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Volumn 4 AUG, Issue , 2013, Pages

Efficacy and tolerability of intravenous levetiracetam in children

Author keywords

Children; Epilepsy; Intractable epilepsy; Intravenous levetiracetam; Seizures; Status epilepticus

Indexed keywords

4 AMINOBUTYRIC ACID; ANTICONVULSIVE AGENT; ETIRACETAM; PHENOBARBITAL;

EID: 84883535358     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2013.00120     Document Type: Article
Times cited : (10)

References (37)
  • 1
    • 0027272387 scopus 로고
    • Recommendations of the Epilepsy Foundation of America's Working Group on Status Epilepticus
    • Treatment of convulsive status epilepticus, doi:10.1001/jama.270.7.854
    • Treatment of convulsive status epilepticus. Recommendations of the Epilepsy Foundation of America's Working Group on Status Epilepticus. JAMA (1993) 270:854-9. doi:10.1001/jama.270.7.854
    • (1993) JAMA , vol.270 , pp. 854-859
  • 2
    • 0032921086 scopus 로고    scopus 로고
    • It's time to revise the definition of status epilepticus
    • doi:10.1111/j.1528-1157.1999.tb02000.x
    • Lowenstein DH, Bleck T, Macdonald RL. It's time to revise the definition of status epilepticus. Epilepsia (1999) 40:120-2. doi:10.1111/j.1528-1157.1999.tb02000.x
    • (1999) Epilepsia , vol.40 , pp. 120-122
    • Lowenstein, D.H.1    Bleck, T.2    Macdonald, R.L.3
  • 3
    • 0029943483 scopus 로고    scopus 로고
    • Status epilepticus and acute repetitive seizures in children, adolescents, and young adults: etiology, outcome and treatment
    • doi:10.1111/j.1528-1157.1996.tb06025.x
    • Mitchell WG. Status epilepticus and acute repetitive seizures in children, adolescents, and young adults: etiology, outcome and treatment. Epilepsia (1996) 37(Suppl l):S74-80. doi:10.1111/j.1528-1157.1996.tb06025.x
    • (1996) Epilepsia , vol.37 , Issue.SUPPL L
    • Mitchell, W.G.1
  • 4
    • 3042748137 scopus 로고    scopus 로고
    • The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam
    • doi:10.1073/pnas.0308208101
    • Lynch B, Lambeng N, Nocka K, Kensel-Hammes P, Baijalieh SM, Matagne A, et al. The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci U S A (2004) 101:9861-6. doi:10.1073/pnas.0308208101
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 9861-9866
    • Lynch, B.1    Lambeng, N.2    Nocka, K.3    Kensel-Hammes, P.4    Baijalieh, S.M.5    Matagne, A.6
  • 5
    • 33746115639 scopus 로고    scopus 로고
    • Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study
    • doi:10.1111/j.1528-1167.2006.00586.x
    • Ramael S, Daoust A, Otoul C, Toublanc N, Troenaru M, Lu ZS, et al. Levetiracetam intravenous infusion: a randomized, placebo-controlled safety and pharmacokinetic study. Epilepsia (2006) 47:1128-35. doi:10.1111/j.1528-1167.2006.00586.x
    • (2006) Epilepsia , vol.47 , pp. 1128-1135
    • Ramael, S.1    Daoust, A.2    Otoul, C.3    Toublanc, N.4    Troenaru, M.5    Lu, Z.S.6
  • 6
    • 33745974941 scopus 로고    scopus 로고
    • Single-dose bioavailability of levetiracetam intravenous infusion relative to oral tablets and multiple-dose pharmacokinetics and tolerability of levetiracetam intravenous infusion compared with placebo in healthy subjects
