메뉴 건너뛰기




Volumn 4, Issue JUN, 2013, Pages

A network model for the specification of vulval precursor cells and cell fusion control in Caenorhabditis elegans

Author keywords

Caenorhabditis model; Caenorhabditis VPCs; Discrete state network model; Regulatory networks; Vulval precursor cells

Indexed keywords


EID: 84883564618     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2013.00112     Document Type: Article
Times cited : (12)

References (131)
  • 1
    • 0036637658 scopus 로고    scopus 로고
    • The zinc finger protein REF-2 functions with the Hox genes to inhibit cell fusion in the ventral epidermis of C
    • Alper, S., and Kenyon, C. (2002). The zinc finger protein REF-2 functions with the Hox genes to inhibit cell fusion in the ventral epidermis of C. elegans. Development 129, 3335-3348.
    • (2002) elegans. Development , vol.129 , pp. 3335-3348
    • Alper, S.1    Kenyon, C.2
  • 3
    • 0025946824 scopus 로고
    • Multiple functions of let-23, a Caenorhabditis elegans receptor tyrosine kinase gene required for vulval induction
    • Aroian, R. V., and Sternberg, P. W. (1991). Multiple functions of let-23, a Caenorhabditis elegans receptor tyrosine kinase gene required for vulval induction. Genetics 128, 251-267.
    • (1991) Genetics , vol.128 , pp. 251-267
    • Aroian, R.V.1    Sternberg, P.W.2
  • 4
    • 0029585636 scopus 로고
    • The Caenorhabditis elegans gene lin-1 encodes an ETS-domai.n protein and defines a branch of the vulval induction pathway.
    • doi: 10.1101/gad.9.24.3149
    • Beitel, G. J., Tuck, S., Greenwald, I., and Horvitz, H. R. (1995). The Caenorhabditis elegans gene lin-1 encodes an ETS-domai.n protein and defines a branch of the vulval induction pathway. Genes Dev. 9, 3149-3162. doi: 10.1101/gad.9.24.3149
    • (1995) Genes Dev. , vol.9 , pp. 3149-3162
    • Beitel, G.J.1    Tuck, S.2    Greenwald, I.3    Horvitz, H.R.4
  • 5
    • 0035137910 scopus 로고    scopus 로고
    • Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C
    • doi: 10.1126/science.1055642
    • Berset, T., Hoier, E. F., Battu, G., Canevascini, S., and Hajnal, A. (2001). Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval developmen. Science 291, 1055-1058. doi: 10.1126/science.1055642
    • (2001) elegans vulval developmen. Science , vol.291 , pp. 1055-1058
    • Berset, T.1    Hoier, E.F.2    Battu, G.3    Canevascini, S.4    Hajnal, A.5
  • 6
    • 0031917476 scopus 로고    scopus 로고
    • EGL-17(FGF) expression coordinates the attraction of the migrating sex myoblasts with vulval induction in C
    • Burdine, R. D., Branda, C. S., and Stern, M. J. (1998). EGL-17(FGF) expression coordinates the attraction of the migrating sex myoblasts with vulval induction in C. elegans. Development 125, 1083-1093.
    • (1998) elegans. Development , vol.125 , pp. 1083-1093
    • Burdine, R.D.1    Branda, C.S.2    Stern, M.J.3
  • 7
    • 0030987240 scopus 로고    scopus 로고
    • egl-17 encodes an invertebrate fibroblast growth factor family member required specifically for sex myoblast migration in Caenorhabditis elegans
    • doi: 10.1073/pnas.94.6.2433
    • Burdine, R. D., Chen, E. B., Kwok, S. F., and Stern, M. J. (1997). egl-17 encodes an invertebrate fibroblast growth factor family member required specifically for sex myoblast migration in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 94, 2433-2437. doi: 10.1073/pnas.94.6.2433
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 2433-2437
    • Burdine, R.D.1    Chen, E.B.2    Kwok, S.F.3    Stern, M.J.4
  • 8
    • 0027182311 scopus 로고
    • The Caenorbabditis elegans homeobox gene cluster
    • Bürglin, T. R., and Ruvkun, G. (1993). The Caenorbabditis elegans homeobox gene cluster. Curr. Opin. Genet. Dev. 3, 615-620.
    • (1993) Curr. Opin. Genet. Dev. , vol.3 , pp. 615-620
    • Bürglin, T.R.1    Ruvkun, G.2
  • 9
    • 0034601059 scopus 로고    scopus 로고
    • Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals
    • doi: 10.1093/emboj/19.13.3283
    • Chang, C., Hopper, N. A., and Sternberg, P. W. (2000). Caenorhabditis elegans SOS-1 is necessary for multiple RAS-mediated developmental signals. EMBO J. 19, 3283-3294. doi: 10.1093/emboj/19.13.3283
    • (2000) EMBO J. , vol.19 , pp. 3283-3294
    • Chang, C.1    Hopper, N.A.2    Sternberg, P.W.3
  • 11
    • 0030014642 scopus 로고    scopus 로고
    • lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H)
    • Christensen, S., Kodoyianni, V., Bosenberg, M., Friedman, L., and Kimble, J. (1996). lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H). Development 122, 1373-1383.
    • (1996) Development , vol.122 , pp. 1373-1383
    • Christensen, S.1    Kodoyianni, V.2    Bosenberg, M.3    Friedman, L.4    Kimble, J.5
  • 12
    • 0031081233 scopus 로고    scopus 로고
    • Caenorhabditis elegans HOM-C genes regulate the response of vulval precursor cells to inductive signal
    • doi: 10.1006/dbio.1996.8471
    • Clandinin, T. R., Katz, W. S., and Sternberg, P. W. (1997). Caenorhabditis elegans HOM-C genes regulate the response of vulval precursor cells to inductive signal. Dev. Biol. 182, 150-161. doi: 10.1006/dbio.1996.8471
    • (1997) Dev. Biol. , vol.182 , pp. 150-161
    • Clandinin, T.R.1    Katz, W.S.2    Sternberg, P.W.3
  • 13
    • 0027220590 scopus 로고
    • Control of cell fates in the central body region of C
    • doi: 10.1016/0092-8674(93)90293-Y
    • Clark, S. G., Chisholm, A. D., and Horvitz, H. R. (1993). Control of cell fates in the central body region of C. elegans by the homebox gene lin-39. Cell 74, 43-55. doi: 10.1016/0092-8674(93)90293-Y
    • (1993) elegans by the homebox gene lin-39. Cell , vol.74 , pp. 43-55
    • Clark, S.G.1    Chisholm, A.D.2    Horvitz, H.R.3
  • 14
    • 0026608178 scopus 로고
    • C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains
    • doi: 10.1038/356340a0
    • Clark, S. G., Stern, M. J., and Horvitz, H. R. (1992). C. elegans cell-signalling gene sem-5 encodes a protein with SH2 and SH3 domains. Nature 356, 340-344. doi: 10.1038/356340a0
    • (1992) Nature , vol.356 , pp. 340-344
    • Clark, S.G.1    Stern, M.J.2    Horvitz, H.R.3
  • 15
    • 0037403529 scopus 로고    scopus 로고
    • Cis regulatory requirements for vulval cell-specific expression of the Caenorhabditis elegans fibroblast growth factor gene egl-17
    • doi: 10.1016/S0012-1606(03)00033-2
    • Cui, M., and Han, M. (2003). Cis regulatory requirements for vulval cell-specific expression of the Caenorhabditis elegans fibroblast growth factor gene egl-17. Dev. Biol. 257, 104-116. doi: 10.1016/S0012-1606(03)00033-2
    • (2003) Dev. Biol. , vol.257 , pp. 104-116
    • Cui, M.1    Han, M.2
  • 16
    • 11844256435 scopus 로고    scopus 로고
    • lin-17/Frizzled and lin-18 regulate POP-1/TCF-1 localization and cell type specification during C
    • doi: 10.1016/j.ydbio.2004.10.020
    • Deshpande, R., Inoue, T., Priess, J. R., and Hill, R. J. (2005). lin-17/Frizzled and lin-18 regulate POP-1/TCF-1 localization and cell type specification during C. elegans vulval development. Dev. Biol. 278, 118-129. doi: 10.1016/j.ydbio.2004.10.020
    • (2005) elegans vulval development. Dev. Biol. , vol.278 , pp. 118-129
    • Deshpande, R.1    Inoue, T.2    Priess, J.R.3    Hill, R.J.4
  • 17
    • 0034608814 scopus 로고    scopus 로고
    • SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans
    • doi: 10.1073/pnas.97.14.7877
    • Doyle, T. G., Wen, C., and Greenwald, I. (2000). SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 97, 7877-7881. doi: 10.1073/pnas.97.14.7877
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 7877-7881
    • Doyle, T.G.1    Wen, C.2    Greenwald, I.3
  • 18
    • 33746396416 scopus 로고    scopus 로고
    • Wnt signaling. WormBook, ed The C. elegans Research Community, WormBook. doi: 10.1895/wormbook.1.7.1
    • Eisenmann, D. M. (2005). Wnt signaling. WormBook, ed The C. elegans Research Community, WormBook. doi: 10.1895/wormbook.1.7.1
    • (2005)
    • Eisenmann, D.M.1
  • 19
    • 0031685774 scopus 로고    scopus 로고
    • The /beta-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development
    • Eisenmann, D. M., Maloof, J. N., Simske, J. S., Kenyon, C., and Kim, S. K. (1998). The /beta-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development. Development 125, 3667-3680.
