Synaptic acetylcholinesterase targeted by microRNA-212 functions as a tumor suppressor in non-small cell lung cancer

International Journal of Biochemistry and Cell Biology

Volumn 45, Issue 11, 2013, Pages 2530-2540

  Zhang, Xuejun ^a   Lu, Lu ^a   Zhang, Xuejin ^a   Zhang, Bo ^a   Wu, Jun ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Acetylcholinesterase; Apoptosis; MiR 212; Non small cell lung cancer; Tumor suppressor

Indexed keywords

ACETYLCHOLINESTERASE; CISPLATIN; MESSENGER RNA; MICRORNA; MICRORNA 212; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; MIRN212 MICRORNA, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL DEATH; CELL MEMBRANE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; ENDOPLASMIC RETICULUM; GENE REPRESSION; GENE SILENCING; GLYCOSYLATION; IN VITRO STUDY; LUNG NON SMALL CELL CANCER; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN TARGETING; RNA INTERFERENCE; TUMOR GROWTH; TUMOR XENOGRAFT; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CELL PROLIFERATION; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LUNG TUMOR; METABOLISM; MOLECULAR GENETICS; NON SMALL CELL LUNG CANCER; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PATHOLOGY; SYNAPSE; TUMOR CELL LINE;

MUS MUSCULUS;

ACETYLCHOLINESTERASE; ANIMALS; APOPTOSIS; BASE SEQUENCE; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CISPLATIN; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; MOLECULAR SEQUENCE DATA; SYNAPSES; TUMOR SUPPRESSOR PROTEINS;

EID: 84883516854     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2013.08.007     Document Type: Article

References (46)

