Tolerability and safety of enteral nutrition in critically ILL patients receiving intravenous vasopressor therapy

Journal of Parenteral and Enteral Nutrition

Volumn 37, Issue 5, 2013, Pages 641-651

  Mancl, Erin E ^a   Muzevich, Katie M ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

adult; critical illness; enteral nutrition; vasoconstrictor agents

Indexed keywords

ADRENALIN; DOPAMINE; HYPERTENSIVE FACTOR; LACTIC ACID; NORADRENALIN; PHENYLEPHRINE; VASOPRESSIN;

ADULT; AGED; ARTICLE; CRITICALLY ILL PATIENT; CYSTOGRAPHY; ENTERIC FEEDING; FEMALE; HUMAN; INTENSIVE CARE UNIT; INTESTINE ISCHEMIA; INTESTINE PERFORATION; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; OUTCOME ASSESSMENT; PATIENT SAFETY; PRIORITY JOURNAL; RENOGRAPHY; RETROSPECTIVE STUDY; TREATMENT DURATION; VOMITING;

ADULT; CRITICAL ILLNESS; ENTERAL NUTRITION; VASOCONSTRICTOR AGENTS;

ADMINISTRATION, INTRAVENOUS; ADULT; AGED; CRITICAL ILLNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENTERAL NUTRITION; FEMALE; GASTRIC STUMP; HUMANS; INTENSIVE CARE UNITS; LACTIC ACID; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NOREPINEPHRINE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; VASOCONSTRICTOR AGENTS; VOMITING;

EID: 84883502696     PISSN: 01486071     EISSN: None     Source Type: Journal    
DOI: 10.1177/0148607112470460     Document Type: Article

References (44)