    • (1998) Development , vol.125 , pp. 3667-3680
    • Eisenmann, D.M.1    Maloof, J.N.2    Simske, J.S.3    Kenyon, C.4    Kim, S.K.5
  • 20
    • 0029813901 scopus 로고    scopus 로고
    • Reversal of cell fate determination in Caenorhabditis elegans vulval development
    • Euling, S., and Ambros, V. (1996). Reversal of cell fate determination in Caenorhabditis elegans vulval development. Development 122, 2507-2515.
    • (1996) Development , vol.122 , pp. 2507-2515
    • Euling, S.1    Ambros, V.2
  • 21
    • 84864945923 scopus 로고    scopus 로고
    • Caenorhabditis elegans vulval cell fate patterning
    • doi: 10.1088/1478-3975/9/4/045001
    • Félix, M.-A. (2012). Caenorhabditis elegans vulval cell fate patterning. Phys. Biol. 9:045001. doi: 10.1088/1478-3975/9/4/045001
    • (2012) Phys. Biol. , vol.9 , pp. 045001
    • Félix, M.-A.1
  • 22
    • 84859001285 scopus 로고    scopus 로고
    • Robustness and flexibility in nematode vulva development
    • doi: 10.1016/j.tig.2012.01.002
    • Félix, M.-A., and Barkoulas, M. (2012). Robustness and flexibility in nematode vulva development. Trends Genet. 28, 185-195. doi: 10.1016/j.tig.2012.01.002
    • (2012) Trends Genet. , vol.28 , pp. 185-195
    • Félix, M.-A.1    Barkoulas, M.2
  • 23
    • 0022065262 scopus 로고
    • Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans
    • Ferguson, E. L., and Horvitz, H. R. (1985). Identification and characterization of 22 genes that affect the vulval cell lineages of the nematode Caenorhabditis elegans. Genetics 110, 17-72.
    • (1985) Genetics , vol.110 , pp. 17-72
    • Ferguson, E.L.1    Horvitz, H.R.2
  • 24
    • 84855367309 scopus 로고    scopus 로고
    • Hybrid modeling of cell signaling and transcriptional reprogramming and its application in C
    • doi: 10.3389/fgene.2011.00077
    • Fertig, E. J., Danilova, L. V., Favorov, A. V., and Ochs, M. F. (2011). Hybrid modeling of cell signaling and transcriptional reprogramming and its application in C. elegans development. Front. Genet. 2, 1-9. doi: 10.3389/fgene.2011.00077
    • (2011) elegans development. Front. Genet. , vol.2 , pp. 1-9
    • Fertig, E.J.1    Danilova, L.V.2    Favorov, A.V.3    Ochs, M.F.4
  • 25
    • 34249725570 scopus 로고    scopus 로고
    • Predictive modeling of signaling crosstalk during C. elegans vulval development
    • doi: 10.1371/journal.pcbi.0030092
    • Fisher, J., Piterman, N., Hajnal, A., and Henzinger, T. A. (2007). Predictive modeling of signaling crosstalk during C. elegans vulval development. PLoS Comput. Biol. 3:e92. doi: 10.1371/journal.pcbi.0030092
    • (2007) PLoS Comput. Biol. , vol.3
    • Fisher, J.1    Piterman, N.2    Hajnal, A.3    Henzinger, T.A.4
  • 26
    • 13844309568 scopus 로고    scopus 로고
    • Computational insights into Caenorhabditis elegans vulval development
    • doi: 10.1073/pnas.0409433102
    • Fisher, J., Piterman, N., Hubbard, E. J. A., Stern, M. J., and Harel, D. (2005). Computational insights into Caenorhabditis elegans vulval development. Proc. Natl. Acad. Sci. U.S.A. 102, 1951-1956. doi: 10.1073/pnas.0409433102
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 1951-1956
    • Fisher, J.1    Piterman, N.2    Hubbard, E.J.A.3    Stern, M.J.4    Harel, D.5
  • 27
    • 18444417998 scopus 로고    scopus 로고
    • aph-1 and pen-2 Are required for notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation
    • doi: 10.1016/S1534-5807(02)00189-2
    • Francis, R., McGrath, G., Zhang, J., Ruddy, D. A., Sym, M., Apfeld, J., et al. (2002). aph-1 and pen-2 Are required for notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation. Dev. Cell 3, 85-97. doi: 10.1016/S1534-5807(02)00189-2
    • (2002) Dev. Cell , vol.3 , pp. 85-97
    • Francis, R.1    McGrath, G.2    Zhang, J.3    Ruddy, D.A.4    Sym, M.5    Apfeld, J.6
  • 28
    • 79957615574 scopus 로고    scopus 로고
    • From binary to multivalued to continuous models: the lac operon as a case study
    • doi: 10.2390/biecoll-jib-2010-151
    • Franke, R., Theis, F. J., and Klamt, S. (2010). From binary to multivalued to continuous models: the lac operon as a case study. J. Integr. Bioinform. 7, 151. doi: 10.2390/biecoll-jib-2010-151
    • (2010) J. Integr. Bioinform. , vol.7 , pp. 151
    • Franke, R.1    Theis, F.J.2    Klamt, S.3
  • 29
    • 31944451493 scopus 로고    scopus 로고
    • Intercellular coupling amplifies fate segregation during Caenorhabditis elegans vulval development
    • doi: 10.1073/pnas.0506476103
    • Giurumescu, C. A., Sternberg, P. W., and Asthagiri, A. R. (2006). Intercellular coupling amplifies fate segregation during Caenorhabditis elegans vulval development. Proc. Natl. Acad. Sci. U.S.A. 103, 1331-1336. doi: 10.1073/pnas.0506476103
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , pp. 1331-1336
    • Giurumescu, C.A.1    Sternberg, P.W.2    Asthagiri, A.R.3
  • 30
    • 66249096743 scopus 로고    scopus 로고
    • Predicting phenotypic diversity and the underlying quantitative molecular transitions
    • doi: 10.1371/journal.pcbi.1000354
    • Giurumescu, C. A., Sternberg, P. W., and Asthagiri, A. R. (2009). Predicting phenotypic diversity and the underlying quantitative molecular transitions. PLoS Comput. Biol. 5:e1000354. doi: 10.1371/journal.pcbi.1000354
    • (2009) PLoS Comput. Biol. , vol.5
    • Giurumescu, C.A.1    Sternberg, P.W.2    Asthagiri, A.R.3
  • 31
    • 0037093441 scopus 로고    scopus 로고
    • Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C
    • doi: 10.1101/gad.981602
    • Gleason, J. E., Korswagen, H. C., and Eisenmann, D. M. (2002). Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction. Genes Dev. 16, 1281-1290. doi: 10.1101/gad.981602
    • (2002) elegans vulval induction. Genes Dev. , vol.16 , pp. 1281-1290
    • Gleason, J.E.1    Korswagen, H.C.2    Eisenmann, D.M.3
  • 32
    • 33748969657 scopus 로고    scopus 로고
    • Multiple redundant Wnt signaling components function in two processes during C
    • doi: 10.1016/j.ydbio.2006.06.050
    • Gleason, J. E., Szyleyko, E. A., and Eisenmann, D. M. (2006). Multiple redundant Wnt signaling components function in two processes during C. elegans vulval development. Dev. Biol. 298, 442-457. doi: 10.1016/j.ydbio.2006.06.050
    • (2006) elegans vulval development. Dev. Biol. , vol.298 , pp. 442-457
    • Gleason, J.E.1    Szyleyko, E.A.2    Eisenmann, D.M.3
  • 34
    • 33646352954 scopus 로고    scopus 로고
    • GINsim: a software suite for the qualitative modelling, simulation and analysis of regulatory networks
    • doi: 10.1016/j.biosystems.2005.10.003
    • Gonzalez, A. G., Naldi, A., Sanchez, L., Thieffry, D., and Chaouiya, C. (2006). GINsim: a software suite for the qualitative modelling, simulation and analysis of regulatory networks. Biosystems 84, 91-100. doi: 10.1016/j.biosystems.2005.10.003
    • (2006) Biosystems , vol.84 , pp. 91-100
    • Gonzalez, A.G.1    Naldi, A.2    Sanchez, L.3    Thieffry, D.4    Chaouiya, C.5
  • 35
    • 0034080403 scopus 로고    scopus 로고
    • aph-2 encodes a novel extracellular protein required for GLP-1-mediated signaling
    • Goutte, C., Hepler, W., Mickey, K. M., and Priess, J. R. (2000). aph-2 encodes a novel extracellular protein required for GLP-1-mediated signaling. Development 127, 2481-2492.
