Differential PARP cleavage: An indication of heterogeneous forms of cell death and involvement of multiple proteases in the infarct of focal cerebral ischemia in rat

Cellular and Molecular Neurobiology

Volumn 29, Issue 4, 2009, Pages 563-573

  Chaitanya, Ganta Vijay ^a   Babu, Phanithi Prakash ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

AIF; Apoptosis; Cerebral ischemia; Granzyme b; Necrosis; PARP

Indexed keywords

APOPTOSIS INDUCING FACTOR; CALPAIN; CASPASE 3; CATHEPSIN B; GRANZYME B; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CELL DEATH; CELL HETEROGENEITY; CONTROLLED STUDY; DENSITOMETRY; ENZYME ACTIVATION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; RAT; STAINING; TRANSIENT ISCHEMIC ATTACK; WESTERN BLOTTING;

ANIMALS; APOPTOSIS INDUCING FACTOR; BRAIN; BRAIN ISCHEMIA; CALPAIN; CASPASES; CATHEPSIN B; CELL DEATH; CEREBRAL INFARCTION; GRANZYMES; MALE; NEUROPSYCHOLOGICAL TESTS; PEPTIDE HYDROLASES; POLY(ADP-RIBOSE) POLYMERASES; RANDOM ALLOCATION; RATS; RATS, WISTAR;

RATTUS;

EID: 67449128454     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-009-9348-8     Document Type: Article

References (43)