    • doi:10.1016/j.clinthera.2006.05.004
    • Ramael S, De Smedt F, Toublanc N, Otoul C, Boulanger P, Riethuisen JM, et al. Single-dose bioavailability of levetiracetam intravenous infusion relative to oral tablets and multiple-dose pharmacokinetics and tolerability of levetiracetam intravenous infusion compared with placebo in healthy subjects. Clin Ther (2006) 28:734-44. doi:10.1016/j.clinthera.2006.05.004
    • (2006) Clin Ther , vol.28 , pp. 734-744
    • Ramael, S.1    De Smedt, F.2    Toublanc, N.3    Otoul, C.4    Boulanger, P.5    Riethuisen, J.M.6
  • 7
    • 84883540852 scopus 로고    scopus 로고
    • Prospective open-label, single-arm, multicenter, safety, tolerability, and pharmacokinetic studies of Intravenous levetiracetam in children with epilepsy
    • [Epub ahead of print]. doi:10.1177/0883073813480241
    • Weinstock A, Ruiz M, Gerard D, Toublanc N, Stockis A, Farooq O, et al. Prospective open-label, single-arm, multicenter, safety, tolerability, and pharmacokinetic studies of Intravenous levetiracetam in children with epilepsy. J Child Neurol (2013). [Epub ahead of print]. doi:10.1177/0883073813480241
    • (2013) J Child Neurol
    • Weinstock, A.1    Ruiz, M.2    Gerard, D.3    Toublanc, N.4    Stockis, A.5    Farooq, O.6
  • 8
    • 0032563178 scopus 로고    scopus 로고
    • Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy
    • doi:10.1016/S0014-2999(98)00410-5
    • Klitgaard H, Matagne A, Gobert J, Wülfert E. Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy. Eur J Pharmacol (1998) 353:191-206. doi:10.1016/S0014-2999(98)00410-5
    • (1998) Eur J Pharmacol , vol.353 , pp. 191-206
    • Klitgaard, H.1    Matagne, A.2    Gobert, J.3    Wülfert, E.4
  • 9
    • 2142818536 scopus 로고    scopus 로고
    • Anticonvulsant effects of levetiracetam and levetiracetam-diazepam combinations in experimental status epilepticus
    • doi:10.1016/j.eplepsyres.2004.02.002
    • Mazarati AM, Baldwin R, Klitgaard H, Matagne A, Wasterlain CG. Anticonvulsant effects of levetiracetam and levetiracetam-diazepam combinations in experimental status epilepticus. Epilepsy Res (2004) 58:167-74. doi:10.1016/j.eplepsyres.2004.02.002
    • (2004) Epilepsy Res , vol.58 , pp. 167-174
    • Mazarati, A.M.1    Baldwin, R.2    Klitgaard, H.3    Matagne, A.4    Wasterlain, C.G.5
  • 10
    • 33847625508 scopus 로고    scopus 로고
    • Levetiracetam intravenous infusion as an alternative to oral dosing in patients with partial-onset seizures
    • doi:10.1111/j.1528-1167.2006.00959.x
    • Baulac M, Brodie MJ, Elger CE, Krakow K, Stockis A, Mewisch P, et al. Levetiracetam intravenous infusion as an alternative to oral dosing in patients with partial-onset seizures. Epilepsia (2007) 48:589-92. doi:10.1111/j.1528-1167.2006.00959.x
    • (2007) Epilepsia , vol.48 , pp. 589-592
    • Baulac, M.1    Brodie, M.J.2    Elger, C.E.3    Krakow, K.4    Stockis, A.5    Mewisch, P.6
  • 11
    • 84882769269 scopus 로고    scopus 로고
    • Neonatal seizures
    • doi:10.1542/neo.13-4-e213
    • Olson DM. Neonatal seizures. Neoreviews (2012) 13:e213-23. doi:10.1542/neo.13-4-e213
    • (2012) Neoreviews , vol.13
    • Olson, D.M.1
  • 12
    • 59749103891 scopus 로고    scopus 로고
    • Neonatal seizures: do they damage the brain?