    • (2000) Development , vol.127 , pp. 2481-2492
    • Goutte, C.1    Hepler, W.2    Mickey, K.M.3    Priess, J.R.4
  • 36
    • 0037154158 scopus 로고    scopus 로고
    • APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos
    • doi: 10.1073/pnas.022523499
    • Goutte, C., Tsunozaki, M., Hale, V. A., and Priess, J. R. (2002). APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos. Proc. Natl. Acad. Sci. U.S.A. 99, 775-779. doi: 10.1073/pnas.022523499
    • (2002) Proc. Natl. Acad. Sci. U.S.A. , vol.99 , pp. 775-779
    • Goutte, C.1    Tsunozaki, M.2    Hale, V.A.3    Priess, J.R.4
  • 38
    • 49549106034 scopus 로고    scopus 로고
    • Opposing Wnt pathways orient cell polarity during organogenesis
    • doi: 10.1016/j.cell.2008.06.026
    • Green, J. L., Inoue, T., and Sternberg, P. W. (2008). Opposing Wnt pathways orient cell polarity during organogenesis. Cell 134, 646-656. doi: 10.1016/j.cell.2008.06.026
    • (2008) Cell , vol.134 , pp. 646-656
    • Green, J.L.1    Inoue, T.2    Sternberg, P.W.3
  • 40
    • 0020827717 scopus 로고
    • The lin-12 locus specifies cell fates in caenorhabditis elegans
    • doi: 10.1016/0092-8674(83)90377-X
    • Greenwald, I. S., Sternberg, P. W., and Horvitz, H. R. (1983). The lin-12 locus specifies cell fates in caenorhabditis elegans. Cell 34, 435-444. doi: 10.1016/0092-8674(83)90377-X
    • (1983) Cell , vol.34 , pp. 435-444
    • Greenwald, I.S.1    Sternberg, P.W.2    Horvitz, H.R.3
  • 41
    • 0042913254 scopus 로고    scopus 로고
    • The C. elegans LIM homeobox gene lin-11 specifies multiple cell fates during vulval development
    • Gupta, B. P., Wang, M., and Sternberg, P. W. (2003). The C. elegans LIM homeobox gene lin-11 specifies multiple cell fates during vulval development. Development 130, 2589-2601.
    • (2003) Development , vol.130 , pp. 2589-2601
    • Gupta, B.P.1    Wang, M.2    Sternberg, P.W.3
  • 42
    • 0030774790 scopus 로고    scopus 로고
    • Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinase
    • doi: 10.1242/dev.00500
    • Hajnal, A., Whitfield, C. W., and Kim, S. K. (1997). Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinase. Genes Dev. 11, 2715-2728. doi: 10.1242/dev.00500
    • (1997) Genes Dev. , vol.11 , pp. 2715-2728
    • Hajnal, A.1    Whitfield, C.W.2    Kim, S.K.3
  • 43
    • 0025647293 scopus 로고
    • The let-60 locus controls the switch between vulval and nonvulval cell fates in Caenorhabditis elegans
    • doi: 10.1101/gad.11.20.2715
    • Han, M., Aroian, R. V., and Sternberg, P. W. (1990). The let-60 locus controls the switch between vulval and nonvulval cell fates in Caenorhabditis elegans. Genetics 126, 899-913. doi: 10.1101/gad.11.20.2715
    • (1990) Genetics , vol.126 , pp. 899-913
    • Han, M.1    Aroian, R.V.2    Sternberg, P.W.3
  • 44
    • 0027263251 scopus 로고
    • C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation
    • doi: 10.1038/363133a0
    • Han, M., Golden, A., Han, Y., and Sternberg, P. W. (1993). C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation. Nature 363, 133-140. doi: 10.1038/363133a0
    • (1993) Nature , vol.363 , pp. 133-140
    • Han, M.1    Golden, A.2    Han, Y.3    Sternberg, P.W.4
  • 46
    • 38449103236 scopus 로고    scopus 로고
    • Hermaphrodite cell-fate specification. WormBook, ed The C. elegans Research Community
    • WormBook. doi: 10.1895/wormbook.1.39.1
    • Herman, M. A. (2006). Hermaphrodite cell-fate specification. WormBook, ed The C. elegans Research Community, WormBook. doi: 10.1895/wormbook.1.39.1
    • (2006)
    • Herman, M.A.1
  • 47
    • 0026763373 scopus 로고
    • The gene lin-3 encodes an inductive signal for vulval development in C
    • doi: 10.1038/358470a0
    • Hill, R. J., and Sternberg, P. W. (1992). The gene lin-3 encodes an inductive signal for vulval development in C. elegans. Nature 358, 470-476. doi: 10.1038/358470a0
    • (1992) elegans. Nature , vol.358 , pp. 470-476
    • Hill, R.J.1    Sternberg, P.W.2
  • 49
    • 33947533569 scopus 로고    scopus 로고
    • Introduction to genetics and genomics. WormBook, ed The C. elegans Research Community
    • WormBook. doi: 10.1895/wormbook.1.17.1
    • Hodgkin, J. (2005). Introduction to genetics and genomics. WormBook, ed The C. elegans Research Community, WormBook. doi: 10.1895/wormbook.1.17.1
    • (2005)
    • Hodgkin, J.1
  • 50
    • 0034175594 scopus 로고    scopus 로고
    • The Caenorhabditis elegans APC-related gene apr-1 is required for epithelial cell migration and Hox gene expression
    • Hoier, E. F., Mohler, W. A., Kim, S. K., and Hajnal, A. (2000). The Caenorhabditis elegans APC-related gene apr-1 is required for epithelial cell migration and Hox gene expression. Genes Dev 14, 874-886.
    • (2000) Genes Dev , vol.14 , pp. 874-886
    • Hoier, E.F.1    Mohler, W.A.2    Kim, S.K.3    Hajnal, A.4
  • 52
    • 79953768697 scopus 로고    scopus 로고
    • Quantitative variation in autocrine signaling and pathway crosstalk in the Caenorhabditis vulva network
    • doi: 10.1016/j.cub.2011.02.040
    • Hoyos, E., Kim, K., Milloz, J., Barkoulas, M., Pénigault, J.-B., Munro, E., et al. (2011). Quantitative variation in autocrine signaling and pathway crosstalk in the Caenorhabditis vulva network. Curr. Biol. 21, 527-538. doi: 10.1016/j.cub.2011.02.040
    • (2011) Curr. Biol. , vol.21 , pp. 527-538
    • Hoyos, E.1    Kim, K.2    Milloz, J.3    Barkoulas, M.4    Pénigault, J.-B.5    Munro, E.6
  • 53
    • 0036188791 scopus 로고    scopus 로고
    • Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates
    • Hsu, V., Zobel, C. L., Lambie, E. J., Schedl, T., and Kornfeld, K. (2002). Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates. Genetics 160, 481-492.
