, N.6
  • 8
    • 67549130940 scopus 로고    scopus 로고
    • Changes in MRS neuronal markers and T cell phenotypes observed during early HIV infection
    • doi:10.1212/WNL.0b013e3181a2e90a
    • Lentz MR, Kim WK, Lee V, Bazner S, Halpern EF, Venna N, et al. Changes in MRS neuronal markers and T cell phenotypes observed during early HIV infection. Neurology (2009) 72:1465-72. doi:10.1212/WNL.0b013e3181a2e90a
    • (2009) Neurology , vol.72 , pp. 1465-1472
    • Lentz, M.R.1    Kim, W.K.2    Lee, V.3    Bazner, S.4    Halpern, E.F.5    Venna, N.6
  • 9
    • 0026661095 scopus 로고
    • Early viral brain invasion in iatrogenic human immunodeficiency virus infection
    • doi:10.1212/WNL.42.9.1736
    • Davis LE, Hjelle BL, Miller VE, Palmer DL, Llewellyn AL, Merlin TL, et al. Early viral brain invasion in iatrogenic human immunodeficiency virus infection. Neurology (1992) 42:1736-9. doi:10.1212/WNL.42.9.1736
    • (1992) Neurology , vol.42 , pp. 1736-1739
    • Davis, L.E.1    Hjelle, B.L.2    Miller, V.E.3    Palmer, D.L.4    Llewellyn, A.L.5    Merlin, T.L.6
  • 10
    • 0032708190 scopus 로고    scopus 로고
    • Early entry and widespread cellular involvement of HIV-1 DNA in brains of HIV-1 positive asymptomatic individuals
    • doi:10.1097/00005072-199911000-00005
    • An SF, Groves M, Gray F, Scaravilli F. Early entry and widespread cellular involvement of HIV-1 DNA in brains of HIV-1 positive asymptomatic individuals. J Neuropathol Exp Neurol (1999) 58:1156-62. doi:10.1097/00005072-199911000-00005
    • (1999) J Neuropathol Exp Neurol , vol.58 , pp. 1156-1162
    • An, S.F.1    Groves, M.2    Gray, F.3    Scaravilli, F.4
  • 11
    • 84873637980 scopus 로고    scopus 로고
    • Tissue-specific interferon alpha subtype response to SIV infection in brain, spleen, and lung
    • doi:10.1089/jir.2012.0018
    • Zaritsky LA, Dery A, Leong WY, Gama L, Clements JE. Tissue-specific interferon alpha subtype response to SIV infection in brain, spleen, and lung. J Interferon Cytokine Res (2013) 33:24-33. doi:10.1089/jir.2012.0018
    • (2013) J Interferon Cytokine Res , vol.33 , pp. 24-33
    • Zaritsky, L.A.1    Dery, A.2    Leong, W.Y.3    Gama, L.4    Clements, J.E.5
  • 12
    • 0036786355 scopus 로고    scopus 로고
    • The central nervous system as a reservoir for simian immunodeficiency virus (SIV): steady-state levels of SIV DNA in brain from acute through asymptomatic infection
    • doi:10.1086/343768
    • Clements JE, Babas T, Mankowski JL, Suryanarayana K, Piatak M Jr, Tarwater PM, et al. The central nervous system as a reservoir for simian immunodeficiency virus (SIV): steady-state levels of SIV DNA in brain from acute through asymptomatic infection. J Infect Dis (2002) 186:905-13. doi:10.1086/343768
    • (2002) J Infect Dis , vol.186 , pp. 905-913
    • Clements, J.E.1    Babas, T.2    Mankowski, J.L.3    Suryanarayana, K.4    Piatak Jr., M.5    Tarwater, P.M.6
  • 13
    • 77954046747 scopus 로고    scopus 로고
    • Coordinated regulation of SIV replication and immune responses in the CNS
    • doi:10.1371/journal.pone.0008129
