High-affinity inhibitors of Zymomonas mobilis tRNA-guanine transglycosylase through convergent optimization

Acta Crystallographica Section D: Biological Crystallography

Volumn 69, Issue 9, 2013, Pages 1798-1807

  Barandun, Luzi Jakob ^a   Immekus, Florian ^b   Kohler, Philipp C ^a   Ritschel, Tina ^b   Heine, Andreas ^b   Orlando, Pierfrancesco ^a   Klebe, Gerhard ^b   Diederich, François ^a  

^a ETH ZURICH   (Switzerland)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

lin benzopurine inhibitors; shigellosis; tRNA guanine transglycosylase; Zymomonas mobilis

Indexed keywords

DRUG DERIVATIVE; GLYCOSYLTRANSFERASE; GUANINE; QUEUINE; QUEUINE TRNA RIBOSYLTRANSFERASE; QUEUINE TRNA-RIBOSYLTRANSFERASE;

ARTICLE; BINDING COMPETITION; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; LIN-BENZOPURINE INHIBITORS; METABOLISM; PROTEIN BINDING; SHIGELLOSIS; TRNA-GUANINE TRANSGLYCOSYLASE; X RAY CRYSTALLOGRAPHY; ZYMOMONAS; ZYMOMONAS MOBILIS;

LIN-BENZOPURINE INHIBITORS; SHIGELLOSIS; TRNA-GUANINE TRANSGLYCOSYLASE; ZYMOMONAS MOBILIS;

BINDING, COMPETITIVE; CRYSTALLOGRAPHY, X-RAY; GUANINE; PENTOSYLTRANSFERASES; PROTEIN BINDING; ZYMOMONAS;

EID: 84883566750     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444913014509     Document Type: Article

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