The relationship between glucose metabolism, metabolic syndrome, and bone-specific alkaline phosphatase: A structural equation modeling approach

Journal of Clinical Endocrinology and Metabolism

Volumn 98, Issue 9, 2013, Pages 3856-3863

  Cheung, Ching Lung ^a   Tan, Kathryn C B ^b,c   Lam, Karen S L ^b,c   Cheung, Bernard M Y ^a,c  

^a QUEEN MARY HOSPITAL   (Hong Kong)

^b Department of Medicine   (Hong Kong)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN;

ADULT; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; GLUCOSE METABOLISM; HOMEOSTASIS MODEL ASSESSMENT FOR INSULIN RESISTANCE; HUMAN; HYPERTENSION; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; MEAN ARTERIAL PRESSURE; METABOLIC SYNDROME X; OBESITY; PANCREAS ISLET BETA CELL; POPULATION; PRIORITY JOURNAL; STRUCTURAL EQUATION MODEL; UNITED STATES;

ADULT; ALKALINE PHOSPHATASE; BLOOD GLUCOSE; BONE AND BONES; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN; INSULIN RESISTANCE; METABOLIC SYNDROME X; MODELS, BIOLOGICAL; NUTRITION SURVEYS; UNITED STATES;

EID: 84883681150     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-2024     Document Type: Article

References (40)