    • doi:10.1016/j.pediatrneurol.2008.10.026
    • Thibeault-Eybalin MP, Lortie A, Carmant L. Neonatal seizures: do they damage the brain? Pediatr Neurol (2009) 40:175-80. doi:10.1016/j.pediatrneurol.2008.10.026
    • (2009) Pediatr Neurol , vol.40 , pp. 175-180
    • Thibeault-Eybalin, M.P.1    Lortie, A.2    Carmant, L.3
  • 13
    • 0032912953 scopus 로고    scopus 로고
    • The epidemiology of clinical neonatal seizures in Newfoundland: a population-based study
    • doi:10.1016/S0022-3476(99)70374-4
    • Ronen GM, Penney S, Andrews W. The epidemiology of clinical neonatal seizures in Newfoundland: a population-based study. J Pediatr (1999) 134:71-5. doi:10.1016/S0022-3476(99)70374-4
    • (1999) J Pediatr , vol.134 , pp. 71-75
    • Ronen, G.M.1    Penney, S.2    Andrews, W.3
  • 14
    • 77955982977 scopus 로고    scopus 로고
    • Synergistic neuroprotective therapies in hypothermia
    • doi:10.1016/j.siny.2010.02.002
    • Cilio MR, Ferriero DM. Synergistic neuroprotective therapies in hypothermia. Semin Fetal Neonatal Med (2010) 15:293-8. doi:10.1016/j.siny.2010.02.002
    • (2010) Semin Fetal Neonatal Med , vol.15 , pp. 293-298
    • Cilio, M.R.1    Ferriero, D.M.2
  • 15
    • 47049102489 scopus 로고    scopus 로고
    • Off-label use of antiepileptic drugs for the treatment of neonatal seizures
    • doi:10.1016/j.pediatrneurol.2008.04.008
    • Silverstein FS, Ferriero DM. Off-label use of antiepileptic drugs for the treatment of neonatal seizures. Pediatr Neurol (2008) 39:77-9. doi:10.1016/j.pediatrneurol.2008.04.008
    • (2008) Pediatr Neurol , vol.39 , pp. 77-79
    • Silverstein, F.S.1    Ferriero, D.M.2
  • 16
    • 84876109190 scopus 로고    scopus 로고
    • The effect of levetiracetam on neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury
    • doi:10.1016/j.earlhumdev.2012.12.002
    • Kilicdag H, Daglioglu K, Erdogan S, Guzel A, Sencar L, Polat S, et al. The effect of levetiracetam on neuronal apoptosis in neonatal rat model of hypoxic ischemic brain injury. Early Hum Dev (2013) 89:355-60. doi:10.1016/j.earlhumdev.2012.12.002
    • (2013) Early Hum Dev , vol.89 , pp. 355-360
    • Kilicdag, H.1    Daglioglu, K.2    Erdogan, S.3    Guzel, A.4    Sencar, L.5    Polat, S.6
  • 17
    • 83555164586 scopus 로고    scopus 로고
    • Treating neonates with levetiracetam: a survey among German University Hospitals
    • doi:10.1055/s-0031-1287822
    • Koppelstäetter A, Buhrer C, Kaindl AM. Treating neonates with levetiracetam: a survey among German University Hospitals. Klin Padiatr (2011) 223:450-2. doi:10.1055/s-0031-1287822
    • (2011) Klin Padiatr , vol.223 , pp. 450-452
    • Koppelstäetter, A.1    Buhrer, C.2    Kaindl, A.M.3
  • 18
    • 0033549786 scopus 로고    scopus 로고
    • Phenobarbital compared with phenytoin for the treatment of neonatal seizures
    • doi:10.1056/NEJM199908123410704
    • Painter MJ, Scher MS, Stein AD, Armatti S, Wang Z, Gardiner JC, et al. Phenobarbital compared with phenytoin for the treatment of neonatal seizures. N Engl J Med (1999) 341:485-9. doi:10.1056/NEJM199908123410704
    • (1999) N Engl J Med , vol.341 , pp. 485-489
    • Painter, M.J.1    Scher, M.S.2    Stein, A.D.3    Armatti, S.4    Wang, Z.5    Gardiner, J.C.6
  • 20
    • 79952549970 scopus 로고    scopus 로고
    • Use of intravenous levetiracetam for management of acute seizures in neonates
    • doi:10.1016/j.pediatrneurol.2010.11.005
    • Khan O, Chang E, Cipriani C, Wright C, Crisp E, Kirmani B. Use of intravenous levetiracetam for management of acute seizures in neonates. Pediatr Neurol (2011) 44:265-9. doi:10.1016/j.pediatrneurol.2010.11.005
    • (2011) Pediatr Neurol , vol.44 , pp. 265-269
    • Khan, O.1    Chang, E.2    Cipriani, C.3    Wright, C.4    Crisp, E.5    Kirmani, B.6
