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Volumn 34, Issue 5, 2006, Pages 1456-1463

Effects of epinephrine, norepinephrine, and phenylephrine on microcirculatory blood flow in the gastrointestinal tract in sepsis

Author keywords

Intestine; Liver; Microcirculation; Pancreas; Vasoconstrictors

Indexed keywords

ADRENALIN; HYPERTENSIVE FACTOR; NORADRENALIN; PHENYLEPHRINE; VASOCONSTRICTOR AGENT;

EID: 33646547249     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000215834.48023.57     Document Type: Article
Times cited : (165)

References (46)
  • 1
    • 0027303116 scopus 로고
    • Hemodynamic and oxygen transport responses in survivors and nonsurvivors of high risk surgery
    • Shoemaker W, Appel P, Kram H: Hemodynamic and oxygen transport responses in survivors and nonsurvivors of high risk surgery. Crit Care Med 1993; 21:977-990
    • (1993) Crit Care Med , vol.21 , pp. 977-990
    • Shoemaker, W.1    Appel, P.2    Kram, H.3
  • 2
    • 0027427633 scopus 로고
    • A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high-risk surgical patients
    • Boyd O, Grounds M, Bennett E: A randomized clinical trial of the effect of deliberate perioperative increase of oxygen delivery on mortality in high-risk surgical patients. JAMA 1993; 270:2699-2707
    • (1993) JAMA , vol.270 , pp. 2699-2707
    • Boyd, O.1    Grounds, M.2    Bennett, E.3
  • 3
    • 0027202192 scopus 로고
    • Regional blood flow and oxygen transport in septic shock
    • Ruokonen E, Takala J, Kari A, et al: Regional blood flow and oxygen transport in septic shock. Crit Care Med 1993; 21:1296-1303
    • (1993) Crit Care Med , vol.21 , pp. 1296-1303
    • Ruokonen, E.1    Takala, J.2    Kari, A.3
  • 4
    • 0027411110 scopus 로고
    • Adequacy of gut oxygenation in endotoxemia and sepsis
    • Fink MP: Adequacy of gut oxygenation in endotoxemia and sepsis. Crit Care Med 1993; 21:S4-S8
    • (1993) Crit Care Med , vol.21
    • Fink, M.P.1
  • 5
    • 0032908255 scopus 로고    scopus 로고
    • Practice parameters for hemodynamic support of sepsis in adult patients in sepsis
    • Task Force of the American College of Critical Care Medicine, Society of Critical Care Medicine
    • Practice parameters for hemodynamic support of sepsis in adult patients in sepsis. Task Force of the American College of Critical Care Medicine, Society of Critical Care Medicine. Crit Care Med 1999; 27:639-660
    • (1999) Crit Care Med , vol.27 , pp. 639-660
  • 6
    • 0029078088 scopus 로고
    • Is translocation of bacteria and endotoxin from the gastrointestinal tract a source of sepsis in the critically ill?
    • Sigurdsson GH: Is translocation of bacteria and endotoxin from the gastrointestinal tract a source of sepsis in the critically ill? Acta Anaesthesiol Scand 1995; 39:11-19
    • (1995) Acta Anaesthesiol Scand , vol.39 , pp. 11-19
    • Sigurdsson, G.H.1
  • 7
    • 0032433470 scopus 로고    scopus 로고
    • Has the mortality of septic shock changed with time?
    • Friedman G, Silva E, Vincent JL: Has the mortality of septic shock changed with time? Crit Care Med 1998; 26:2078-2086
    • (1998) Crit Care Med , vol.26 , pp. 2078-2086
    • Friedman, G.1    Silva, E.2    Vincent, J.L.3
  • 8
    • 0030937226 scopus 로고    scopus 로고
    • Differential intestinal microvascular dysfunction occurs during bacteremia
    • Spain DA, Wilson MA, Krysztopik RJ, et al: Differential intestinal microvascular dysfunction occurs during bacteremia. J Surg Res 1997; 67:67-71
    • (1997) J Surg Res , vol.67 , pp. 67-71
    • Spain, D.A.1    Wilson, M.A.2    Krysztopik, R.J.3
  • 9
    • 0036009937 scopus 로고    scopus 로고
    • Modification of alpha1-adrenoceptors by peroxynitrite as a possible mechanism of systemic hypotension in sepsis
    • Takakura K, Taniguchi T, Muramatsu I, et al: Modification of alpha1-adrenoceptors by peroxynitrite as a possible mechanism of systemic hypotension in sepsis. Crit Care Med 2002; 30:894-899
    • (2002) Crit Care Med , vol.30 , pp. 894-899
    • Takakura, K.1    Taniguchi, T.2    Muramatsu, I.3
  • 10
    • 0032470559 scopus 로고    scopus 로고
    • Early effects of catecholamine therapy on mucosal integrity, intestinal blood flow, and oxygen metabolism in porcine endotoxin shock
    • Sautner T, Wessely C, Riegler M, et al: Early effects of catecholamine therapy on mucosal integrity, intestinal blood flow, and oxygen metabolism in porcine endotoxin shock. Ann Surg 1998; 228:239-248
    • (1998) Ann Surg , vol.228 , pp. 239-248
    • Sautner, T.1    Wessely, C.2    Riegler, M.3
  • 11
    • 0026777095 scopus 로고
    • Intestinal platelet sequestration after traumatic and septic shock. An early sign of sepsis and multiple organ failure in critically ill patients?
