PIKfyve Regulates the Endosomal Localization of CpG Oligodeoxynucleotides to Elicit TLR9-Dependent Cellular Responses

PLoS ONE

Volumn 8, Issue 9, 2013, Pages

  Hazeki, Kaoru ^a   Uehara, Masami ^a   Nigorikawa, Kiyomi ^a   Hazeki, Osamu ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; EARLY ENDOSOME ANTIGEN 1; ENZYME INHIBITOR; I KAPPA B KINASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOTRANSFERASE; PIKFYVE; SHORT HAIRPIN RNA; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; YM 201636;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOSOME; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; GENE EXPRESSION; GENE SILENCING; INTRACELLULAR SIGNALING; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

AMINOPYRIDINES; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CYTOKINES; ENDOSOMES; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HETEROCYCLIC COMPOUNDS, 3-RING; MACROPHAGES, PERITONEAL; MICE; OLIGODEOXYRIBONUCLEOTIDES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN BINDING; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9;

EID: 84883651939     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073894     Document Type: Article

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