Development of microwave-based automated nucleophilic [18F]fluorination system and its application to the production of [18F]flumazenil

Nuclear Medicine and Biology

Volumn 36, Issue 4, 2009, Pages 403-409

  Mandap, Katheryn S ^a   Ido, Tatsuo ^a,b   Kiyono, Yasushi ^a   Kobayashi, Masato ^a   Lohith, Talakad G ^a   Mori, Tetsuya ^a   Kasamatsu, Shingo ^a   Kudo, Takashi ^a   Okazawa, Hidehiko ^a   Fujibayashi, Yasuhisa ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b Japan Radioisotope Association   (Japan)

Author keywords

18F flumazenil; Central benzodiazepine receptors; Microwave; Radiofluorination

Indexed keywords

FLUMAZENIL; FLUMAZENIL F 18; FLUORINE 18; N,N DIMETHYLFORMAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; AUTOMATION; CONTROLLED STUDY; DRUG ISOLATION; DRUG MANUFACTURE; DRUG RETENTION; DRUG STABILITY; DRUG SYNTHESIS; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MICROWAVE RADIATION; NONHUMAN; RADIOCHEMISTRY; RAT;

ANIMALS; AUTOMATION; ETHANOL; FLUMAZENIL; FLUORINE RADIOISOTOPES; HALOGENATION; HOT TEMPERATURE; INJECTIONS; MALE; MICROWAVES; POSITRON-EMISSION TOMOGRAPHY; RATS; SOLUBILITY; SOLUTIONS; SOLVENTS; STAINING AND LABELING;

EID: 67349191012     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2009.01.011     Document Type: Article

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