Novel fluorine-18 PET radiotracers based on flumazenil for GABAA imaging in the brain

Nuclear Medicine and Biology

Volumn 40, Issue 7, 2013, Pages 901-905

  Rodnick, Melissa E ^a   Hockley, Brian G ^a   Sherman, Phillip ^a   Quesada, Carole ^a   Battle, Mark R ^b   Jackson, Alexander ^b   Linder, Karen E ^c   Macholl, Sven ^b   Trigg, William J ^b   Kilbourn, Michael R ^a   Scott, Peter J H ^a,d  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b GE HEALTHCARE   (United Kingdom)

^c GE HEALTHCARE   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Benzodiazepine; Neurology; PET; Radiopharmaceutical synthesis

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; AH 114726; FLUMAZENIL C 11; FLUORINE AH 114726 F 18; FLUORINE FLUMAZENIL F 18; FLUORINE GEH 120348 F 18; GEH 120348; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG IDENTIFICATION; DRUG STRUCTURE; DRUG UPTAKE; FEMALE; IN VIVO STUDY; ISOTOPE LABELING; ISOTOPE TRACING; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RADIOASSAY; RADIOISOTOPE DISTRIBUTION; RHESUS MONKEY; TISSUE DISTRIBUTION;

BENZODIAZEPINE; NEUROLOGY; PET; RADIOPHARMACEUTICAL SYNTHESIS;

ANIMALS; BRAIN; FEMALE; FLUMAZENIL; FLUORINE RADIOISOTOPES; MACACA MULATTA; POSITRON-EMISSION TOMOGRAPHY; RADIOCHEMISTRY; RECEPTORS, GABA-A;

EID: 84883560687     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2013.06.004     Document Type: Article

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