Ligand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity

Cytokine

Volumn 64, Issue 1, 2013, Pages 286-297

  Krause, Christopher D ^a   Digioia, Gina ^a,b   Izotova, Lara S ^a   Xie, Junxia ^a   Kim, Youngsun ^a   Schwartz, Barbara J ^a   Mirochnitchenko, Olga V ^a   Pestka, Sidney ^a,b  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b Pestka Biomedical Laboratories   (United States)

Author keywords

Confocal fluorescence spectroscopy; FRET; Interferon receptor; RACK 1; Receptor reconstitution

Indexed keywords

ALPHA INTERFERON; ALPHA INTERFERON RECEPTOR; ALPHA INTERFERON RECEPTOR 1; ALPHA INTERFERON RECEPTOR 2C; GAMMA INTERFERON RECEPTOR 1; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 10 RECEPTOR 2; JANUS KINASE 1; LIGAND; RECEPTOR FOR ACTIVATED C KINASE 1; UNCLASSIFIED DRUG;

ARTICLE; CELL LINE; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENCE SPECTROSCOPY; GENETIC ENGINEERING; GENETIC TRANSFECTION; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN MODIFICATION;

CIFP; CONFOCAL FLUORESCENCE SPECTROSCOPY; ECFP; EGFP; ENHANCED CITRINE FLUORESCENT PROTEIN; ENHANCED CYAN FLUORESCENT PROTEIN; ENHANCED GREEN FLUORESCENT PROTEIN; ENHANCED YELLOW FLUORESCENT PROTEIN; EYFP; FLUORESCENCE RESONANCE ENERGY TRANSFER; FRET; IFN; IFN-Α; IFN-Γ; IFN-Λ; INTERFERON; INTERFERON RECEPTOR; INTERFERON-ALPHA; INTERFERON-GAMMA; INTERFERON-LAMBDA; OFP; ORANGE FLUORESCENT PROTEIN; RACK-1; RECEPTOR FOR ACTIVATED PROTEIN KINASE-1; RECEPTOR RECONSTITUTION; STFP; STRAWBERRY FLUORESCENT PROTEIN;

CELL LINE; FLUORESCENCE RESONANCE ENERGY TRANSFER; GTP-BINDING PROTEINS; HUMANS; INTERFERON-ALPHA; INTERFERON-GAMMA; JANUS KINASE 1; MULTIPROTEIN COMPLEXES; NEOPLASM PROTEINS; PROTEIN BINDING; RECEPTOR, INTERFERON ALPHA-BETA; RECEPTORS, CELL SURFACE; RECEPTORS, INTERFERON; TYK2 KINASE;

EID: 84883559027     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2013.06.309     Document Type: Article

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