  • 21
    • 34249852186 scopus 로고    scopus 로고
    • Levetiracetam for the treatment of neonatal seizures
    • doi:10.1177/0883073807299973
    • Shoemaker MT, Rotenberg JS. Levetiracetam for the treatment of neonatal seizures. J Child Neurol (2007) 22:95-8. doi:10.1177/0883073807299973
    • (2007) J Child Neurol , vol.22 , pp. 95-98
    • Shoemaker, M.T.1    Rotenberg, J.S.2
  • 22
    • 29244451059 scopus 로고    scopus 로고
    • Levetiracetam in a neonate with malignant migrating partial seizures
    • doi:10.1016/j.pediatrneurol.2005.06.011
    • Hmaimess G, Kadhim H, Nassogne MC, Bonnier C, van Rijckevorsel K. Levetiracetam in a neonate with malignant migrating partial seizures. Pediatr Neurol (2006) 34:55-9. doi:10.1016/j.pediatrneurol.2005.06.011
    • (2006) Pediatr Neurol , vol.34 , pp. 55-59
    • Hmaimess, G.1    Kadhim, H.2    Nassogne, M.C.3    Bonnier, C.4    van Rijckevorsel, K.5
  • 23
    • 71649092881 scopus 로고    scopus 로고
    • Levetiracetam as mono-therapy for seizures in a neonate with acute lymphoblastic leukemia
    • doi:10.1016/j.ejpn.2008.12.007
    • Ledet DS, Wheless JW, Rubnitz JE, Brannon Morris E. Levetiracetam as mono-therapy for seizures in a neonate with acute lymphoblastic leukemia. Eur J Paediatr Neurol (2010) 14:78-9. doi:10.1016/j.ejpn.2008.12.007
    • (2010) Eur J Paediatr Neurol , vol.14 , pp. 78-79
    • Ledet, D.S.1    Wheless, J.W.2    Rubnitz, J.E.3    Brannon Morris, E.4
  • 24
    • 77549083859 scopus 로고    scopus 로고
    • Levetiracetam in the treatment of neonatal seizures: a pilot study
    • doi:10.1016/j.seizure.2010.01.003
    • Furwentsches A, Bussman C, Ramantani G, Ebinger F, Philippi H, Poschl J, et al. Levetiracetam in the treatment of neonatal seizures: a pilot study. Seizure (2010) 19:185-9. doi:10.1016/j.seizure.2010.01.003
    • (2010) Seizure , vol.19 , pp. 185-189
    • Furwentsches, A.1    Bussman, C.2    Ramantani, G.3    Ebinger, F.4    Philippi, H.5    Poschl, J.6
  • 25
  • 26
    • 79958740704 scopus 로고    scopus 로고
    • Pharmacokinetics of levetiracetam in neonates with seizures
    • doi:10.1016/j.jpeds.2011.03.057
    • Merhar SL, Schibler KR, Sherwin CM, Meinzen-Derr J, Shi J, Balmakund T, et al. Pharmacokinetics of levetiracetam in neonates with seizures. J Pediatr (2011) 159:152-4. doi:10.1016/j.jpeds.2011.03.057
    • (2011) J Pediatr , vol.159 , pp. 152-154
    • Merhar, S.L.1    Schibler, K.R.2    Sherwin, C.M.3    Meinzen-Derr, J.4    Shi, J.5    Balmakund, T.6
  • 27
    • 68749115013 scopus 로고    scopus 로고
    • Intravenous levetiracetam terminates refractory status epilepticus in two patients with migrating partial seizures in infancy
    • doi:10.1016/j.eplepsyres.2009.05.004
    • Cilio MR, Bianchi R, Balestri M, Onofri A, Giovannini S, Di Capua M, et al. Intravenous levetiracetam terminates refractory status epilepticus in two patients with migrating partial seizures in infancy. Epilepsy Res (2009) 86:66-71. doi:10.1016/j.eplepsyres.2009.05.004
    • (2009) Epilepsy Res , vol.86 , pp. 66-71
    • Cilio, M.R.1    Bianchi, R.2    Balestri, M.3    Onofri, A.4    Giovannini, S.5    Di Capua, M.6
  • 28
    • 53249090387 scopus 로고    scopus 로고
    • Tolerability and dosing experience of intravenous levetiracetam in children and infants
    • doi:10.1016/j.eplepsyres.2008.05.004
    • Michaelides C, Thibert RL, Shapiro MJ, Kinirons P, John T, Manchharama D, et al. Tolerability and dosing experience of intravenous levetiracetam in children and infants. Epilepsy Res (2008) 81:143-7. doi:10.1016/j.eplepsyres.2008.05.004
    • (2008) Epilepsy Res , vol.81 , pp. 143-147
    • Michaelides, C.1    Thibert, R.L.2    Shapiro, M.J.3    Kinirons, P.4    John, T.5    Manchharama, D.6
  • 29