    • Sigurdsson GH, Christenson JT, El-Rakshy MB, et al: Intestinal platelet sequestration after traumatic and septic shock. An early sign of sepsis and multiple organ failure in critically ill patients? Crit Care Med 1992; 20:458-467
    • (1992) Crit Care Med , vol.20 , pp. 458-467
    • Sigurdsson, G.H.1    Christenson, J.T.2    El-Rakshy, M.B.3
  • 12
    • 0029091169 scopus 로고
    • Estimation of splanchnic blood flow by the Fick principle in man and problems in the use of indocyanine green
    • Uusaro A, Ruokonen E, Takala J: Estimation of splanchnic blood flow by the Fick principle in man and problems in the use of indocyanine green. Cardiovasc Res 1995; 30:106-112
    • (1995) Cardiovasc Res , vol.30 , pp. 106-112
    • Uusaro, A.1    Ruokonen, E.2    Takala, J.3
  • 13
    • 0032939471 scopus 로고    scopus 로고
    • Impact of exogenous beta-adrenergic receptor stimulation on hepatosplanchnic oxygen kinetics and metabolic activity in septic shock
    • Reinelt H, Radermacher P, Kiefer P, et al: Impact of exogenous beta-adrenergic receptor stimulation on hepatosplanchnic oxygen kinetics and metabolic activity in septic shock. Crit Care Med 1999; 27:325-331
    • (1999) Crit Care Med , vol.27 , pp. 325-331
    • Reinelt, H.1    Radermacher, P.2    Kiefer, P.3
  • 14
    • 0035209881 scopus 로고    scopus 로고
    • Variability of splanchnic blood flow measurements in patients with sepsis - Physiology, pathophysiology or measurement errors?
    • Jakob SM, Takala J: Variability of splanchnic blood flow measurements in patients with sepsis - Physiology, pathophysiology or measurement errors? Intensive Care Med 2001; 27:1692-1695
    • (2001) Intensive Care Med , vol.27 , pp. 1692-1695
    • Jakob, S.M.1    Takala, J.2
  • 15
    • 0034884360 scopus 로고    scopus 로고
    • Variability of splanchnic blood flow in patients with sepsis
    • Sakka SG, Reinhart K, Wegscheider K, et al: Variability of splanchnic blood flow in patients with sepsis. Intensive Care Med 2001; 27:1281-1287
    • (2001) Intensive Care Med , vol.27 , pp. 1281-1287
    • Sakka, S.G.1    Reinhart, K.2    Wegscheider, K.3
  • 16
    • 0036095413 scopus 로고    scopus 로고
    • Effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shock
    • Seguin P, Bellissant E, Le Tulzo Y, et al: Effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shock. Clin Pharmacol Ther 2002; 71:381-388
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 381-388
    • Seguin, P.1    Bellissant, E.2    Le Tulzo, Y.3
  • 17
    • 0032993718 scopus 로고    scopus 로고
    • Effects of epinephrine, norepinephrine, or the combination of norepinephrine and dobutamine on gastric mucosa in septic shock
    • Duranteau J, Sitbon P, Teboul J, et al: Effects of epinephrine, norepinephrine, or the combination of norepinephrine and dobutamine on gastric mucosa in septic shock. Crit Care Med 1999; 27:893-900
    • (1999) Crit Care Med , vol.27 , pp. 893-900
    • Duranteau, J.1    Sitbon, P.2    Teboul, J.3
  • 18
    • 0033796625 scopus 로고    scopus 로고
    • Dynamic study of the distribution of microcirculatory blood flow in multiple splanchnic organs in septic shock
    • Hiltebrand LB, Krejci V, Banic A, et al: Dynamic study of the distribution of microcirculatory blood flow in multiple splanchnic organs in septic shock. Crit Care Med 2000; 28:3233-3241
    • (2000) Crit Care Med , vol.28 , pp. 3233-3241
    • Hiltebrand, L.B.1    Krejci, V.2    Banic, A.3
  • 19
    • 0022032951 scopus 로고
    • Splenic red cell sequestration and blood volume measurements in conscious pigs