    • (2002) Genetics , vol.160 , pp. 481-492
    • Hsu, V.1    Zobel, C.L.2    Lambie, E.J.3    Schedl, T.4    Kornfeld, K.5
  • 54
    • 4544329969 scopus 로고    scopus 로고
    • C. elegans LIN-18 is a ryk ortholog and functions in parallel to LIN-17/frizzled in wnt signaling
    • doi: 10.1016/j.cell.2004.09.001
    • Inoue, T., Oz, H. S., Wiland, D., Gharib, S., Deshpande, R., Hill, R. J., et al. (2004). C. elegans LIN-18 is a ryk ortholog and functions in parallel to LIN-17/frizzled in wnt signaling. Cell 118, 795-806. doi: 10.1016/j.cell.2004.09.001
    • (2004) Cell , vol.118 , pp. 795-806
    • Inoue, T.1    Oz, H.S.2    Wiland, D.3    Gharib, S.4    Deshpande, R.5    Hill, R.J.6
  • 55
    • 0031904310 scopus 로고    scopus 로고
    • Gain-of-function mutations in the Caenorhabditis elegans lin-1 ETS gene identify a C-terminal regulatory domain phosphorylated by ERK MAP kinase
    • Jacobs, D., Beitel, G. J., Clark, S. G., Horvitz, H. R., and Kornfeld, K. (1998). Gain-of-function mutations in the Caenorhabditis elegans lin-1 ETS gene identify a C-terminal regulatory domain phosphorylated by ERK MAP kinase. Genetics 149, 1809-1822.
    • (1998) Genetics , vol.149 , pp. 1809-1822
    • Jacobs, D.1    Beitel, G.J.2    Clark, S.G.3    Horvitz, H.R.4    Kornfeld, K.5
  • 57
    • 0032544565 scopus 로고    scopus 로고
    • The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C
    • doi: 10.1016/S0092-8674(00)81735-3
    • Kaech, S. M., Whitfield, C. W., and Kim, S. K. (1998). The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells. Cell 94, 761-771. doi: 10.1016/S0092-8674(00)81735-3
    • (1998) elegans EGF receptor LET-23 in vulval epithelial cells. Cell , vol.94 , pp. 761-771
    • Kaech, S.M.1    Whitfield, C.W.2    Kim, S.K.3
  • 58
    • 0030773708 scopus 로고    scopus 로고
    • Binary specification of the embryonic lineage in Caenorhabditis elegans
    • doi: 10.1038/36869
    • Kaletta, T., Schnabel, H., and Schnabel, R. (1997). Binary specification of the embryonic lineage in Caenorhabditis elegans. Nature 390, 294-298. doi: 10.1038/36869
    • (1997) Nature , vol.390 , pp. 294-298
    • Kaletta, T.1    Schnabel, H.2    Schnabel, R.3
  • 60
    • 53849108096 scopus 로고    scopus 로고
    • A scenario-based approach to modeling development: a prototype model of C. elegans vulval fate specification
    • doi: 10.1016/j.ydbio.2008.07.030
    • Kam, N., Kugler, H., Marelly, R., Appleby, L., Fisher, J., Pnueli, A., et al. (2008). A scenario-based approach to modeling development: a prototype model of C. elegans vulval fate specification. Dev. Biol. 323, 1-5. doi: 10.1016/j.ydbio.2008.07.030
    • (2008) Dev. Biol. , vol.323 , pp. 1-5
    • Kam, N.1    Kugler, H.2    Marelly, R.3    Appleby, L.4    Fisher, J.5    Pnueli, A.6
  • 62
    • 0030026887 scopus 로고    scopus 로고
    • A point mutation in the extracellular domain activates LET-23, the Caenorhabditis elegans epidermal growth factor receptor homolog
    • Katz, W. S., Lesa, G. M., Yannoukakos, D., Clandinin, T. R., Schlessinger, J., and Sternberg, P. W. (1996). A point mutation in the extracellular domain activates LET-23, the Caenorhabditis elegans epidermal growth factor receptor homolog. Mol. Cell. Biol. 16, 529-537.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 529-537
    • Katz, W.S.1    Lesa, G.M.2    Yannoukakos, D.3    Clandinin, T.R.4    Schlessinger, J.5    Sternberg, P.W.6
  • 63
    • 0014489272 scopus 로고
    • Metabolic stability and epigenesis in randomly constructed genetic nets
    • doi: 10.1016/0022-5193(69)90015-0
    • Kauffman, S. A. (1969). Metabolic stability and epigenesis in randomly constructed genetic nets. J. Theor. Biol. 22, 437-467. doi: 10.1016/0022-5193(69)90015-0
    • (1969) J. Theor. Biol. , vol.22 , pp. 437-467
    • Kauffman, S.A.1
  • 64
    • 0003694798 scopus 로고
    • The Origins of Order: Self-Organization and Selection in Evolution. 1st Edn.
    • New York, NY: Oxford University Press
    • Kauffman, S. A. (1993). The Origins of Order: Self-Organization and Selection in Evolution. 1st Edn. New York, NY: Oxford University Press.
    • (1993)
    • Kauffman, S.A.1
  • 65
    • 20444383880 scopus 로고    scopus 로고
    • A /beta-catenin identified by functional rather than sequence criteria and its role in wnt/MAPK signaling
    • doi: 10.1016/j.cell.2005.03.029
    • KiddIII, A. R., Miskowski, J. A., Siegfried, K. R., Sawa, H., and Kimble, J. (2005). A /beta-catenin identified by functional rather than sequence criteria and its role in wnt/MAPK signaling. Cell 121, 761-772. doi: 10.1016/j.cell.2005.03.029
    • (2005) Cell , vol.121 , pp. 761-772
    • Kidd, A.R.1    Miskowski, J.A.2    Siegfried, K.R.3    Sawa, H.4    Kimble, J.5
  • 66
    • 1242295300 scopus 로고    scopus 로고
    • The nT1 translocation separates vulval regulatory elements from the egl-18 and elt-6 GATA factor genes
    • doi: 10.1016/j.ydbio.2003.11.014
    • Koh, K., Bernstein, Y., and Sundaram, M. V. (2004). The nT1 translocation separates vulval regulatory elements from the egl-18 and elt-6 GATA factor genes. Dev. Biol. 267, 252-263. doi: 10.1016/j.ydbio.2003.11.014
    • (2004) Dev. Biol. , vol.267 , pp. 252-263
    • Koh, K.1    Bernstein, Y.2    Sundaram, M.V.3
  • 67
    • 18744404224 scopus 로고    scopus 로고
    • Cell fates and fusion in the C. elegans vulval primordium are regulated by the EGL-18 and ELT-6 GATA factors - apparent direct targets of the LIN-39 Hox protein
    • Koh, K., Peyrot, S. M., Wood, C. G., Wagmaister, J. A., Maduro, M. F., Eisenmann, D. M., et al. (2002). Cell fates and fusion in the C. elegans vulval primordium are regulated by the EGL-18 and ELT-6 GATA factors - apparent direct targets of the LIN-39 Hox protein. Development 129, 5171-5180.
    • (2002) Development , vol.129 , pp. 5171-5180
    • Koh, K.1    Peyrot, S.M.2    Wood, C.G.3    Wagmaister, J.A.4    Maduro, M.F.5    Eisenmann, D.M.6
  • 68
    • 0037093399 scopus 로고    scopus 로고
    • The Axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C
    • doi: 10.1101/gad.981802
    • Korswagen, H. C., Coudreuse, D. Y., Betist, M. C., van de Water, S., Zivkovic, D., and Clevers, H. C. (2002). The Axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans. Genes Dev. 16, 1291-1302. doi: 10.1101/gad.981802
    • (2002) elegans. Genes Dev. , vol.16 , pp. 1291-1302
    • Korswagen, H.C.1    Coudreuse, D.Y.2    Betist, M.C.3    van de Water, S.4    Zivkovic, D.5    Clevers, H.C.6
  • 69
    • 0031717482 scopus 로고    scopus 로고
    • Genetic analysis of the Caenorhabditis elegans MAP kinase gene mpk-1
    • Lackner, M. R., and Kim, S. K. (1998). Genetic analysis of the Caenorhabditis elegans MAP kinase gene mpk-1. Genetics 150, 103-117.