    • Witwer KW, Gama L, Li M, Bartizal CM, Queen SE, Varrone JJ, et al. Coordinated regulation of SIV replication and immune responses in the CNS. PLoS ONE (2009) 4:e8129. doi:10.1371/journal.pone.0008129
    • (2009) PLoS ONE , vol.4
    • Witwer, K.W.1    Gama, L.2    Li, M.3    Bartizal, C.M.4    Queen, S.E.5    Varrone, J.J.6
  • 14
    • 9644283128 scopus 로고    scopus 로고
    • Acute SIV infection of the brain leads to upregulation of IL6 and interferon-regulated genes: expression patterns throughout disease progression and impact on neuroAIDS
    • doi:10.1016/j.jneuroim.2004.08.030
    • Roberts ES, Burudi EM, Flynn C, Madden LJ, Roinick KL, Watry DD, et al. Acute SIV infection of the brain leads to upregulation of IL6 and interferon-regulated genes: expression patterns throughout disease progression and impact on neuroAIDS. J Neuroimmunol (2004) 157:81-92. doi:10.1016/j.jneuroim.2004.08.030
    • (2004) J Neuroimmunol , vol.157 , pp. 81-92
    • Roberts, E.S.1    Burudi, E.M.2    Flynn, C.3    Madden, L.J.4    Roinick, K.L.5    Watry, D.D.6
  • 15
    • 38649086733 scopus 로고    scopus 로고
    • Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapy
    • doi:10.1097/QAI.0b013e31815ace97
    • Yilmaz A, Price RW, Spudich S, Fuchs D, Hagberg L, Gisslén M. Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapy. J Acquir Immune Defic Syndr (2008) 47:168-73. doi:10.1097/QAI.0b013e31815ace97
    • (2008) J Acquir Immune Defic Syndr , vol.47 , pp. 168-173
    • Yilmaz, A.1    Price, R.W.2    Spudich, S.3    Fuchs, D.4    Hagberg, L.5    Gisslén, M.6
  • 16
    • 76749136667 scopus 로고    scopus 로고
    • Discordance between cerebral spinal fluid and plasma HIV replication in patients with neurological symptoms who are receiving suppressive antiretroviral therapy
    • doi:10.1086/650538
    • Canestri A, Lescure FX, Jaureguiberry S, Moulignier A, Amiel C, Marcelin AG, et al. Discordance between cerebral spinal fluid and plasma HIV replication in patients with neurological symptoms who are receiving suppressive antiretroviral therapy. Clin Infect Dis (2010) 50:773-8. doi:10.1086/650538
    • (2010) Clin Infect Dis , vol.50 , pp. 773-778
    • Canestri, A.1    Lescure, F.X.2    Jaureguiberry, S.3    Moulignier, A.4    Amiel, C.5    Marcelin, A.G.6
  • 17
    • 0036312534 scopus 로고    scopus 로고
    • Simian immunodeficiency virus encephalitis: analysis of envelope sequences from individual brain multinucleated giant cells and tissue samples
    • doi:10.1006/viro.2002.1395
    • Ryzhova EV, Crino P, Shawver L, Westmoreland SV, Lackner AA, González-Scarano F. Simian immunodeficiency virus encephalitis: analysis of envelope sequences from individual brain multinucleated giant cells and tissue samples. Virology (2002) 297:57-67. doi:10.1006/viro.2002.1395
    • (2002) Virology , vol.297 , pp. 57-67
    • Ryzhova, E.V.1    Crino, P.2    Shawver, L.3    Westmoreland, S.V.4    Lackner, A.A.5    González-Scarano, F.6
  • 18
    • 0028348580 scopus 로고
    • Extensive envelope heterogeneity of simian immunodeficiency virus in tissues from infected macaques
    • Campbell BJ, Hirsch VM. Extensive envelope heterogeneity of simian immunodeficiency virus in tissues from infected macaques. J Virol (1994) 68:3129-37.