1. Shao JS, Cheng SL, Sadhu J, Towler DA. Inflammation and the osteogenic regulation of vascular calcification: a review and perspective. Hypertension. 2010;55:579-592.
2. Silva JA, Escobar A, Collins TJ, Ramee SR, White CJ. Unstable angina. A comparison of angioscopic findings between diabetic and nondiabetic patients. Circulation. 1995;92:1731-1736.
3. Marso SP, Mercado N, Maehara A, et al. Plaque composition and clinical outcomes in acute coronary syndrome patients with metabolic syndrome or diabetes. JACC Cardiovasc Imaging. 2012;5: S42-S52.
4. Wong ND, Nelson JC, Granston T, et al. Metabolic syndrome, diabetes, and incidence and progression of coronary calcium: the Multiethnic Study of Atherosclerosis study. JACC Cardiovasc Imaging. 2012;5:358-366.
5. Johnson K, PolewskiM,van Etten D, Terkeltaub R. Chondrogenesis mediated by PPi depletion promotes spontaneous aortic calcification in NPP1/ mice. Arterioscler Thromb Vasc Biol. 2005;25:686-691.
6. Hui M, Li SQ, Holmyard D, Cheng P. Stable transfection of nonosteogenic cell lines with tissue nonspecific alkaline phosphatase enhances mineral deposition both in the presence and absence of-glycerophosphate: possible role for alkaline phosphatase in pathological mineralization. Calcif Tissue Int. 1997;60:467-472.
7. Narisawa S, Harmey D, Yadav MC, O'Neill WC, Hoylaerts MF, Millan JL. Novel inhibitors of alkaline phosphatase suppress vascular smooth muscle cell calcification. J Bone Miner Res. 2007;22: 1700-1710.
8. Ho AM, Johnson MD, Kingsley DM. Role of the mouse ank gene in control of tissue calcification and arthritis. Science. 2000;289:265-270.
9. Sage AP, Tintut Y, Demer LL. Regulatory mechanisms in vascular calcification. Nat Rev Cardiol. 2010;7:528-536.
10. Tonelli M, Curhan G, Pfeffer M, et al. Relation between alkaline phosphatase, serum phosphate, and all-cause or cardiovascular mortality. Circulation. 2009;120:1784-1792.
11. Park JB, Kang DY, Yang HM, et al. 2013 Serum alkaline phosphatase is a predictor of mortality, myocardial infarction, or stent thrombosis after implantation of coronary drug-eluting stent. Eur Heart J. 2013;34:920-931.
12. Bervoets AR, Spasovski GB, Behets GJ, et al. Useful biochemical markers for diagnosing renal osteodystrophy in predialysis endstage renal failure patients. Am J Kidney Dis. 2003;41:997-1007.
13. National Center for Health Statistics National Health and Nutrition Examination Survey Data. Centers for Disease Control and Prevention website. http://www.cdc.gov/nchs/nhanes/nhanes-questionnaires. htm. Accessed March 20, 2013.
14. Levy JC, Matthews DR, Hermans MP. Correct homeostasis model assessment (HOMA) evaluation uses the computer program. Diabetes Care. 1998;21:2191-2192.
15. Bedogni G, Bellentani S, Miglioli L, et al. The Fatty Liver Index: a simple and accurate predictor of hepatic steatosis in the general population. BMC Gastroenterol. 2006;6:33.
16. Lin LY, Kuo HK, Li HY, Hwang JJ, Lin JW. Confirming a biological pathway in the metabolic syndrome: insight from the NHANES 1999-2002. Obesity (Silver Spring). 2008;16:2676-2681.
17. Kline RB. Measurement models and confirmatory factor analysis. In:Principles and Practice of Structural Equation Modeling . 2nd ed. New York: Guilford Press; 2005:133-145.
18. Hu LT, Bentler PM. Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Equ Modeling. 1999;6:1-55.
19. Yang J, Zhang X, Wang W, Liu J. Insulin stimulates osteoblast proliferation and differentiation through ERK and PI3K in MG-63 cells. Cell Biochem Funct. 2010;28:334-341.
20. Hie M, Iitsuka N, Otsuka T, Tsukamoto I. Insulin-dependent diabetes mellitus decreases osteoblastogenesis associated with the inhibition of Wnt signaling through increased expression of Sost and Dkk1 and inhibition of Akt activation. Int J Mol Med. 2011;28: 455-462.
21. Zhen D, Chen Y, Tang X. Metformin reverses the deleterious effects of high glucose on osteoblast function. J Diabetes Complications. 2010;24:334-344.
22. Webber M, Krishnan A, Thomas NG, Cheung BM. Association between serum alkaline phosphatase and C-reactive protein in the United States National Health and Nutrition Examination Survey 2005-2006. Clin Chem Lab Med. 2010;48:167-173.
23. Cheung BM, Ong KL, Cheung RV, et al. Association between plasma alkaline phosphatase and C-reactive protein in Hong Kong Chinese. Clin Chem Lab Med. 2008;46:523-527.
24. Kanazawa I, Yamaguchi T, Yamamoto M, et al. Serum osteocalcin level is associated with glucose metabolism and atherosclerosis parameters in type 2 diabetes mellitus. J Clin Endocrinol Metab. 2009; 94:45-49.
25. García-Martín A, Cortés-Berdonces M, Luque-Fernandez I, Rozas- Moreno P, Quesada-CharnecoM,Munoz-TorresM.Osteocalcin as a marker of metabolic risk in healthy postmenopausal women. Menopause. 2011;18:537-541.
26. Regidor DL, Kovesdy CP, Mehrotra R, et al. Serum alkaline phosphatase predicts mortality among maintenance hemodialysis patients. J Am Soc Nephrol. 2008;19:2193-2203.
27. Ryu WS, Lee SH, Kim CK, Kim BJ, Yoon BW. Increased serum alkaline phosphatase as a predictor of long-Term mortality after stroke. Neurology. 2010;75:1995-2002.
28. Abramowitz M, Muntner P, Coco M, et al. Serum alkaline phosphatase and phosphate and risk of mortality and hospitalization. Clin J Am Soc Nephrol. 2010;5:1064-1071.
29. Shimizu Y, Imano H, Ohira T, et al. CIRCS Investigators. 2012 Alkaline phosphatase and risk of stroke among Japanese: the Circulatory Risk in Communities Study (CIRCS) [published online July 30, 2012]. J Stroke Cerebrovasc Dis. doi:10.1016/j.jstrokecerebrovasdis. 2012.06.009.
30. Shantouf R, Kovesdy CP, Kim Y, et al. Association of serum alkaline phosphatase with coronary artery calcification in maintenance hemodialysis patients. Clin J Am Soc Nephrol. 2009;4:1106-1114.
31. Cheung BM, Ong KL, Wong LY. Elevated serum alkaline phosphatase and peripheral arterial disease in the United States National Health and Nutrition Examination Survey 1999-2004. Int J Cardiol. 2009;135:156-161.
32. Iba K, Takada J, Yamashita T. The serum level of bone-specific alkaline phosphatase activity is associated with aortic calcification in osteoporosis patients. J Bone Miner Metab. 2004;22:594-596.
33. Drechsler C, VerduijnM,Pilz S, et al. Bone alkaline phosphatase and mortality in dialysis patients. Clin JAmSoc Nephrol. 2011;6:1752-1759.
34. Cheung CL, Livshits G, Zhou Y, et al. Hip geometry variation is associated with bone mineralization pathway gene variants: The Framingham Study. J Bone Miner Res. 2010;25:1564-1571.
35. Hernandez JL, Olmos JM, Pariente E, et al. Metabolic syndrome and bone metabolism: the Camargo Cohort study. Menopause. 2010; 17:955-961.
36. Jeon YK, Lee JG, Kim SS, et al. Association between bone mineral density and metabolic syndrome in pre- and postmenopausal women. Endocr J. 2011;58:87-93.
37. Hossain A, Jung LK. Expression of bone specific alkaline phosphatase on human B cells. Cell Immunol. 2008;253:66-70.
38. Shioi A, Katagi M, Okuno Y, et al. Induction of bone-Type alkaline phosphatase in human vascular smooth muscle cells: roles of tumor necrosis factor- and oncostatinMderived from macrophages. Circ Res. 2002;91:9-16.
39. Lindström J,NeumannA, Sheppard KE, et al. Take action to prevent diabetes-The IMAGE toolkit for the prevention of type 2 diabetes in Europe. Horm Metab Res. 2010;42(Suppl 1):S37-S55.
40. Schwarz PE, Greaves CJ, Lindstrom J, Yates T, Davies MJ. Nonpharmacological interventions for the prevention of type 2 diabetes mellitus. Nat Rev Endocrinol. 2012;8:363-373.