    • Hannon JP, Bossone CA, Rodkey WG: Splenic red cell sequestration and blood volume measurements in conscious pigs. Am J Physiol 1985; 248:R293-R301
    • (1985) Am J Physiol , vol.248
    • Hannon, J.P.1    Bossone, C.A.2    Rodkey, W.G.3
  • 20
    • 0028029207 scopus 로고
    • Splanchnic tonometry: A review of physiology, methodology, and clinical applications
    • Groeneveld AB, Kolkman JJ: Splanchnic tonometry: A review of physiology, methodology, and clinical applications. J Crit Care 1994; 9:198-210
    • (1994) J Crit Care , vol.9 , pp. 198-210
    • Groeneveld, A.B.1    Kolkman, J.J.2
  • 21
    • 0026513626 scopus 로고
    • Measurement of hepatic perfusion in rats by laser Doppler flowmetry
    • Almond NE, Wheatley AM: Measurement of hepatic perfusion in rats by laser Doppler flowmetry. Am J Physiol 1992; 262:G203-G209
    • (1992) Am J Physiol , vol.262
    • Almond, N.E.1    Wheatley, A.M.2
  • 22
    • 0031922663 scopus 로고    scopus 로고
    • Dissociation between volume blood flow and laser-Doppler signal from rat muscle during changes in vascular tone
    • Kuznetsova LV, Tomasek N, Sigurdsson GH, et al: Dissociation between volume blood flow and laser-Doppler signal from rat muscle during changes in vascular tone. Am J Physiol 1998; 274:H1248-H1254
    • (1998) Am J Physiol , vol.274
    • Kuznetsova, L.V.1    Tomasek, N.2    Sigurdsson, G.H.3
  • 23
    • 4444233598 scopus 로고    scopus 로고
    • Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock
    • Sakr Y, Dubois MJ, De Backer D, et al: Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock. Crit Care Med 2004; 32:1825-1831
    • (2004) Crit Care Med , vol.32 , pp. 1825-1831
    • Sakr, Y.1    Dubois, M.J.2    De Backer, D.3
  • 24
    • 0037373495 scopus 로고    scopus 로고
    • Redistribution of microcirculatory blood flow within the intestinal wall during sepsis and general anesthesia
    • Hiltebrand L, Krejci V, Ten Hoevel M, et al: Redistribution of microcirculatory blood flow within the intestinal wall during sepsis and general anesthesia. Anesthesiology 2003; 98:658-669
    • (2003) Anesthesiology , vol.98 , pp. 658-669
    • Hiltebrand, L.1    Krejci, V.2    Ten Hoevel, M.3
  • 25
    • 0020026713 scopus 로고
    • The pig model for biomedical research
    • Dodds W: The pig model for biomedical research. Fed Proc 1982; 41:247-256
    • (1982) Fed Proc , vol.41 , pp. 247-256
    • Dodds, W.1
  • 26
    • 0022869705 scopus 로고
    • Autoregulation of blood flow
    • Johnson P: Autoregulation of blood flow. Circ Res 1986; 59:483-495
    • (1986) Circ Res , vol.59 , pp. 483-495
    • Johnson, P.1
  • 27
    • 17044419279 scopus 로고    scopus 로고
    • Arterial pressure, vasopressors and septic shock: Higher is not necessarily better
    • Reisbeck M, Astiz ME: Arterial pressure, vasopressors and septic shock: Higher is not necessarily better. Crit Care Med 2005; 33:906-907
    • (2005) Crit Care Med , vol.33 , pp. 906-907
    • Reisbeck, M.1    Astiz, M.E.2
  • 28
    • 0024410955 scopus 로고
    • Norepinephrine therapy has no deleterious renal effects in human septic shock
    • Desjars P, Pinaud M, Bugnon D, et al: Norepinephrine therapy has no deleterious renal effects in human septic shock. Crit Care Med 1989; 17:426-429
    • (1989) Crit Care Med , vol.17 , pp. 426-429
    • Desjars, P.1    Pinaud, M.2    Bugnon, D.3
  • 29
    • 0025239776 scopus 로고
    • Renal effects of norepinephrine used to treat septic shock
    • Marin C, Eon B, Akin P, et al: Renal effects of norepinephrine used to treat septic shock. Crit Care Med 1990; 18:282-285
    • (1990) Crit Care Med , vol.18 , pp. 282-285