    • (1994) J Virol , vol.68 , pp. 3129-3137
    • Campbell, B.J.1    Hirsch, V.M.2
  • 19
    • 33746867131 scopus 로고    scopus 로고
    • Simian immunodeficiency virus envelope compartmentalizes in brain regions independent of neuropathology
    • doi:10.1080/13550280600654565
    • Chen MF, Westmoreland S, Ryzhova EV, Martín-García J, Soldan SS, Lackner A, et al. Simian immunodeficiency virus envelope compartmentalizes in brain regions independent of neuropathology. J Neurovirol (2006) 12:73-89. doi:10.1080/13550280600654565
    • (2006) J Neurovirol , vol.12 , pp. 73-89
    • Chen, M.F.1    Westmoreland, S.2    Ryzhova, E.V.3    Martín-García, J.4    Soldan, S.S.5    Lackner, A.6
  • 20
    • 35348922244 scopus 로고    scopus 로고
    • Dynamics of simian immunodeficiency virus populations in blood and cerebrospinal fluid over the full course of infection
    • doi:10.1086/520819
    • Harrington PR, Connell MJ, Meeker RB, Johnson PR, Swanstrom R. Dynamics of simian immunodeficiency virus populations in blood and cerebrospinal fluid over the full course of infection. J Infect Dis (2007) 196:1058-67. doi:10.1086/520819
    • (2007) J Infect Dis , vol.196 , pp. 1058-1067
    • Harrington, P.R.1    Connell, M.J.2    Meeker, R.B.3    Johnson, P.R.4    Swanstrom, R.5
  • 21
    • 0034701034 scopus 로고    scopus 로고
    • Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources
    • doi:10.1212/WNL.54.4.927
    • Ellis RJ, Gamst AC, Capparelli E, Spector SA, Hsia K, Wolfson T, et al. Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources. Neurology (2000) 54:927-36. doi:10.1212/WNL.54.4.927
    • (2000) Neurology , vol.54 , pp. 927-936
    • Ellis, R.J.1    Gamst, A.C.2    Capparelli, E.3    Spector, S.A.4    Hsia, K.5    Wolfson, T.6
  • 23
    • 0035078787 scopus 로고    scopus 로고
    • Route of simian immunodeficiency virus inoculation determines the complexity but not the identity of viral variant populations that infect rhesus macaques
    • doi:10.1128/JVI.75.8.3753-3765.2001
    • Greenier JL, Miller CJ, Lu D, Dailey PJ, Lü FX, Kunstman KJ, et al. Route of simian immunodeficiency virus inoculation determines the complexity but not the identity of viral variant populations that infect rhesus macaques. J Virol (2001) 75:3753-65. doi:10.1128/JVI.75.8.3753-3765.2001
    • (2001) J Virol , vol.75 , pp. 3753-3765
    • Greenier, J.L.1    Miller, C.J.2    Lu, D.3    Dailey, P.J.4    Lü, F.X.5    Kunstman, K.J.6
  • 24
    • 0034765453 scopus 로고    scopus 로고
    • Titration of an SIVmac251 stock by vaginal inoculation of Indian and Chinese origin rhesus macaques: transmission efficiency, viral loads, and antibody responses
    • doi:10.1089/088922201753197123
    • Marthas ML, Lu D, Penedo MC, Hendrickx AG, Miller CJ. Titration of an SIVmac251 stock by vaginal inoculation of Indian and Chinese origin rhesus macaques: transmission efficiency, viral loads, and antibody responses. AIDS Res Hum Retroviruses (2001) 17:1455-66. doi:10.1089/088922201753197123
    • (2001) AIDS Res Hum Retroviruses , vol.17 , pp. 1455-1466
    • Marthas, M.L.1    Lu, D.2    Penedo, M.C.3    Hendrickx, A.G.4    Miller, C.J.5
  • 25
    • 0037213929 scopus 로고    scopus 로고
    • Immunization of newborn rhesus macaques with simian immunodeficiency virus (SIV) vaccines prolongs survival after oral challenge with virulent SIVmac251
    • doi:10.1128/JVI.77.1.179-190.2003
    • Van Rompay KK, Greenier JL, Cole KS, Earl P, Moss B, Steckbeck JD, et al. Immunization of newborn rhesus macaques with simian immunodeficiency virus (SIV) vaccines prolongs survival after oral challenge with virulent SIVmac251. J Virol (2003) 77:179-90. doi:10.1128/JVI.77.1.179-190.2003
    • (2003) J Virol , vol.77 , pp. 179-190
    • Van Rompay, K.K.1    Greenier, J.L.2    Cole, K.S.3    Earl, P.4    Moss, B.5    Steckbeck, J.D.6
  • 26
    • 34249933019 scopus 로고    scopus 로고