    • 38949184571 scopus 로고    scopus 로고
    • Intravenous levetiracetam in children with epilepsy
    • doi:10.1016/j.pediatrneurol.2007.11.003
    • Goraya JS, Khurana DS, Valencia I, Melvin JJ, Cruz M, Legido A, et al. Intravenous levetiracetam in children with epilepsy. Pediatr Neurol (2008) 38:177-80. doi:10.1016/j.pediatrneurol.2007.11.003
    • (2008) Pediatr Neurol , vol.38 , pp. 177-1780
    • Goraya, J.S.1    Khurana, D.S.2    Valencia, I.3    Melvin, J.J.4    Cruz, M.5    Legido, A.6
  • 31
    • 39049124749 scopus 로고    scopus 로고
    • The use of levetiracetam in a child with nonconvulsive status epilepticus
    • doi:10.1177/0883073807309237
    • Alehan F, Ozcay F, Haberal M. The use of levetiracetam in a child with nonconvulsive status epilepticus. J Child Neurol (2008) 23:331-3. doi:10.1177/0883073807309237
    • (2008) J Child Neurol , vol.23 , pp. 331-333
    • Alehan, F.1    Ozcay, F.2    Haberal, M.3
  • 32
    • 77649265413 scopus 로고    scopus 로고
    • Levetiracetam in nonconvulsive status epilepticus in a child with Angelman syndrome
    • doi:10.1177/0883073809338626
    • Weber P. Levetiracetam in nonconvulsive status epilepticus in a child with Angelman syndrome. J Child Neurol (2010) 25:393-6. doi:10.1177/0883073809338626
    • (2010) J Child Neurol , vol.25 , pp. 393-396
    • Weber, P.1
  • 33
    • 66349133603 scopus 로고    scopus 로고
    • Role of intravenous levetiracetam in acute seizure management of children
    • doi:10.1016/j.pediatrneurol.2009.02.016
    • Kirmani BF, Crisp ED, Kayani S, Rajab H. Role of intravenous levetiracetam in acute seizure management of children. Pediatr Neurol (2009) 41:37-9. doi:10.1016/j.pediatrneurol.2009.02.016
    • (2009) Pediatr Neurol , vol.41 , pp. 37-39
    • Kirmani, B.F.1    Crisp, E.D.2    Kayani, S.3    Rajab, H.4
  • 34
    • 66749161081 scopus 로고    scopus 로고
    • Intravenous levetiracetam in critically ill children with status epilepticus or acute repetitive seizures
    • doi:10.1097/PCC.0b013e3181a0e1cf
    • Abend NS, Monk HM, Licht DJ, Dlugos DJ. Intravenous levetiracetam in critically ill children with status epilepticus or acute repetitive seizures. Pediatr Crit Care Med (2009) 10:505-10. doi:10.1097/PCC.0b013e3181a0e1cf
    • (2009) Pediatr Crit Care Med , vol.10 , pp. 505-510
    • Abend, N.S.1    Monk, H.M.2    Licht, D.J.3    Dlugos, D.J.4
  • 35
    • 34247161430 scopus 로고    scopus 로고
    • Levetiracetam monotherapy in children with epilepsy
    • doi:10.1016/j.pediatrneurol.2006.09.018
    • Khurana DS, Kothare SV, Valencia I, Melvin JJ, Legido A. Levetiracetam monotherapy in children with epilepsy. Pediatr Neurol (2007) 36:227-30. doi:10.1016/j.pediatrneurol.2006.09.018
    • (2007) Pediatr Neurol , vol.36 , pp. 227-230
    • Khurana, D.S.1    Kothare, S.V.2    Valencia, I.3    Melvin, J.J.4    Legido, A.5
  • 36
    • 58149154641 scopus 로고    scopus 로고
    • Levetiracetam in children with refractory status epilepticus
    • doi:10.1016/j.yebeh.2008.09.028
    • Gallentine WB, Hunnicutt AS, Husain AM. Levetiracetam in children with refractory status epilepticus. Epilepsy Behav (2009) 14:215-8. doi:10.1016/j.yebeh.2008.09.028
    • (2009) Epilepsy Behav , vol.14 , pp. 215-218
    • Gallentine, W.B.1    Hunnicutt, A.S..2    Husain, A.M.3
  • 37
    • 78751604631 scopus 로고    scopus 로고
    • Efficacy and tolerability of levetiracetam in children with epilepsy
    • doi:10.1016/j.braindev.2010.03.002
    • Li J, Xiao N, Chen S. Efficacy and tolerability of levetiracetam in children with epilepsy. Brain Dev (2011) 33:145-51. doi:10.1016/j.braindev.2010.03.002
    • (2011) Brain Dev , vol.33 , pp. 145-151
    • Li, J.1    Xiao, N.2    Chen, S.3


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