    • Marin, C.1    Eon, B.2    Akin, P.3
  • 30
    • 0033847206 scopus 로고    scopus 로고
    • Effects of perfusion pressure on tissue perfusion in septic shock
    • Ledoux D, Astiz M, Carpati C, et al: Effects of perfusion pressure on tissue perfusion in septic shock. Crit Care Med 2000; 28:2729-2732
    • (2000) Crit Care Med , vol.28 , pp. 2729-2732
    • Ledoux, D.1    Astiz, M.2    Carpati, C.3
  • 31
    • 17044421757 scopus 로고    scopus 로고
    • Increasing mean arterial pressure in patients with septic shock: Effects on oxygen variables and renal function
    • Bourgoin A, Leone M, Delmas A, et al: Increasing mean arterial pressure in patients with septic shock: Effects on oxygen variables and renal function. Crit Care Med 2005; 33:780-786
    • (2005) Crit Care Med , vol.33 , pp. 780-786
    • Bourgoin, A.1    Leone, M.2    Delmas, A.3
  • 32
    • 4444225425 scopus 로고    scopus 로고
    • Practice parameters for hemodynamic support of sepsis in adult patients
    • Task Force of the American College of Critical Care Medicine
    • Hollenberg SM, Ahrens TS, Annane D, et al: Task Force of the American College of Critical Care Medicine. Practice parameters for hemodynamic support of sepsis in adult patients. Crit Care Med 2004; 32:1928-1948
    • (2004) Crit Care Med , vol.32 , pp. 1928-1948
    • Hollenberg, S.M.1    Ahrens, T.S.2    Annane, D.3
  • 33
    • 0037253077 scopus 로고    scopus 로고
    • Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock
    • Krejci V, Hiltebrand LB, Erni D, et al: Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock. Crit Care Med 2003; 31:203-210
    • (2003) Crit Care Med , vol.31 , pp. 203-210
    • Krejci, V.1    Hiltebrand, L.B.2    Erni, D.3
  • 34
    • 0024262636 scopus 로고
    • Intramural distribution of intestinal blood flow during sympathetic stimulation
    • Shepherd AP, Riedel GL: Intramural distribution of intestinal blood flow during sympathetic stimulation. Am J Physiol 1988; 255:H1091-H1095
    • (1988) Am J Physiol , vol.255
    • Shepherd, A.P.1    Riedel, G.L.2
  • 35
    • 0032622384 scopus 로고    scopus 로고
    • Effects of sodium nitroprusside and phenylephrine on blood flow in free musculocutaneous flaps during general anesthesia
    • Banic A, Krejci V, Erni D, et al: Effects of sodium nitroprusside and phenylephrine on blood flow in free musculocutaneous flaps during general anesthesia. Anesthesiology 1999; 90:147-155
    • (1999) Anesthesiology , vol.90 , pp. 147-155
    • Banic, A.1    Krejci, V.2    Erni, D.3
  • 36
    • 0030751832 scopus 로고    scopus 로고
    • A dose-response study of phenylephrine in critically ill, septic surgical patients
    • Flancbaum L, Dick M, Dasta J, et al: A dose-response study of phenylephrine in critically ill, septic surgical patients. Eur J Clin Pharmacol 1997; 51:461-465
    • (1997) Eur J Clin Pharmacol , vol.51 , pp. 461-465
    • Flancbaum, L.1    Dick, M.2    Dasta, J.3
  • 37
    • 0025933264 scopus 로고
    • Experience with phenylephrine as a component of the pharmacologic support of septic shock
    • Gregory J, Bonfiglio M, Dasta J, et al: Experience with phenylephrine as a component of the pharmacologic support of septic shock. Crit Care Med 1991; 19:1395-1400
    • (1991) Crit Care Med , vol.19 , pp. 1395-1400
    • Gregory, J.1    Bonfiglio, M.2    Dasta, J.3
  • 38
    • 0027193744 scopus 로고
    • Spectrophotometric study of alpha-adrenoceptors affecting microcirculation of rat skin
    • Kakizoe E, Kobayashi Y, Shimoura K, et al: Spectrophotometric study of alpha-adrenoceptors affecting microcirculation of rat skin. Clin Exp Pharmacol Physiol 1993; 20:421-427