    • (1998) Genetics , vol.150 , pp. 103-117
    • Lackner, M.R.1    Kim, S.K.2
  • 70
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • doi: 10.1016/0092-8674(93)90529-Y
    • Lee, R. C., Feinbaum, R. L., and Ambros, V. (1993). The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854. doi: 10.1016/0092-8674(93)90529-Y
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 71
    • 0035894534 scopus 로고    scopus 로고
    • APH-2/nicastrin functions in LIN-12/notch signaling in the Caenorhabditis elegans somatic gonad
    • doi: 10.1006/dbio.2001.0486
    • Levitan, D., Yu, G., Hyslop, P. S. G., and Goutte, C. (2001). APH-2/nicastrin functions in LIN-12/notch signaling in the Caenorhabditis elegans somatic gonad. Dev. Biol. 240, 654-661. doi: 10.1006/dbio.2001.0486
    • (2001) Dev. Biol. , vol.240 , pp. 654-661
    • Levitan, D.1    Yu, G.2    Hyslop, P.S.G.3    Goutte, C.4
  • 72
    • 67651062669 scopus 로고    scopus 로고
    • Simulation-based model checking approach to cell fate specification during Caenorhabditis elegans vulval development by hybrid functional Petri net with extension
    • doi: 10.1186/1752-0509-3-42
    • Li, C., Nagasaki, M., Ueno, K., and Miyano, S. (2009). Simulation-based model checking approach to cell fate specification during Caenorhabditis elegans vulval development by hybrid functional Petri net with extension. BMC Syst. Biol. 3:42. doi: 10.1186/1752-0509-3-42
    • (2009) BMC Syst. Biol. , vol.3 , pp. 42
    • Li, C.1    Nagasaki, M.2    Ueno, K.3    Miyano, S.4
  • 73
    • 78049241052 scopus 로고    scopus 로고
    • LIN-14 inhibition of LIN-12 contributes to precision and timing of C
    • doi: 10.1016/j.cub.2010.09.055
    • Li, J., and Greenwald, I. (2010). LIN-14 inhibition of LIN-12 contributes to precision and timing of C. elegans vulval fate patterning. Curr. Biol. 20, 1875-1879. doi: 10.1016/j.cub.2010.09.055
    • (2010) elegans vulval fate patterning. Curr. Biol. , vol.20 , pp. 1875-1879
    • Li, J.1    Greenwald, I.2
  • 74
    • 0028783457 scopus 로고
    • pop-l Encodes an HMG box protein required for the specification of a mesoderm precursor in early C
    • doi: 10.1016/0092-8674(95)90100-0
    • Lin, R., Thompso, S., and Priess, J. R. (1995). pop-l Encodes an HMG box protein required for the specification of a mesoderm precursor in early C. elegans embryos. Cell 83, 599-609. doi: 10.1016/0092-8674(95)90100-0
    • (1995) elegans embryos. Cell , vol.83 , pp. 599-609
    • Lin, R.1    Thompso, S.2    Priess, J.R.3
  • 75
    • 79955778578 scopus 로고    scopus 로고
    • Reproductive system, egglaying apparatus
    • doi: 10.3908/wormatlas.1.24
    • Lints, R., and Hall, D. (2009). "Reproductive system, egglaying apparatus," in WormAtlas. doi: 10.3908/wormatlas.1.24
    • (2009) in WormAtlas
    • Lints, R.1    Hall, D.2
  • 76
    • 1842715734 scopus 로고    scopus 로고
    • Phosphorylation by the β-catenin/MAPK complex promotes 14-3-3-mediated nuclear export of TCF/POP-1 in signal-responsive cells in C
    • doi: 10.1016/S0092-8674(04)00203-X
    • Lo, M.-C., Gay, F., Odom, R., Shi, Y., and Lin, R. (2004). Phosphorylation by the β-catenin/MAPK complex promotes 14-3-3-mediated nuclear export of TCF/POP-1 in signal-responsive cells in C. elegans. Cell 117, 95-106. doi: 10.1016/S0092-8674(04)00203-X
    • (2004) elegans. Cell , vol.117 , pp. 95-106
    • Lo, M.-C.1    Gay, F.2    Odom, R.3    Shi, Y.4    Lin, R.5
  • 78
    • 33646345600 scopus 로고    scopus 로고
    • A network model for the control of the differentiation process in Th cells
    • doi: 10.1016/j.biosystems.2005.10.004
    • Mendoza, L. (2006). A network model for the control of the differentiation process in Th cells. Biosystems 84, 101-114. doi: 10.1016/j.biosystems.2005.10.004
    • (2006) Biosystems , vol.84 , pp. 101-114
    • Mendoza, L.1
  • 79
    • 0034530133 scopus 로고    scopus 로고
    • Null mutations in the lin-31 gene indicate two functions during Caenorhabditis elegans vulval development
    • Miller, L. M., Hess, H. A., Doroquez, D. B., and Andrews, N. M. (2000). Null mutations in the lin-31 gene indicate two functions during Caenorhabditis elegans vulval development. Genetics 156, 1595-1602.
    • (2000) Genetics , vol.156 , pp. 1595-1602
    • Miller, L.M.1    Hess, H.A.2    Doroquez, D.B.3    Andrews, N.M.4
  • 80
    • 38049170535 scopus 로고    scopus 로고
    • Wnt signal from multiple tissues and lin-3/EGF signal from the gonad maintain vulval precursor cell competence in Caenorhabditis elegans
    • doi: 10.1073/pnas.0709989104
    • Myers, T. R., and Greenwald, I. (2007). Wnt signal from multiple tissues and lin-3/EGF signal from the gonad maintain vulval precursor cell competence in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 104, 20368-20373. doi: 10.1073/pnas.0709989104
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 20368-20373
    • Myers, T.R.1    Greenwald, I.2
  • 81
    • 0032414178 scopus 로고    scopus 로고
    • Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates
    • Nilsson, L., Li, X., Tiensuu, T., Auty, R., Greenwald, I., and Tuck, S. (1998). Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates. Development 125, 4809-4819.
    • (1998) Development , vol.125 , pp. 4809-4819
    • Nilsson, L.1    Li, X.2    Tiensuu, T.3    Auty, R.4    Greenwald, I.5    Tuck, S.6
  • 82
    • 0037022533 scopus 로고    scopus 로고
    • C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation
    • doi: 10.1016/S0960-9822(02)00690-5
    • Ohmachi, M., Rocheleau, C. E., Church, D., Lambie, E., Schedl, T., and Sundaram, M. V. (2002). C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation. Curr. Biol. 12, 427-433. doi: 10.1016/S0960-9822(02)00690-5
    • (2002) Curr. Biol. , vol.12 , pp. 427-433
    • Ohmachi, M.1    Rocheleau, C.E.2    Church, D.3    Lambie, E.4    Schedl, T.5    Sundaram, M.V.6
  • 83
    • 34547697748 scopus 로고    scopus 로고
    • Two functionally distinct Axin-like proteins regulate canonical Wnt signaling in C
    • doi: 10.1016/j.ydbio.2007.05.043
    • Oosterveen, T., Coudreuse, D. Y., Yang, P.-T., Fraser, E., Bergsma, J., Dale, T. C., et al. (2007). Two functionally distinct Axin-like proteins regulate canonical Wnt signaling in C. elegans. Dev. Biol. 308, 438-448. doi: 10.1016/j.ydbio.2007.05.043
    • (2007) elegans. Dev. Biol. , vol.308 , pp. 438-448
    • Oosterveen, T.1    Coudreuse, D.Y.2    Yang, P.-T.3    Fraser, E.4    Bergsma, J.5    Dale, T.C.6
  • 84
    • 11144340990 scopus 로고    scopus 로고
    • C. elegans MOM-5/Frizzled functions in MOM-2/Wnt-independent cell polarity and is localized asymmetrically prior to cell division
    • doi: 10.1016/j.cub.2004.12.019
    • Park, F. D., Tenlen, J. R., and Priess, J. R. (2005). C. elegans MOM-5/Frizzled functions in MOM-2/Wnt-independent cell polarity and is localized asymmetrically prior to cell division. Curr. Biol. 14, 2252-2258. doi: 10.1016/j.cub.2004.12.019
    • (2005) Curr. Biol. , vol.14 , pp. 2252-2258
    • Park, F.D.1    Tenlen, J.R.2    Priess, J.R.3
  • 85
    • 80052181678 scopus 로고    scopus 로고
    • Evolution of a system sensitive to stochastic noise: P3.p cell fate in Caenorhabditis.
