An Integrative Approach Combining Noncovalent Mass Spectrometry, Enzyme Kinetics and X-ray Crystallography to Decipher Tgt Protein-Protein and Protein-RNA Interaction

Journal of Molecular Biology

Volumn 393, Issue 4, 2009, Pages 833-847

  Ritschel, Tina ^a   Atmanene, Cédric ^b   Reuter, Klaus ^a   Van Dorsselaer, Alain ^b   Sanglier Cianferani, Sarah ^b   Klebe, Gerhard ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

noncovalent mass spectrometry; protein protein interaction; protein RNA interaction; tRNA modification; X ray crystallography

Indexed keywords

GLYCOSYLTRANSFERASE; GUANINE TRANSGLYCOSYLASE; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; BINDING KINETICS; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME KINETICS; MASS SPECTROMETRY; OLIGOMERIZATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE; PROTEIN RNA BINDING; STOICHIOMETRY; X RAY CRYSTALLOGRAPHY;

SHIGELLA;

BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; GUANINE; ISOMERASES; MASS SPECTROMETRY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; PENTOSYLTRANSFERASES; POINT MUTATION; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; RNA, TRANSFER;

EID: 70349825989     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2009.07.040     Document Type: Article

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