    • (1993) Clin Exp Pharmacol Physiol , vol.20 , pp. 421-427
    • Kakizoe, E.1    Kobayashi, Y.2    Shimoura, K.3
  • 39
    • 0033792023 scopus 로고    scopus 로고
    • Effects of maximizing oxygen delivery on morbidity and mortality in high-risk surgical patients
    • Lobo SM, Salgado PF, Castillo VG, et al: Effects of maximizing oxygen delivery on morbidity and mortality in high-risk surgical patients. Crit Care Med 2000; 28:3396-3404
    • (2000) Crit Care Med , vol.28 , pp. 3396-3404
    • Lobo, S.M.1    Salgado, P.F.2    Castillo, V.G.3
  • 40
    • 0027247627 scopus 로고
    • Effect of maximizing oxygen delivery on morbidity and mortality rates in critically ill patients: A prospective, randomized, controlled study
    • Yu M, Levy MM, Smith P, et al: Effect of maximizing oxygen delivery on morbidity and mortality rates in critically ill patients: A prospective, randomized, controlled study. Crit Care Med 1993; 21:830-838
    • (1993) Crit Care Med , vol.21 , pp. 830-838
    • Yu, M.1    Levy, M.M.2    Smith, P.3
  • 41
    • 0032042009 scopus 로고    scopus 로고
    • Does hepato-splanchnic VO2/DO2 dependency exist in critically ill septic patients?
    • De Backer D, Creteur J, Noordally O, et al: Does hepato-splanchnic VO2/DO2 dependency exist in critically ill septic patients? Am J Respir Crit Care Med 1998; 157:1219-1225
    • (1998) Am J Respir Crit Care Med , vol.157 , pp. 1219-1225
    • De Backer, D.1    Creteur, J.2    Noordally, O.3
  • 42
    • 0028872009 scopus 로고
    • A trial of goal-oriented hemodynamic therapy in critically ill patients
    • SvO2 Collaborative Group
    • Gattinoni L, Brazzi L, Pelosi P, et al: A trial of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. N Engl J Med 1995; 333:1025-1032
    • (1995) N Engl J Med , vol.333 , pp. 1025-1032
    • Gattinoni, L.1    Brazzi, L.2    Pelosi, P.3
  • 43
    • 0032935958 scopus 로고    scopus 로고
    • A randomized and controlled trial of the effect of treatment aimed at maximizing oxygen delivery in patients with severe sepsis or septic shock
    • Alia I, Esteban A, Gordo F, et al: A randomized and controlled trial of the effect of treatment aimed at maximizing oxygen delivery in patients with severe sepsis or septic shock. Chest 1999; 115:453-461
    • (1999) Chest , vol.115 , pp. 453-461
    • Alia, I.1    Esteban, A.2    Gordo, F.3
  • 44
    • 0030965638 scopus 로고    scopus 로고
    • Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: A prospective, randomized study
    • Levy B, Bollaert P, Charpentier C, et al: Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: A prospective, randomized study. Intensive Care Med 1997; 23:282-287
    • (1997) Intensive Care Med , vol.23 , pp. 282-287
    • Levy, B.1    Bollaert, P.2    Charpentier, C.3
  • 45
    • 0034244108 scopus 로고    scopus 로고
    • Prevention of systemic hyperlactatemia during splanchnic ischemia
    • Jakob SM, Merasto-Minkkinen M, Tenhunen JJ, et al: Prevention of systemic hyperlactatemia during splanchnic ischemia. Shock 2000; 14:123-127
    • (2000) Shock , vol.14 , pp. 123-127
    • Jakob, S.M.1    Merasto-Minkkinen, M.2    Tenhunen, J.J.3
  • 46
    • 0031000027 scopus 로고    scopus 로고
    • Epinephrine impairs splanchnic perfusion in septic shock
    • Meier-Hellmann A, Reinhart K, Bredle DL, et al: Epinephrine impairs splanchnic perfusion in septic shock. Crit Care Med 1997; 25:399-404
    • (1997) Crit Care Med , vol.25 , pp. 399-404
    • Meier-Hellmann, A.1    Reinhart, K.2    Bredle, D.L.3


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