    • Mucosal innate immune response associated with a timely humoral immune response and slower disease progression after oral transmission of simian immunodeficiency virus to rhesus macaques
    • doi:10.1128/JVI.00042-07
    • Milush JM, Stefano-Cole K, Schmidt K, Durudas A, Pandrea I, Sodora DL. Mucosal innate immune response associated with a timely humoral immune response and slower disease progression after oral transmission of simian immunodeficiency virus to rhesus macaques. J Virol (2007) 81:6175-86. doi:10.1128/JVI.00042-07
    • (2007) J Virol , vol.81 , pp. 6175-6186
    • Milush, J.M.1    Stefano-Cole, K.2    Schmidt, K.3    Durudas, A.4    Pandrea, I.5    Sodora, D.L.6
  • 27
    • 20744440829 scopus 로고    scopus 로고
    • The central nervous system is a viral reservoir in simian immunodeficiency virus - infected macaques on combined antiretroviral therapy: a model for human immunodeficiency virus patients on highly active antiretroviral therapy
    • doi:10.1080/13550280590922829
    • Clements JE, Li M, Gama L, Bullock B, Carruth LM, Mankowski JL, et al. The central nervous system is a viral reservoir in simian immunodeficiency virus - infected macaques on combined antiretroviral therapy: a model for human immunodeficiency virus patients on highly active antiretroviral therapy. J Neurovirol (2005) 11:180-9. doi:10.1080/13550280590922829
    • (2005) J Neurovirol , vol.11 , pp. 180-189
    • Clements, J.E.1    Li, M.2    Gama, L.3    Bullock, B.4    Carruth, L.M.5    Mankowski, J.L.6
  • 28
    • 77649195668 scopus 로고    scopus 로고
    • Compartmentalization and clonal amplification of HIV-1 variants in the cerebrospinal fluid during primary infection
    • doi:10.1128/JVI.01863-09
    • Schnell G, Price RW, Swanstrom R, Spudich S. Compartmentalization and clonal amplification of HIV-1 variants in the cerebrospinal fluid during primary infection. J Virol (2010) 84:2395-407. doi:10.1128/JVI.01863-09
    • (2010) J Virol , vol.84 , pp. 2395-2407
    • Schnell, G.1    Price, R.W.2    Swanstrom, R.3    Spudich, S.4
  • 29
    • 0027980442 scopus 로고
    • Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays
    • Delwart EL, Sheppard HW, Walker BD, Goudsmit J, Mullins JI. Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays. J Virol (1994) 68:6672-83.
    • (1994) J Virol , vol.68 , pp. 6672-6683
    • Delwart, E.L.1    Sheppard, H.W.2    Walker, B.D.3    Goudsmit, J.4    Mullins, J.I.5
  • 30
    • 0034658873 scopus 로고    scopus 로고
    • Position and degree of mismatches and the mobility of DNA heteroduplexes
    • doi:10.1093/nar/28.12.e69
    • Upchurch DA, Shankarappa R, Mullins JI. Position and degree of mismatches and the mobility of DNA heteroduplexes. Nucleic Acids Res (2000) 28:E69. doi:10.1093/nar/28.12.e69
    • (2000) Nucleic Acids Res , vol.28
    • Upchurch, D.A.1    Shankarappa, R.2    Mullins, J.I.3
  • 32
    • 77950951770 scopus 로고    scopus 로고
    • Induction of systemic HIV-1-specific cellular immune responses by oral exposure in the uninfected partner of discordant couples
    • doi:10.1097/QAD.0b013e328337aff8
    • Pérez CL, Hasselrot K, Bratt G, Broliden K, Karlsson AC. Induction of systemic HIV-1-specific cellular immune responses by oral exposure in the uninfected partner of discordant couples. AIDS (2010) 24:969-74. doi:10.1097/QAD.0b013e328337aff8
    • (2010) AIDS , vol.24 , pp. 969-974
    • Pérez, C.L.1    Hasselrot, K.2    Bratt, G.3    Broliden, K.4    Karlsson, A.C.5
  • 33
    • 67650770077 scopus 로고    scopus 로고
    • In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain
    • doi:10.1186/1471-2202-10-63
    • Ratai EM, Pilkenton SJ, Greco JB, Lentz MR, Bombardier JP, Turk KW, et al. In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain. BMC Neurosci (2009) 10:63. doi:10.1186/1471-2202-10-63
    • (2009) BMC Neurosci , vol.10 , pp. 63