    • doi: 10.1016/j.ydbio.2011.05.675
    • Pénigault, J.-B., and Félix, M.-A. (2011a). Evolution of a system sensitive to stochastic noise: P3.p cell fate in Caenorhabditis. Dev. Biol. 357, 419-427. doi: 10.1016/j.ydbio.2011.05.675
    • (2011) Dev. Biol. , vol.357 , pp. 419-427
    • Pénigault, J.-B.1    Félix, M.-A.2
  • 87
    • 0034682337 scopus 로고    scopus 로고
    • Lag-3 is a putative transcriptional activator in the C
    • doi: 10.1038/35012645
    • Petcherski, A. G., and Kimble, J. (2000). Lag-3 is a putative transcriptional activator in the C. elegans notch pathway. Nature 405, 364-368. doi: 10.1038/35012645
    • (2000) elegans notch pathway. Nature , vol.405 , pp. 364-368
    • Petcherski, A.G.1    Kimble, J.2
  • 88
    • 0033598401 scopus 로고    scopus 로고
    • Casein kinase i transduces Wnt signals
    • doi: 10.1038/43830
    • Peters, J. M., McKay, R. M., McKay, J. P., and Graff, J. M. (1999). Casein kinase i transduces Wnt signals. Nature 401, 345-350. doi: 10.1038/43830
    • (1999) Nature , vol.401 , pp. 345-350
    • Peters, J.M.1    McKay, R.M.2    McKay, J.P.3    Graff, J.M.4
  • 89
    • 33847688427 scopus 로고    scopus 로고
    • Reciprocal asymmetry of SYS-1//beta-catenin and POP-1/TCF controls asymmetric divisions in Caenorhabditis elegans
    • doi: 10.1073/pnas.0611507104
    • Phillips, B. T., III, Kidd, A. R., King, R., Hardin, J., and Kimble, J. (2007). Reciprocal asymmetry of SYS-1//beta-catenin and POP-1/TCF controls asymmetric divisions in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 104, 3231-3236. doi: 10.1073/pnas.0611507104
    • (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 3231-3236
    • Phillips, B.T.1    Kidd, A.R.2    King, R.3    Hardin, J.4    Kimble, J.5
  • 90
    • 38449085266 scopus 로고    scopus 로고
    • Cell fusion. WormBook, ed The C. elegans Research Community
    • WormBook. doi: 10.1895/wormbook.1.52.1
    • Podbilewicz, B. (2006). Cell fusion. WormBook, ed The C. elegans Research Community, WormBook. doi: 10.1895/wormbook.1.52.1
    • (2006)
    • Podbilewicz, B.1
  • 91
    • 33748942475 scopus 로고    scopus 로고
    • The C. elegans developmental fusogen EFF-1 mediates homotypic fusion in heterologous cells and in vivo
    • doi: 10.1016/j.devcel.2006.09.004
    • Podbilewicz, B., Leikina, E., Sapir, A., Valansi, C., Suissa, M., Shemer, G., et al. (2006). The C. elegans developmental fusogen EFF-1 mediates homotypic fusion in heterologous cells and in vivo. Dev. Cell 11, 471-481. doi: 10.1016/j.devcel.2006.09.004
    • (2006) Dev. Cell , vol.11 , pp. 471-481
    • Podbilewicz, B.1    Leikina, E.2    Sapir, A.3    Valansi, C.4    Suissa, M.5    Shemer, G.6
  • 92
    • 41649092673 scopus 로고    scopus 로고
    • Notch signaling and morphogenesis of single-cell tubes in the C
    • doi: 10.1016/j.devcel.2008.01.019
    • Rasmussen, J. P., English, K., Tenlen, J., and Priess, J. R. (2008). Notch signaling and morphogenesis of single-cell tubes in the C. elegans digestive tract. Dev. Cell 14, 559-569. doi: 10.1016/j.devcel.2008.01.019
    • (2008) elegans digestive tract. Dev. Cell , vol.14 , pp. 559-569
    • Rasmussen, J.P.1    English, K.2    Tenlen, J.3    Priess, J.R.4
  • 93
    • 0037083988 scopus 로고    scopus 로고
    • KSR is a scaffold required for activation of the ERK/MAPK module
    • doi: 10.1101/gad.962902
    • Roy, F., Laberge, G., Douziech, M., Ferland-McCollough, D., and Therrien, M. (2002). KSR is a scaffold required for activation of the ERK/MAPK module. Genes Dev. 16, 427-438. doi: 10.1101/gad.962902
    • (2002) Genes Dev. , vol.16 , pp. 427-438
    • Roy, F.1    Laberge, G.2    Douziech, M.3    Ferland-McCollough, D.4    Therrien, M.5
  • 94
    • 61449309306 scopus 로고    scopus 로고
    • Segmenting the fly embryo: logical analysis of the role of the Segment Polarity cross-regulatory module
    • doi: 10.1387/ijdb.072439ls
    • Sánchez, L., Chaouia, C., and Thieffry, D. (2008). Segmenting the fly embryo: logical analysis of the role of the Segment Polarity cross-regulatory module. Int. J. Dev. Biol. 52, 1059-1075. doi: 10.1387/ijdb.072439ls
    • (2008) Int. J. Dev. Biol. , vol.52 , pp. 1059-1075
    • Sánchez, L.1    Chaouia, C.2    Thieffry, D.3
  • 95
    • 0029814396 scopus 로고    scopus 로고
    • The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein, similar to the Drosophila Frizzled protein
    • doi: 10.1101/gad.10.17.2189
    • Sawa, H., Lobel, L., and Horvitz, H. R. (1996). The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein, similar to the Drosophila Frizzled protein. Genes Dev. 10, 2189-2197. doi: 10.1101/gad.10.17.2189
    • (1996) Genes Dev. , vol.10 , pp. 2189-2197
    • Sawa, H.1    Lobel, L.2    Horvitz, H.R.3
  • 97
    • 0034644539 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • doi: 10.1016/S0092-8674(00)00114-8
    • Schlessinger, J. (2000). Cell signaling by receptor tyrosine kinases. Cell 103, 211-225. doi: 10.1016/S0092-8674(00)00114-8
    • (2000) Cell , vol.103 , pp. 211-225
    • Schlessinger, J.1
  • 98
    • 0033046809 scopus 로고    scopus 로고
    • Formation of the vulva in Caenorhabditis elegans: a paradigm for organogenesis
    • Sharma-Kishore, R., White, J. G., Southgate, E., and Podbilewicz, B. (1999). Formation of the vulva in Caenorhabditis elegans: a paradigm for organogenesis. Development 126, 691-699.
