Effect of a monofunctional phenanthriplatin-DNA adduct on RNA polymerase II transcriptional fidelity and translesion synthesis

Journal of the American Chemical Society

Volumn 135, Issue 35, 2013, Pages 13054-13061

  Kellinger, Matthew W ^a   Park, Ga Young ^b   Chong, Jenny ^a   Lippard, Stephen J ^b   Wang, Dong ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICANCER ACTIVITIES; INORGANIC CHEMISTRY; MACHINERY COMPONENTS; MECHANISM OF ACTION; PLATINUM ANTICANCER DRUGS; TRANSCRIPTIONAL FIDELITY; TRANSLESION DNA SYNTHESIS; TRANSLESION SYNTHESIS;

CHLORINE COMPOUNDS; INORGANIC COMPOUNDS; MACHINERY; PLATINUM COMPOUNDS; POLYMERS; RNA; TRANSCRIPTION;

DNA;

ADENOSINE TRIPHOSPHATE; ANTINEOPLASTIC AGENT; CISPLATIN DERIVATIVE; CYTIDINE TRIPHOSPHATE; DNA POLYMERASE; DOUBLE STRANDED DNA; GUANOSINE TRIPHOSPHATE; PHENANTHRIDINE DERIVATIVE; PHENANTHRIPLATIN; PLATINUM; PRIMER RNA; PYROPHOSPHATE; RNA POLYMERASE II; UNCLASSIFIED DRUG; URIDINE TRIPHOSPHATE;

ARTICLE; BASE PAIRING; DNA ADDUCT; DNA DAMAGE; DNA DAMAGE CHECKPOINT; DNA SYNTHESIS; DNA TEMPLATE; IN VITRO STUDY; INCUBATION TIME; INORGANIC CHEMISTRY; RNA PROCESSING; RNA SYNTHESIS; RNA TRANSCRIPTION; ROOM TEMPERATURE; STEREOSPECIFICITY; TRANSCRIPTION ELONGATION;

DNA ADDUCTS; DNA DAMAGE; MOLECULAR STRUCTURE; ORGANOPLATINUM COMPOUNDS; PHENANTHRIDINES; RNA POLYMERASE II; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC;

EID: 84883689904     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja405475y     Document Type: Article

References (53)