1. M Artal-Sanz 2006 Lysosomal biogenesis and function is critical for necrotic cell death in Caenorhabditis elegans J Cell Biol 173 231 239 10.1083/jcb.200511103
2. AK Bhuyan 2001 Resting membrane potential as a marker of apoptosis: studies on Xenopus oocytes microinjected with cytochrome c Cell Death Differ 8 63 69 10.1038/sj.cdd.4400773
3. GV Chaitanya PP Babu 2008 Activation of calpain, cathepsin-b and caspase-3 during transient focal cerebral ischemia in rat model Neurochem Res 33 2178 2186
4. BB Cho LH Toledo-Pereyra 2008 Caspase-independent programmed cell death following ischemic stroke J Invest Surg 21 141 147 10.1080/08941930802029945
5. VL Dawson TM Dawson 2004 Deadly conversations: nuclear-mitochondrial cross-talk J Bioenerg Biomembr 36 287 294 10.1023/B:JOBB.0000041755.22613.8d
6. G De Murcia J Menissier de Murcia 1994 Poly (ADP-ribose) polymerase: a molecular nick-sensor Trends Biochem Sci 19 172 176 10.1016/0968-0004(94)90280-1
7. I Ferrer AM Planas 2003 Signaling of cell death and cell survival following focal cerebral ischemia: life and death struggle in the penumbra J Neuropathol Exp Neurol 62 329 339 (Pubitemid 36403033)
8. CJ Froelich 1996 Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly (ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment Biochem Biophys Res Commun 23 658 665 10.1006/bbrc.1996.1565
9. S Gobeil 2001 Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases Cell Death Differ 8 588 594 10.1038/sj.cdd.4400851
10. SH Graham J Chen 2001 Programmed cell death in cerebral ischemia J Cereb Blood Flow Metab 21 99 109 10.1097/00004647-200102000-00001 (Pubitemid 32143971)
11. HC Ha SH Snyder 1999 Poly (ADP-ribose) polymerase is a mediator of necrotic cell death by ATP depletion Proc Natl Acad Sci USA 96 13978 13982 10.1073/pnas.96.24.13978
12. PO Hassa MO Hottiger 2002 The functional role of poly (ADP-ribose) polymerase 1 as novel coactivator of NF-kappaB in inflammatory disorders Cell Mol Life Sci 59 1534 1553 10.1007/s00018-002-8527-2
13. A Haunstetter S Izumo 1998 Apoptosis: basic mechanisms and implications for cardiovascular disease Circ Res 82 1111 1129 (Pubitemid 28311120)
14. T Hayashi K Abe 2004 Ischemic neuronal cell death and organellae damage Neurol Res 26 827 834 10.1179/016164104X3770
15. Z Herzeg ZQ Wang 2001 Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death Mutat Res 477 97 110 10.1016/S0027-5107(01)00111-7
16. PD Hurn 2007 T and B cell deficient mice with experimental stroke have reduced lesion size and inflammation J Cereb Blood Flow Metab 27 1798 1805 10.1038/sj.jcbfm.9600482
17. Y Ikeda 2005 Neuroprotective effects of KCL-440, a new poly(ADP-ribose) polymerase inhibitor, in the rat middle cerebral artery occlusion model Brain Res 1060 73 80 10.1016/j.brainres.2005.08.046
18. M Kato 2000 Caspases cleaves the amino-terminal calpain inhibitory unit of calpastatin during apoptosis in human jurkat T cells J Biochem 127 297 305 (Pubitemid 30136913)
19. S Kawamura 1991 Rat middle cerebral artery occlusion using an intraluminal thread technique Acta Neurochir (Wien) 109 126 132 10.1007/BF01403007
20. SH Koh 2004 The effect of PARP inhibitor on ischaemic cell death, its related inflammation and survival signals Eur J Neurosci 20 1461 1472 10.1111/j.1460-9568.2004.03632.x
21. K Lomgren 2001 Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathologic apoptosis" J Biol Chem 276 10191 10198 10.1074/jbc.M007807200
22. EZ Longa 1989 Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 84 91 (Pubitemid 19040218)
23. SL Mehta 2007 Molecular targets in cerebral ischemia for developing novel therapeutics Brain Res Brain Res Rev 54 1 34 66 10.1016/j.brainresrev.2006.11. 003
24. K Murakami 1998 Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency J Neurosci 18 205 213 (Pubitemid 28046782)
25. RW Neumar 2003 Cross talk between Calpain and Caspase proteolytic systems during neuronal apoptosis J Biol Chem 16 1462 1467
26. P Nicotera 1998 Intracellular ATP, a switch in the decision between apoptosis and necrosis Toxicol Lett 102-103 139 142 10.1016/S0378-4274(98)00298- 7
27. AR O'Connell CC Stenson 2007 A more serine way to die: defining the characteristics of serine protease-mediated cell death cascades Biochim Biophys Acta 1773 1491 1499 10.1016/j.bbamcr.2007.08.002
28. M Shukla 2006 Activation of calpains, calpastatin and spectrin cleavage in the brain during the pathology of fatal murine cerebral malaria Neurochem Int 48 108 113 10.1016/j.neuint.2005.09.001
29. S Smith 2001 The world according to PARP Trends Biochem Sci 26 174 179 10.1016/S0968-0004(00)01780-1
30. J Stefan Reid S Yigong 2004 Molecular mechanisms of Caspases during apoptosis Nat Rev Mol Cell Biol 5 897 907 10.1038/nrm1496
31. P Syntichaki 2005 The vacuolar H+ ATPase mediates intracellular acidification required for neurodegeneration inC. elegans Curr Biol 15 1249 1254 10.1016/j.cub.2005.05.057
32. KH Takeuchi 1992 Immunoassay and activity of calcium-activated neutral proteinase (mCANP): distribution in soluble and membrane-associated fractions in human and mouse brain J Neurochem 58 1526 1532 10.1111/j.1471-4159.1992. tb11374.x
33. SJ Van Wijk GJ Hageman 2005 Poly(ADP-ribose) polymerase-1 mediated caspase-independent cell death after ischemia/reperfusion Free Radic Biol Med 39 81 90 (Pubitemid 40733118)
34. L Virag C Szabo 2002 The therapeutic potential of poly(ADP-ribose) polymerase inhibitors Pharmacol Rev 54 375 429 10.1124/pr.54.3.375
35. KK Wang 2000 Calpain and caspase: can you tell the difference? Trends Neurosci 23 20 26 10.1016/S0166-2236(99)01479-4
36. L Xiuli 2004 The role of Calpain in oncotic cell death Annu Rev Pharmacol Toxicol 44 349 370 10.1146/annurev.pharmtox.44.101802.121804
37. M Yadaiah 2007 High affinity binding of Bcl-xL to cytochrome c: possible relevance for interception of translocated cytochrome c in apoptosis Biochim Biophys Acta 1774 1370 1379 (Pubitemid 350123198)
38. T Yamashima 2000 Implication of cysteine proteases calpain, cathepsin and caspase in ischemic neuronal death of primates Prog Neurobiol 62 273 295 10.1016/S0301-0082(00)00006-X
39. T Yamashima 2003 Sustained calpain activation is associated with lysosomal rupture executes necrosis of the post ischemic CA1 neurons in primates Hippocampus 13 791 800 10.1002/hipo.10127
40. G Yilmaz 2006 Role of T lymphocytes and interferon-gamma in ischemic stroke Circulation 113 2105 2112 10.1161/CIRCULATIONAHA.105.593046
41. HK Young 2007 Granzyme B leakage-induced apoptosis is a crucial mechanism of cell death in nasal-type NK/T-cell lymphoma Lab Invest 87 241 250 10.1038/labinvest.3700517
42. SW Yu 2006 Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death Proc Natl Acad Sci USA 103 18314 18319 10.1073/pnas.0606528103
43. M Ziegler SL Oei 2001 A cellular survival switch: poly(ADP-ribosyl)ation stimulates DNA repair and silences transcription Bioessays 23 543 548 10.1002/bies.1074