    • Ratai, E.M.1    Pilkenton, S.J.2    Greco, J.B.3    Lentz, M.R.4    Bombardier, J.P.5    Turk, K.W.6
  • 34
    • 34447338029 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 RNA Levels in different regions of human brain: quantification using real-time reverse transcriptase-polymerase chain reaction
    • doi:10.1080/13550280701327038
    • Kumar AM, Borodowsky I, Fernandez B, Gonzalez L, Kumar M. Human immunodeficiency virus type 1 RNA Levels in different regions of human brain: quantification using real-time reverse transcriptase-polymerase chain reaction. J Neurovirol (2007) 13:210-24. doi:10.1080/13550280701327038
    • (2007) J Neurovirol , vol.13 , pp. 210-224
    • Kumar, A.M.1    Borodowsky, I.2    Fernandez, B.3    Gonzalez, L.4    Kumar, M.5
  • 35
    • 0031594394 scopus 로고    scopus 로고
    • A genetic and viral load analysis of the simian immunodeficiency virus during the acute phase in macaques inoculated by the vaginal route
    • doi:10.1089/aid.1998.14.171
    • Sodora DL, Lee F, Dailey PJ, Marx PA. A genetic and viral load analysis of the simian immunodeficiency virus during the acute phase in macaques inoculated by the vaginal route. AIDS Res Hum Retroviruses (1998) 14:171-81. doi:10.1089/aid.1998.14.171
    • (1998) AIDS Res Hum Retroviruses , vol.14 , pp. 171-181
    • Sodora, D.L.1    Lee, F.2    Dailey, P.J.3    Marx, P.A.4
  • 36
    • 21644455405 scopus 로고    scopus 로고
    • Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus
    • doi:10.1128/JVI.79.14.9217-9227.2005
    • Miller CJ, Li Q, Abel K, Kim EY, Ma ZM, Wietgrefe S, et al. Propagation and dissemination of infection after vaginal transmission of simian immunodeficiency virus. J Virol (2005) 79:9217-27. doi:10.1128/JVI.79.14.9217-9227.2005
    • (2005) J Virol , vol.79 , pp. 9217-9227
    • Miller, C.J.1    Li, Q.2    Abel, K.3    Kim, E.Y.4    Ma, Z.M.5    Wietgrefe, S.6
  • 37
    • 35448994462 scopus 로고    scopus 로고
    • Neuroinvasion of fluorescein-positive monocytes in acute simian immunodeficiency virus infection
    • doi:10.1128/JVI.00133-07
    • Clay CC, Rodrigues DS, Ho YS, Fallert BA, Janatpour K, Reinhart TA, et al. Neuroinvasion of fluorescein-positive monocytes in acute simian immunodeficiency virus infection. J Virol (2007) 81:12040-8. doi:10.1128/JVI.00133-07
    • (2007) J Virol , vol.81 , pp. 12040-12048
    • Clay, C.C.1    Rodrigues, D.S.2    Ho, Y.S.3    Fallert, B.A.4    Janatpour, K.5    Reinhart, T.A.6
  • 38
    • 0742325049 scopus 로고    scopus 로고
    • Impaired performance on a rhesus monkey neuropsychological testing battery following simian immunodeficiency virus infection
    • doi:10.1089/088922204322749521
    • Weed MR, Gold LH, Polis I, Koob GF, Fox HS, Taffe MA. Impaired performance on a rhesus monkey neuropsychological testing battery following simian immunodeficiency virus infection. AIDS Res Hum Retroviruses (2004) 20:77-89. doi:10.1089/088922204322749521
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 77-89
    • Weed, M.R.1    Gold, L.H.2    Polis, I.3    Koob, G.F.4    Fox, H.S.5    Taffe, M.A.6
  • 39
    • 77953724307 scopus 로고    scopus 로고
    • Simian immunodeficiency virus-infected macaques treated with highly active antiretroviral therapy have reduced central nervous system viral replication and inflammation but persistence of viral DNA
    • doi:10.1086/653213
    • Zink MC, Brice AK, Kelly KM, Queen SE, Gama L, Li M, et al. Simian immunodeficiency virus-infected macaques treated with highly active antiretroviral therapy have reduced central nervous system viral replication and inflammation but persistence of viral DNA. J Infect Dis (2010) 202:161-70. doi:10.1086/653213
    • (2010) J Infect Dis , vol.202 , pp. 161-170
    • Zink, M.C.1    Brice, A.K.2    Kelly, K.M.3    Queen, S.E.4    Gama, L.5    Li, M.6
  • 40
    • 34447128097 scopus 로고    scopus 로고