1. Wang, D.; Lippard, S. J. Nat. Rev. Drug Discov. 2005, 4, 307
2. Todd, R. C.; Lippard, S. J. Metallomics 2009, 1, 280
3. Brabec, V.; Kasparkova, J. Drug Resist. Updat. 2005, 8, 131
4. Reedijk, J. Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 3611
5. Aris, S. M.; Farrell, N. P. Eur. J. Inorg. Chem. 2009, 2009, 1293
6. Kelland, L. Nat. Rev. Cancer 2007, 7, 573
7. Svejstrup, J. Q. Trends Biochem. Sci. 2007, 32, 165
8. Hanawalt, P. C.; Spivak, G. Nat. Rev. Mol. Cell Biol. 2008, 9, 958
9. Saxowsky, T. T.; Doetsch, P. W. Chem. Rev. 2006, 106, 474
10. Jamieson, E. R.; Lippard, S. J. Chem. Rev. 1999, 99, 2467
11. Jung, Y. W.; Lippard, S. J. Chem. Rev. 2007, 107, 1387
12. Lovejoy, K. S.; Lippard, S. J. Dalton Trans. 2009, 10651
13. Lovejoy, K. S.; Todd, R. C.; Zhang, S.; McCormick, M. S.; D'Aquino, J. A.; Reardon, J. T.; Sancar, A.; Giacomini, K. M.; Lippard, S. J. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 8902
14. Wang, D.; Zhu, G.; Huang, X.; Lippard, S. J. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 9584
15. Park, G. Y.; Wilson, J. J.; Song, Y.; Lippard, S. J. Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 11987
16. Zhu, G. Y.; Myint, M.; Ang, W. H.; Song, L.; Lippard, S. J. Cancer Res. 2012, 72, 790
17. Gnatt, A. L.; Cramer, P.; Fu, J.; Bushnell, D. A.; Kornberg, R. D. Science 2001, 292, 1876
18. Kettenberger, H.; Armache, K.-J.; Cramer, P. Mol. Cell 2004, 16, 955
19. Westover, K. D.; Bushnell, D. A.; Kornberg, R. D. Cell 2004, 119, 481
20. Wang, D.; Bushnell, D. A.; Westover, K. D.; Kaplan, C. D.; Kornberg, R. D. Cell 2006, 127, 941
21. Brueckner, F.; Cramer, P. Nat. Struct. Mol. Biol. 2008, 15, 811
22. Kaplan, C. D.; Larsson, K.-M.; Kornberg, R. D. Mol. Cell 2008, 30, 547
23. Kireeva, M. L.; Nedialkov, Y. A.; Cremona, G. H.; Purtov, Y. A.; Lubkowska, L.; Malagon, F.; Burton, Z. F.; Strathern, J. N.; Kashlev, M. Mol. Cell 2008, 30, 557
24. Sydow, J. F.; Brueckner, F.; Cheung, A. C.; Damsma, G. E.; Dengl, S.; Lehmann, E.; Vassylyev, D.; Cramer, P. Mol. Cell 2009, 34, 710
25. Walmacq, C.; Kireeva, M. L.; Irvin, J.; Nedialkov, Y.; Lubkowska, L.; Malagon, F.; Strathern, J. N.; Kashlev, M. J. Biol. Chem. 2009, 284, 19601
26. Wang, D.; Bushnell, D. A.; Huang, X.; Westover, K. D.; Levitt, M.; Kornberg, R. D. Science 2009, 324, 1203
27. Huang, X.; Wang, D.; Weiss, D. R.; Bushnell, D. A.; Kornberg, R. D.; Levitt, M. Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 15745
28. Cheung, A. C.; Cramer, P. Nature 2011, 471, 249
29. Da, L. T.; Wang, D.; Huang, X. J. Am. Chem. Soc. 2012, 134, 2399
30. Kaplan, C. D.; Jin, H.; Zhang, I. L.; Belyanin, A. PLoS Genet. 2012, 8, e1002627
31. Kellinger, M. W.; Song, C. X.; Chong, J.; Lu, X. Y.; He, C.; Wang, D. Nat. Struct. Mol. Biol. 2012, 19, 831
32. Kellinger, M. W.; Ulrich, S.; Chong, J.; Kool, E. T.; Wang, D. J. Am. Chem. Soc. 2012, 134, 8231
33. Larson, M. H.; Zhou, J.; Kaplan, C. D.; Palangat, M.; Kornberg, R. D.; Landick, R.; Block, S. M. Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 6555
34. Walmacq, C.; Cheung, A. C.; Kireeva, M. L.; Lubkowska, L.; Ye, C.; Gotte, D.; Strathern, J. N.; Carell, T.; Cramer, P.; Kashlev, M. Mol. Cell 2012, 46, 18
35. Tornaletti, S.; Hanawalt, P. C. Biochimie 1999, 81, 139
36. Kunkel, T. A.; Schaaper, R. M.; Loeb, L. A. Biochemistry 1983, 22, 2378
37. Schaaper, R. M.; Kunkel, T. A.; Loeb, L. A. Proc. Natl. Acad. Sci. U.S.A. 1983, 80, 487
38. Loeb, L. A.; Preston, B. D. Annu. Rev. Genet. 1986, 20, 201
39. Strauss, B. S. Bioessays 1991, 13, 79
40. Goodman, M. F.; Cai, H.; Bloom, L. B.; Eritja, R. Ann. N.Y. Acad. Sci. 1994, 726, 132
41. Strauss, B. S. DNA Repair 2002, 1, 125
42. Yang, W.; Woodgate, R. Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 15591
43. Obeid, S.; Blatter, N.; Kranaster, R.; Schnur, A.; Diederichs, K.; Welte, W.; Marx, A. EMBO J. 2010, 29, 1738
44. Efrati, E.; Tocco, G.; Eritja, R.; Wilson, S. H.; Goodman, M. F. J. Biol. Chem. 1997, 272, 2559
45. Tang, M.; Pham, P.; Shen, X.; Taylor, J. S.; O'Donnell, M.; Woodgate, R.; Goodman, M. F. Nature 2000, 404, 1014
46. Choi, J. Y.; Lim, S.; Kim, E. J.; Jo, A.; Guengerich, F. P. J. Mol. Biol. 2010, 404, 34
47. Saeki, H.; Svejstrup, J. Q. Mol. Cell 2009, 35, 191
48. Dutta, D.; Shatalin, K.; Epshtein, V.; Gottesman, M. E.; Nudler, E. Cell 2011, 146, 533
49. Hobson, D. J.; Wei, W.; Steinmetz, L. M.; Svejstrup, J. Q. Mol. Cell 2012, 48, 365
50. Wilson, M. D.; Harreman, M.; Svejstrup, J. Q. Biochim. Biophys. Acta 2013, 1829, 151
51. Donahue, B. A.; Fuchs, R. P.; Reines, D.; Hanawalt, P. C. J. Biol. Chem. 1996, 271, 10588
52. Perlow, R. A.; Broyde, S. J. Mol. Biol. 2002, 322, 291
53. Schinecker, T. M.; Perlow, R. A.; Broyde, S.; Geacintov, N. E.; Scicchitano, D. A. Nucleic Acids Res. 2003, 31, 6004