    • (1999) Development , vol.126 , pp. 691-699
    • Sharma-Kishore, R.1    White, J.G.2    Southgate, E.3    Podbilewicz, B.4
  • 99
    • 0037069661 scopus 로고    scopus 로고
    • Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans
    • doi: 10.1038/nature01234
    • Shaye, D. D., and Greenwald, I. (2002). Endocytosis-mediated downregulation of LIN-12/Notch upon Ras activation in Caenorhabditis elegans. Nature 420, 689-690. doi: 10.1038/nature01234
    • (2002) Nature , vol.420 , pp. 689-690
    • Shaye, D.D.1    Greenwald, I.2
  • 100
    • 28144455439 scopus 로고    scopus 로고
    • LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans
    • doi: 10.1242/dev.02076
    • Shaye, D. D., and Greenwald, I. (2005). LIN-12/Notch trafficking and regulation of DSL ligand activity during vulval induction in Caenorhabditis elegans. Development 132, 5081-5092. doi: 10.1242/dev.02076
    • (2005) Development , vol.132 , pp. 5081-5092
    • Shaye, D.D.1    Greenwald, I.2
  • 101
    • 0037115467 scopus 로고    scopus 로고
    • LIN-39/Hox triggers cell division and represses EFF-1/fusogen-dependent vulval cell fusion
    • doi: 10.1101/gad.251202
    • Shemer, G., and Podbilewicz, B. (2002). LIN-39/Hox triggers cell division and represses EFF-1/fusogen-dependent vulval cell fusion. Genes Dev. 16, 3136-3141. doi: 10.1101/gad.251202
    • (2002) Genes Dev. , vol.16 , pp. 3136-3141
    • Shemer, G.1    Podbilewicz, B.2
  • 102
    • 4644367201 scopus 로고    scopus 로고
    • EFF-1 is sufficient to initiate and execute tissue-specific cell fusion in C. elegans
    • doi: 10.1016/j.cub.2004.07.059
    • Shemer, G., Suissa, M., Kolotuev, I., Nguyen, K. C., Hall, D. H., and Podbilewicz, B. (2004). EFF-1 is sufficient to initiate and execute tissue-specific cell fusion in C. elegans. Curr. Biol. 14, 1587-1591. doi: 10.1016/j.cub.2004.07.059
    • (2004) Curr. Biol. , vol.14 , pp. 1587-1591
    • Shemer, G.1    Suissa, M.2    Kolotuev, I.3    Nguyen, K.C.4    Hall, D.H.5    Podbilewicz, B.6
  • 103
    • 0036333273 scopus 로고    scopus 로고
    • Pop-1 controls axis formation during early gonadogenesis in C
    • Siegfried, K. R., and Kimble, J. (2002). Pop-1 controls axis formation during early gonadogenesis in C. elegans. Development 129, 443-453.
    • (2002) elegans. Development , vol.129 , pp. 443-453
    • Siegfried, K.R.1    Kimble, J.2
  • 104
    • 0029993728 scopus 로고    scopus 로고
    • Let-23 receptor localization by the cell junction protein LIN-7 during C
    • doi: 10.1016/S0092-8674(00)81096-X
    • Simske, J. S., Kaech, S. M., Harp, S. A., and Kim, S. K. (1996). Let-23 receptor localization by the cell junction protein LIN-7 during C. elegans vulval induction. Cell 85, 195-204. doi: 10.1016/S0092-8674(00)81096-X
    • (1996) elegans vulval induction. Cell , vol.85 , pp. 195-204
    • Simske, J.S.1    Kaech, S.M.2    Harp, S.A.3    Kim, S.K.4
  • 105
    • 0029160169 scopus 로고
    • sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction
    • doi: 10.1101/gad.9.18.2251
    • Singh, N., and Han, M. (1995). sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction. Genes Dev. 9, 2251-2265. doi: 10.1101/gad.9.18.2251
    • (1995) Genes Dev. , vol.9 , pp. 2251-2265
    • Singh, N.1    Han, M.2
  • 106
    • 33751333097 scopus 로고    scopus 로고
    • Vulval development. WormBook, ed The C. elegans Research Community
    • WormBook. doi: 10.1895/wormbook.1.6.1
    • Sternberg, P. W. (2005). Vulval development. WormBook, ed The C. elegans Research Community, WormBook. doi: 10.1895/wormbook.1.6.1
    • (2005)
    • Sternberg, P.W.1
  • 107
    • 0022500775 scopus 로고
    • Pattern formation during vulval development in C
    • doi: 10.1016/0092-8674(86)90842-1
    • Sternberg, P. W., and Horvitz, H. (1986). Pattern formation during vulval development in C. elegans. Cell 44, 761-772. doi: 10.1016/0092-8674(86)90842-1
    • (1986) elegans. Cell , vol.44 , pp. 761-772
    • Sternberg, P.W.1    Horvitz, H.2
  • 108
    • 0024309272 scopus 로고
    • The combined action of two intercellular signaling pathways specifies three cell fates during vulval induction in C
    • doi: 10.1016/0092-8674(89)90103-7
    • Sternberg, P. W., and Horvitz, H. (1989). The combined action of two intercellular signaling pathways specifies three cell fates during vulval induction in C. elegans. Cell 58, 679-693. doi: 10.1016/0092-8674(89)90103-7
    • (1989) elegans. Cell , vol.58 , pp. 679-693
    • Sternberg, P.W.1    Horvitz, H.2
  • 109
    • 34547852231 scopus 로고    scopus 로고
    • Computational modeling of Caenorhabditis elegans vulval induction
    • doi: 10.1093/bioinformatics/btm214
    • Sun, X., and Hong, P. (2007). Computational modeling of Caenorhabditis elegans vulval induction. Bioinformatics 23, i499-i507. doi: 10.1093/bioinformatics/btm214
    • (2007) Bioinformatics , vol.23
    • Sun, X.1    Hong, P.2
  • 111
    • 33846781480 scopus 로고    scopus 로고
    • Transcriptional control of Notch signaling by a HOX and a PBX/EXD protein during vulval development in C
    • doi: 10.1016/j.ydbio.2006.09.049
    • Takács-Vellai, K., Vellai, T., Chenc, E. B., Zhang, Y., Guerry, F., Stern, M. J., et al. (2007). Transcriptional control of Notch signaling by a HOX and a PBX/EXD protein during vulval development in C. elegans. Dev. Biol. 302, 661-669. doi: 10.1016/j.ydbio.2006.09.049
    • (2007) elegans. Dev. Biol. , vol.302 , pp. 661-669
    • Takács-Vellai, K.1    Vellai, T.2    Chenc, E.B.3    Zhang, Y.4    Guerry, F.5    Stern, M.J.6
  • 112
    • 23744516722 scopus 로고    scopus 로고
    • Asymmetric cortical and nuclear localizations of WRM-1//beta-catenin during asymmetric cell division in C
    • doi: 10.1101/gad.1322805
    • Takeshita, H., and Sawa, H. (2005). Asymmetric cortical and nuclear localizations of WRM-1//beta-catenin during asymmetric cell division in C. elegans. Genes Dev. 19, 1743-1748. doi: 10.1101/gad.1322805
    • (2005) elegans. Genes Dev. , vol.19 , pp. 1743-1748
    • Takeshita, H.1    Sawa, H.2
  • 113
    • 0032524912 scopus 로고    scopus 로고
    • MAP kinase signaling specificity mediated by the LIN-1 Ets/LIN-31 WH transcription factor complex during C
    • doi: 10.1016/S0092-8674(00)81186-1
    • Tan, P. B., Lackner, M. R., and Kim, S. K. (1998). MAP kinase signaling specificity mediated by the LIN-1 Ets/LIN-31 WH transcription factor complex during C. elegans vulval induction. Cell 93, 569-580. doi: 10.1016/S0092-8674(00)81186-1
    • (1998) elegans vulval induction. Cell , vol.93 , pp. 569-580
    • Tan, P.B.1    Lackner, M.R.2    Kim, S.K.3
  • 114
    • 25844462281 scopus 로고    scopus 로고
    • lin-1 has both positive and negative functions in specifying multiple cell fates induced by ras/MAP kinase signaling in C
    • doi: 10.1016/j.ydbio.2005.08.007
    • Tiensuu, T., Larsen, M. K., Vernersson, E., and Tuck, S. (2005). lin-1 has both positive and negative functions in specifying multiple cell fates induced by ras/MAP kinase signaling in C. elegans. Dev. Biol. 286, 338-351. doi: 10.1016/j.ydbio.2005.08.007
    • (2005) elegans. Dev. Biol. , vol.286 , pp. 338-351
    • Tiensuu, T.1    Larsen, M.K.2    Vernersson, E.3    Tuck, S.4
  • 115
    • 77954890727 scopus 로고    scopus 로고
    • The C. elegans Hox gene ceh-13 regulates cell migration and fusion in a non-colinear way. implications for the early evolution of Hox clusters
    • doi: 10.1186/1471-213X-10-78