1. C.C. Bernardi, S. Ribeiro Ede, I.J. Cavalli, E.A. Chautard-Freire-Maia, and R.L. Souza Amplification and deletion of the ACHE and BCHE cholinesterase genes in sporadic breast cancer Cancer Genetics and Cytogenetics 197 2010 158 165
2. A. Berson, M. Knobloch, M. Hanan, S. Diamant, M. Sharoni, and D. Schuppli Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology Brain: A Journal of Neurology 131 2008 109 119
3. K. Brocklehurst, A.J. Courey, S. Gul, S.H. Lin, and R.L. Moritz Lectin-agarose affinity chromatography CSH Protocols 2006 2006
4. A.M. Cheng, M.W. Byrom, J. Shelton, and L.P. Ford Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis Nucleic Acids Research 33 2005 1290 1297 (Pubitemid 41439922)
5. B.A. Coleman, and P. Taylor Regulation of acetylcholinesterase expression during neuronal differentiation The Journal of Biological Chemistry 271 1996 4410 4416 (Pubitemid 26070549)
6. R.M. Drayton, and J.W. Catto Molecular mechanisms of cisplatin resistance in bladder cancer Expert Review of Anticancer Therapy 12 2012 271 281
7. M. Fabbri, R. Garzon, A. Cimmino, Z. Liu, N. Zanesi, and E. Callegari MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B Proceedings of the National Academy of Sciences of the United States of America 104 2007 15805 15810 (Pubitemid 350035380)
8. R. Fang, T. Xiao, Z. Fang, Y. Sun, F. Li, and Y. Gao MicroRNA-143 (miR-143) regulates cancer glycolysis via targeting hexokinase 2 gene The Journal of Biological Chemistry 287 2012 23227 23235
9. J. Ferlay, H.R. Shin, F. Bray, D. Forman, C. Mathers, and D.M. Parkin Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008 International Journal of Cancer 127 2010 2893 2917
10. N.A. Franken, H.M. Rodermond, J. Stap, J. Haveman, and C. van Bree Clonogenic assay of cells in vitro Nature Protocols 1 2006 2315 2319
11. S.M. Johnson, H. Grosshans, J. Shingara, M. Byrom, R. Jarvis, and A. Cheng RAS is regulated by the let-7 microRNA family Cell 120 2005 635 647 (Pubitemid 40343076)
12. X. Karp, and V. Ambros Developmental biology. Encountering microRNAs in cell fate signaling Science 310 2005 1288 1289 (Pubitemid 41698853)
13. B. Koberle, M.T. Tomicic, S. Usanova, and B. Kaina Cisplatin resistance: preclinical findings and clinical implications Biochimica et Biophysica Acta 1806 2010 172 182
14. P. Martinez-Moreno, S. Nieto-Ceron, J. Torres-Lanzas, F. Ruiz-Espejo, I. Tovar-Zapata, and P. Martinez-Hernandez Cholinesterase activity of human lung tumours varies according to their histological classification Carcinogenesis 27 2006 429 436 (Pubitemid 43372872)
15. J.R. Molina, P. Yang, S.D. Cassivi, S.E. Schild, and A.A. Adjei Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship Mayo Clinic Proceedings 83 2008 584 594 (Pubitemid 351720831)
16. M.F. Montenegro, F. Ruiz-Espejo, F.J. Campoy, E. Munoz-Delgado, M.P. de la Cadena, and F.J. Rodriguez-Berrocal Cholinesterases are down-expressed in human colorectal carcinoma Cellular and Molecular Life Sciences 63 2006 2175 2182 (Pubitemid 44465690)
17. E. Munoz-Delgado, M.F. Montenegro, F.J. Campoy, M.T. Moral-Naranjo, J. Cabezas-Herrera, and G. Kovacs Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types The FEBS Journal 277 2010 4519 4529
18. G.J. Nuovo In situ detection of microRNAs in paraffin embedded, formalin fixed tissues and the co-localization of their putative targets Methods 52 2010 307 315
19. N.G. Ordonez The immunohistochemical diagnosis of mesothelioma: a comparative study of epithelioid mesothelioma and lung adenocarcinoma The American Journal of Surgical Pathology 27 2003 1031 1051 (Pubitemid 36909525)
20. S.E. Park, N.D. Kim, and Y.H. Yoo Acetylcholinesterase plays a pivotal role in apoptosome formation Cancer Research 64 2004 2652 2655 (Pubitemid 38500595)
21. D. Raben, B. Helfrich, D.C. Chan, F. Ciardiello, L. Zhao, and W. Franklin The effects of cetuximab alone and in combination with radiation and/or chemotherapy in lung cancer Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 11 2005 795 805 (Pubitemid 40116908)
22. C. Riccardi, and I. Nicoletti Analysis of apoptosis by propidium iodide staining and flow cytometry Nature Protocols 1 2006 1458 1461
23. F. Ruiz-Espejo, J. Cabezas-Herrera, J. Illana, F.J. Campoy, and C.J. Vidal Cholinesterase activity and acetylcholinesterase glycosylation are altered in human breast cancer Breast Cancer Research and Treatment 72 2002 11 22 (Pubitemid 34274311)
24. M. Seike, A. Goto, T. Okano, E.D. Bowman, A.J. Schetter, and I. Horikawa MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers Proceedings of the National Academy of Sciences of the United States of America 106 2009 12085 12090