1. McClave SA, Martindale RG, Vanek VW, et al. Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr. 2009 ; 33: 277-316
2. Kreymann KG, Berger MM, Deutz NE, et al. ESPEN guidelines on enteral nutrition: intensive care. Clin Nutr. 2006 ; 25: 210-223
3. Heyland DK, Dhaliwal R, Drover JW, Gramlich L, Dodek P. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN J Parenter Enteral Nutr. 2003 ; 27: 355-373
4. Doig GS, Heighes PT, Simpson F, Sweetman EA, Davies AR. Early enteral nutrition, provided within 24 h of injury or intensive care unit admission, significantly reduces mortality in critically ill patients: a meta-analysis of randomised controlled trials. Intensive Care Med. 2009 ; 35: 2018-2027
5. Mentec H, Dupont H, Bocchetti M, Cani P, Ponche F, Bleichner G. Upper digestive intolerance during enteral nutrition in critically ill patients: frequency, risk factors, and complications. Crit Care Med. 2001 ; 29: 1955-1961
6. Reilly PM, Bulkley GB. Vasoactive mediators and splanchnic perfusion. Crit Care Med. 1993 ; 21: S55 - S68
7. Seguin P, Laviolle B, Guinet P, Morel I, Malledant Y, Bellissant E. Dopexamine and norepinephrine versus epinephrine on gastric perfusion in patients with septic shock: a randomized study [NCT00134212]. Crit Care. 2006 ; 10: R32
8. Kazamias P, Kotzampassi K, Koufogiannis D, Eleftheriadis E. Influence of enteral nutrition-induced splanchnic hyperemia on the septic origin of splanchnic ischemia. World J Surg. 1998 ; 22: 6-11
9. McClave SA, Chang WK. Feeding the hypotensive patient: does enteral feeding precipitate or protect against ischemic bowel?. Nutr Clin Pract. 2003 ; 18: 279-284
10. Allen JM. Vasoactive substances and their effects on nutrition in the critically ill patient. Nutr Clin Pract. 2012 ; 27: 335-339
11. Berger MM, Berger-Gryllaki M, Wiesel PH, et al. Intestinal absorption in patients after cardiac surgery. Crit Care Med. 2000 ; 28: 2217-2223
12. Revelly JP, Tappy L, Berger MM, Gersbach P, Cayeux C, Chiolero R. Early metabolic and splanchnic responses to enteral nutrition in postoperative cardiac surgery patients with circulatory compromise. Intensive Care Med. 2001 ; 27: 540-547
13. Khalid I, Doshi P, DiGiovine B. Early enteral nutrition and outcomes of critically ill patients treated with vasopressors and mechanical ventilation. Am J Crit Care. 2010 ; 19: 261-268
14. Russell JA, Walley KR, Singer J, et al. Vasopressin versus norepinephrine infusion in patients with septic shock. N Engl J Med. 2008 ; 358: 877-887
15. Ensor CR, Sabo RT, Voils SA. Impact of early postoperative hydrocortisone administration in cardiac surgical patients after cardiopulmonary bypass. Ann Pharmacother. 2011 ;:
16. Lake Forest, IL: Akorn ; 2012 :
17. Stamford, CT: Purdue Pharma L.P. ; 2011 :
18. Moore FA, Cocanour CS, McKinley BA, et al. Migrating motility complexes persist after severe traumatic shock in patients who tolerate enteral nutrition. J Trauma. 2001 ; 51: 1075-1082
19. Kozar RA, McQuiggan MM, Moore EE, Kudsk KA, Jurkovich GJ, Moore FA. Postinjury enteral tolerance is reliably achieved by a standardized protocol. J Surg Res. 2002 ; 104: 70-75
20. Mutlu GM, Mutlu EA, Factor P. Prevention and treatment of gastrointestinal complications in patients on mechanical ventilation. Am J Respir Med. 2003 ; 2: 395-411
21. Gottschlich MM The A.S.P.E.N. Nutrition Support Core Curriculum: A Case-Based Approach: The Adult Patient. Silver Spring, MD: American Society for Parenteral and Enteral Nutrition ; 2007 :
22. Nygren A, Thoren A, Ricksten SE. Vasopressors and intestinal mucosal perfusion after cardiac surgery: norepinephrine vs. phenylephrine. Crit Care Med. 2006 ; 34: 722-729
23. Krejci V, Hiltebrand LB, Sigurdsson GH. Effects of epinephrine, norepinephrine, and phenylephrine on microcirculatory blood flow in the gastrointestinal tract in sepsis. Crit Care Med. 2006 ; 34: 1456-1463
24. Nygren A, Thoren A, Ricksten SE. Vasopressin decreases intestinal mucosal perfusion: a clinical study on cardiac surgery patients in vasodilatory shock. Acta Anaesthesiol Scand. 2009 ; 53: 581-588
25. Woolsey CA, Coopersmith CM. Vasoactive drugs and the gut: is there anything new?. Curr Opin Crit Care. 2006 ; 12: 155-159
26. Wells DL. Provision of enteral nutrition during vasopressor therapy for hemodynamic instability: an evidence-based review. Nutr Clin Pract. 2012 ; 27: 521-526
27. Klinzing S, Simon M, Reinhart K, Meier-Hellmann A, Sakr Y. Moderate-dose vasopressin therapy may impair gastric mucosal perfusion in severe sepsis: a pilot study. Anesthesiology. 2011 ; 114: 1396-1402
28. van Haren FM, Rozendaal FW, van der Hoeven JG. The effect of vasopressin on gastric perfusion in catecholamine-dependent patients in septic shock. Chest. 2003 ; 124: 2256-2260
29. Marik PE, Mohedin M. The contrasting effects of dopamine and norepinephrine on systemic and splanchnic oxygen utilization in hyperdynamic sepsis. JAMA. 1994 ; 272: 1354-1357
30. Dive A, Foret F, Jamart J, Bulpa P, Installe E. Effect of dopamine on gastrointestinal motility during critical illness. Intensive Care Med. 2000 ; 26: 901-907
31. Berger MM, Revelly JP, Cayeux MC, Chiolero RL. Enteral nutrition in critically ill patients with severe hemodynamic failure after cardiopulmonary bypass. Clin Nutr. 2005 ; 24: 124-132
32. Martikainen TJ, Tenhunen JJ, Giovannini I, Uusaro A, Ruokonen E. Epinephrine induces tissue perfusion deficit in porcine endotoxin shock: evaluation by regional CO2 content gradients and lactate-to-pyruvate ratios. Am J Physiol Gastrointest Liver Physiol. 2005 ; 288: G586 - G592
33. Kurz A, Sessler DI. Opioid-induced bowel dysfunction: pathophysiology and potential new therapies. Drugs. 2003 ; 63: 649-671
34. Bochicchio GV, Bochicchio K, Nehman S, Casey C, Andrews P, Scalea TM. Tolerance and efficacy of enteral nutrition in traumatic brain-injured patients induced into barbiturate coma. JPEN J Parenter Enteral Nutr. 2006 ; 30: 503-506
35. Heyland D, Cook DJ, Winder B, Brylowski L, Van deMark H, Guyatt G. Enteral nutrition in the critically ill patient: a prospective survey. Crit Care Med. 1995 ; 23: 1055-1060
36. Magnuson B, Hatton J, Zweng TN, Young B. Pentobarbital coma in neurosurgical patients: nutrition considerations. Nutr Clin Pract. 1994 ; 9: 146-150
37. Rhoney DH, Parker D, Formea CM, Yap C, Coplin WM. Tolerability of bolus versus continuous gastric feeding in brain-injured patients. Neurol Res. 2002 ; 24: 613-620
38. Stevens AM, Then JE, Frock KM, et al. Evaluation of feeding intolerance in patients with pentobarbital-induced coma. Ann Pharmacother. 2008 ; 42: 516-522
39. Fruhwald S, Holzer P, Metzler H. Intestinal motility disturbances in intensive care patients pathogenesis and clinical impact. Intensive Care Med. 2007 ; 33: 36-44
40. Ritz JP, Germer CT, Buhr HJ. Prognostic factors for mesenteric infarction: multivariate analysis of 187 patients with regard to patient age. Ann Vasc Surg. 2005 ; 19: 328-334
41. Maillet JM, Le Besnerais P, Cantoni M, et al. Frequency, risk factors, and outcome of hyperlactatemia after cardiac surgery. Chest. 2003 ; 123: 1361-1366
42. Raper RF, Cameron G, Walker D, Bowey CJ. Type B lactic acidosis following cardiopulmonary bypass. Crit Care Med. 1997 ; 25: 46-51
43. Totaro RJ, Raper RF. Epinephrine-induced lactic acidosis following cardiopulmonary bypass. Crit Care Med. 1997 ; 25: 1693-1699
44. James JH, Luchette FA, McCarter FD, Fischer JE. Lactate is an unreliable indicator of tissue hypoxia in injury or sepsis. Lancet. 1999 ; 354: 505-508