    • Tihanyi, B., Vellai, T., Regos, Á, Ari, E., Müller, F., and Takács-Vellai, K. (2010). The C. elegans Hox gene ceh-13 regulates cell migration and fusion in a non-colinear way. implications for the early evolution of Hox clusters. BMC Dev. Biol. 10:78. doi: 10.1186/1471-213X-10-78
    • (2010) BMC Dev. Biol. , vol.10 , pp. 78
    • Tihanyi, B.1    Vellai, T.2    Regos, A.3    Ari, E.4    Müller, F.5    Takács-Vellai, K.6
  • 116
    • 0028915009 scopus 로고
    • lin-25, a gene required for vulval induction in Caenorhabditis elegans
    • doi: 10.1101/gad.9.3.341
    • Tuck, S., and Greenwald, I. (1995). lin-25, a gene required for vulval induction in Caenorhabditis elegans. Genes Dev. 9, 341-357. doi: 10.1101/gad.9.3.341
    • (1995) Genes Dev. , vol.9 , pp. 341-357
    • Tuck, S.1    Greenwald, I.2
  • 118
    • 33748450887 scopus 로고    scopus 로고
    • Identification of cis-regulatory elements from the C. elegans Hox gene lin-39 required for embryonic expression and for regulation by the transcription factors LIN-1, LIN-31 and LIN-39
    • doi: 10.1016/j.ydbio.2006.05.008
    • Wagmaister, J. A., Miley, G. R., Morris, C. A., Gleason, J. E., Miller, L. M., Kornfeld, K., et al. (2006b). Identification of cis-regulatory elements from the C. elegans Hox gene lin-39 required for embryonic expression and for regulation by the transcription factors LIN-1, LIN-31 and LIN-39. Dev. Biol. 297, 550-565. doi: 10.1016/j.ydbio.2006.05.008
    • (2006) Dev. Biol. , vol.297 , pp. 550-565
    • Wagmaister, J.A.1    Miley, G.R.2    Morris, C.A.3    Gleason, J.E.4    Miller, L.M.5    Kornfeld, K.6
  • 119
    • 33748976491 scopus 로고    scopus 로고
    • mig-5/Dsh controls cell fate determination and cell migration in C
    • doi: 10.1016/j.ydbio.2006.06.053
    • Walston, T., Guo, C., Proenca, R., Wu, M., Herman, M., Hardin, J., et al. (2006). mig-5/Dsh controls cell fate determination and cell migration in C. elegans. Dev. Biol. 298, 485-497. doi: 10.1016/j.ydbio.2006.06.053
    • (2006) elegans. Dev. Biol. , vol.298 , pp. 485-497
    • Walston, T.1    Guo, C.2    Proenca, R.3    Wu, M.4    Herman, M.5    Hardin, J.6
  • 120
    • 0033179093 scopus 로고    scopus 로고
    • Competence and commitment of Caenorhabditis elegans vulval precursor cells
    • doi: 10.1006/dbio.1999.9357
    • Wang, M., and Sternberg, P. W. (1999). Competence and commitment of Caenorhabditis elegans vulval precursor cells. Dev. Biol. 212, 12-24. doi: 10.1006/dbio.1999.9357
    • (1999) Dev. Biol. , vol.212 , pp. 12-24
    • Wang, M.1    Sternberg, P.W.2
  • 121
    • 0031470904 scopus 로고    scopus 로고
    • SUP-17, a Caenorhabditis elegans ADAM protein related to Drosophila KUZBANIAN, and its role in LIN-12/NOTCH signalling
    • Wen, C., Metzstein, M. M., and Greenwald, I. (1997). SUP-17, a Caenorhabditis elegans ADAM protein related to Drosophila KUZBANIAN, and its role in LIN-12/NOTCH signalling. Development 124, 4759-4767.
    • (1997) Development , vol.124 , pp. 4759-4767
    • Wen, C.1    Metzstein, M.M.2    Greenwald, I.3
  • 122
    • 0033514950 scopus 로고    scopus 로고
    • Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch-pathway signaling
    • doi: 10.1073/pnas.96.5.2497
    • Westlund, B., Parry, D., Clover, R., Basson, M., and Johnson, C. D. (1999). Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel-12 and hop-1 in Notch-pathway signaling. Proc. Natl. Acad. Sci. U.S.A. 96, 2497-2502. doi: 10.1073/pnas.96.5.2497
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 2497-2502
    • Westlund, B.1    Parry, D.2    Clover, R.3    Basson, M.4    Johnson, C.D.5
  • 123
    • 0028641294 scopus 로고
    • Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C
    • doi: 10.1016/0092-8674(94)90010-8
    • Wilkinson, H. A., Fitzgerald, K., and Greenwald, I. (1994). Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision. Cell 79, 1187-1198. doi: 10.1016/0092-8674(94)90010-8
    • (1994) elegans cell fate decision. Cell , vol.79 , pp. 1187-1198
    • Wilkinson, H.A.1    Fitzgerald, K.2    Greenwald, I.3
  • 124
    • 0034687874 scopus 로고    scopus 로고
    • Positive versus negative signaling of LET-23: regulation through the adaptor protein, SEM-5
    • doi: 10.1126/stke.2000.63.pe2
    • Worby, C., and Margolis, B. (2000). Positive versus negative signaling of LET-23: regulation through the adaptor protein, SEM-5. Sci. STKE 2000:pe2. doi: 10.1126/stke.2000.63.pe2
    • (2000) Sci. STKE , vol.2000
    • Worby, C.1    Margolis, B.2
  • 125
    • 0028943025 scopus 로고
    • MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events
    • doi: 10.1101/gad.9.6.742
    • Wu, Y., Han, M., and Guan, K.-L. (1995). MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events. Genes Dev. 9, 742-755. doi: 10.1101/gad.9.6.742
    • (1995) Genes Dev. , vol.9 , pp. 742-755
    • Wu, Y.1    Han, M.2    Guan, K.-L.3
  • 127
    • 0442272485 scopus 로고    scopus 로고
    • Crosstalk between the EGFR and LIN-12/notch pathways in C
    • doi: 10.1126/science.1091639
    • Yoo, A. S., Bais, C., and Greenwald, I. (2004). Crosstalk between the EGFR and LIN-12/notch pathways in C. elegans vulval development. Science 303, 663-666. doi: 10.1126/science.1091639
    • (2004) elegans vulval development. Science , vol.303 , pp. 663-666
    • Yoo, A.S.1    Bais, C.2    Greenwald, I.3
  • 128
    • 28144458897 scopus 로고    scopus 로고
    • LIN-12/Notch activation leads to microRNA-mediated down-regulation of vav in C
    • doi: 10.1126/science.1119481
    • Yoo, A. S., and Greenwald, I. (2005). LIN-12/Notch activation leads to microRNA-mediated down-regulation of vav in C. elegans. Science 310, 1330-1333. doi: 10.1126/science.1119481
    • (2005) elegans. Science , vol.310 , pp. 1330-1333
    • Yoo, A.S.1    Greenwald, I.2
  • 129
    • 70349281405 scopus 로고    scopus 로고
    • Two hox cofactors, the meis/hth homolog UNC-62 and the pbx/ exd homolog CEH-20, function together during C
    • doi: 10.1016/j.ydbio.2009.07.034
    • Yuan Jiang, H. S., and Liu, J. (2009). Two hox cofactors, the meis/hth homolog UNC-62 and the pbx/ exd homolog CEH-20, function together during C. elegans postembryonic mesodermal development. Dev. Biol. 334, 535-546. doi: 10.1016/j.ydbio.2009.07.034
    • (2009) elegans postembryonic mesodermal development. Dev. Biol. , vol.334 , pp. 535-546
    • Yuan Jiang, H.S.1    Liu, J.2
  • 130
    • 78651467570 scopus 로고    scopus 로고
    • Ras effector switching promotes divergent cell fates in c
    • doi: 10.1016/j.devcel.2010.12.004
    • Zand, T. P., Reiner, D. J., and Der, C. J. (2011). Ras effector switching promotes divergent cell fates in c. elegans vulval patterning. Dev. Cell 20, 84-96. doi: 10.1016/j.devcel.2010.12.004
    • (2011) elegans vulval patterning. Dev. Cell , vol.20 , pp. 84-96
    • Zand, T.P.1    Reiner, D.J.2    Der, C.J.3
  • 131
    • 80051498826 scopus 로고    scopus 로고
    • Spatial regulation of lag-2 transcription during vulval precursor cell fate patterning in Caenorhabditis elegans
    • doi: 10.1534/genetics.111.12838
    • Zhang, X., and Greenwald, I. (2011). Spatial regulation of lag-2 transcription during vulval precursor cell fate patterning in Caenorhabditis elegans. Genetics 188, 847-858. doi: 10.1534/genetics.111.128389
    • (2011) Genetics , vol.188 , pp. 847-858
    • Zhang, X.1    Greenwald, I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.