    • The relevance of neuroactive steroids in schizophrenia, depression, and anxiety disorders
    • doi:10.1007/s10571-006-9086-0
    • MacKenzie EM, Odontiadis J, Le Mellédo JM, Prior TI, Baker GB. The relevance of neuroactive steroids in schizophrenia, depression, and anxiety disorders. Cell Mol Neurobiol (2007) 27:541-74. doi:10.1007/s10571-006-9086-0
    • (2007) Cell Mol Neurobiol , vol.27 , pp. 541-574
    • MacKenzie, E.M.1    Odontiadis, J.2    Le Mellédo, J.M.3    Prior, T.I.4    Baker, G.B.5
  • 41
    • 0029025513 scopus 로고
    • Dehydroepiandrosterone inhibits replication of feline immunodeficiency virus in chronically infected cells
    • doi:10.1016/0165-2427(94)07015-Y
    • Bradley WG, Kraus LA, Good RA, Day NK. Dehydroepiandrosterone inhibits replication of feline immunodeficiency virus in chronically infected cells. Vet Immunol Immunopathol (1995) 46:159-68. doi:10.1016/0165-2427(94)07015-Y
    • (1995) Vet Immunol Immunopathol , vol.46 , pp. 159-168
    • Bradley, W.G.1    Kraus, L.A.2    Good, R.A.3    Day, N.K.4
  • 42
    • 0142061180 scopus 로고    scopus 로고
    • 16alpha-Bromo-epiandrosterone therapy modulates experimental feline immunodeficiency virus viremia: initial enhancement leading to long-term suppression
    • doi:10.1016/S0165-2427(03)00081-3
    • Pedersen NC, North TW, Rigg R, Reading C, Higgins J, Leutenegger C, et al. 16alpha-Bromo-epiandrosterone therapy modulates experimental feline immunodeficiency virus viremia: initial enhancement leading to long-term suppression. Vet Immunol Immunopathol (2003) 94:133-48. doi:10.1016/S0165-2427(03)00081-3
    • (2003) Vet Immunol Immunopathol , vol.94 , pp. 133-148
    • Pedersen, N.C.1    North, T.W.2    Rigg, R.3    Reading, C.4    Higgins, J.5    Leutenegger, C.6
  • 43
    • 0027201627 scopus 로고
    • Inhibition of HIV-1 latency reactivation by dehydroepiandrosterone (DHEA) and an analog of DHEA
    • doi:10.1089/aid.1993.9.747
    • Yang JY, Schwartz A, Henderson EE. Inhibition of HIV-1 latency reactivation by dehydroepiandrosterone (DHEA) and an analog of DHEA. AIDS Res Hum Retroviruses (1993) 9:747-54. doi:10.1089/aid.1993.9.747
    • (1993) AIDS Res Hum Retroviruses , vol.9 , pp. 747-754
    • Yang, J.Y.1    Schwartz, A.2    Henderson, E.E.3
  • 44
    • 77950858637 scopus 로고    scopus 로고
    • Microglia in neurodegenerative disease
    • doi:10.1038/nrneurol.2010.17
    • Perry VH, Nicoll JA, Holmes C. Microglia in neurodegenerative disease. Nat Rev Neurol (2010) 6:193-201. doi:10.1038/nrneurol.2010.17
    • (2010) Nat Rev Neurol , vol.6 , pp. 193-201
    • Perry, V.H.1    Nicoll, J.A.2    Holmes, C.3
  • 45
    • 65649111238 scopus 로고    scopus 로고
    • Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates
    • doi:10.2353/ajpath.2009.081010
    • Soulas C, Donahue RE, Dunbar CE, Persons DA, Alvarez X, Williams KC. Genetically modified CD34+ hematopoietic stem cells contribute to turnover of brain perivascular macrophages in long-term repopulated primates. Am J Pathol (2009) 174:1808-17. doi:10.2353/ajpath.2009.081010
    • (2009) Am J Pathol , vol.174 , pp. 1808-1817
    • Soulas, C.1    Donahue, R.E.2    Dunbar, C.E.3    Persons, D.A.4    Alvarez, X.5    Williams, K.C.6
  • 46
    • 38349068747 scopus 로고    scopus 로고
    • Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system
    • doi:10.1001/archneurol.2007.31
    • Letendre S, Marquie-Beck J, Capparelli E, Best B, Clifford D, Collier AC, et al. Validation of the CNS Penetration-Effectiveness rank for quantifying antiretroviral penetration into the central nervous system. Arch Neurol (2008) 65:65-70. doi:10.1001/archneurol.2007.31
    • (2008) Arch Neurol , vol.65 , pp. 65-70
    • Letendre, S.1    Marquie-Beck, J.2    Capparelli, E.3    Best, B.4    Clifford, D.5    Collier, A.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.