25. I. Shaked, A. Meerson, Y. Wolf, R. Avni, D. Greenberg, and A. Gilboa-Geffen MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase Immunity 31 2009 965 973
26. I. Silman, and J.L. Sussman Acetylcholinesterase: 'classical' and 'non-classical' functions and pharmacology Current Opinion in Pharmacology 5 2005 293 302 (Pubitemid 40674253)
27. P. Song, H.S. Sekhon, X.W. Fu, M. Maier, Y. Jia, and J. Duan Activated cholinergic signaling provides a target in squamous cell lung carcinoma Cancer Research 68 2008 4693 4700
28. H. Soreq, and S. Seidman Acetylcholinesterase - new roles for an old actor Nature Reviews Neuroscience 2 2001 294 302 (Pubitemid 33673070)
29. J. Stephenson, B. Czepulkowski, W. Hirst, and G.J. Mufti Deletion of the acetylcholinesterase locus at 7q22 associated with myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML) Leukemia Research 20 1996 235 241 (Pubitemid 26144140)
30. M. Sternfeld, S. Shoham, O. Klein, C. Flores-Flores, T. Evron, and G.H. Idelson Excess "read-through" acetylcholinesterase attenuates but the "synaptic" variant intensifies neurodeterioration correlates Proceedings of the National Academy of Sciences of the United States of America 97 2000 8647 8652 (Pubitemid 30639727)
31. M. Syed, C. Fenoglio-Preiser, K.A. Skau, and G.F. Weber Acetylcholinesterase supports anchorage independence in colon cancer Clinical & Experimental Metastasis 25 2008 787 798
32. F. Tang, P. Hajkova, S.C. Barton, K. Lao, and M.A. Surani MicroRNA expression profiling of single whole embryonic stem cells Nucleic Acids Research 34 2006 e9
33. D. Toiber, A. Berson, D. Greenberg, N. Melamed-Book, S. Diamant, and H. Soreq N-Acetylcholinesterase-induced apoptosis in Alzheimer's disease PloS One 3 2008 e3108
34. C.J. Vidal Expression of cholinesterases in brain and non-brain tumours Chemico-Biological Interactions 157-158 2005 227 232 (Pubitemid 41757655)
35. S. Volinia, G.A. Calin, C.G. Liu, S. Ambs, A. Cimmino, and F. Petrocca A microRNA expression signature of human solid tumors defines cancer gene targets Proceedings of the National Academy of Sciences of the United States of America 103 2006 2257 2261 (Pubitemid 43271657)
36. Q. Wang, S. Wang, H. Wang, P. Li, and Z. Ma MicroRNAs: novel biomarkers for lung cancer diagnosis, prediction and treatment Experimental Biology and Medicine 237 2012 227 235
37. A. Woods, S.R. Johnstone, K. Dickerson, F.C. Leiper, L.G. Fryer, and D. Neumann LKB1 is the upstream kinase in the AMP-activated protein kinase cascade Current Biology 13 2003 2004 2008 (Pubitemid 37425212)
38. J. Xie, H. Jiang, Y.H. Wan, A.Y. Du, K.J. Guo, and T. Liu Induction of a 55 kDa acetylcholinesterase protein during apoptosis and its negative regulation by the Akt pathway Journal of Molecular Cell Biology 3 2011 250 259
39. N. Yanaihara, N. Caplen, E. Bowman, M. Seike, K. Kumamoto, and M. Yi Unique microRNA molecular profiles in lung cancer diagnosis and prognosis Cancer Cell 9 2006 189 198 (Pubitemid 43357945)
40. W. Ye, X. Gong, J. Xie, J. Wu, X. Zhang, and Q. Ouyang AChE deficiency or inhibition decreases apoptosis and p53 expression and protects renal function after ischemia/reperfusion Apoptosis: An International Journal on Programmed Cell Death 15 2010 474 487
41. H. Zakut, G. Ehrlich, A. Ayalon, C.A. Prody, G. Malinger, and S. Seidman Acetylcholinesterase and butyrylcholinesterase genes coamplify in primary ovarian carcinomas The Journal of Clinical Investigation 86 1990 900 908 (Pubitemid 20327382)
42. X. Zhang, L. Lu, S. Liu, W. Ye, J. Wu, and X. Zhang Acetylcholinesterase deficiency decreases apoptosis in dopaminergic neurons in the neurotoxin model of Parkinson's disease The International Journal of Biochemistry & Cell Biology 45 2013 265 272
43. X.J. Zhang, L. Yang, Q. Zhao, J.P. Caen, H.Y. He, and Q.H. Jin Induction of acetylcholinesterase expression during apoptosis in various cell types Cell Death and Differentiation 9 2002 790 800
44. Y. Zhao, X. Wang, T. Wang, X. Hu, X. Hui, and M. Yan Acetylcholinesterase, a key prognostic predictor for hepatocellular carcinoma, suppresses cell growth and induces chemosensitization Hepatology 53 2011 493 503
45. S. Zhu, H. Wu, F. Wu, D. Nie, S. Sheng, and Y.Y. Mo MicroRNA-21 targets tumor suppressor genes in invasion and metastasis Cell Research 18 2008 350 359 (Pubitemid 351333899)
46. S. Zochbauer-Muller, A.F. Gazdar, and J.D. Minna Molecular pathogenesis of lung cancer Annual Review of Physiology 64 2002 681 708 (Pubitemid 34259246)